Clinical trials: Blood Pressure Disorders
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Obesity (Disorder), Weight Change
Impact of Semaglutide Withdrawal on Cardiometabolic Profile and Physiology of Energy Balance: Recovery Effects After Semaglutide Termination
Semaglutide is a medication from the class of drugs called glucagon-like peptide-1 agonists that promote weight loss. There is little clinical data on the best strategy to achieve weight maintenance following weight reduction…
- Conditions
- Obesity (Disorder), Weight Change, Blood Pressure Monitoring, Appetite Regulation
- Trial name
- REST (NCT07294950)
- Testing
- Gradual dose reduction of semaglutide, Abrupt cessation of semaglutide
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- Mount Sinai Hospital, Canada
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Cardiovascular Abnormalities, Arterial Blood Pressure
Multicenter Study on Cardiovascular and Metabolic Complications in Patients With Biochemically Silent Pheochromocytomas and Paragangliomas
The aim of the study is to characterise the cardiovascular and metabolic complications pre- and post-surgery of patients with biochemically negative PPGL and to compare them with normal individuals and patients with secreting…
- Conditions
- Cardiovascular Abnormalities, Arterial Blood Pressure, Heart Rate, Congestive Heart Failure Chronic
- Trial name
- NCT07316075
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laikο General Hospital, Athens
Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease
Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers
People who experience repeated bouts of circadian misalignment, such as shift workers, are at higher risk of cardiovascular disease (CVD) and Type 2 diabetes (T2D) compared to daytime workers.
- Conditions
- Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease, Insulin Sensitivity, Blood Pressure
- Trial name
- SHINE (NCT06550115)
- Testing
- Time-restricted eating, Control eating
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Insomnia, Insomnia Chronic
Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia
Individuals who have insomnia with short sleep duration (ISS) differ from individuals who have insomnia with normal sleep duration (INS) in terms of health risks (i.e., hypertension) and treatment response.
- Conditions
- Insomnia, Insomnia Chronic, Insomnia, Primary, Blood Pressure
- Trial name
- NCT06281756
- Testing
- Cognitive Behavioral Treatment for Insomnia (CBT-I), Trazodone
- Where
- 4 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Milton S. Hershey Medical Center
White Coat Hypertension, Hypertension
Virtual Reality as a Tool to Lower Blood Pressure and Anxiety in Clinic Settings
This clinical trial aims to evaluate whether a calming virtual reality (VR) experience can reduce office blood pressure (OBP) and anxiety in adults undergoing ambulatory blood pressure monitoring (ABPM) at Mayo Clinic in Florida.
- Conditions
- White Coat Hypertension, Hypertension, Blood Pressure, Anxiety
- Trial name
- NCT06960057
- Testing
- Virtual Reality Exposure
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Mayo Clinic
Diabetes, Cholesterol
Interprofessional Pharmacogenomics (IPGx) Registry and Repository
This program collects genetic and health information to help doctors choose the right medications for patients.
- Conditions
- Diabetes, Cholesterol, Cancer, Blood Pressure Disorders
- Trial name
- IPGx Registry (NCT06726590)
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Texas A&M University
Hypertension, Renal Denervation
Renal Arterial Denervation in Sympathetic Dysautonomia
The RANSOM registry is considered as a collection of data with the ultimate purpose of gathering information about the effect of renal denervation in patients of the investigator's center and evaluating the results within the…
- Conditions
- Hypertension, Renal Denervation, Increased Variability, Blood Pressure Disorders
- Trial name
- RANSOM (NCT04314557)
- Testing
- Renal denervation
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- St Carlos Hospital, Madrid, Spain
Primigravida Women, Music Therapy
Effect of Music and Warm Foot Bath Therapy on Pregnancy-Related Anxiety, Blood Pressure and Quality of Life
Study Title: The Effects of Music Therapy and Warm Foot Bath on Pregnancy-Related Stress, Blood Pressure, and Quality of Life in Low-Risk Primigravida Women Brief Summary: This randomized controlled trial investigates the impact…
- Conditions
- Primigravida Women, Music Therapy, Blood Pressure Monitoring, Quality of Life
- Trial name
- NCT07064733
- Testing
- Music Therapy, warm water foot bath therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Depression, Anxiety
Income Volatility and Mental Health, Full Experiment
Income instability is a defining aspect of the lives of the poor, who also disproportionately suffer from poor mental and physical health.
- Conditions
- Depression, Anxiety, Blood Pressure
- Trial name
- NCT06988410
- Testing
- Work opportunities
- Where
- Ghana
- Volunteers
- 2,267 people, healthy volunteers welcome
- Sponsor
- Cornell University
Preeclampsia, Blood Pressure Check (Hypertension Screening)
EFFECT OF BLOOD PRESSURE MEASUREMENT IN DIFFERENT POSITIONS ON BLOOD PRESSURE VALUES AND ANXIETY LEVELS IN PREGNANT WOMEN WITH PREECLAMPSIA
Aim: This study examined the effects of blood pressure measurement in different positions on diastolic and systolic blood pressure values and anxiety levels in pregnant women diagnosed with preeclampsia.
- Trial name
- PREECLAMPSIA (NCT06898567)
- Testing
- Right Lateral Position, Left Lateral Position, Semi Fowler Position (45° Fowler)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Istanbul University - Cerrahpasa
Anxiety, Depression Anxiety Disorder
High Intensity Training for Patients with Anxiety
The aim of the current project is to examine the effects of high intensity exercise (by using 1x4 intervals) to reduce symptoms of anxiety in patients in mental health care.
- Conditions
- Anxiety, Depression Anxiety Disorder, Blood Pressure Check (Hypertension Screening)
- Trial name
- NCT06881758
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- University Hospital of North Norway
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Hemodynamic Instability, Blood Pressure, Low
Hemodynamic OptimizaTion in Sitting POsition Surgery Trial
Intraoperative hypotension (MAP <65 mmHg) in patients undergoing general anesthesia is a notable risk factor for the development of post-operative complications including acute kidney injury (AKI), myocardial injury, stroke and…
- Conditions
- Hemodynamic Instability, Blood Pressure, Low, Orthopedic Disorder
- Trial name
- HOTSPOT (NCT05143632)
- Testing
- ClearSight
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Non Communicable Diseases, Blood Pressure
Evaluation of the Ambuja Cement Foundation Noncommunicable Disease Program in Bathinda District of Punjab, India
This is an academic evaluation of a program being implemented by the Ambuja Cement Foundation (ACF). The aim of the evaluation is to determine the effect of the ACF noncommunicable disease (NCD) program on (1) fasting blood…
- Conditions
- Non Communicable Diseases, Blood Pressure, Behavior, Health, Blood Glucose, High
- Trial name
- NCT04827615
- Testing
- Ambuja Cement Foundation's Non Communicable Disease Program
- Where
- India
- Volunteers
- 11,322 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Cardiovascular Diseases, Blood Pressure Disorders
Effect of Korean Red Ginseng Extract on Blood Flow in Healthy Adults
The objectives of this clinical trial are to 1) determine the effect of the TP compared to placebo on blood flow and platelet aggregation, 2) to determine the effect of the TP on cardiovascular health compared to a placebo and 3)…
- Conditions
- Cardiovascular Diseases, Blood Pressure Disorders, Vasodilation, Platelet Aggregation
- Trial name
- NCT06236243
- Testing
- Korean Red Ginseng Extract Powder 120 mg/tablet, Korean Red Ginseng Extract Powder 500 mg/tablet
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Korea Ginseng Corporation
Blood Pressure Check (Hypertension Screening), Heart Rate
Effects of Sleep Body Temperature on Body Composition
This will be a crossover controlled trial designed to recruit 40 participants, who will be divided into two groups of 20 subjects each. The participants will be randomly assigned to either Group A or Group B.
- Conditions
- Blood Pressure Check (Hypertension Screening), Heart Rate, Aldosterone Disorder
- Trial name
- NCT06648109
- Testing
- Electric Blanket
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jinan University Guangzhou
Transgender, Gender Identity
Effects of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Women
This study will examine markers of vascular endothelial function (vascular health) and metabolic profiles in younger versus older transgender women (people who were assigned male at birth but whose gender identity is female).
- Conditions
- Transgender, Gender Identity, Vascular Stiffness, Vascular Inflammation
- Trial name
- NCT04066283
- Testing
- No intervention
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver