Clinical trials: Body Weight Changes
Stage IV Non-small Cell Lung Cancer, Cachexia
Ruxolitinib for Cancer Cachexia
To assess toxicity with use of Ruxolitinib in NSCLC cachexia patients; to associate levels of JAK/STAT signaling in blood, adipose, and muscle pre- and post-ruxolitinib treatment with changes in cachexia and anorexia.
- Trial name
- NCT04906746
- Testing
- Identify any dose-limiting toxicity (DLT) when ruxolitinib is administered to NSCLC cachexia patients.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tu Dan
Obesity, Childhood
Improving Childhood Obesity-Related Behavior Change Through Better Risk Communication
One-third of American children are overweight or obese, leading to an increased risk for cardiovascular disease (CVD), early mortality, and other risks throughout their lifespan relative to normal weight children.
- Trial name
- NCT03074929
- Testing
- Novel risk communication
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Gestational Weight Gain, Obesity
A Weight Maintenance Program Promoting Fat Loss in Pregnancy in Women With Obesity
The aims of this randomized controlled trial are to determine the effects of a lifestyle program that supports weight maintenance and fat mass loss during pregnancy in women with obesity on changes in 1) maternal weight, fat…
- Trial name
- Healthy Mamas (NCT04731688)
- Testing
- Weight Maintenance Group
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
Protein Eating Patterns and Weight Loss
The purpose of this study is to determine the effects of daily protein intake patterns on body composition and eating behaviors during weight loss.
- Trial name
- NCT03202069
- Testing
- Even protein, Skewed protein
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Body Composition, Obesity
Efficacy of Liquid Versus Powder Protein Supplementation to Optimize Protein Intake After Bariatric Surgery
The goal of this randomized control trial is to compare the effect of a liquid formula rich in nutrients and low in calories (supplement) with the progressive diet with conventional foods that we usually recommend in patients…
- Conditions
- Body Composition, Obesity, Protein Supplementation, Bariatric Surgery Candidate
- Trial name
- NCT06267677
- Testing
- High protein liquid formula
- Volunteers
- 50 people
- Sponsor
- Hospital Clinic of Barcelona
Dietary Habits, Obesity
Intervention, Dietary, Diabetes, Pregnancy
The aim of this rct -study is to explore the effect of a dietary intervention for overweight (body maas index BMI≥25) and obese (BMI≥30) pregnant women on gestational weight gain and the prevalence of gestational diabetes.
- Conditions
- Dietary Habits, Obesity, Gestational Diabetes, Gestational Weight Gain
- Trial name
- IDDP (NCT04690907)
- Testing
- Dietary intervention
- Where
- 2 sites in Finland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Ductal Carcinoma In Situ, Breast Cancer
Effects of Diet and Exercise on Ductal Carcinoma in Situ
This pilot/feasibility trial seeks to explore whether an acute bout of negative energy balance prior to surgery affects biomarkers of neoplasia.
- Trial name
- DCIS (NCT02224807)
- Testing
- Active Comparator: Progressive Resistance Training (PRT) and a healthy diet, Experimental: PRT and a healthy diet, plus weight loss
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Alabama at Birmingham
Overweight and Obesity
Predictors of Lorcaserin-Induced Weight Loss
This two-phase study aims to explore ways to predict who will respond well to the weight loss drug lorcaserin and to understand the mechanisms that develop which limit drug efficacy.
- Trial name
- NCT03353220
- Testing
- Belviq
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity
Program for the Promotion of Physical Exercise and Healthy Eating Among Population of Pakistani Origin With Obesity
This randomized control trial aims to evaluate the effectiveness of a culturally and linguistically adapted nutrition education and physical exercise program on lifestyle (diet and exercise), metabolic parameters, and fat content…
- Trial name
- PEFAS (NCT07009054)
- Testing
- Nutrition Education and Exercise, Usual Care Group
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Germans Trias i Pujol Hospital
Obesity
Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study
This research study is being performed to find out if a new device, AspireAssist Aspiration Therapy System, can help people with obesity to lose weight without causing too many side effects.
- Trial name
- PATHWAY (NCT01766037)
- Testing
- Aspiration Therapy (AspireAssist), Lifestyle Therapy
- Where
- 10 sites in United States
- Volunteers
- 171 people
- Sponsor
- Aspire Bariatrics, Inc.
Weight Loss, Overweight
Rethinking Eating and FITness for Men
The purpose of this study is to test the effect of a new three-month behavioral weight loss program among adult men. Weight will be measured at three and six months post randomization.
- Trial name
- REFIT (NCT01843595)
- Testing
- REFIT Intervention
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Weight Loss
The Undernourished Patient: Prevention and Treatment
The purpose of this study is to determine whether a nutrition intervention during a rehabilitation stay followed by nutritional advice after discharge, can improve the nutritional status of the patients after 3 months.
- Trial name
- NCT01632072
- Testing
- Nutritional support
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- University of Oslo
Obesity, Weight Loss
The Big Breakfast Study
This weight loss study will investigate the impact of diet composition and meal size (large breakfast meals and smaller evening meals) on body weight, energy balance and eating behaviour, by altering calorie (meal) distribution.
- Trial name
- NCT03077295
- Testing
- High Fibre, High Protein
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Gestational Weight Gain
My Baby My Move A Community Wellness Intervention
My Baby, My Move+ (2019-2021) is a peer-led wellness intervention which aims to reduce excessive gestational weight gain (EGWG) by targeting prenatal physical activity, mood, and sleep quality.
- Trial name
- MBMM+ (NCT04294095)
- Testing
- My Baby My Move +, Control
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Colorado, Denver
Overweight and Obesity
Tailored Lifestyle Intervention in Obese Adults Within Primary Care Practice - Choose to Lose
The primary objective of the study is to evaluate the effectiveness of tailored lifestyle intervention in primary care by comparing changes in the primary measure of weight and body mass index (BMI) and secondarily: physical…
- Trial name
- CTL (NCT01542671)
- Testing
- Intervention, Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Obesity Type 2 Diabetes Mellitus, Obesity & Overweight
Eating Behaviour Before, During, and After Obesity Medication
This study will examine how eating behaviour changes during the first 18 months of treatment with obesity medications in patients attending the St Vincent's Healthcare Group obesity service.
- Trial name
- NCT07636395
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University College Dublin
Obesity
Dairy Intervention in People With Obesity
Obesity is associated with increased morbidity and mortality, but weight reduction is difficult to achieve. In this randomized controlled trial we will include 120 obese subjects.
- Trial name
- DIPO (NCT04154475)
- Testing
- yogurt diet, dairy diet, standard diet
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Overweight
Treating Obesity in Underserved Overweight Populations
Obesity has reached epidemic proportions with nearly two-thirds of the US population either overweight or obese. Thus, novel strategies that both improve weight loss maintenance and are accessible to those most in need are the…
- Trial name
- NCT00373230
- Testing
- telemedicine
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Temple University
Obesity, Weight Gain
Preventing Obesity in Military Communities, Adolescents
This research study is aimed at the prevention of excessive weight gain in female military dependents at high risk for adult obesity.
- Conditions
- Obesity, Weight Gain, Disordered Eating, Eating Disorder
- Trial name
- POMC-A (NCT02334202)
- Testing
- Interpersonal Psychotherapy-Weight Gain, Health Education
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Overweight and Obesity
Weight Loss Goals and Satisfaction Survey
The goal of this observational survey pilot study is to learn how 3D visualization tools (i.e., personalized avatars) influence weight loss goals, satisfaction, confidence, and commitment compared to numerical weight outcomes in…
- Trial name
- NCT07541872
- Testing
- Personalized 3D Body Visualization
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center