Clinical trials: Blood Pressure Variability
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 1 of 7)
NOTE: This is the first of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882516
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Vagus Nerve Stimulation, Autonomic Nervous System
Frequency-Dependent Effects of Auricular Vagus Nerve Stimulation on Autonomic and Cardiovascular Parameters
This randomized, sham-controlled, crossover study investigates the acute autonomic effects of transcutaneous cervical vagus nerve stimulation (tcVNS) applied at five different frequencies (0 Hz/sham, 10 Hz, 25 Hz, 50 Hz, 100 Hz)…
- Conditions
- Vagus Nerve Stimulation, Autonomic Nervous System, Heart Rate, Blood Pressure
- Trial name
- AVNS-DRC (NCT07274332)
- Testing
- Pulsetto FIT™ - tcVNS 10 Hz, Pulsetto FIT™ - tcVNS 25 Hz, Pulsetto FIT™ - tcVNS 50 Hz
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Anxiety, Heart Rate Variability (HRV)
Anxiety and Physiological Responses in Ambulatory Surgery
This study aims to investigate the effects of music intervention on subjective anxiety and physiological indicators, including heart rate, blood pressure, and heart rate variability, in first-time ambulatory surgery patients, and…
- Conditions
- Anxiety, Heart Rate Variability (HRV), Heart Rate, Blood Pressure
- Trial name
- NCT07476820
- Testing
- Self-selected Music intervention, Fixed-music Music intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Da-Yeh University
Cardiovascular Diseases, Hypertension
The Galway Sea Swimmers Study
Cardiovascular disease (CVD) is the leading cause of death worldwide. Hypertension is a well-established risk factor for the development of CVD.
- Trial name
- GS3 (NCT04290637)
- Testing
- Cold-water sea swimming, No cold-water sea swimming
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Postmenopausal Flushing, Cardiovascular Risk Factor
Hot Flash as a Marker of Cardiovascular Risk in Recent Postmenopause: Effects of Non-hormonal Treatments
Hot flashes, vasomotor symptoms that affect many postmenopausal women, are associated with cardiovascular disease and endothelial dysfunction.
- Conditions
- Postmenopausal Flushing, Cardiovascular Risk Factor, Endothelial Dysfunction
- Trial name
- NCT03149419
- Testing
- Paroxetine
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Healthy Participants, Healthy Young Adults
Foam Rolling, Blood Pressure and Range of Motion
Foam rolling (FR) is a technique involving the application of external pressure to muscles and connective tissues using different devices (e.g.
- Trial name
- NCT07433543
- Testing
- Cervical foam rolling
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Hypertension, Vitamin D Deficiency
The Impact of Vitamin D Supplementation in Hypertensive Vitamin D Deficient Patients.
This study will assess the impact of Vitamin D supplementation on hypertensive patients with Vitamin D deficiency, it will also investigate the relationship between serum Vitamin D, irisin levels, blood pressure, and heart rate…
- Trial name
- NCT06645041
- Testing
- Vitamin D (Cholecalciferol )
- Where
- 3 sites in Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani
Hypotension,Controlled
Correlation Analysis of the Effects of Management Pressure Goals and Control Volume Goals in Patients in Spinal Surgery
The investigators study 160 patients undergoing spinal surgery.Participants will be randomly divided into study group and control group.The study group will receive controlled hypotension by nitroglycerin and be divided into 3…
- Trial name
- NCT03917004
- Testing
- Nitroglycerin
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Liang Bing
Stress, Pituitary-Adrenal System
Modulating Stress-Reactivity by Real-Time Multimodal Functional Neuroimaging Based Neurofeedback
The overall goal of the outlined study is to establish a Real-Time (RT) functional Magnetic Resonance Imaging (fMRI) Neurofeedback (NF) (RT-fMRI-NF) protocol aiming at modulating neural, endocrine, and subjective reactivity to…
- Trial name
- NCT02560233
- Testing
- Contingent RT-fMRI-NF
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 2 of 7)
NOTE: This is the second of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882529
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Aging, Autonomic Nervous System
Effects of a Smart Circuit Exercise Program on Health Outcomes in Community-Dwelling Older Adults
This study was conducted in collaboration with a community-based retirement facility to evaluate the clinical effectiveness of a smart, technology-assisted circuit exercise intervention for community-dwelling older adults.
- Conditions
- Aging, Autonomic Nervous System, Hemodynamics
- Trial name
- NCT07790263
- Testing
- Smart Circuit Exercise Program
- Where
- Taiwan
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Healthy, Healthy Participants
Neck Static Stretching Acutely Reduces Blood Pressure Through Reduction of Tissue Stiffness
Stretching is usually done to improve flexibility and joint movement. Recent research suggests that stretching may also affect the body's heart and blood vessels.
- Conditions
- Healthy, Healthy Participants, Healthy Subjects, Healthy Volunteers
- Trial name
- NCT07197047
- Testing
- Neck static stretching
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Healthy
Validation Study of Selfie Technology for Assessment of Vital Signs
The aim of this study is to compare accuracy of DocMe, a video technology developed by DocMe Health Technologies, with previously validated medical devices used for measurements of heart rate, heart rate variability, respiratory…
- Trial name
- NCT04688112
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- DocMe Technologies Ltd
Healthy
The Effects of Single-Pulse Transcranial Magnetic Stimulation on the Autonomic Nervous System in Healthy Adults
The purpose of this study is to determine the effects of TMS on the ANS. The investigator will determine whether single-pulse TMS of the primary motor cortex in the dominant hemisphere in healthy, young adults will affect 1)…
- Trial name
- NCT02833220
- Testing
- Single-Pulse Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy
Acute Vascular Response To Meals Varying In Glycemic Index And Glycemic Load
This study examines the effects of carbohydrate type (high- or low-Glycemic Index (GI)) and amount (high- or low-Glycemic Load (GL)) have on blood glucose levels, blood pressure and arterial stiffness in healthy individuals.
- Trial name
- HILO (NCT01883700)
- Testing
- Boiled Pasta, Boiled Chickpeas with Oil, Instant Mashed Potatoes
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Cardiac Autonomic Function, Hemodynamic Changes
Effects of Post-Match Foam Rolling, Static Stretching, and Passive Rest on Acute Cardiac-Autonomic, Hemodynamic, and Neuromuscular Recovery in National Wrestlers
This study looks at three common ways athletes recover after a wrestling match: foam rolling, static stretching, and resting. We want to learn which method helps the body recover better in the short time that athletes often have…
- Conditions
- Cardiac Autonomic Function, Hemodynamic Changes, Neuromuscular Adaptations, Exercise and Recovery
- Trial name
- NCT07305506
- Testing
- Foam Rolling, Static Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ali Kamil GÜNGÖR
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 5 of 7)
NOTE: This is the fifth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919189
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Hypertension
High-Intensity Interval Versus Moderate-Intensity Continuous Water Based Exercise in Hypertensive Older Individuals
This study will investigate the acute and chronic effects in hemodynamic and autonomic variables to high-intensity interval versus moderate-intensity continuous heated water-based exercise in older individuals with hypertension.
- Trial name
- HExOLD (NCT04126785)
- Testing
- High Intensity Interval Exercise in Heated Water-Based, Continuous Moderate Exercise in Heated Water-Based, Control Group
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Autonomic Nervous System Imbalance, Blood Pressure
Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators
An intervention study to assess the short-term cardiovascular effects of reducing personal air pollution exposure by wearing particulate filtering respirators.
- Conditions
- Autonomic Nervous System Imbalance, Blood Pressure, Inflammation, Vasoconstriction
- Trial name
- NCT02238028
- Testing
- Wear respirator
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Fudan University