Clinical trials: Brachial Plexus Injury, open to volunteers
Tetraplegia, Spinal Cord Injury
Cortical Recording and Stimulating Array Brain-Machine Interface
The purpose of this research study is to demonstrate the safety and efficacy of using two CRS Arrays (microelectrodes) for long-term recording of brain motor cortex activity and microstimulation of brain sensory cortex.
- Conditions
- Tetraplegia, Spinal Cord Injury, Brainstem Stroke, Brachial Plexus Injury
- Trial name
- CRS-BMI (NCT01894802)
- Testing
- Implantation of CRS Arrays
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Michael Boninger
Brachial Plexus Birth Palsy
Constraint Therapy for Brachial Plexus Birth Injury
The goal of this clinical trail is to learn if constraint physical therapy is a better treatment than normal physical therapy for infants with a brachial plexus birth injury.
- Trial name
- CRIB (NCT07868029)
- Testing
- Constraint Therapy
- Volunteers
- 30 people
- Sponsor
- Boston Children's Hospital
Obstetrical Brachial Plexus Palsy
Effectiveness and Safety of Early Intramuscular Botulinum Toxin Injections to Prevent Shoulder Deformity in Babies With Obstetrical Brachial Plexus Palsy
In children population with obstetrical brachial plexus palsy (OBPP), shoulder musculoskeletal deformity is the main cause of morbidity, with a loss of range of shoulder motion, pain and a reduction in social participation.
- Trial name
- POPB-TOX (NCT03198702)
- Testing
- Botulinum toxin type A injection
- Where
- 7 sites in France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Brest
Obstetric Brachial Plexus Injury
Sensory Integration Therapy in Children With Congenital Brachial Plexus Injury: Developmental Outcomes
The purpose of this study is to investigate the effectiveness of sensory integration therapy in reducing sensory, motor, and cognitive developmental impairments following Congenital Brachial Plexus Injury (CBPI), and to support…
- Trial name
- SI-BPI (NCT07134049)
- Testing
- sensory integration therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Obstetric Brachial Plexus Palsy
Development of Diffusion MRI and Tractography Technique for the Detection of Nerve Lesions in Brachial Plexus Injuries
The objective of this prospective study is to contribute to improving the management of patients with obstetric brachial plexus palsy.
- Trial name
- IRM-POPB (NCT07767708)
- Testing
- Performing an MRI
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Brachial Plexus Injury
Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury
The purpose of this study is to see how much pain intensity is affected by high frequency spinal cord stimulation therapy in individuals with serious brachial plexus injury.
- Trial name
- NCT04733599
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Brachial Plexus Birth Palsy, Brachial Plexus Palsy
Evaluation of Pain, Upper Extremity Function, and Social Appearance Anxiety in Adults With Obstetric Brachial Plexus Palsy Who Underwent Shoulder Tendon Transfer Surgery
This observational study aims to evaluate pain and upper extremity function in adults with obstetric brachial plexus palsy who underwent shoulder tendon transfer surgery using the Modified Hoffer technique during childhood.
- Conditions
- Brachial Plexus Birth Palsy, Brachial Plexus Palsy, Brachial Plexus Palsy Due to Birth Trauma
- Trial name
- NCT07655271
- Testing
- Clinical Assessment Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Hand Injuries and Disorders, Wrist Sprain
Perineural vs Intravenous Dexamethasone as an Adjuvant to Brachial Plexus Block in Pediatric Hand Surgery
This clinical trial will evaluate the neurological safety and analgesic effectiveness of dexamethasone administered perineurally or intravenously as an adjuvant to brachial plexus block in children undergoing hand or forearm…
- Trial name
- NCT07474909
- Testing
- iv dexamethasone, pn dexamethasone, 0.9%NaCl
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Poznan University of Medical Sciences
Upper Limb Deficits
Assessment of Feasibility, Functionality and Usability of an Hybrid Assistive Exoskeleton for Upper Limb
People affected by stroke or brachial plexus injuries experience huge impairment in using upper limbs for everyday life activities.
- Trial name
- NCT07000279
- Testing
- Assistive exoskeleton for activities of daily living (ADLs), Assistive exoskeleton for box and block, Assistive exoskeleton for maximum reaching height
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Glenohumeral Subluxation, Neonatal Brachial Plexus Palsy
Investigation of the Relationship Between Shoulder Alpha Angle and Humeral Head Displacement Percentage Measured by Ultrasonography in Neonatal Brachial Plexus Palsy Infants With Clinical Parameters
This study will examine infants with a birth-related nerve injury called neonatal brachial plexus palsy, which can affect movement in the arm and sometimes cause the shoulder joint to shift out of its normal position…
- Conditions
- Glenohumeral Subluxation, Neonatal Brachial Plexus Palsy, Brachial Plexus Injuries
- Trial name
- NCT07768904
- Testing
- Shoulder Ultrasonography, Standardized Clinical Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Brachial Plexus Birth Palsy, Brachial Plexus Palsy
Validity and Reliability of the Turkish Version of the Impact of Brachial Plexus Injury Questionnaire (IMBPIQ)
The aim of this methodological study is to translate the Impact of Brachial Plexus Injury Questionnaire (IMBPIQ) into Turkish, culturally adapt it, and evaluate its validity and reliability for use in adults with brachial plexus…
- Conditions
- Brachial Plexus Birth Palsy, Brachial Plexus Palsy, Brachial Plexus Palsy Due to Birth Trauma, Obstetric Brachial Plexus Injury
- Trial name
- NCT07654504
- Testing
- Questionnaire Assessment Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Diaphragmatic Function, Metacarpal Fracture
Evaluation of Diaphragmatic Function After Interscalene Block With Liposomal Bupivacaine
The study aims to evaluation the effects of Liposomal Bupivacaine on diaphragmatic function in patients undergoing upper limb surgery who receive Interscalene Brachial Plexus Block.
- Conditions
- Diaphragmatic Function, Metacarpal Fracture, Radius Fracture, Peripheral Nerve Neurolysis
- Trial name
- NCT07263295
- Testing
- 0.5% Hydrochloride Bupivacaine 20ml, 0.5% Hydrochloride Bupivacaine 10ml, Liposomal Bupivacaine 10mL
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhejiang University
Shoulder Surgery, Shoulder Pain
Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
This prospective observational study aims to evaluate the incidence of hemidiaphragmatic paralysis in patients receiving interscalene brachial plexus nerve block with prolonged neural blockade.
- Conditions
- Shoulder Surgery, Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
- Trial name
- NCT04209504
- Testing
- Ultrasound, Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Brachial Plexus Birth Palsy, Erbs Palsy
Pilot Test of Caregiver Training Protocol for Brachial Plexus Birth Injury
The brachial plexus is a network of nerves that exit the spinal cord from the C5-T1 nerve roots and provide all motor and sensory function to the arm from the shoulder to the fingers.
- Trial name
- CTP-BPBI (NCT06623357)
- Testing
- Pilot Training Protocol, Standard Training Protocol
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Brachial Plexus Injury
Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries
The purpose of this study is to assess pre- and postoperative neuropathic pain in patients with traumatic brachial plexus injuries to determine if intraoperative ketamine infusion affect neuropathic pain associated with avulsion…
- Trial name
- NCT04933149
- Testing
- Ketamine Infustion
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Brachial Plexus Birth Palsy, Physical Therapy
Virtual Reality and Dual-Task Training for Cortical Plasticity in Children With Brachial Plexus Injury
Brachial plexus birth injury (BPBI) is a condition that occurs when the nerves controlling the arm are injured during birth, leading to weakness, limited movement, and sensory problems.
- Trial name
- NCT07291310
- Testing
- Conventional Physiotherapy Program, Virtual Reality, Dual Task
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Istanbul Aydın University