Clinical trials: Brain Injury
Cerebral Palsy
Effects of Music Therapy in Children With Cerebral Palsy
Purpose:To observe the effects of music therapy on gross motor functions, pain and functional independence measurement in children with cerebral palsy(CP).
- Trial name
- NCT03640585
- Testing
- Music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Bilgi University
Brain Injury
Effects of Viral Reactivation on Outcomes of Brain-injured Patients ( IBIS-VIRUS)
Morbidity and mortality of ICU patients is increased by the development of a "immunosuppression" systemic (IS). This IS develops in the early hours of hospitalization and is responsible for severe infections, including viral…
- Trial name
- IBIS-VIRUS (NCT02003196)
- Where
- France
- Volunteers
- 375 people
- Sponsor
- Nantes University Hospital
Cerebral Palsy (CP)
The Effect of Robot-assisted Walking Training on Motor Functions, Respiratory Parameters and Functional Capacity in Cerebral Palsy
An informed consent form was prepared for families regarding the planned research. Permission and signatures were obtained from the parents of children aged 8-16 years who participated in the study.
- Trial name
- NCT07469696
- Testing
- robotic rehabilitation and intensive spirometry, spirometer spirobank
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul University - Cerrahpasa
Cerebral Palsy
ePrime: Evaluation of Magnetic Resonance (MR) Imaging to Predict Neurodevelopmental Impairment in Preterm Infants
Preterm infants face an uncertain future because premature birth often leads to problems with brain development and can cause cerebral palsy.
- Trial name
- ePrime (NCT01049594)
- Where
- 13 sites in United Kingdom
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Stroke, Spinal Cord Injuries (Complete and Incomplete)
EMG-Directed Virtual-Reality Training for Motor Stroke Rehabilitation
This study is testing whether rehabilitation using muscle activity signals can help improve arm and hand movement in people after stroke or spinal cord injury.
- Trial name
- NCT07705256
- Testing
- Visual EMG feedback with vibrotactile feedback, Visual EMG feedback
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Imperial College London
Brain Injury
Combining Observational and Physiologic Sedation Assessment Tools
When a physiologic tool to measure the patient's hypnotic state is added to current practice tools is there a decrease in the amount of drug the patient receives.
- Trial name
- COST (NCT00538369)
- Testing
- Ramsay Scale, Bispectral index monitor
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Duke University
Autonomic Dysreflexia
Fesoterodine for Amelioration of Autonomic Dysreflexia (AD) Following Spinal Cord Injury (SCI)
This study will be investigating the effects of fesoterodine on autonomic dysreflexia (AD) in patients with spinal cord injuries (SCI).
- Trial name
- NCT02676154
- Testing
- Fesoterodine
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Cerebral Palsy, Congenital
Effects of Hippotherapy in Children With Cerebral Palsy
Cerebral palsy is a group of permanent disorders affecting movement and posture due to non-progressive disturbances in the developing brain.
- Trial name
- NCT07739680
- Testing
- Hippotherapy Program, Special Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
Cerebral Palsy, Chronic Pain
Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy
The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP.
- Trial name
- NCT05197946
- Testing
- MRI
- Where
- 4 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Hemiplegic Cerebral Palsy, Non-Accidental Traumatic Head Injury to Child
Intensive Group Based CIMT for Young Children
This project aims to investigate the effectiveness of an intensive, group-based Constraint Induced Movement Therapy (CIMT) program for young children ages 2-6 years with unilateral hemiparesis, or weakness on one side of the…
- Trial name
- NCT06330831
- Testing
- Intensive, Group Based Constraint Induced Therapy (CIMT)
- Volunteers
- 35 people
- Sponsor
- Rockhurst University
Brain Edema, Craniocerebral Trauma
A Comparison Between Two Techniques for Performing Decompressive Craniectomy
The purpose of this study is to compare two surgical techniques for a neurosurgical procedure used to treat cerebral edema (decompressive craniectomy): with watertight duraplasty vs.
- Conditions
- Brain Edema, Craniocerebral Trauma, Infarction, Middle Cerebral Artery
- Trial name
- NCT02594137
- Testing
- Without watertight duraplasty
- Volunteers
- 58 people
- Sponsor
- Hospital of the Restoration, Recife
Tinnitus
Telephone Tinnitus Education for Patients With Traumatic Brain Injury (TBI)
This study continues the investigators' efforts to develop tinnitus management protocols for Veterans. More specifically, this study developed and evaluated an adaptation of Progressive Tinnitus Management (PTM) for use as a…
- Trial name
- NCT01129141
- Testing
- Tele-PTM, Wait List Control
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- VA Office of Research and Development
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Cerebral Palsy, Walking, Difficulty
A Motor Learning Intervention to Target Walking Performance in Ambulant Children With Cerebral Palsy
The goal of this clinical trial is to learn if a new therapy approach to improve walking ability in children with Cerebral Palsy is acceptable to the children and the families in a community setting.
- Conditions
- Cerebral Palsy, Walking, Difficulty, Spastic Diplegia, Hemiplegic Cerebral Palsy
- Trial name
- MOBILE (NCT06454656)
- Testing
- MOBILE
- Where
- Ireland
- Volunteers
- 14 people
- Sponsor
- Royal College of Surgeons, Ireland
Brain Damage Due to Hypoxia, Organ Donors
Endothelial Glycocalyx Damage in Brain Death Organ Donors
The study aims the assessment of endothelial glycocalyx (EG) degradation in deceased organ donors. There is a lack of organs for the transplantation program.
- Conditions
- Brain Damage Due to Hypoxia, Organ Donors, Organ Transplant Failure or Rejection
- Trial name
- NCT05609123
- Testing
- Endothelial glycocalyx damage assessment
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Hradec Kralove
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Cerebral Palsy
Effects of Intensive Locomotor Treadmill Training on Gross Motor Function in Young Children With Neuromotor Impairment
The purpose of this project is to examine if early exposure to intensive, short-term locomotor treadmill training (LT) in young children with neuromotor impairment will help develop walking skills earlier, decrease the amount of…
- Trial name
- NCT01732731
- Testing
- treadmill training
- Volunteers
- 12 people
- Sponsor
- University of the Pacific
Traumatic Brain Injury
Effects of Exercise on Memory in Healthy and Brain-Injured Individuals
Background: Research has shown that one exercise session may improve a person s ability to recall information they learned before the exercise.
- Trial name
- NCT01939769
- Testing
- Exercise - Low-intensity exercise, Exercise - High-intensity exercise
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Spastic Cerebral Palsy
Prospective Studies of the Use of Self Hypnosis, Acupuncture and Osteopathic Manipulation on Muscle Tension in Children With Spastic Cerebral Palsy
We propose to identify patients and families for inclusion in pilot studies of the three modalities. Patients and their families will be asked to participate in these studies.
- Trial name
- NCT00011024
- Testing
- Self Hypnosis, Acupuncture, Osteopathic Manipulation
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Sport Related Concussion
Salivary Biomarkers for Concussion
Concussion (CC) (also called mild head trauma), which accounts for 85% of all head injuries, is very common in professional and amateur athletes.
- Trial name
- SportCo (NCT06149351)
- Testing
- Bio-fluid analysis for the implementation of a diagnostic test for sport related concussion
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sys2Diag