Clinical trials: Brain Aneurysm
Ischemic Heart Disease, Cardiac Arrest
Registry of Multicenter Brain-Heart Comorbidity in China
This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program.
- Conditions
- Ischemic Heart Disease, Cardiac Arrest, Atrial Fibrillation, Heart Failure
- Trial name
- BHC-C (NCT05961748)
- Testing
- Multi-disciplinary assessment
- Where
- 14 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Beijing Tiantan Hospital
Subarachnoid Hemorrhage
Evaluate the Use of Glibenclamide on Acute aSAH
A randomized, open-labeled, blank-controlled and prospective trial meant to evaluate the use of glibenclamide on acute aneurysmatic subarachnoid hemorrhage.
- Trial name
- NCT05137678
- Testing
- glibenclamide
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Aneurysm
Tubridge Flow Diverter Study For Intracranial Aneurysms
The scope of this trial is the collection and analysis of the important safety outcomes in the real world, related to the use of the Tubridge flow diverter in the treatment of intracranial aneurysms.
- Trial name
- TRACE-IA (NCT05646108)
- Testing
- Endovascular treatment
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- MicroPort NeuroTech Co., Ltd.
Aortic Aneurysm, Aortic Dissection
Freestyle Prosthesis for Aortic Root-replacement With and Without Hemiarch Replacement
The Freestyle® prosthesis (Medtronic plc, Dublin, Ireland) is a biological, porcine aortic root implanted in various combinations and techniques since the 1990s.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Endocarditis, Root Abscess
- Trial name
- NCT04068337
- Testing
- Aortic root replacement with Freestyle biological prosthesis with and without hemiarch replacement
- Where
- Switzerland
- Volunteers
- 278 people
- Sponsor
- Triemli Hospital
Intracranial Aneurysm
FRED Retrospective Study of Intracranial Aneurysms Treatment
To evaluate the long-term safety and efficacy of Flow Re-Direction Endoluminal Device System (FRED) in the treatment of intracranial aneurysms in the post-market environment
- Trial name
- FRED (NCT06982781)
- Testing
- Flow Re-Direction Endoluminal Device System(FRED)
- Volunteers
- 2,000 people
- Sponsor
- Microvention-Terumo, Inc.
Aortic Aneurysm, Aortic Dissection
Clinical Investigation of Clinical Safety and Performance of the SP-GRIPFLOW, Selective Cerebral Perfusion Catheter When Used for Cerebral Perfusion During Aortic Arch Repair
The purpose of this study is to determine if the SP-GRIPFLOW catheter (the catheter designed by Fuji Systems) is safe and how well it functions.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Aortic Arch Aneurysm, Aortic Arch; Aneurysm, Dissecting
- Trial name
- NCT05421130
- Testing
- Selective Cerebral Perfusion Catheter
- Where
- 5 sites in Germany, Netherlands
- Volunteers
- 149 people
- Sponsor
- Fuji Systems Corporation
Cerebral Aneurysm, Trigeminal Neuralgia
EEG Monitoring to Assess Emergence From Neuroanesthesia
A highly desired result in neuroanesthesia is a prompt, controlled emergence following a neurosurgical procedure. Considerable strides have been made in this direction with volatile anesthetic agents such as sevoflurane or…
- Trial name
- NCT00443807
- Testing
- On-line EEG monitoring during neurosurgery, EEGo vs BIS
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Manitoba
Flow Diverter
Clinical Safety and Efficacy of Flow-diverter in the Treatment of Intracranial Aneurysms
To collect the safety and effectiveness data of flow-di in the treatment of intracranial aneurysms in real-world clinical practice, verify its classification of treatment strategies for aneurysms of different locations and…
- Trial name
- NCT06943729
- Where
- China
- Volunteers
- 523 people
- Sponsor
- Huashan Hospital
Intracranial Aneurysm, Brain Arterial Disease
Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform
BALT has designed an electronic platform to continue collecting clinical data as part of the post-marketing clinical follow-up of its devices.
- Conditions
- Intracranial Aneurysm, Brain Arterial Disease, Acute Ischemic Stroke, Peripheral Vascular Diseases
- Trial name
- EVIDENCE (NCT04927156)
- Testing
- BALT medical devices
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 10,000 people
- Sponsor
- Balt Extrusion
Intracranial Aneurysm
Pipeline for Uncoilable or Failed Aneurysms
To determine the safety and effectiveness of Pipeline Embolization Device for the treatment of uncoilable or failed wide-necked intracranial aneurysms (IA).
- Trial name
- PUFS (NCT00777088)
- Testing
- Pipeline Embolization Device (PED)
- Where
- 10 sites in United States, Hungary and 1 more
- Volunteers
- 108 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Intracranial Aneurysms, Ruptured Aneurysm
Impact of Platelet Activation in Intracranial Aneurysm Rupture Risk - PLAQRAN
Sub arachnoid hemorrhage consecutive to intracranial aneurysm rupture is a devastating disease. Predictors of intracranial aneurysm rupture are limited and focus mainly on size and location.
- Trial name
- PLAQRAN (NCT03408379)
- Testing
- Collection of blood sample in aneurysm
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Social Determinant of Health, Intracranial Aneurysms
Risk Analysis of Intracranial Aneurysm Rupture Through Social Determinants of Health
Intracranial aneurysms (IA) are arterial malformations affecting about 3% of the overall population. Rupture is the most severe complication, as it is associated with nearly 30% of death or severe disability.
- Conditions
- Social Determinant of Health, Intracranial Aneurysms, Subarachnoid Hemorrhage, Treatment Outcomes
- Trial name
- ARAMISS (NCT06866210)
- Where
- France
- Volunteers
- 1,800 people
- Sponsor
- Nantes University Hospital
Intracranial Aneurysm
Reduction of Microembolism After the Intervention Surgery of Intracranial Aneurysms by Administration of Tirofiban
The goal of this clinical trial is to investigate whether intravenous injection of tilofiban can reduce microembolism in patients with unruptured intracranial aneurysms after Stent-Assisted Coil Embolization.The main questions it…
- Trial name
- NCT05841147
- Testing
- Tirofiban, normal saline
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Lu Hua
Unruptured Cerebral Aneurysm, Hemifacial Spasm
Effect of Acupuncture on Inflammation and Immune Function After Craniotomy
The aim of this study is to evaluate the effect of acupuncture on inflammation and immune function after craniotomy. This study will be a single-center, parallel group clinical trial that will be conducted at Kyung Hee University…
- Conditions
- Unruptured Cerebral Aneurysm, Hemifacial Spasm, Brain Tumor
- Trial name
- NCT02761096
- Testing
- acupuncture, conventional treatment
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Kyunghee University Medical Center
Aneurysm, Intracranial, Carotid-Cavernous Sinus Fistula
New Covered Stent (Willis) for the Endovascular Reconstruction of Intracranial Vessel Wall Defects Registry
The purpose of this study is to evaluate the effectiveness, long-term safety and explore the safety and efficacy factors WILLIS™ intracranial stent graft system in clinical applications.
- Trial name
- COVER (NCT02820779)
- Testing
- WILLIS
- Where
- 11 sites in China
- Volunteers
- 100 people
- Sponsor
- Xuanwu Hospital, Beijing
Intracranial Aneurysm
Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device
The purpose of this study is to demonstrate effectiveness and safety of the CODMAN ENTERPRISE® Vascular Reconstruction Device and Delivery System.
- Trial name
- NCT02532517
- Testing
- CODMAN ENTERPRISE® Vascular Reconstruction Device and Delivery System
- Where
- 11 sites in United States
- Volunteers
- 45 people
- Sponsor
- Cerenovus, Part of DePuy Synthes Products, Inc.