Clinical trials: Blood Glucose, open to volunteers
Prediabetes, Brain Insulin Sensitivity
Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals
Primary aim of the study is to assess the effect of 12-week daily avocado consumption on cerebral blood flow and markers of cardio- and vascular health in both, the periphery and the brain, in pre-diabetic individuals with…
- Conditions
- Prediabetes, Brain Insulin Sensitivity, Cerebral Blood Flow, Satiety and Food Intake
- Trial name
- NCT07752225
- Testing
- Avocados
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Maastricht University Medical Center
Glucose, High Blood
Dose Response Study of Transdermal Human Insulin in Patients
A 21-Day open label study of transdermally delivered human insulin in Type 2 Diabetics as measured by response of down modulation of glucose after dosing of Insulin as compared to historic patient response to injected insulins.
- Trial name
- LEVPS (NCT05159453)
- Testing
- Human Insulin, Finger-actuated, Metered Pump Sprayer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Transdermal Delivery Solutions Corp
Healthy Participants
Glycemic/Insulinemic Effects of Fresh Mango as a Sugar Substitute in Realistic Breakfasts.
Large blood sugar and insulin increases after meals high in table sugar are related to risk for diabetes and heart disease. Additionally, large increases in blood sugar may also negatively impact vascular health.
- Trial name
- NCT07045051
- Testing
- Low-Glycemic Breakfast Containing Oats and Mango, High-Glycemic Breakfast Containing Cereal and Mango, Low-Glycemic Breakfast Containing Oats and Table Sugar
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ball State University
Diabetes Mellitus, Type 2
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
This study is being done to look at the effect and safety of different doses of NNC0662-0419 in people living with type 2 diabetes when compared to placebo or semaglutide.
- Trial name
- NCT07415954
- Testing
- NNC0662-0419, Semaglutide
- Where
- 63 sites in United States, Croatia and 8 more
- Volunteers
- 270 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Blood Sugar
Accuracy and Safety of the Syai Tag System for Continuous Glucose Monitoring in Intensive Internal Care Unit
Researchers at the Department of Intensive Internal Medicine and the Department of Endocrinology and Diabetology will conduct a study to verify the accuracy and safety of the new Syai Tag system for continuous glucose monitoring…
- Conditions
- Diabetes Mellitus, Blood Sugar, Sepsis, Critically Ill Intensive Care Unit Patients
- Trial name
- NCT07448805
- Testing
- continuous glucose monitor
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Maribor
Celiac Disease in Children, Diabetes Mellitus, Type I
Auto-antibody Dosage From Blood Spots for Diagnosis of Type 1 Diabetes and Celiace Disease
Early diagnosis of type 1 diabetes and celiac disease is very useful, allows early therapy and prevents deaths from the onset of diabetic ketoacidosis.
- Conditions
- Celiac Disease in Children, Diabetes Mellitus, Type I, Screening
- Trial name
- CELDI (NCT06849622)
- Testing
- Test on blood sample, Test on dried blood sample
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Meyer Children's Hospital IRCCS
Diabetes Mellitus
Feasibility Study to Evaluate an Intravascular Blood Continuous Glucose Sensor
The goal of this early first in man clinical trial is to evaluate the safety of an implantable continuous blood glucose monitoring system in participants with Diabetes Mellitus.
- Trial name
- NCT06764069
- Testing
- Sensor Lead
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Glucotrack
Cardiovascular Abnormalities, Arterial Blood Pressure
Multicenter Study on Cardiovascular and Metabolic Complications in Patients With Biochemically Silent Pheochromocytomas and Paragangliomas
The aim of the study is to characterise the cardiovascular and metabolic complications pre- and post-surgery of patients with biochemically negative PPGL and to compare them with normal individuals and patients with secreting…
- Conditions
- Cardiovascular Abnormalities, Arterial Blood Pressure, Heart Rate, Congestive Heart Failure Chronic
- Trial name
- NCT07316075
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laikο General Hospital, Athens
Blood Pressure, Diabetes
Mitigating the Pro-inflammatory Phenotype of Obesity
The purpose of this study is to examine the hypothesize that 4 weeks of sympathetic nerve activity (SNA) inhibition (oral clonidine) will cause a significant reduction in circulating blood concentrations and endothelial cell…
- Conditions
- Blood Pressure, Diabetes, Obesity, Insulin Resistance
- Trial name
- MAPLE (NCT04934228)
- Testing
- Hydrochlorothiazide 12.5Mg Tab, Clonidine Pill
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Kansas Medical Center
Blood Sugar (Glucose) Control, Postprandial Glucose
Effect of SugarLock® Peanut Skin Extract on Postprandial Blood Glucose Control
The objective of this study is to investigate the effects of pre-meal supplementation with SugarLock® peanut skin extract and white kidney bean extract on reducing or delaying postprandial blood glucose elevation and glycemic…
- Trial name
- NCT07705191
- Testing
- Peanut skin extract, White kidney bean extract, Water
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Type 2 Diabetes
Study Enabling the Collection of Clinical Data Necessary for the Second Phase of Development of the Glycemic Measurement Device by Analysis of Exhaled Air
A pilot study carried out by the company ALPHA-MOS in 2017-19 showed that the analysis of volatile organic compounds contained in exhaled air could reliably predict blood glucose levels.
- Trial name
- BOYDSENSE DATA (NCT06614101)
- Testing
- Exhaled air analysis
- Where
- 2 sites in France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Toulouse
Resistant Starch, Tapioca Starch
Evaluation of VEDAN RT-90 Resistant Cassava Starch for Glycemic Control and Prebiotic Fiber Development in a Human Trial
This study aims to investigate the effects of RT-90 resistant cassava starch on glycemic control using a human dietary trial and to evaluate its potential as a prebiotic fiber supplement.
- Conditions
- Resistant Starch, Tapioca Starch, Prebiotic Fiber, Blood Sugar
- Trial name
- NCT07282496
- Testing
- RT-90 resistant tapioca starch, control group, Commercially available resistant starch
- Where
- Taiwan
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Type 1 Diabetes
Effects of Resistance Exercise on Blood Glucose in Post-menopausal Women With Type 1 Diabetes
Regular physical activity has substantial health benefits in people with type 1 diabetes. The fear of hypoglycemia, both during and after exercise, is a major barrier to exercise in this population.
- Trial name
- NCT05203640
- Testing
- High repetition (HI), Moderate repetition (MOD)
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Type 2 Diabetes
Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification
A Randomized Control Trial (RCT) with 1:1 randomization of adults newly diagnosed with type 2 diabetes (T2D) to Routine Care (RC) and RC + Glycemic Excursion Minimization (RC+GEM); a program that provides RC in addition to…
- Trial name
- GEM (NCT05766735)
- Testing
- Routine Care + Glycemic Excursion Minimization (RC+GEM), Routine Care (RC)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Chiara Fabris, PhD
Hypoglycemia (Diabetic)
Comparing Blood Glucose Control Intraoperative Between Insulin Drip vs. Insulin Boluses Will Provide Valuable Information on the Optimal Method for Achieving Blood Glucose Control Intraoperatively.
Cardiac surgery patients often experience elevated blood glucose levels, which can lead to poor surgical outcomes and increased postoperative complications. Therefore, tight blood glucose control during surgery is important.
- Trial name
- RANDOM-IB (NCT07056088)
- Testing
- Insulin Drip Therapy, Insulin boluses
- Volunteers
- 384 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Pre-biabetes
Effects of Milk Probiotics Intervention on Blood Glucose Control Middle-aged and Elderly People With Pre-diabetes
This study aims to conduct a 8-week probiotics intervention involving for middle-aged and elderly individuals with pre-diabetes, assessing its impact on blood glucose control in comparison to placebo
- Trial name
- NCT06972524
- Testing
- a special probiotics from Mengniu Group, supplemented with milk powder, regular milk powder does not contain any additional supplementation, and the color, flavor, shape, taste, and weight are same with the probiotic milk powder
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Huilian Zhu
Diabetic Kidney Disease, Diabetic Nephropathies
Systemic Immune-Inflammation Index and Platelet Parameters in Diabetic Kidney Disease
Diabetic kidney disease (DKD) is a frequent microvascular complication in individuals with type 2 diabetes mellitus (T2DM) and a major cause of chronic kidney failure worldwide.
- Conditions
- Diabetic Kidney Disease, Diabetic Nephropathies, Type 2 Diabetes Mellitus, Albuminuria
- Trial name
- NCT07773467
- Volunteers
- 120 people
- Sponsor
- Assiut University
Pre Diabetic, Obesity & Overweight
PREdiabetes GLycemic Impact and Data Evaluation
This prospective, randomized controlled trial evaluates whether real-time continuous glucose monitoring (CGM) improves glycemic control and lifestyle adherence in adults with prediabetes compared to conventional self-monitoring…
- Conditions
- Pre Diabetic, Obesity & Overweight, Insulin Resistance
- Trial name
- PRE-GLIDE (NCT07599072)
- Testing
- CGM Sibionics, On-Call Extra Glucometer
- Where
- 3 sites in Ukraine
- Volunteers
- 80 people
- Sponsor
- Nazarii Kobyliak
Alzheimer Disease, Mild Cognitive Impairment
COMMETS- Combination MCI Metabolic Syndrome
The investigators propose a proof of concept RCT (randomized clinical trial), testing the efficacy of intranasal insulin (INI) with semaglutide, a combination therapy with strong biological plausibility to benefit impaired…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Metabolic Syndrome
- Trial name
- NCT06072963
- Testing
- Semaglutide, Intranasal insulin
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey