Clinical trials: Breast Cancer Detection
Carcinoma, Intraductal, Noninfiltrating
Multimodal Imaging With FAPI-PET/MRI in Breast Carcinoma-In-Situ for Detection of Occult Invasive Cancer
DCIS (ductal carcinoma in situ) is a common pre-stage for breast cancer. The goal of this clinical trial is to learn if FAPI-PET/MRI (an imaging technique with a weakly radioactive drug) helps to diagnose hidden invasive breast…
- Trial name
- MI-CISDIR (NCT06540872)
- Testing
- [68Ga]Ga-FAPI-46
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Universität Münster
Cardiotoxicity, Breast Cancer
Identification of Novel Inflammation-related Biomarkers for Early Detection of Anthracycline-induced Cardiotoxicity in Breast Cancer Patients
This study aims to identify possible set of inflammatory biomarkers before, during and after anthracycline-based chemotherapy in breast cancer patients to identify (sub)clinical chemotherapy-related cardiac dysfunctionCRCD to…
- Conditions
- Cardiotoxicity, Breast Cancer, Heart Failure
- Trial name
- NCT05298072
- Volunteers
- 180 people
- Sponsor
- University Hospital, Essen
Breast Neoplasms, Breast Cancer
Comparison of Ultrasound and Breast MRI for Breast Cancer Detection
The goal of this randomized clinical trial is to compare diagnostic results of secondary breast cancer surveillance using breast ultrasound abbreviated MRI and full protocol MRI.
- Trial name
- NCT05797545
- Testing
- Breast MRI for Breast Cancer Detection
- Where
- 3 sites in South Korea
- Volunteers
- 1,756 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Breast Cancer
Investigation of Novel Surgical Imaging for Tumor Excision
This is a multi-center, two-arm randomized, blinded pivotal study to demonstrate the safety and efficacy of the LUM Imaging System (LUM015 imaging agent in conjunction with the LUM Imaging Device and decision software), in…
- Trial name
- INSITE (NCT03686215)
- Testing
- Study Device Arm
- Where
- 14 sites in United States
- Volunteers
- 406 people
- Sponsor
- Lumicell, Inc.
Cancer
PERformance of Multi-Cancer Early-detectIon Based on Various Biomarkers in fEmale BREAST Cancers, PERCEIVE-BREAST
This study is a retrospective and prospective study aimed to develop and validate the performance of multi-omics assays for early detection of female breast cancer.
- Trial name
- NCT06979921
- Testing
- Blood test
- Where
- 2 sites in China
- Volunteers
- 496 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Breast Cancer, Tear
Tear Based Sample Collection Breast Cancer Detection
This study aims to collect tear samples from 50 women who have been recently diagnosed with breast cancer.
- Conditions
- Breast Cancer, Tear, Breast Cancer Female
- Trial name
- NCT04974567
- Testing
- Schirmer Strip
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Namida Lab
Breast Cancer, Breast Cancer Female
SNAPS Breast Cancer Patient Study Breast Cancer Patients
Differential immunogenomic signatures from peripheral blood CD14 (phagocytic) and CD2 (non-phagocytic) cells have been associated with multiple cancers and disease states.
- Trial name
- NCT05370300
- Testing
- Blood test
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Immunis.AI
Breast Cancer
A Clinical Study to Evaluate Somo•v and Digital Mammography Together as a Breast Cancer Screening Method, Compared to Digital Mammography Alone, in Women With Dense Breasts.
Hypothesis: A higher sensitivity to breast cancer detection can be achieved in women with dense breast tissue by performing and reviewing results of Automated Breast Ultrasound (ABUS) and Digital X-Ray Mammography (XRM) together…
- Trial name
- somo•InSIGHT (NCT00816530)
- Testing
- Automated Breast Ultrasound (ABUS) as an adjunct to digital screening mammography
- Where
- 11 sites in United States
- Volunteers
- 15,679 people
- Sponsor
- U-Systems, Inc.
Breast Disease, Benign Breast Disease
Effectiveness Validation of CELBREA® in Symptomatic Women or With Diagnostic Doubt of Breast Pathology (DETECT-BH)
This is an observational, prospective, and transversal study, designed to evaluate the effectiveness of CELBREA® in women from the local community coming to consult at the Breast Pathology Unit of La Paz Hospital (Madrid, Spain)…
- Conditions
- Breast Disease, Benign Breast Disease, Breast Cancer
- Trial name
- DETECT-BH (NCT05857111)
- Testing
- Celbrea
- Where
- Spain
- Volunteers
- 255 people
- Sponsor
- Jose Ignacio Sánchez
Ovarian Cancer, Breast Cancer
Cancer Screening and Prevention Program for High Risk Women
The purpose of this study is to collect information from a large group of women who may have a greater chance to develop cancer because of their own personal history of cancer or because of their family history of cancer.
- Trial name
- NCT00849199
- Where
- 3 sites in United States
- Volunteers
- 1,452 people
- Sponsor
- NYU Langone Health
Sentinel Lymph Node
Cost of Using FLUOrescence to Green of Indocyanine for the Detection of Breast Cancer.
The purpose of this study is to analyze the average direct costs of each of these techniques, represented by the costs directly linked to the management of breast cancer, to the surgical intervention and to the techniques…
- Trial name
- FLUOBREAST-2 (NCT05699291)
- Testing
- Sentinel node detection technique
- Where
- France
- Volunteers
- 163 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Breast Cancer
Personalized Breast Cancer Screening
The purpose of the study is to measure short-term safety and efficacy of personalized vs. standard mammography screening among 50-67-year aged women.
- Trial name
- PRSONAL (NCT06060938)
- Testing
- Risk stratified arm, Control arm
- Where
- Denmark
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Breast Cancer Organoids
Breast Cancer Treatment Based on Organ-like Culture
Based on the breast cancer organ platform, this experiment establishes a drug sensitivity test method that is closer to the body tumor in breast cancer, provides a basis for the accurate treatment of breast cancer, and discusses…
- Trial name
- NCT03925233
- Testing
- Trastuzumab, Doxorubicin Hydrochloride, Epirubicin hydrochloride
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Breast Cancer, Early Detection of Cancer
Strategies to Decentralize Breast Ultrasound in Rwanda
Diagnosing breast cancer early is critical to reduce preventable breast cancer deaths in sub-Saharan Africa. This can be done in part through increasing patients' access to breast ultrasound, which is essential for evaluating…
- Conditions
- Breast Cancer, Early Detection of Cancer, Ultrasonography
- Trial name
- NCT06812208
- Testing
- Teleultrasound with Philips Lumify ultrasound probes and Reacts software, Asynchronous virtual feedback
- Where
- Rwanda
- Volunteers
- 1,792 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Case Collection Study for Collecting Images for the Development and Validation of Computer Aided Detection Software
The study objective is to assess the performance of the MammoDetector Pro to correctly mark biopsy-proven breast cancers imaged on the Siemens Mammomat Novation FFDM system compared to conventional film-screen mammography.
- Trial name
- NCT00756834
- Testing
- Screening
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Siemens Medical Solutions
Breast Cancer, Axillary Nodal Disease
IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases
The purpose of the study is to determine the recurrence rates and survival of patients with clinical T1-2N0 ER+/Her2- invasive breast cancer who have biopsy proven image detected nodal disease treated with upfront lumpectomy or…
- Conditions
- Breast Cancer, Axillary Nodal Disease, Female Breast Cancer, Axilla; Breast
- Trial name
- NCT06092892
- Testing
- Breast Surgery (BCS or mastectomy) with TAD/SNB, Adjuvant Radiation Therapy
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Alice Chung
Relationship and Consistency Analysis
Recurrence Risk Evaluation by 21-gene Detection
Breast cancer patients with early breast cancer were enrolled according to the inclusion criteria. Baseline characteristics were recorded from medical record system.
- Trial name
- NCT03841266
- Testing
- recurrence risk evaluation
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Xijing Hospital
Breast Neoplasms
Use of Bone Scintigraphy, CT and MRI in Breast Cancer
A new imaging modality combining CT and tomographic bone scintigraphy (SPECT/CT) has enabled the combination of functional and anatomical imaging.
- Trial name
- NCT00682253
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- University of Aarhus
Breast Cancer
Clinical Investigation to Evaluate the Ability of MammoWave in Breast Lesions Detection
This is a multicentric, single arm, prospective, stratified by breast density clinical investigation using Mammowave that is a device, which uses microwaves instead of ionizing radiation (X-ray)for breast lesions(BL) detection.
- Trial name
- DE-17-17 (NCT04253366)
- Testing
- Clinical investigation device class IIa not marked CE
- Where
- 3 sites in Italy, Spain
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Umbria Bioengineering Technologies
Device, Thermography
Study To Evaluate The Sensitivity Of The Linda Thermal Device
The LINDA thermal device consists of a thermal camera attachable to a cell phone and an application for connection with an artificial intelligence program based on a convolutional neural network for classification of…
- Conditions
- Device, Thermography, Mammography
- Trial name
- LINDA (NCT05009277)
- Testing
- Device
- Where
- Brazil
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Azidus Brasil