Clinical trials: Borderline Personality Disorder
Borderline Personality Disorder, Mothers
Parenting Skills for Mothers With Borderline Personality Disorder (BPD)
The first disorder-specific parenting training program for mothers with Borderline Personality Disorder (M-BPD) is evaluated in a randomized controlled trial.
- Trial name
- ProChild (NCT04169048)
- Testing
- Group training for mothers with Borderline Personality Disorder
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
Self-Harm, Deliberate, Borderline Personality Disorder
Dialectical Behavior Therapy vs Enhanced Usual Care for Suicidal and Self-harming Adolescents. 10 Year Follow-up
The purpose of the study is to evaluate the long-term efficacy of dialectical behavior therapy (DBT) in treatment of adolescents with deliberate self harm compared to enhanced usual care (EUC).
- Trial name
- NCT04298190
- Testing
- Dialectical Behaviour Therapy for Adolescents (DBT-A), Enhanced usual care
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Oslo University Hospital
Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder
Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD
The purpose of this study is to investigate how emotional and non-emotional regulation processes differ in EIP patients (with different levels of ADHD symptoms/ADHD-comorbidity) compared to controls.
- Conditions
- Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder, Healthy Controls
- Trial name
- NCT02797873
- Testing
- fMRI - Stroop task, fMRI - MID task, Stop Signal Task
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Borderline Personality Disorder
Five Factor Model Treatment for Borderline Personality Disorder
The primary purpose of this study is to explore acceptability, feasibility, and preliminary efficacy of a novel cognitive-behavioral treatment for borderline personality disorder (BPD).
- Trial name
- NCT04587518
- Testing
- Personality-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Borderline Personality Disorder
Personality Change Study for Borderline Personality Disorder
Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment.
- Trial name
- NCT06005129
- Testing
- Personality-Based Therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Emotional Dysregulation
Patients Suffering From Emotional Dysregulation
Emotional dysregulation (ED) is a common syndrome in psychiatric disorders. It is characterized by intense emotions, easily triggered, and with significant psychological impact: explosions of anger, irritability, impulsivity…
- Trial name
- Dys-Emotion (NCT06616337)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Self Harm, Suicide, Attempted
DBT-SS for Cognitively Challenged Individuals With Deliberate Self-harm
The study evaluates the effect of Dialectic Behavior Therapy Skills System (DBT-SS) in individuals with Intelligence Quotient 65-85 and recurrent self-harm.
- Conditions
- Self Harm, Suicide, Attempted, Borderline Personality Disorder
- Trial name
- NCT03627663
- Testing
- Dialectic Behavior Therapy - Skills System
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Region Skane
Borderline Personality Disorder
MDMA in Borderline Personality Disorder
The purpose of this study is to test the effects of MDMA (3,4-methylenedioxymethamphetamine) on social cognition in adults with Borderline Personality Disorder.
- Trial name
- MDMA in BPD (NCT06683014)
- Testing
- MDMA
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Relatives
A Smartphone Application of "Family Connections" to Relatives of People With Borderline Personality Disorder.
The aims of our study are the following: (a) testing the effectiveness of a combined intervention: "Family Connections" program with a smartphone app versus the same intervention supported by a paper-based manual, (b) studying…
- Trial name
- NCT05215392
- Testing
- Family Connections program
- Where
- Spain
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Borderline Personality Disorder
MBT-early: a Single Case Experimental Design
Borderline personality disorder (BPD) is characterized by problems in emotion regulation, identity disturbances, and impaired interpersonal functioning.
- Trial name
- NCT06212024
- Testing
- Mentalization Based Treatment-early
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- De Viersprong
Borderline Personality Disorder
Effectiveness of a Short and Telematic Version of Cognitive-behavioral Treatment for Borderline Personality Disorder
Standard Dialectical Behavioral Therapy (DBT)is an effective treatment for Borderline Personality Disorder (BPD), particularly for patients with significant behavioral and affective dysregulation, including suicidality.
- Trial name
- NCT04829253
- Testing
- Dialectical Behavior Therapy -3-months, Dialectical Behavior Therapy -6-months
- Where
- Chile
- Volunteers
- 240 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Borderline Personality Disorder, Emotional Instability
Using Smartphones for Selfmonitoring of Skill-use i Dialectical Behavior Therapy
BACKGROUND: Borderline Personality Disorder (BPD) is a serious and debilitating mental disease characterized by difficulties with emotion regulation that leads to unstable and self- destructive behavior and relationships.
- Conditions
- Borderline Personality Disorder, Emotional Instability, Skill, Coping
- Trial name
- mDIARY (NCT03191565)
- Testing
- Paper diary sheet, Monsenso DBT-app and IT monitoring program
- Where
- 5 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Region of Southern Denmark
Borderline Personality Disorder (BPD)
Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder
We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.
- Trial name
- NCT07091409
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Borderlone Personality Disorder
Low-Dose Risperidone Treatment for Subjects Suffering From Borderline Personality Disorder
Personality disorders are life-long maladaptive behavioral patterns. Borderline personality disorder (BPD) is the leading personality disorder encountered in clinical settings, often associated with tremendous distress.
- Trial name
- NCT00633802
- Testing
- Risperidone
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Borderline Personality Disorder
A Study to Test Different Doses of BI 1358894 and Find Out Whether They Reduce Symptoms in People With Borderline Personality Disorder
This study is open to adults with borderline personality disorder. The purpose of this study is to find out whether a medicine called BI 1358894 helps to reduce symptoms in people with borderline personality disorder.
- Trial name
- NCT04566601
- Testing
- BI 1358894
- Where
- 67 sites in United States, Argentina and 13 more
- Volunteers
- 390 people
- Sponsor
- Boehringer Ingelheim
Posttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)
Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and BPD
The goal of PROSPER-B is to study effectiveness of EMDR compared to integrated DBT-EMDR in treatment-seeking, adult patients with comorbid PTSD and Borderline Personality Disorder (BPD).
- Trial name
- PROSPER-B (NCT03833453)
- Testing
- EMDR, DBT
- Where
- Netherlands
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Arkin
Borderline Personality Disorder
Quetiapine Treatment for Symptoms Associated With Borderline Personality Disorder
Objective: The objective of this study is to quantitatively examine the efficacy of Seroquel (active ingredient quetiapine fumarate) in subjects with Borderline Personality Disorder (BPD).
- Trial name
- NCT00122070
- Testing
- Quetiapine Fumarate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Dentistry of New Jersey
Borderline Personality Disorder
Ketamine in Borderline Personality Disorder
The purpose of this study is to test the potential of the rapid-acting anti-depressant ketamine to decrease suicidality in Borderline Personality Disorder (BPD).
- Trial name
- NCT03395314
- Testing
- Ketamine, Midazolam
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Yale University
Borderline Personality Disorder
The Influence of Treatment Format on Schema Therapy for Borderline Personality Disorder
The goal of this clinical trial is to compare etc. in patients with borderline personality disorder pure individual schema therapy to combined individual-group schema therapy.
- Trial name
- IST-IGST (NCT05986552)
- Testing
- Individual Schema Therapy (IST), Individual-Group Schema Therapy (IGST)
- Where
- 3 sites in Netherlands
- Volunteers
- 132 people
- Sponsor
- University of Amsterdam
Posttraumatic Stress Disorder, Borderline Personality Disorder
STAIR for Trauma and Emotion Dysregulation
This study will examine the impact of Skills Training in Affective and Interpersonal Regulation (STAIR) group, using self-report measures, on Posttraumatic Stress Disorder (PTSD), emotional dysregulation, borderline personality…
- Conditions
- Posttraumatic Stress Disorder, Borderline Personality Disorder, Emotion Regulation
- Trial name
- NCT05397613
- Testing
- STAIR
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University