Clinical trials: Bone Fractures
Fractures, Bone, CKD Stage 4
The Effect of Prophylactic Anticoagulation on Major Bleeding Events in Hospitalized Chronic Kidney Disease and Lower Limb Fracture Patients.
the risk of bleeding may be greater than the benefit of antithrombotic protection when prophylactically anticoagulating a patient with a lower limb fracture and advanced CKD.
- Conditions
- Fractures, Bone, CKD Stage 4, CKD Stage 3, CKD Stage 5
- Trial name
- FAA (NCT06795698)
- Testing
- Enoxaparin
- Where
- Mexico
- Volunteers
- 61 people
- Sponsor
- Hospital Civil de Guadalajara
Thromboembolism
Observational Study of Thrombogenic Properties in 220 Patients With Proximal Femur Fracture
Measurement of thrombogenic properties by TEG and MEA and observation of thrombotic events over 2 years in 220 patients with hip fracture.
- Trial name
- thro-fract15 (NCT02475187)
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- Vestre Viken Hospital Trust
Humerus Pathological Fracture
A Safety and Efficacy Study of the Treatment of Impending and Actual Pathological Fractures in the Humerus From Metastatic Bone Disease
The purpose of this study is to collect safety and performance data of the Photodynamic Bone Stabilization System (PBSS) when used for the treatment of painful impending and actual fractures of the humerus secondary to metastatic…
- Trial name
- NCT02373904
- Testing
- Photodynamic Bone Stabilization System
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 14 people
- Sponsor
- IlluminOss Medical, Inc.
Hip Fractures
Blind Fascia Iliaca Compartment Block Compared to Ultrasound-guided Femoral Nerve Block in Patients With Hip Fractures
The goal of this study is to compare the analgesic effect of a blind fascia iliaca compartment block to an ultrasound-guided femoral nerve block in patients that present to the emergency department with hip fractures.
- Trial name
- NCT05365555
- Testing
- Fascia Iliaca Compartment Block, Femoral Nerve Block, Ropivacaine
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- University Hospital, Linkoeping
Femur Fracture
Pediatric Femur Research Project
Current treatment protocol for pediatric femoral shaft fractures is immediate spica casting for patients 6 years and younger and for patients over 6 years and older is percutaneous or open placement of titanium elastic…
- Trial name
- NCT00943332
- Testing
- femur fracture repair
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Ankle Malleolus Fracture Bimalleolar, Fracture of Medial Malleolus
Non--operative Treatment of the Medial Malleolus in bi- and Trimalleolar Ankle Fractures
The purpose of this study was to determine if internal fixation of the medial malleolus is necessary following open reduction and internal fixation of the lateral and, if required, the posterior malleolus treating displaced bi-or…
- Conditions
- Ankle Malleolus Fracture Bimalleolar, Fracture of Medial Malleolus, Fracture of Ankle
- Trial name
- NCT01441817
- Testing
- Internal fixation
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Hip Fractures, Abdominal Surgery
Validation of Two Acitivity Monitors in Three Inpatient Populations.
The aim of this study is to investigate the validity of Sens Motion and ActivPAL acitivity monitors. Thirthy-six patients from three different patient populations will be included: 12 acute high-risk abdominal surgery patients…
- Conditions
- Hip Fractures, Abdominal Surgery, Medical Patients
- Trial name
- NCT04120740
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Mette Merete Pedersen
Fracture, Scoliosis Idiopathic Adolescent
Opioid Analgesia Impacts on Neurological Development
Background: Pain in childhood - whether from injuries like fractures or long-term conditions like scoliosis - is often treated with opioid medicines. These drugs are effective for pain relief.
- Conditions
- Fracture, Scoliosis Idiopathic Adolescent, Traumatic Injury, Adolescent
- Trial name
- OPAL (NCT07855952)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Postoperative Pain, Fracture Femur
Preoperative and Postoperative Comparison of Two Nerve Blocks in Intertrochanteric Fracture Surgery
Patients with intertrochanteric femur fractures experience significant perioperative and postoperative pain. Perioperative pain can complicate and prolong the anesthesia process for patients undergoing spinal anesthesia, leading…
- Trial name
- NCT07075432
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Erzincan University
Distal Femoral Fractures, Extra-articular Distal Radius Malunions
Retrograde Nail vs Double Plating for Distal Femoral Extra and Simple Articular Fractures With Metaphyseal Comminution
The objective of this study is to compare the short term functional clinical and radiological outcomes of retrograde nail versus double plating for distal femoral extra-articular and simple articular fractures with metaphyseal…
- Conditions
- Distal Femoral Fractures, Extra-articular Distal Radius Malunions, Intramedullary
- Trial name
- NCT07542249
- Testing
- Retrograde nail, Double plating
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Hip Fractures, Tibial Fractures
Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
Prospective data will be collected in approximately 3500 patients (700 per 5 injury groups). Patients will be followed up according to the standard (routine) for up to 1 year after the treatment.
- Conditions
- Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal
- Trial name
- NCT04113044
- Testing
- All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 1,500 people
- Sponsor
- AO Innovation Translation Center
Thoracolumbar Spine Fracture, Facet Joint Degeneration
Degenerative Changes After Treatment of Thoracolumbar Junction Fractures
This observational study will evaluate how degenerative changes in the facet joints and intervertebral discs develop over time after treatment of AOSpine type A2, A3, and A4 fractures of the thoracolumbar junction.
- Conditions
- Thoracolumbar Spine Fracture, Facet Joint Degeneration, Intervertebral Disc Degeneration
- Trial name
- NCT07672184
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sklifosovsky Institute of Emergency Care
Post-Menopausal Osteoporosis
Intra-venous Zoledronic Acid Once Yearly
The study will assess the real life effectiveness of zoledronic acid in the management of patients with osteoporosis over 4 years of treatment.
- Trial name
- IVORY (NCT00984893)
- Testing
- zoledronic acid, Any oral bisphosphonates marketed in Canada
- Where
- 3 sites in Canada
- Volunteers
- 1,551 people
- Sponsor
- Novartis Pharmaceuticals
Bone Fractures
Ultrasound Assessment of Pediatric Fracture Healing With the PLUS Score
This observational study investigates whether ultrasound can safely and accurately monitor the healing of bone fractures in children, comparing it to standard X-rays.
- Trial name
- USG-FRACTHEAL (NCT07755787)
- Testing
- Point-of-care ultrasound
- Where
- Czechia
- Volunteers
- 1,200 people
- Sponsor
- University Hospital Hradec Kralove
Distal Radius Fracture
BFR Therapy Following DRF
This study's goal is to evaluate whether blood flow restriction supplemented therapy is a superior therapy compared to traditional standard of care while recovering from a surgery that repairs distal radius fractures.
- Trial name
- NCT05396521
- Testing
- Blood Flow Restriction, Standard of Care Physical Therapy
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Osteoporosis, Fractures
Strategies Targeting Osteoporosis to Prevent Recurrent Fractures
An evidence-based quality improvement intervention will overcome multiple barriers to best practice and improve rates of diagnosis and effective treatment for osteoporosis in high-risk patients.
- Trial name
- NCT00152321
- Testing
- Patients (education, counseling) and Physicians (reminders,1-page guidelines)., Multifaceted intervention, Usual Care
- Where
- Canada
- Volunteers
- 242 people
- Sponsor
- University of Alberta
Non-inflammatory Degenerative Joint Disease, Rhematoid Arthritis
Tornier Perform™ Reversed Monopost Study
This study is a Multi-center, Prospective Follow-up, Non-significant risk, Post-Market Clinical Follow-Up (PMCF) study to Evaluate the Safety and Effectiveness of the Tornier Perform™ Reversed MonoPost System.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Rhematoid Arthritis, Correction of Functional Deformity, Fracture of the Humeral Head
- Trial name
- Monarch (NCT07764614)
- Testing
- Tornier Perform™ Reversed MonoPost
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Stryker Trauma and Extremities
Clavicle Fracture
Intramedullary Screw Versus Plate in Displaced Midshaft Clavicle Fractures
This study compares two operative managements of midshaft clavicle fractures: intramedullary screw and plate fixation. In the past ten years, many studies have compared non operative management versus operative fixation and in…
- Trial name
- PlaClaVis (NCT05262998)
- Testing
- Plate fixation, Intramedullary Screw
- Volunteers
- 60 people
- Sponsor
- Bichat Hospital
Humeral Fracture, Proximal, Revision of a Shoulder Prosthesis
Retro-Prospective Postmarket Clinical Study For FX Shoulder Solutions Long Cemented HUMELOCK II®
This study takes place in the framework of the PostMarket Clinical Follow-up plan of the HUMELOCK II(r) long cemented humeral stem (shoulder prosthesis) commercialized by FX SHOULDER SOLUTIONS.
- Trial name
- NCT07663552
- Testing
- Shoulder arthroplasty
- Where
- 4 sites in France
- Volunteers
- 40 people
- Sponsor
- FX Solutions
Femur Fracture, Hip Surgery
Pericapsular Nerve Group (PENG) Block on Pain During Participant Positioning for Spinal Anesthesia in Hip Fracture Surgery
Hip fracture surgery is a common orthopedic procedure, especially in elderly patients. These fractures are quite common in adults over the age of 65, and the one-year mortality rate ranges from 12% to 37%.
- Trial name
- NCT06813755
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Marmara University