Clinical trials: Brain Activity
Stroke, Sensory Defect
The Effect of ıntensified Sensory-based Therapy on Upper Extremity Functions and Activities of Daily Living
Sensory dysfunction following stroke is a common condition. The deficiency in the somatosensory system negatively affects the learning of new motor skills by preventing feedback from the sensory system, and it can also cause…
- Trial name
- NCT05133219
- Testing
- Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kocaeli University
Eating Disorders, Anorexia Nervosa
Appetite-Related Brain Activity in Women With Anorexia Nervosa
This study will use functional magnetic resonance imaging to compare appetite-related brain activity in women with anorexia nervosa before and after receiving treatment for the disorder.
- Trial name
- NCT00344656
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Hemiplegic Cerebral Palsy With Spasticity (Diagnosis)
A Comparative Analysis on Physical Activity Performance and Motor Function of Affected Upper Extremity Before and After a CIMT Program in Young Children With Hemiparetic Cerebral Palsy
This study evaluates CIMT(Constraint Induced Movement Therapy) in the treatment of physical activity performance and motor function of the weaker extremity in young children with cerebral palsy.
- Trial name
- NCT03418519
- Testing
- Constraint Induced Movement Therapy
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Cerebral Palsy, Spastic
Individualized Virtual Reality in the Upper Extremity Rehabilitation of Hemiparetic Cerebral Palsy
This study aimed to investigate the effect of individualized virtual reality therapy on upper extremity functions of children with hemiparetic cerebral palsy.
- Trial name
- NCT04630678
- Testing
- Virtual Reality Therapy, Conventional Physiotherapy, Activity Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Cerebral Palsy
Diet and Activity in Cerebral Palsy
This study aims to fill a gap in the literature, identify relevant clinical measures, and provide insight into the independent modifiable risk factors of obesity in the CP population with the long-term goal of improving…
- Trial name
- NCT02175108
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Activities of Daily Living
Self-supporting Care Model in Home Environment for Patients With Stroke
The purpose of this study was to administer intervention based on self-supporting care model in home environment and to explore the effects of this intervention on stroke patients' activities of daily living, movement, cognition…
- Trial name
- NCT04744324
- Testing
- Self-supporting Care, Home health education
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Stroke
High Intensity Interval Training in Chronic Stroke Patients
Stroke is a global health-care problem that is common, serious and disabling. In most countries, stroke is second or third most common cause of death and one of the main causes of acquired adult disability.
- Trial name
- NCT01777113
- Testing
- High intensity aerobic training, High Intensity Strength Training, Mixed Training
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Universita di Verona
Alzheimer Disease, Physical Activity
Inspiring Seniors Towards Exercise Promotion to Protect Cognition
The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints.
- Trial name
- iSTEP+ (NCT06496425)
- Testing
- Beat-accentuated, personalized music stimulation (BMS), Strength Training (ST), Aerobic exercise (AE)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emory University
Brain Health Activities, Cognition
Psychological and Lifestyle Factors That Predict Adherence of Multi-domain Interventions for Promoting Brain Health
Ageing is associated with a rising burden of neurological disorders, particularly dementia, which are now the leading cause of disability worldwide.
- Conditions
- Brain Health Activities, Cognition, Prevention, Cognitive Decline
- Trial name
- ToBrainHealth (NCT07387523)
- Testing
- Generic Lifestyle Education, ToBrainHealth Personalised Digital Intervention, ToBrainHealth Personalised Digital Intervention with Coaching
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut Guttmann
Alzheimer's Disease
Statins in Cerebral Blood Flow and Neuronal Activity--A Pilot Study
Specific Aim: Demonstrate that statins have an effect on cerebral blood flow and neuronal activity
- Trial name
- NCT03411291
- Testing
- MRI, MR Spectroscopy, MR Perfusion
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Cedars-Sinai Medical Center
Stroke
Efficacy of Task-specific Training on Physical Activity Levels Post-stroke
The majority of people after stroke demonstrate mobility limitations, which may reduce their physical activity levels. Task-specific training has shown to be an effective intervention to improve mobility in individuals with…
- Trial name
- NCT02937480
- Testing
- Task-specific training, Global stretching, memory exercises, health care orientation
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Federal University of Minas Gerais
Stroke, Cerebrovascular Accident
Fluoxetine Opens Window to Improve Motor Recovery After Stroke
The FLOW trial is a randomized placebo-controlled trial analyzing the effect of coupling an anti-depressant, fluoxetine (Prozac), and exercise to improve motor recovery following a stroke.
- Conditions
- Stroke, Cerebrovascular Accident, Cerebral Infarction, Brain Infarction
- Trial name
- FLOW (NCT03448159)
- Testing
- Fluoxetine Hydrochloride, Exercise Program
- Where
- 8 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Parkinson's Disease
Subthalamic Nucleus, Akinesia and Parkinson's Disease
This program aims to understand the role of the subthalamic nucleus in the control of the movement in healthy humans and patients with Parkinson's disease, how the STN dysfunction contributes to akinesia and how the STN…
- Trial name
- GB-MOV (NCT01682668)
- Testing
- Bilateral subthalamic stimulation
- Where
- 2 sites in France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Depression
Brain Activity Changes and Treatment Response in Depressed People Who Are Receiving Antidepressant Medication
This study will examine how brain activity is affected by antidepressant treatment and how changes in brain activity relate to treatment response in people with depression.
- Trial name
- NCT00375843
- Testing
- Escitalopram, Sertraline
- Where
- 3 sites in United States
- Volunteers
- 118 people
- Sponsor
- National Institute of Mental Health (NIMH)
Cognitive Frailty
Chair Exercise and Intergenerational Activities in Older Adults With Physio-Cognitive Decline Syndrome
The goal of this clinical trial is to investigate the effects of chair exercise followed by intergenerational activity in frailty syndrome and changes in serum mBDN levels among older adults with Physio-Cognitive Decline Syndrome…
- Trial name
- PCDS (NCT07335978)
- Testing
- Intervention 1
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Atma Jaya Catholic University of Indonesia
Intracerebral Hemorrhage
Improving Platelet Activity for Cerebral Hemorrhage Treatment - DDAVP Proof of Concept
The investigators intend to show that DDAVP improves platelet activity from baseline to 60 minutes after treatment start.
- Trial name
- IMPACT (NCT00961532)
- Testing
- DDAVP injection (desmopressin acetate)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Northwestern University
Concussion, Brain, Concussion, Mild
Mobile Subthreshold Exercise Program for Concussion--R01
Approximately 1.9 million youth sustain a concussion each year, and up to 30% experience persistent post-concussive symptoms (PPCS) such as headache, dizziness, and difficulty focusing that continue for weeks or months.
- Conditions
- Concussion, Brain, Concussion, Mild, Brain Injuries, Traumatic, Persistent Post Traumatic Headache
- Trial name
- MSTEP-R01 (NCT04688255)
- Testing
- MSTEP, Stretching
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Seattle Children's Hospital
Dynapenia, Abdominal Obesity
Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life.
- Trial name
- NCT07180485
- Testing
- whole body vibration training, control group
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital
Cognitive Performance
Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training
The overall objective is to identify the cognitive circuits associated with military aviator performance by analyzing what anatomic regions of the brain are functionally "active" (neuronal circuit) while being performing virtual…
- Trial name
- fMRI Pilots (NCT06606925)
- Testing
- fMRI with virtual reality flight simulator
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- The Geneva Foundation
Obsessive Compulsive Disorder
Modification of Cerebral Activity of Obsessive Compulsive Disorder (OCD) Patients During Cognitive and Behavioral Therapy
Obsessive compulsive Disorder (OCD) is a frequent psychiatric disorder. Obsessions and compulsions are the two manifestations of this disease.
- Trial name
- TOC TOC (NCT01331876)
- Testing
- Cognitive and behavioral Therapy
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France