Clinical trials: Brain Fog
Premenstrual Syndrome, Premenstrual Dysphoric Disorder
CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life
This study evaluates the feasibility and efficacy of the Samphire Guided Care (SGC) program a 12-week structured digital health program combining clinician-led onboarding, at-home neuromodulation using the Lutea tDCS device…
- Conditions
- Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Dysmenorrhea, Endometriosis
- Trial name
- CREST (NCT07679074)
- Testing
- Lutea Transcranial Direct Current Stimulation (tDCS) Device, Samphire Guided Care Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samphire Group, Inc.
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration Outdoors
This study aims to examine whether listening to natural sounds in a noisy outdoor environment compared to no natural sounds influences behavioural, cognitive, affective, and physiological markers.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- NEO (NCT05679882)
- Testing
- Masking Sounds, No Masking Sounds
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Post COVID-19, Cognitive Dysfunction
Multimodal Investigation of Post COVID-19 in Females
The purpose of this study is to investigate the effects of transcutaneous vagus nerve stimulation (t-VNS) on Long Covid symptoms in females and to identify factors influencing susceptibility and recovery-particularly in the…
- Trial name
- NCT05225220
- Testing
- Parasym Device (of Parasym Ltd, UK) using Transcutaneous Vagus Nerve Stimulation (t-VNS)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Neoplasm, Colorectal, Cognitive Impairment
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute.
- Conditions
- Neoplasm, Colorectal, Cognitive Impairment, Cognitive Dysfunction, Cognitive Change
- Trial name
- Chemo Brain (NCT05014399)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Joseph McCollom
Mental Fatigue, Near Infrared Spectroscopy
The Effect of Mental Fatigue on the Cerebral Oxygenation During Endurance Exercise
The experiment will consist of 3 consecutive trials performed in a sound-insulated climate chamber (20°C and 40% RH) at the VUB. Participants will be asked to return 3 successive weeks.
- Conditions
- Mental Fatigue, Near Infrared Spectroscopy, NIRS, Condition
- Trial name
- NCT05355493
- Testing
- Time to Exhaustion cycling test, Go/NoGo task
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Noisy Environment
This study aims to examine whether listening to natural sounds in a noisy (traffic) environment compared to traffic noise only impacts behavioural, cognitive, affective, and physiological markers associated with attention…
- Conditions
- Cognitive Fatigue, Mental Fatigue, Heart Rate Variability, Skin Conductance
- Trial name
- EARS (NCT05009784)
- Testing
- Baseline, Fatigue Manipulation, Traffic Sound
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Alert Fatigue, Health Personnel
Study to Evaluate Efficacy of EnXtra on Accuracy & Reaction Time, Perceived Alertness & Digital Fatigue for Video Gamers
In the present study, Sponsor aim to evaluate the effects of EnXtra® as to improve Accuracy \& Reaction Time, Perceived Alertness \& Digital Fatigue for Video Gamers.
- Trial name
- NCT05586880
- Testing
- Experimental: EnXtra 300 mg/ capsule, Microcrystalline cellulose (MCC) 300mg
- Where
- 2 sites in India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Reduction of Empathy-Based Stress in Healthcare Staff
Compassion Project: Developing an Empathy-Based Stress Intervention
Compassion is recognising that someone is suffering and wanting to help them. Compassion fatigue is a reduction in capacity to feel compassion for others.
- Trial name
- NCT06343818
- Testing
- The Compassion Project: Intervention to Reduce Empathy-Based Stress in Staff
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bath
Cognitive Fatigue, Mental Fatigue
Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance
This study aims to examine the effects of cognitive fatigue on heart rate variability and skin conductance and develop a machine learning model.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- FRESH (NCT05011318)
- Testing
- Baseline, Fatigue Manipulation
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Muscle Fatigue, Mental Fatigue
The Influence of Fatigue on Trunk Motor Control and Brain Activity
This study aims at examining the influence of both physically and cognitively induced fatigue on trunk motor control on the one hand and brain activity related to movement preparation on the other hand, in healthy adult subjects.
- Conditions
- Muscle Fatigue, Mental Fatigue, Event-related Potentials
- Trial name
- NCT03576391
- Testing
- Control condition, Rapid Arm Movements, Physical fatigue condition
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Ghent
Mental Fatigue, Recovery
Effects of Different Nap Durations on Volleyball Performance and EEG Activity Following Mental Fatigue
Mental fatigue is known to impair cognitive and physical performance in athletes, but the effectiveness of different nap durations in counteracting these effects remains unclear.
- Conditions
- Mental Fatigue, Recovery, Volleyball, Sport Performance
- Trial name
- MFNAP (NCT07700576)
- Testing
- Mental Fatigue Induction, Control Condition, Daytime Nap 20 Minutes
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Inonu University
Laughter Yoga
The Effect of Laughter Yoga on the Secondary Traumatic Stress Level and Psychological Well-Being of Midwives
Aim: The aim of this study is to determine the effect of laughter yoga, which includes various relaxing practices, on secondary trauma levels and psychological well-being of midwives.
- Trial name
- NCT05933915
- Testing
- group-based laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Burnout, Professional, Anxiety
Storytelling Through Music to Improve Well-being Among Homeless Service Providers
Homelessness is a complex social issue and requires a dedicated workforce of helping professionals, including nurses and social workers.
- Conditions
- Burnout, Professional, Anxiety, Depression, Secondary Trauma
- Trial name
- NCT06536387
- Testing
- Storytelling Through Music
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Healthy Adults
The Effect of Different Physical Activity Strategy on Cognitive Efficiency and Mental Fatigue Resistance
The main aim of this biomedical study is to determine the effect of moderate-intensity aerobic exercise, before and after an 8-hour workday and a combined work model, on the performance and efficiency of cognitive functions…
- Trial name
- NCT07130825
- Testing
- 8 hours simulated mental workday, Moderate intensity aerobic activity, Combined work model
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Parkinson's Disease
Electrical Stimulation for the Relief of Freezing of Gait (FOG) in Parkinson's Patients
Potential for electrical stimulation to ameliorate Freezing of Gait (FOG)
- Trial name
- NCT01970891
- Testing
- neuromuscular stimulation device
- Where
- Ireland
- Volunteers
- 12 people
- Sponsor
- National University of Ireland, Galway, Ireland
Hearing Loss, Tinnitus
Hearing Impairment, Cognitive Therapy and Coping
A randomized controlled study with hearing impaired workers, who have voluntarily signed up for an 8 session cognitive therapy (CBT) course The CBT intervention will be compared to a waiting list control group.
- Conditions
- Hearing Loss, Tinnitus, Stress, Psychological, Mental Fatigue
- Trial name
- NCT01206829
- Testing
- 8-session CBTcourse, 8 session cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Oslo University Hospital
ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis
ME/CFS Brain Fog: Cognitive Rehabilitation Trial
The purpose of this study is to compare two approaches to cognitive rehabilitation in adults with post-viral cognitive syndrome, which resulted in brain fog.
- Conditions
- ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19, Chronic Fatigue
- Trial name
- NCT07523113
- Testing
- Processing Speed Training, In-session Instrumental Activities of Daily Living Training, Transfer Package
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Freezing of Gait, Parkinson Disease
Percept Transitions in FOG and PD
The purpose of this research is to examine the possible causes and signs of freezing of gait (FOG) secondary to Parkinson's disease (PD).
- Trial name
- NCT06848205
- Testing
- OFF Parkinson's Medication(s), OFF Deep Brain Stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Compassion Fatigue, Resilience
Interprofessional Group Intervention to Enhance Compassion Satisfaction and Resilience
The purpose of this study is to evaluate an educational professional development program designed to assist health care professionals in developing self-awareness and self-care choices as a means to avoid compassion fatigue and…
- Trial name
- CSRS (NCT04888000)
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- OSF Healthcare System
Menopause
A Cognitive Intervention to Manage 'Brain Fog' in Menopause Transition: Feasibility Study
Cognitive complaints at menopause transition (MT), often described as 'brain fog'; can include difficulty recalling words and numbers, misplacing items, trouble concentrating and forgetfulness.
- Trial name
- NCT06940466
- Testing
- Online cognitive intervention
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University College, London