Clinical trials: Bone Health
Lactation Bone Loss, Infant Bone Growth
Effect of Calcium Plus Vitamin D Supplementation on Adolescent Mother and Infant Bone Health
Pregnancy and lactation are periods of high calcium requirement. Inadequate maternal calcium intake and vitamin D insufficiency may adversely affect fetal and neonatal growth and maternal bone mass particularly in adolescent…
- Trial name
- NCT01732328
- Testing
- Calcium plus vitamin D
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Bone Augmentation, Alveolar Ridge Augmentation
Alveolar Ridge Reconstruction in Post-extraction Sites Using a Magnesium Resorbable Membrane. An Explorative Study
When a tooth is removed, the surrounding bone and gum tissue naturally shrink over time. This shrinkage can make it harder to place a dental implant later and may affect the appearance of the smile.
- Trial name
- NOVAMAG-2024 (NCT07646795)
- Testing
- NOVAMag®
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Martina Stefanini
Herniated Intervertebral Disc
Artificial Intelligence Assisted Spine Rehabilitation in Cervical Disc Herniation
The aim of this study is to investigate the effect of artificial intelligence-assisted spinal rehabilitation in neck hernia compared to traditional methods.
- Trial name
- NCT06632028
- Testing
- artificial intelligence assisted spinal rehabilitation, conventional therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Okan University
Lumbar Disc Herniation
Effect of Feedback Health Education on Postoperative Rehabilitation of Patients With Lumbar Disc Herniation
Aims and Objective: A theoretical model based on guided postoperative rehabilitation with feedback was developed for patients with lumbar intervertebral disc protrusion to explore the effects of feedback-based health education.
- Trial name
- NCT04885140
- Testing
- Feedback-based health education, Routine health education
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tianjin Hospital
Osteoporosis
Green Tea and Tai Chi for Bone Health
Osteoporosis is a major health problem in postmenopausal women. Our long-term goal is to develop a new alternative treatment that include a dietary supplement (green tea extract) and a mind-body exercise (Tai Chi) for lessening…
- Trial name
- GTP-TC-Bone (NCT00625391)
- Testing
- Green Tea Polyphenols (GTP), GTP+TC
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Osteoporosis Risk
Education Program on Increasing Osteoporosis Awareness Given to Women Aged 18-49
Summary Purpose: To examine the effect of the education program to increase osteoporosis awareness given to women aged 18-49. The research is carry out as a randomized controlled experimental in a pretest-posttest design.
- Trial name
- NCT05881850
- Testing
- Education Program on Increasing Osteoporosis Awareness Given to Women Aged 18-49. The research is carry out as a randomized controlled experimental in a pretest-posttest design.
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ankara University
Cognitive Performance, Age-Related Macular Degeneration
Lutein, Zeaxathin, and Fish Oil Supplementation
The goal of this clinical trial is to learn the impact of lutein, zeaxanthin, and fish oil (LZF) supplementation in healthy adults.
- Conditions
- Cognitive Performance, Age-Related Macular Degeneration, Bone Loss
- Trial name
- NCT06489873
- Testing
- Active Comparator (Lutein, zeaxanthin, and fish oil supplement (LZF)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Osteoporosis, Postmenopausal, Osteopenia
High-Intensity Laser Therapy and Physiotherapy for Bone Health in Postmenopausal Women: A Randomized Trial
The goal of this clinical trial is to learn if adding high-intensity laser therapy (HILT) to a physiotherapy programme helps bone health in women after menopause who have low bone density (osteopenia or osteoporosis).
- Trial name
- NCT07734922
- Testing
- High-Intensity Laser Therapy, Standardised Physiotherapy Programme
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Chronic Myelogenous Leukemia (CML)
Compliance: Role Emerges for Success in Chronic Myelogenous Leukaemia (CML): Evaluation aND Optimisation
This study on patient's compliance in clinical workaday life aims to assess and to improve CML treatment in Germany by means of adherence supporting measures and to increase adherence awareness by physicians and patients.
- Trial name
- Crescendo (NCT01243489)
- Testing
- compliance supporting measures
- Where
- 23 sites in Germany
- Volunteers
- 104 people
- Sponsor
- Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH
Osteoporosis, Osteopenia
Effects of Jumping on Bone Health in Young Women
This study evaluates the longitudinal, dose-dependent effects of jumping on bone health in young women. The women will be divided into 9 groups of varying jump height and repetitions, with a tenth group serving as control.
- Trial name
- NCT03413540
- Testing
- Jump
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- California State University, San Marcos
Autism Spectrum Disorder, Bone Health
Oxytocin Effects on Bone in Children With Autism Spectrum Disorder
This is a randomized, double blind, placebo-controlled study of the effects of intranasal oxytocin on bone health in children with autism spectrum disorder, ages 6-18 years old.
- Trial name
- BOX (NCT05754073)
- Testing
- 1. Intranasal oxytocin spray, 3. Intranasal Oxytocin spray
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Elizabeth Austen Lawson
Geriatric Hip Fracture
A Comparative Evaluation of Nottingham Hip Fracture Score (NHFS) and Acute Physiology and Chronic Health Evaluation (APACHE) II Score to Predict 30-day Mortality in Geriatric Patients Above 60 Years Undergoing Hip Fracture Surgery.
This study aims to compare the Nottingham Hip Fracture Score (NHFS) and the Acute Physiology and Chronic Health Evaluation II (APACHE II) score in predicting 30-day mortality in geriatric patients over 60 years old undergoing hip…
- Trial name
- NCT06598566
- Testing
- Nottingham Hip Fracture Score (NHFS) score, Acute Physiology and Chronic Health Evaluation (APACHE)-II score
- Where
- India
- Volunteers
- 182 people
- Sponsor
- Tata Main Hospital
Spinal Stenosis, Spondylolisthesis
Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures
The purpose of this retrospective data review is to evaluate the health economic drivers and complications of two surgical procedures: transsacral lumbar interbody fusion and transforaminal lumbar interbody fusion when used in…
- Conditions
- Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
- Trial name
- NCT02171169
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Baxano Surgical, Inc.
Stress Reaction
Validity for Stress Reduction of Virtual Reality Intervention
The purpose of this study is to verify the effect of virtual reality (VR) intervention on stress reduction for workers. After inducing stress by the Socially Evaluated Cold Pressure Test (SECPT), Investigators should explore…
- Trial name
- NCT07415239
- Testing
- virtual reality intervention, control intervention
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Soft Tissue Sarcoma, Bone Sarcoma
Assessment of the Functional Outcome and Quality of Life in Sarcoma Patients
Primary bone and soft tissue sarcomas are an exceptionally rare form of cancer, collectively accounting for only 1% of all malignancies diagnosed.
- Trial name
- QOLSarcoma (NCT05051059)
- Testing
- Functional outcome, Health related quality of life (HRQoL) assessment
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Multiple Osteochondroma, Ollier Disease
Ready to Sail: Evaluating Sailing's Feasibility as Ergotherapy
Background Individuals with rare skeletal disorders frequently experience psychological distress, social isolation, unmet needs, and significant challenges due to limited treatment options.
- Conditions
- Multiple Osteochondroma, Ollier Disease, Osteogenesis Imperfecta
- Trial name
- PaS (NCT06397443)
- Testing
- 5-day sailing activity
- Where
- Italy
- Volunteers
- 8 people
- Sponsor
- Istituto Ortopedico Rizzoli
Healthy, Bone
Bone and Inflammatory Outcomes - Nutrition and Exercise Trials
This study investigates whether dairy products will positively impact loading exercise-induced bone turnover and bone cell activity and/or the post-exercise inflammatory response in healthy young adults compared to a carbohydrate…
- Conditions
- Healthy, Bone, Inflammation
- Trial name
- BIONEX (NCT06041087)
- Testing
- High-Intensity Exercise, Carbohydrate (Maltodextrin powder mixed with water), Skim Milk
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- York University
Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL
Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors
This project will examine habitual physical activity, bone health, and insulin resistance in pediatric acute lymphocytic leukemia (ALL) and lymphoma cancer survivors at two time points: baseline and 6 months.
- Conditions
- Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL, Pediatric Lymphoma, Bone Loss
- Trial name
- HBHL (NCT04472286)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Hip Fractures, Covid19
COVID-19 Pandemic on Health Care and Rehabilitation Outcomes
Fragility fracture is easily associated with a clinical worsening of patients in terms of quality of life and disability in the medium and long term.
- Trial name
- HIP COVID (NCT04882670)
- Where
- Italy
- Volunteers
- 360 people
- Sponsor
- Istituto Ortopedico Rizzoli