Clinical trials: Borderline Personality Disorder (BPD)
Borderline Personality Disorder (BPD), Avoidant Personality Disorders
Physical Activity in the Management of Personality Disorders
The PANDA trial is studying whether two types of physical activity - a walking program and supervised karate training - are safe, acceptable, and possible for adults with certain personality disorders.
- Trial name
- PANDA (NCT07341438)
- Testing
- Karate, Pedometer-based walking, Treatment as usual (TAU)
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Julie Midtgaard
Borderline Personality Disorder (BPD)
Brief Psychological Intervention for Suicidal Patients With Borderline Personality Disorder in the Emergency Department
When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour.
- Trial name
- NCT06675461
- Testing
- Gold Card Intervention, Treatment as usual
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- Centre for Addiction and Mental Health
Borderline Personality Disorder
Cognitive Reappraisal Training for Borderline Personality
Previous work by the study group convinced the study team to pursue development of focused cognitive reappraisal training as a novel approach to treatment of BPD, either as stand-alone treatment or in concert with evidence-based…
- Trial name
- BPD (NCT04967222)
- Testing
- Cognitive Reappraisal by Distancing, Control Downregulate Condition
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Borderline Personality Disorder
Cognitive Control of Negative Stimuli in BPD
Borderline personality disorder (BPD) is characterized by impairments in the cognitive control of negative information. These impairments in cognitive control are presumably due to blunted activity of the dorsolateral prefrontal…
- Trial name
- NCT03636139
- Testing
- transcranial DC stimulation : anodal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
Heavy MHS Use, General Psychopathology
Efficacy of Time-limited Psychodynamic Psychotherapy and Informed Clinical Management in BPD High MHS Users
Subjects affected with severe Borderline Personality Disorder (BPD) are often heavy users of Mental Health Services (MHS). This study evaluates the efficacy of the addition of Sequential Brief Adlerian Psychodynamic Psychotherapy…
- Conditions
- Heavy MHS Use, General Psychopathology, Working Alliance
- Trial name
- HUMSH (NCT01356069)
- Testing
- SB-APP, treatment as usual
- Volunteers
- 35 people
- Sponsor
- University of Turin, Italy
Borderline Personality Disorders, BPD
DBT Skills Expanded With Contextual Intervention for Long Lasting Symptoms in Borderline Personality Disorder
Although borderline personality disorder (BPD) tend to the clinical remission in long-term follow-up studies, a significant subgroup of patients continues to present long lasting symptoms such as low mood, emptiness and…
- Trial name
- DBT+Context (NCT05972096)
- Testing
- Combination DBT, self-compassion and contextual-based skills
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD)
Implementing a Therapy for Complex Trauma in French-Speaking Settings
Many individuals living with borderline personality disorder (BPD) have experienced childhood trauma, such as abuse or neglect. A significant number of them also meet the criteria for post-traumatic stress disorder (PTSD).
- Conditions
- Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- TRAUL (NCT07123974)
- Testing
- Dialectical Behaviour Therapy for Post-Traumatic Stress Disorder (DBT-PTSD)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Borderline Personality Disorder
MBT in Groups for Adolescents With BPD or Subthreshold BPD Versus TAU - the M-GAB Randomized Controlled Trial
Background: Although it is now possible to diagnose Borderline Personality Disorder (BPD) in adolescents younger than 18 years according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-V), and…
- Trial name
- M-GAB (NCT02068326)
- Testing
- Mentalization Based Treatment, Treatment As Usual
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Symptom Assessment in Adolescents Placed on Child Welfare
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- PePsAdoTND (NCT07794332)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Borderline Personality Disorder, Major Depressive Disorder
Psilocybin in Co-occuring Major Depressive Disorder and Borderline Personality Disorder
The primary objective of the study is to evaluate the safety and efficacy of psilocybin in adults with major depressive disorder (MDD) and borderline personality disorder (BPD).
- Trial name
- NCT05399498
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Chicago
Borderline Personality Disorder (BPD)
The Effectiveness of Dialectical Behavioral Group Psychotherapy Compared to Supportive Individual Psychotherapy In Patients With Borderline Personality Disorder: A Study on Therapeutic Alliance, Depression, Cognitive Function, Impulsivity, Suicide Risk, BDNF Levels, NFkB Levels, SOD Levels
In the context of therapy for Borderline Personality Disorder, our department had conduct a study titled "The Effectiveness of Dialectical Behavioral Group Psychotherapy Compared to Supportive Individual Psychotherapy in Patients…
- Trial name
- DBT BPD (NCT07449104)
- Testing
- DBT group psychotherapy, Supportive Psychotherapy
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Natalia Dewi Wardani, MD
Borderline Personality Disorder
Screening of the Possible Risk Factors for Borderline Personality Disorders and Validation of Maclean Instrument
Borderline personality disorder is a mental illness that severely impacts a person's ability to regulate their emotions. This loss of emotional control can increase impulsivity, affect how a person feels about themselves, and…
- Trial name
- NCT05831852
- Testing
- no intervention
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Other Mental Conditions
Specialized Healthcare Service for BPD Patients: Athens Trial
A quasi-experimental pragmatic trial was developed to evaluate a specific health-care service for the treatment of biporal personality disorder (BPD) patients.The effectiveness and economic evaluation (cost-effectiveness and…
- Trial name
- BPDAS (NCT06392139)
- Testing
- Specific Therapy Program for Personality Disorders, Treatment As Usual (TAU) Group
- Where
- 3 sites in Greece
- Volunteers
- 156 people
- Sponsor
- Ioannis A. Malogiannis
Borderline Personality Disorder
Biomarkers of Change in BPD After Metacognitive Interpersonal Therapy-standard Approach
The present randomised clinical trial aims to assess the clinical and neurobiological changes following Metacognitive Interpersonal Therapy -standard approach (MIT-SA) compared with Clinical Structured Treatment (CST) derived…
- Trial name
- CLIMAMITHE (NCT02370316)
- Testing
- Metacognitive Interpersonal Therapy (MIT-SA), Clinical Structured Treatment
- Where
- Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Borderline Personality Disorder
A Double Blind Crossover Study on the Effect of MPH on Decision-making Ability of Adults With BPD Compared to Adults With ADHD and Healthy Adults
The study assesses the effect of Ritalin on working memory,attention,and decision-making measures in adults with BPD and compares it to its effect on healthy adults and adults with BPD (using data form study SHA 01-10), in a…
- Trial name
- NCT01426984
- Testing
- methylphenidate
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Shalvata Mental Health Center
Borderline Personality Disorder
Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder
Selegiline is superior to placebo in improving psychological and physical functioning in patients with Borderline Personality Disorder.
- Trial name
- NCT01912391
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mood and Anxiety Research, Inc
Mentalisation, Mentalization
Mentalization-Based Therpay With Older Adults
The investigators would like to find out if Mentalization-Based Therapy (MBT) is effective for people aged 60+ who struggle in relationships.
- Conditions
- Mentalisation, Mentalization, Later Life, Older Adults
- Trial name
- NCT07065071
- Testing
- Mentalization-Based Therapy
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- University of Nottingham
Posttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)
Extended Group Written Exposure Therapy for Comorbid PTSD and BPD (Traits)
The goal of this open label trial is to evaluate the effectiveness of virtual group extended Written Exposure Therapy (GE-WET) in reducing Post-Traumatic Stress Disorder (PTSD) symptoms in patients with comorbid PTSD and…
- Trial name
- NCT07576387
- Testing
- Group Written Exposure Therapy
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Borderline Personality Disorder
DBT in Borderline Personality Disorder
Subjects will receive a 6-month course of DBT, consisting of one 90-minute group and one 60-minute individual session per week as well as telephone availability of the individual therapist.
- Trial name
- NCT00252031
- Testing
- Dialectical Behavioral Therapy
- Where
- United States
- Sponsor
- Bronx VA Medical Center
Borderline Personality Disorder
Staff Nurse Perceptions of MBT Skills Training for Working With BPD in AMH
Despite expert opinion unconvinced of any value for hospitalization in caring for people with borderline personality disorder (BPD), this patient group still accounts for a significant proportion of adult acute mental health…
- Trial name
- NCT02239055
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen