Clinical trials: Bone Strength
Bone Loss, Bone Loss, Age-related
Strength Training for Osteoporosis Prevention During Early Menopause
The goal of this clinical pilot trial is to learn about the feasibility of a high-intensity resistance training intervention in peri- and early menopausal females.
- Conditions
- Bone Loss, Bone Loss, Age-related, Osteoporosis, Musculoskeletal Diseases
- Trial name
- STOP-EM (NCT05961371)
- Testing
- Resistance Training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Vitamin D Insufficiency
25(OH)-Vitamin D and Its Association With Structural and Functional Parameters in Hospitalized Patients With Neurological Diseases
The NeuroVitD study aims to assess vitamin D levels in hospitalized cohorts with neurological disorders resulting in motor disabilities, providing epidemiological data necessary for guidelines.
- Trial name
- NeuroVitD (NCT06791044)
- Testing
- DELTIUS
- Where
- 2 sites in Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dionyssiotis, Yannis, M.D.
Vitamin D Deficiency
Effects of Vitamin D Supplementation on Strength, Bone Density, and Injury Risk in Collegiate Athletes
The goal of this study is to determine whether Vitamin D supplementation improves strength and bone density, and reduces the risk of injury in collegiate athletes.
- Trial name
- NCT03151174
- Testing
- Vitamin D 10000 UNT, Vitamin D 5000 UNT
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Bone Strength, Neuromuscular Function
The Influence of High Impact Exercise on Musculoskeletal Health in Older Men
Osteoporotic fractures are an extremely common and serious public health issue which contribute substantially to pain, impaired mobility and morbidity in the elderly.
- Trial name
- Hiphop (NCT02007460)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Osteoporosis, Breast Cancer
Effects of Exemestane on Bone Strength
The NCIC CTG was conducting an international breast cancer prevention trial (MAP.3) examining the effects of a new therapy (exemestane) for breast cancer prevention in postmenopausal women at increased risk of developing this…
- Trial name
- MAP3BSS (NCT01144468)
- Where
- 4 sites in United States, Canada
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Maintaining Bone Strength in Men With Prostate Cancer
The purpose of this study is to see if giving zoledronic acid three times a year is as effective as five times a year, in increasing bone strength in men with prostate cancer.
- Trial name
- NCT00391950
- Testing
- Zoledronic acid
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Novartis
Weight Loss, Bone Health
Incorporating Nutrition, Vests, Education, and Strength Training in Bone Health (INVEST in Bone Health)
The main goal of the proposed study is to compare the effects of weight loss (WL) alone with WL plus weighted vest use or WL plus resistance exercise training (RT) on indicators of bone health and subsequent fracture risk.
- Trial name
- INVEST (NCT04076618)
- Testing
- Vest, Resistance Exercise Training, weight loss program
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Wake Forest University Health Sciences
Osteoporosis
Effects of Clinical Pilates and Whole Body Vibration Exercises in Postmenopausal Osteoporotic Women
The aim is to compare the effects of clinical pilates and whole body vibration exercises in postmenopausal osteoporotic women on strength, flexibility, balance, bone turnover markers and quality of life.
- Trial name
- NCT04259697
- Testing
- Clinical pilates, Whole body vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Dokuz Eylul University
Hip Fracture
Training of Patients With Hip Fracture
The primary purpose of this study is to illustrate whether there is a difference in the 6 minutes walking test in patients with hip fractures who have received 6 vs. 12 weeks of physical training after discharge from hospital.
- Trial name
- NCT01174589
- Testing
- Strength training
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Lolland Community, Denmark
Osteoporosis, Sarcopenia
Effectiveness of Creatine Supplementation and Exercise on Muscle and Bone
As we age, we experience a reduction in muscle and bone which inevitably decreases strength and the ability to perform tasks of daily living such as gardening, carrying groceries, and climbing stairs.
- Trial name
- NCT01057680
- Testing
- creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Postmenopausal Women
Pilates Plus Whole-Body Vibration in Postmenopausal Women
This controlled, quasi-experimental clinical trial investigated the effects of a combined Pilates and whole-body vibration (WBV) intervention on bone mineral density (BMD), muscle strength, postural balance, and quality of life…
- Trial name
- Pilates_WBV (NCT07460388)
- Testing
- Pilates plus whole-body vibration
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana
Hip Fractures (ICD-10 72.01-72.2), Frailty at Older Adults
Frailty Intervention in Postoperative Hip Fracture Inpatients
Hip fracture is a big health concern in older adults, and can lead to increased risk of death, reduced level of independence \& mobility, reduced quality of life, and higher likelihood of admission to nursing homes.
- Conditions
- Hip Fractures (ICD-10 72.01-72.2), Frailty at Older Adults, Strength Training, Resistance Training
- Trial name
- NCT07027241
- Testing
- Exercise Intervention, Usual Care, Nutritional Intervention
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- Royal College of Surgeons, Ireland
Anterior Cruciate Ligament Injury
BPTB Versus Hamstring Autografts in ACL Reconstruction Among Professional Athletes
This prospective randomized controlled study compares outcomes of ACL reconstruction using bone-patellar tendon-bone (BPTB) versus hamstring tendon (HT) autografts in professional athletes.
- Trial name
- BPTB-HT ACL (NCT07573293)
- Testing
- BPTB ACL Reconstruction, Hamstring ACL Reconstruction
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Cairo University
Coxarthrosis, Fracture of Femoral Neck
Zink and Bone Strength
Zink and bone strength
- Trial name
- NCT00317863
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoporosis
Treatment of Osteopenia With Melatonin
The aim of the study is to assess the effect of melatonin treatment in patients with osteopenia on BMD, muscle function, quality of life and calcium homeostasis.
- Trial name
- MelaOst (NCT01690000)
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Chronic Disease, Frail
Functional Exercise and Nutrition Education Program for Older Adults
There is strong evidence that specific types of exercise can improve health and physical function in older adults. While community exercise classes exist, many older adults with chronic conditions may need guidance from…
- Conditions
- Chronic Disease, Frail, Diabetes Mellitus, Cancer
- Trial name
- MoveStrong (NCT04037436)
- Testing
- Strength and Balance Training & Nutrition Education, Usual Care
- Where
- 5 sites in Canada
- Volunteers
- 44 people
- Sponsor
- University of Waterloo
Diabetes Mellitus, Type 2
Advanced Glycation Endproducts and Bone Material Strength in T2D Treated With Pyridoxamine
The purpose of this study is to determine if a specific form of Vitamin B known as Pyridoxamine helps improve bone strength over one year in women (>65 yrs old) with Type 2 Diabetes.
- Trial name
- NCT03778580
- Testing
- Pyridoxamine Dihydrochloride
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Columbia University
Type1diabetes
Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength
The purpose of this research study is to find out how bones are affected in children and adolescents with type 1 diabetes (T1D) as compared to children and adolescents without type 1 diabetes.
- Trial name
- NCT04289727
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Columbia University
Maternal Vitamin D Status, Neonatal Bone Quantitative Ultrasound Measurements
Maternal Vitamin D Status and Neonatal Bone Strength
Objectives: 1. To determine the incidence of vitamin D deficiency among Israeli pregnant women 2. To access whether maternal vitamin D status affects infant bone strength. Methods: 1.
- Trial name
- Vitamin D (NCT01630603)
- Where
- 3 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Bone Density, Muscle Weakness
Whole Body Vibration in Middle Aged Men
This study aims of this clinical trial is to evaluate the effect of an 8-week Whole Body Vibration (WBV) intervention on Bone Mineral Density (BMD), hand grip strength, and vitamin D levels in middle-aged men.
- Trial name
- NCT06644469
- Testing
- Dynatronics VF5 Model vibration platform
- Where
- Saudi Arabia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Jouf University