Clinical trials: Bone Fractures
Femur Fracture, Femur Fracture Intertrochanteric
THP Hip Fracture Plating System Study
The objective of this study is to systematically document the clinical outcomes of THP Hip Fracture Plating System when used to treat intracapsular and intertrochanteric fractures.
- Conditions
- Femur Fracture, Femur Fracture Intertrochanteric, Garden Grade I Subcapital Fracture of Femoral Neck, Garden Grade II Subcapital Fracture of Femoral Neck
- Trial name
- THP (NCT03870477)
- Testing
- THP Hip Fracture Plating System with telescoping lag screws
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- Zimmer Biomet
Femur Fracture
Intramedullary Nailing of the Femur:Trochanteric vs Piriformis Starting Portals
This project is designed to determine whether or not the trochanteric insertion portal will show any difference when compared with the piriformis fossa portal in terms of pain and strength of the hip abductor muscles, while…
- Trial name
- TROCHNAIL (NCT00593333)
- Testing
- Antegrade Intramedullary Nail, Trigen Trochanteric Femoral Nail
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Alabama at Birmingham
Arthralgia, Trouble Balancing
Even-Up to Minimize Secondary Site Pain For Ankle Fracture
Evaluating impact of use of Even-Up shoe wear device for patients treated in CAM boot walker for an ankle fracture. Randomized controlled trial, randomizing patients into control group with boot treatment only versus boot…
- Trial name
- NCT04164563
- Testing
- Even-Up
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Tibial Delayed Healing
Tibial Delayed Healing Pivotal Clinical Trial
Evaluate the INFUSE/MASTERGRAFT™ Delayed Healing Device as an alternative/replacement to autograft in the treatment of tibial delayed healing.
- Trial name
- NCT01016067
- Testing
- INFUSE/MASTERGRAFT, Autograft bone
- Where
- 16 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Medtronic Spinal and Biologics
Elbow Fracture
The Post-Operative Pain Management of Pediatric Supracondylar Elbow Fractures
The goal of this study is to compare different ways of treating pain after surgery. This research study involves subjects who have a supracondylar elbow fracture and need surgery.
- Trial name
- NCT01328782
- Testing
- Oxycodone with Acetaminophen, Bupivacaine 0.25%, Ropivacaine 0.20%
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Colorado, Denver
Rib Fractures, Trauma
Continuous Erector Spinae Plane Blocks for Rib Fractures
Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to…
- Conditions
- Rib Fractures, Trauma, Anesthesia, Anesthesia, Local
- Trial name
- NCT04558281
- Testing
- Active ropivacaine 0.3% erector spinae plane perineural administration
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
Osteoarthritis Shoulder, Fracture
Multi Centre Study on TESS V2 Shoulder System
This study is a Post Market Clinical Follow-up study to fulfill the post market surveillance requirements. The data collected from this study will serve the purpose of confirming safety and performance of the TESS Shoulder System.
- Conditions
- Osteoarthritis Shoulder, Fracture, Rheumatoid Arthritis, Avascular Necrosis
- Trial name
- NCT03431857
- Testing
- TESS V2
- Where
- 2 sites in Belgium, France
- Volunteers
- 106 people
- Sponsor
- Zimmer Biomet
Humerus Fracture Metastatic Bone Disease
Safety and Efficacy Study of Treatment of Pathological Fractures in Humerus
This study will collect safety and performance data of the Photodynamic Bone Stabilization System (PBSS) when used for the treatment of fractures of the humerus secondary to metastatic cancer.
- Trial name
- NCT02338492
- Testing
- Photodynamic Bone Stabilization System
- Where
- 13 sites in United States
- Volunteers
- 81 people
- Sponsor
- IlluminOss Medical, Inc.
Tibial Fractures, Leg Injuries
Light Therapy in the Treatment of Leg Pain
The purpose of this study is to apply Anodyne therapy to active duty soldiers, who have shin splints, to evaluate healing time and effectiveness.
- Trial name
- MilCAM (NCT00253981)
- Testing
- Monochromatic Near-Infrared Light Energy (MIRE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Samueli Institute for Information Biology
Knee Injuries
Trial Comparing BST-CarGel and Microfracture in Repair of Articular Cartilage Lesions in the Knee
This study will investigate whether the treatment of damaged cartilage in the knee with BST-CarGel will increase the amount and quality of cartilage repair tissue when compared with microfracture alone.
- Trial name
- NCT00314236
- Testing
- BST-CarGel with Microfracture, Microfracture without BST-CarGel
- Where
- 18 sites in Canada, South Korea and 1 more
- Volunteers
- 80 people
- Sponsor
- Piramal Healthcare Canada Ltd
Intra-Articular Fractures
Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures
The purpose of this study is to examine the effect of early, percutaneous, intra-articular saline lavage on the undiluted synovial fluid microenvironment during the acute phase following intra-articular fracture of the human…
- Trial name
- NCT05465382
- Testing
- Saline Lavage, No intra-articular saline lavage, Lidocaine - intra-articular injection
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Duke University
Osteoporotic Fractures, Spinal Fractures
Build Better Bones With Exercise
The long-term goal of our research team is to conduct a large multicentre study to evaluate whether tailored home exercise can prevent fractures in high-risk individuals.
- Trial name
- B3E (NCT01761084)
- Testing
- Exercise and behaviour change strategies
- Where
- Canada
- Volunteers
- 141 people
- Sponsor
- University of Waterloo
Fusion of Spine (Disease), Fractures, Ununited
A Clinical Registry to Collect Patient Outcome Date for the BIOMET® Stimulator Systems
The purpose of this clinical registry is to capture data on an ongoing basis from a population of patients who will use Biomet's BHS, OrthoPak and SpinalPak devices.
- Trial name
- NCT01750840
- Testing
- Biomet® EBI Bone Healing System, Biomet Orthopak® Non-Invasive Bone Growth Stimulator System, Biomet SpinalPak® Non-Invasive Spine Fusion Stimulator
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Zimmer Biomet
Fracture
Platelet Rich Plasma Injection in Pilon Fractures
Patients who sustain broken ankles have a very high risk of developing arthritis soon after injury (within 2 years). This arthritis can cause increased pain and a decrease level of function, especially if the injury occurs at an…
- Trial name
- NCT02481869
- Testing
- Arthrocentesis/PRP, Arthrocentesis/Saline
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Missouri-Columbia
Fracture Fixation, Intra-Articular Fractures
Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat (Vitagel)
The purpose of the study is to determine whether surgical hemostats can minimize blood loss, need for allogeneic blood transfusions and their associated risks, and costs in patients with certain acetabular fractures requiring…
- Conditions
- Fracture Fixation, Intra-Articular Fractures, Acetabulum
- Trial name
- NCT01230931
- Testing
- Vitagel, Standard of care
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- The University of Texas Health Science Center, Houston
Rib Fractures
Intercostal Cryoneurolysis Following Traumatic Rib Fractures
Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to…
- Trial name
- NCT03917823
- Testing
- Cryoneurolysis
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
Osteoporosis
Comparison of the Effect of an Ongoing Treatment With Alendronate or a Drug Holiday on the Fracture Risk in Osteoporotic Patients With Bisphosphonate Long Term Therapy
The purpose of this study is to evaluate the efficacy and safety of bisphosphonates in long term treatment of osteoporosis.
- Trial name
- BILANZ (NCT01512446)
- Testing
- Alendronate
- Where
- Germany
- Volunteers
- 436 people
- Sponsor
- Evangelisches Krankenhaus Lutherhaus gGmbH
Postmenopausal Osteoporosis
A Study of Romosozumab (EVENITY®) in Postmenopausal Women in India With Osteoporosis at a High Risk of Fracture.
The primary objective of this study is to characterize safety and tolerability of romosozumab in postmenopausal women with osteoporosis and a high risk of fracture in India.
- Trial name
- NCT06079476
- Testing
- Romosozumab
- Where
- 10 sites in India
- Volunteers
- 100 people
- Sponsor
- Amgen
Femoral Neck Fractures
Safety Study of Femoral Neck Fracture System
The purpose of this study is to assess the reoperation rate of fractures that have occurred at the neck of the femur that are treated with the CONQUEST FN Femoral Neck Fracture System.
- Trial name
- CONQUEST FN (NCT03721835)
- Testing
- CONQUEST FN Femoral Neck Fracture System
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- Smith & Nephew, Inc.
Fracture of Shaft of Radius and/or Ulna, Metaphyseal Fracture of Bone of Upper Limb
Is Univalving or Bivalving of Long Arm Casts for Forearm Fractures Necessary?
This study aims to examine the need for univalve or bivalve splitting of casts in pediatric patients with forearm fractures following closed reduction and cast application in a randomized, prospective fashion.
- Conditions
- Fracture of Shaft of Radius and/or Ulna, Metaphyseal Fracture of Bone of Upper Limb, Fracture of Upper Limb, Level Unspecified
- Trial name
- NCT02614690
- Testing
- No Split Cast of forearm fractures, Univalve Split Cast of forearm fractures, Bivalve Split Cast of forearm fractures
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Connecticut Children's Medical Center