Clinical trials: Brain Infarction
Myocardial Infarction, Angina Pectoris
Improving Intermediate Risk Management. MARK Study
Cardiovascular risk functions fail to identify more than 50% of patients who develop cardiovascular disease. This is especially evident in the intermediate-risk patients in which clinical management becomes difficult.
- Conditions
- Myocardial Infarction, Angina Pectoris, Stroke, Peripheral Arterial Disease
- Trial name
- MARK (NCT01428934)
- Where
- Spain
- Volunteers
- 2,495 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cerebral Infarction, TIA
Early Rivaroxaban for Acute Ischemic Stroke or TIA Patients With Atrial Fibrillation
Anticoagulant treatment for non-valvular atrial fibrillation (AF) associated with cerebral infarction/ TIA is one of the recognized treatment of stroke prevention.
- Trial name
- ERSAF (NCT03749057)
- Testing
- Rivaroxaban
- Where
- China
- Volunteers
- 400 people
- Sponsor
- General Hospital of Shenyang Military Region
Stroke, AMI
The Pilot Project Development Of MEdical Rehabilitation System in Russian Federation
The Programme is focused on adult patients of any gender and age more than 18 y.o., with the next conditions: 1. Acute cerebrovascular events (ACE, ischemic stroke or intracerebral hemorrhage - specialty neurology) 2.
- Conditions
- Stroke, AMI, Total Hip Replacement
- Trial name
- NCT02793934
- Testing
- Scales, New model of rehabilitation, Old model of rehabilitation
- Where
- Russia
- Volunteers
- 2,000 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Brain Infarction, Transient Ischemic Attack
Aortic Arch Related Cerebral Hazard Trial (ARCH)
The ARCH is a controlled trial with a sequential design and with a prospective, randomized, open-label, blinded-endpoint (PROBE) methodology.
- Conditions
- Brain Infarction, Transient Ischemic Attack, Embolism
- Trial name
- ARCH (NCT00235248)
- Testing
- Warfarin, Clopidogrel-aspirin
- Where
- 2 sites in Australia, France
- Volunteers
- 350 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thrombosis, Atherothrombosis
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer
To date, the investigators have successfully employed a radiotracer (18F-sodium fluoride) as a marker of necrotic inflammation in human atherosclerosis.
- Conditions
- Thrombosis, Atherothrombosis, Myocardial Infarction, STEMI
- Trial name
- iThrombus (NCT03943966)
- Testing
- 18F-GP1 PET CT
- Where
- United Kingdom
- Volunteers
- 73 people
- Sponsor
- University of Edinburgh
Stroke, Transient Ischemic Attack
Optimal Blood Pressure and Cholesterol Targets for Preventing Recurrent Stroke in Hypertensives
Stroke is one of the major causes not only of mortality, but of disease burden worldwide, because of residual disability and cognitive decline.
- Conditions
- Stroke, Transient Ischemic Attack, Hypertension
- Trial name
- ESH-CHL-SHOT (NCT01563731)
- Testing
- all approved antihypertensive drugs; all approved statins
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Istituto Auxologico Italiano
Cerebral Infarction
Thrombus Analysis of Ischemic Stroke
Patients with acute ischemic stroke who have undergone endovascular thrombectomy will be eligible to be included, and thrombus will be collected after obtaining informed consent.
- Trial name
- TAOIST (NCT07043413)
- Testing
- thrombus analysis
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Hospital
Cerebral Infarction, Disease
A Multi-center Prospective Study of Branch Atheromatous Disease in China
Branch atheromatous disease (BAD), is regarded as one of the important etiologies for acute isolated subcortical infarction, especially in Asian population.
- Conditions
- Cerebral Infarction, Disease, Magnetic Resonance Imaging
- Trial name
- NCT04973774
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking Union Medical College Hospital
Cardiovascular Diseases, Cerebral Infarction
Screening, Early Referral and Lifestyle Tailored E_prescription for Cardiovascular Prevention
We will evaluate an e_Prescription intervention can be integrated into an electronic screening program, which together exploit: (i) reach - the adult population has 100% mobile phone ownership and 92% internet national coverage…
- Conditions
- Cardiovascular Diseases, Cerebral Infarction, Type2 Diabetes Mellitus, Hypertension,Essential
- Trial name
- SELECT (NCT04082091)
- Testing
- SELECT mHealth Program
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Cerebral Infarction
BRUSH Sign: Radiolographic Marker of Cerebral Infarctus Prognosis
Today the treatment of ischemic stroke in acute phase is based on medicinal or endovascular revascularization. Cerebral MRI sequences help the diagnostic. This procedure uses deoxyhemoglobin as an endogenous tracer.
- Trial name
- NCT03467269
- Testing
- Brush sign
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Aortic Stenosis, Brain Infarction
Neuroprotection in Patients Undergoing Aortic Valve Replacement
To evaluate the efficacy and safety of embolic protection devices to reduce ischemic brain injury in patients undergoing surgical aortic valve replacement (AVR).
- Conditions
- Aortic Stenosis, Brain Infarction, Cerebrovascular Accident, Stroke
- Trial name
- NCT02389894
- Testing
- Embol-X Embolic Protection Device, CardioGard Cannula
- Where
- 18 sites in United States, Canada
- Volunteers
- 383 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cerebral Infarction
Contrast Enhanced Ultrasound of Carotid Plaque in Acute Ischemic Stroke
This is a biomedical, single-center, and prospective study of a consecutive patients cohort in acute ischemic stroke with carotid plaque.
- Trial name
- CUSCAS (NCT03115242)
- Testing
- Contrast injection Sonovue®
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Versailles Hospital
Intracranial Pressure Increase
Posterior Fossa Intracranial Pressure (ICP) Measurement: Clinical Study
In modern medicine, doctors attempt to monitor all physiological variables to assess their evolution and to decide, based on their changes, the therapeutic attitudes to adopt.
- Trial name
- Postfossa ICP (NCT04675216)
- Testing
- Posterior fossa intracranial pressure measurement
- Where
- 2 sites in Spain
- Volunteers
- 12 people
- Sponsor
- University of Valencia
Cerebral Infarction
Chinese Assessment for Vinpocetine In Neurology
Trial Title：The treatment of Vinpocetine（Cavinton）in patients with cerebral infarction, an open, randomized, multi-center control study 1.
- Trial name
- CAVIN (NCT01400035)
- Where
- China
- Volunteers
- 610 people
- Sponsor
- Shanghai Rxmidas Pharmaceuticals Co. Ltd.
Atherosclerosis
Progression of Early Subclinical Atherosclerosis
The overall objective of this study is to characterize the prevalence and progression rate of subclinical atherosclerotic lesions and to study their association to the imaging characteristics of atheroma plaques and to the…
- Trial name
- PESA (NCT01410318)
- Where
- Spain
- Volunteers
- 4,184 people, healthy volunteers welcome
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Coronary Disease, Cardiovascular Diseases
Molecular Epidemiology of Myocardial Infarction and Stroke in Older Adults - Ancillary to CHS
To investigation the association of thrombosis and inflammation genes with sub-clinical cardiovascular disease and with incident myocardial infarction and stroke in older adults.
- Conditions
- Coronary Disease, Cardiovascular Diseases, Heart Diseases, Cerebrovascular Accident
- Trial name
- NCT00078429
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Stroke, Cerebrovascular Disorders
The Technology-assisted, High Intensive, Task-oriented Exercise Trial
The interventional study aims to increase the knowledge on arm and hand rehabilitation after stroke within community-based services.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases
- Trial name
- TECHITO (NCT03396939)
- Testing
- Orthosis
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Acute Ischemic Stroke
Infarct Growth After Intravenous Tocilizumab in Adults With Acute Ischemic Stroke Undergoing Endovascular Thrombectomy - ILLUMINATE
The goal of this phase II, placebo-controlled intervention study is to investigate whether tocilizumab, an interleukin-6 (IL-6) receptor inhibitor, may have a neuroprotective effect by reducing infarct growth in adults with acute…
- Trial name
- Illuminate (NCT07870681)
- Testing
- Tociliuzumab
- Where
- 6 sites in Denmark, Norway
- Volunteers
- 156 people
- Sponsor
- Oslo University Hospital
Cerebral Infarction
The Metabolism Research of KLK Treating Acute Cerebral Ischemic Stroke: Focus on Drug Frequency-Efficacy Relationship
Evaluate the effectiveness of the of kallikrein in the different drug frequency for acute anterior circulation cerebral infarction.
- Trial name
- MAISKFE (NCT02806128)
- Testing
- Human Urinary Kallidinogenase for Injection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Huisheng Chen
Cardiovascular Diseases, Cerebrovascular Accident
Homocyst(e)Ine, Vitamin Status, and CVD Risk
To test the hypotheses that the risk of myocardial infarction and/or stroke is associated with elevated plasma levels of homocysteine, and low plasma levels of folate, vitamins B12 and B6.
- Conditions
- Cardiovascular Diseases, Cerebrovascular Accident, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005482
- Sponsor
- University of Washington