Clinical trials: Bone Fractures
Traumatic Arthropathy of Shoulder, Fracture Humerus
Perform® Humeral System - Fracture Study (PFX)
This study is an international, single arm, multicenter, prospective follow-up, non-significant risk, Post-Market Clinical Follow-up (PMCF), which is designed to collect safety and performance data on commercially available…
- Conditions
- Traumatic Arthropathy of Shoulder, Fracture Humerus, Traumatic Arthritis, Revision of Other Devices if Sufficient Bone Stock Remains
- Trial name
- PFX (NCT05773352)
- Testing
- Tornier Perform® Humeral System - Fracture
- Where
- 9 sites in United States
- Volunteers
- 118 people
- Sponsor
- Stryker Trauma and Extremities
Zygomaticomaxillary Complex (ZMC) Fractures
Evaluation of Custom-Made Plates in the Treatment of Zygomaticomaxillary Complex (ZMC) Fractures.
This prospective, single-arm clinical trial evaluated the clinical and radiographic outcomes of custom-made, 3D-printed titanium plates in the surgical treatment of unilateral zygomaticomaxillary complex (ZMC) fractures.
- Trial name
- NCT07788885
- Testing
- Custom-made 3D-printed titanium plate
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Al-Azhar University
Distal Tibial Fracture, Tibial Fracture
Elastic Nailing With Kirschner Wires Versus Plate Fixation for Distal Tibial Fractures in Adolescents
This prospective randomized controlled trial will compare two surgical methods for treating distal tibial metaphyseal-diaphyseal junction fractures in adolescents aged 10 to 16 years.
- Conditions
- Distal Tibial Fracture, Tibial Fracture, Fracture Fixation, Intramedullary, Fracture Fixation, Internal
- Trial name
- NCT07783529
- Testing
- Elastic Stable Intramedullary Nailing Supplemented by Kirschner Wires, Plate fixation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Scaphoid Fracture, Scafoïd; Fracture
Diagnostics of Scaphoid Fractures With HRpQCT
The scaphoid bone is the most common fractured carpal bone. Scaphoid fractures represent 2-6% of all fractures and occur mainly in young, active patients aged 15 to 40.
- Trial name
- NCT03899025
- Testing
- CT
- Where
- Netherlands
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VieCuri Medical Centre
Subchondral Insufficiency Fracture
Bio-Integrative, Fiber-Reinforced Kneebar for Treating Subchondral Insufficiency of the Knee
The OSSIOfiber® Trimmable Fixation Nails are indicated for maintenance of alignment and fixation of bone fractures, osteotomies, arthrodesis and bone grafts in the presence of appropriate additional immobilization (e.g., rigid…
- Trial name
- NCT06138548
- Testing
- Ossiofiber® Trimmable Fixation Nail
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Bone Fractures
AI-Assisted Fracture Detection in Emergency Radiography
This study evaluates whether artificial intelligence (AI) can support doctors who interpret X-rays for suspected fractures in emergency care.
- Trial name
- FAIR (NCT06754137)
- Testing
- BoneView AI-Assisted Radiograph Interpretation
- Where
- 3 sites in Austria, Germany
- Volunteers
- 1,667 people
- Sponsor
- Salzburger Landeskliniken
Osteoporosis, Osteoarthritis
OSTEOMICS: Identifying Regulators of Bone Homeostasis
Diseases of bone associated with ageing, including osteoporosis (OP) and osteoarthritis (OA), reduce bone mass, bone strength and joint integrity.
- Conditions
- Osteoporosis, Osteoarthritis, Bone Diseases, Bone Fracture
- Trial name
- OSTEOMICS (NCT05732870)
- Testing
- Relevant orthopaedic surgery
- Where
- 8 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Relation Therapeutics
Osteopenia, Osteoporosis
Calcium-Rich Food Versus Calcium Carbonate for Bone Health
This study will compare adherence, tolerability, safety, and treatment satisfaction between a calcium-rich food and a traditional calcium carbonate supplement in women ages 40 to 90 who are at increased risk for osteoporosis.
- Conditions
- Osteopenia, Osteoporosis, Bone Health in Perimenopausal Women, Menopause Related Conditions
- Trial name
- NCT07763509
- Testing
- 500 mg calcium from milk-derived minerals, Calcium Carbonate 500 MG
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Cornell University
Bone Fractures
Ultrasound Assessment of Pediatric Fracture Healing With the PLUS Score
This observational study investigates whether ultrasound can safely and accurately monitor the healing of bone fractures in children, comparing it to standard X-rays.
- Trial name
- USG-FRACTHEAL (NCT07755787)
- Testing
- Point-of-care ultrasound
- Where
- Czechia
- Volunteers
- 1,200 people
- Sponsor
- University Hospital Hradec Kralove
Patients Undergoing Operative Fixation of Long Bone Fractures Within the Community Medical Centers System
Prospective Study: TXA, Anticoagulant, Orthopaedic Trauma
Tranexamic acid, an anti-fibrinolytic agent, is commonly given after induction of general anesthesia in patients undergoing hip and knee arthroplasty.
- Trial name
- TXA (NCT07116395)
- Testing
- Tranexamic Acid (TXA)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Arbi Nazarian, MD
Leg Injuries, Fracture
Soft Part Management for Surgical Fractures of the Lower Limb
The assessment consists in comparing corticoids injection versus placebo in surgery of lower limb fractures The aim of study is to assess (state cutaneous, efficacy, safety) corticoids injection on a prospective, randomized…
- Conditions
- Leg Injuries, Fracture, Edema
- Trial name
- ICOMI (NCT03915223)
- Testing
- leg fracture
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pilon Fractures, Fractures
Surgery of the Pilon Fractures
The assessment consists in comparing the osteosynthesis plate with minimally invasive technique versus open reduction and internal fixation.
- Conditions
- Pilon Fractures, Fractures, Bone, Leg Injuries
- Trial name
- MICOPIL (NCT03367169)
- Testing
- minimally invasive method, open reduction method
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Clermont-Ferrand
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Bone Fractures
Naringenin Supplementation in Bone Fracture Patients
Fractures of the lower extremities represent a significant proportion of injuries sustained by polytrauma patients, with a notable association with prolonged hospitalization, chronic disability, and impaired physical functioning.
- Trial name
- NCT06612762
- Testing
- The daily ingestion of capsules containing naringenin
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Fracture
Multimodal Decision Support for Perioperative Risk Stratification in Older Adults Undergoing Surgery for Fracture
The goal of this observational study is to establish a standardized multicenter cohort and develop and validate clinically interpretable models for perioperative risk stratification, brain-state risk prediction, objective pain…
- Trial name
- NCT07736469
- Volunteers
- 4,000 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Chronic Kidney Diseases, Bone Loss
Bone in CKD Alkali Response (BICARb Pilot Trial)
The goal of this clinical trial is to test whether potassium citrate improves skeletal health in adults and children with chronic kidney disease.
- Trial name
- BICARb (NCT05918029)
- Testing
- Potassium Citrate Extended Release Oral Tablet, Potassium Citrate and Citric Acid Oral Solution
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Albert Einstein College of Medicine
Elbow Fractures
Effect of CHRIST on Function and ROM in Post Fracture rehabIlitation
The main objective of the study is to find the effects of comprehensive hand repetitive intensive strength training on range of motion and function in post fracture rehabilitation to answer the question such as Does CHRIST…
- Trial name
- NCT07729878
- Testing
- Comprehensive Hand Repetitive Intensive Strength Training
- Where
- Pakistan
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Bone Fractures, Long Bone Fracture
Diagnostic Accuracy and Operational Efficiency of Point-of-Care Ultrasound (POCUS) in Long Bone Fractures: A Brazilian Multicenter Study
The purpose of this study is to evaluate the diagnostic accuracy and operational efficiency of Point-of-Care Ultrasound (POCUS) for identifying long bone fractures in the emergency department.
- Trial name
- POCUS-BONE BR (NCT07728227)
- Volunteers
- 260 people
- Sponsor
- University of Sao Paulo
Osteoporosis, Osteopenia
Finding the Optimal Resistance Training Intensity For Your Bones
Osteoporosis is a bone disease that can result in fractures, disability and an increased risk of premature death. Exercise is recommended for fall and fracture prevention, but health care professionals often recommend walking or…
- Trial name
- NCT05541432
- Testing
- Supervised strength training (group 1), Supervised strength training (group 2), Home exercise
- Where
- 3 sites in Canada
- Volunteers
- 324 people
- Sponsor
- University of Waterloo
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)
Can we 'Hear' Femoral Neck Fractures? Ultrasound Guided Diagnosis of Femoral Neck Fractures
Hip (femoral neck and pertrochanteric) fractures account for a significant part of Emergency Department (ED) visits after trauma.
- Trial name
- CHEFF (NCT06765083)
- Testing
- POCUS of the hip
- Where
- Netherlands
- Volunteers
- 146 people
- Sponsor
- Frisius Medisch Centrum