Clinical trials: Bone Density
Eosinophilic Esophagitis
Eosinophilic Esophagitis Steroid Safety Study
This observational study will follow pediatric patients with eosinophilic esophagitis who are scheduled to begin topical steroid treatment, from the initiation of treatment longitudinally to determine the safety profile of the…
- Trial name
- EESY (NCT04416217)
- Where
- 4 sites in Greece, Israel and 1 more
- Volunteers
- 55 people
- Sponsor
- Rabin Medical Center
Osteoarthritis of Hip
Bone Mineral Changes Around Stemless and Stemmed Cementless Femoral Components
The purpose of this study is to determine if there is a difference in stress shielding and bone resorption of the proximal femur in two anatomical stem total hip designs.
- Trial name
- NCT00957970
- Testing
- Stemless femoral component, IPS, Depuy cementless femoral stem
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Ewha Womans University
Contraception, Change in Bone Mineral Density
Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females
This study will be in two parts, Part A and Part B. The primary objective of Part A is to evaluate the contraceptive efficacy of LPRI-CF113.
- Trial name
- NCT05461573
- Testing
- Drospirenone
- Where
- 47 sites in United States, Canada
- Volunteers
- 1,542 people, healthy volunteers welcome
- Sponsor
- Insud Pharma
Postmenopausal Osteoporosis
Impact of Ultraviolet Radiation on Bone Density and Muscle Strength in Postmenopausal Women
70 postmenopausal women, aged 50 to 60, who are vitamin D deficient and diagnosed with osteoporosis or osteopenia with T score of DEXA of lumbar spine (L1 to L4) was less than or equal -1 and their body mass index between 25 and…
- Trial name
- NCT05650437
- Testing
- Ultraviolet Radiation, Aerobic exercise, Vitamin D supplementation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Iron Deficiency, Iron Deficiency Anemia (IDA)
Collegiate Athlete Study
The purpose of this study is to determine what percentage of Black collegiate athletes have low energy availability. It will also determine the percentage of Black collegiate athletes who have iron deficiency, suboptimal or low…
- Conditions
- Iron Deficiency, Iron Deficiency Anemia (IDA), Vitamin D Deficiency, Vitamin D Insufficiency
- Trial name
- NCT07631312
- Testing
- Iron and Vitamin D Deficiencies Correction
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Sedentary Lifestyle, Postmenopausal Women
Health Benefits of a 6-month Brisk Walking Program in Sedentary Postmenopausal Women
Community-dwelling women aged 55 or over are recruited at public meetings aimed at promoting physical activity in postmenopausal women.
- Trial name
- ACTIMARCH (NCT02094144)
- Testing
- Brisk walking program, physical activity habit
- Where
- France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
T2DM (Type 2 Diabetes Mellitus), Low-level Laser Therapy
Effect of Low-level Laser Therapy on Type II Controlled Diabetic Patients After Dental Implant Insertion
This study aimed therefore to evaluate bone density (BD) and OPG levels in the peri-implant crevicular fluid (PICF) in lased controlled type II Diabetes Mellitus (T2DM) patients versus non-lased T2DM patients.
- Conditions
- T2DM (Type 2 Diabetes Mellitus), Low-level Laser Therapy, Bone Density Increased
- Trial name
- NCT05279911
- Testing
- low-level laser therapy (LLLT)
- Where
- 5 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Sinai University
Hip Arthroplasty
Stem Cells Predicting Orthopedic Outcomes
This is a pilot study to provide preliminary data of the association between bone mineral denity adjacent to acetabular implants, as measured by quanitative computed tomography (QCT), at least 2 years post Total Hip Arthoplasty…
- Trial name
- NCT01366911
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
End-Stage Renal Disease, Hemodialysis
Effects of Lowering Dialysate Calcium Level on Progression of Coronary Artery Calcification and Bone Histomorphometry
The high rate of cardiovascular complications in the dialysis population cannot be explained by traditional cardiovascular risk factors.
- Trial name
- NCT00297219
- Testing
- Low dialysate calcium, high dialysate calcium
- Where
- 3 sites in United States, Turkey (Türkiye)
- Volunteers
- 457 people
- Sponsor
- Ege University
Bone Giant Cell Tumor
Reduced Dose-density of Denosumab for Unresectable GCTB
This study is a multi-center, multi-national, open label, single arm phase 2 study of single-agent denosumab. The objective of the trial is to evaluate the risk versus benefit of denosumab in maintenance setting in patients…
- Trial name
- REDUCE (NCT03620149)
- Testing
- Denosumab 120 MG/1.7 ML Subcutaneous Solution [XGEVA]
- Where
- 8 sites in Italy, Netherlands and 2 more
- Volunteers
- 2 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Distal Radius Fractures, Poor Bone Quality
The Influence of Local Bone Status on Complications After Surgical Treatment of Distal Radius Fractures
The purpose of this study is to evaluate if poor bone quality increases the risk of specific types of treatment complications in patients with distal radius fractures treated with open reduction and Locking Compression…
- Conditions
- Distal Radius Fractures, Poor Bone Quality, Treatment Complications
- Trial name
- NCT01144208
- Where
- 11 sites in United States, Austria and 4 more
- Volunteers
- 244 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Indicated for EOSedge Imaging
Bone Mineral Density Precision Study
The purpose of this research is to collect medical imaging data to allow for the comparison of bone mineral density measurements from two low-dose x-ray exams.
- Trial name
- NCT06830811
- Testing
- EOSedge imaging
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Alphatec Spine, Inc.
Postemenopusal Women With Osteopenia
Effect of Raloxifene Plus Cholecalciferol and Cholecalciferol Alone on the Bone Mineral Density in Postmenopausal Women With Osteopenia
Osteoporosis is a very strong predictor of fractures with low BMD, but more than half of osteoporotic fractures actually occur in the osteopenic patient group.
- Trial name
- NCT05386784
- Testing
- Raloxifene plus cholecalciferol, Cholecalciferol
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Yonsei University
Prostatic Neoplasms
Androgen Deprivation Therapy on Bone Mineral Density Change in Prostate Cancer Patients
Androgen deprivation therapy (ADT) is a mainstay of prostate cancer treatment to improve overall survival for intermediate- and high-risk localized disease as well as metastatic disease.
- Trial name
- NCT04248621
- Testing
- Leuprorelin, Goserelin, Triptorelin
- Where
- 10 sites in South Korea
- Volunteers
- 164 people
- Sponsor
- Wonju Severance Christian Hospital
Prevention of BMD Loss After THR, Serum Markers of Bone Turnover
Prevention of Periprosthetic Bone Loss After Total Hip Replacement by Annual Bisphosphonate Therapy
Periprosthetic bone loss caused by stress-shielding effect, a phenomenon of bone atrophy under mechanical unloading after THR implantation, further compromises the longevity of implant.
- Conditions
- Prevention of BMD Loss After THR, Serum Markers of Bone Turnover, Functional Outcomes
- Trial name
- NCT02838121
- Testing
- Aclasta
- Where
- Taiwan
- Volunteers
- 62 people
- Sponsor
- Mel Shiuann-Sheng Lee
Spinal Muscular Atrophy Type 3, Ambulatory Spinal Muscular Atrophy
Gait and Bone Health in SMA
The objective of this study is to understand how spatiotemporal and kinetic gait parameters are associated with bone health in pwSMA who are receiving DMT.
- Trial name
- NCT07400198
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Jacqueline Montes
Anterior Mandibular Fracture
Comparing Bone Healing in Jaw Fractures Fixed With Herbert Screws Versus 3D Miniplates
the goal of this clinical trial is to compare two methods of fixing fractures in the front part of the jaw (mandible): second-generation Herbert screws and 3-dimensional miniplates.
- Trial name
- herbert screw (NCT07826416)
- Testing
- headless compression screw, 3D mini plates
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoporosis, Osteopenia, Renal Transplant Recipient
Alendronate Versus Denosumab in Kidney Transplant Patients
The management of bone disease has often been neglected post-transplantation, when the clinical focus is on allograft function and immunological sequelae.
- Trial name
- NCT04169698
- Testing
- Denosumab 60 mg/ml [Prolia], Alendronate 70Mg Tab
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Anorexia Nervosa, Osteopenia
IGF-1 and Bone Loss in Women With Anorexia Nervosa
Anorexia nervosa is an eating disorder that can cause thinning of the bones (a decrease in bone density). A significant decrease in bone density is called osteopenia or osteoporosis.
- Conditions
- Anorexia Nervosa, Osteopenia, Osteoporosis
- Trial name
- NCT01406444
- Testing
- rhIGF-1, Risedronate
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Massachusetts General Hospital
Psychiatry
Comparison of Bone Mineral Density Changes During Tx With Risperidone or Aripiprazole in Adolescents
This study examines if the use of antipsychotic medications might contribute to an interruption in bone mineral development and/or a reduction in bone mineral content in adolescents.
- Trial name
- NCT00573716
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Creighton University