Clinical trials: Blockades Neuromuscular
Myofascial Trigger Point Pain
Integrated Neuromuscular Inhibition Technique and Myofascial Release on Cervical Range of Motion and Dysfunction
to findout the improvement by Integrated Neuromuscular Inhibition Technique and Myofascial Release on Cervical Range of Motion and Dysfunction
- Trial name
- NCT05816161
- Testing
- Integrated Neuromuscular Inhibition Technique, Myofascial Release
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Superior University
Residual Neuromuscular Block, Neuromuscular Blockade Monitoring
Comparison of Sugammadex and Sugammadex-neostigmine Combination in the Antagonism of Moderate Neuromuscular Block
In this prospective randomized controlled study the investigators compare the sugammadex-neostigmine combination and single dose sugammadex in terms of side effects and cost for the antagonism of moderate neuromuscular block…
- Trial name
- NCT05228223
- Testing
- Neuromuscular monitoring, reverse of NMB with sugammadex, reverse of NMB with Sugammadex and neostigmin low dose
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Meniscus Tear
Addressing Kinesiophobia in Post-Meniscoplasty Patients Through Progressive Muscle Relaxation Training and Acupressure
The objective of this clinical trial is to determine whether progressive muscle relaxation training and acupressure can reduce kinesiophobia (fear of movement) in patients recovering from meniscoplasty surgery.
- Trial name
- NCT06409715
- Testing
- Enhanced Care with PMRT and Acupressure, standard care
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Gansu University of Chinese Medicine
Skeletal Muscle Relaxation
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS3797 in Healthy Subjects
This is a single-center, open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS3797 in Chinese adults.
- Trial name
- NCT05701826
- Testing
- HRS3797
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Anesthesia
Relationship Between Muscle Mass and Muscle Relaxation Time
Rocuronium block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. There have been several studies reported positive relationship between muscle mass and amount of…
- Trial name
- NCT02617433
- Testing
- Inbody
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Go Eun Bae
Chronic Kidney Disease
Measuring Sleep Quality With Puki in Hemodialysis Patients Performing Progressive Muscle Relaxant Exercises
Chronic kidney disease is a chronic disease that negatively affects the quality of life of individuals, physically, socially and psychologically.
- Trial name
- NCT05604833
- Testing
- Progressive Muscle Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Anxiety
Auricular Stimulation vs. Relaxation for Pre-exam Anxiety
Title of the study: Auricular acupuncture (AA) vs. progressive muscle relaxation for pre-exam anxiety - a randomised crossover study Study period: 04 / 2015 - 07 / 2015 Principal Investigator: PD Dr. T.
- Trial name
- AAvsPMR (NCT03093571)
- Testing
- Auricular stimulation, Relaxation
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Airway Reflexes, Protective, Recovery After Neuromuscular Block
Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block
Protective airway reflexes may be impaired in the postoperative period, creating the potential for aspiration of gastric contents, even after a patient exhibits appropriate response to command.
- Conditions
- Airway Reflexes, Protective, Recovery After Neuromuscular Block, Anesthetic Recovery
- Trial name
- NCT01199237
- Testing
- Sevoflurane, Desflurane, Rocuronium
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- University of California, San Francisco
Morbid Obesity
Surgical Conditions During Laparoscopic Bariatric Surgery
Obesity affects more than 78 million adults in the United States and it is estimated that 35% of the US population is obese. Currently, more than 179,000 bariatric procedures are performed in the US each year with the majority of…
- Trial name
- NCT02703909
- Testing
- Rocuronium, Insufflation pressure
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Missouri-Columbia
Neuromuscular Blockade
Qualitative Analysis of Barriers to Consistent Use of Neuromuscular Monitoring in General Anaesthesia
Monitoring the degree of neuromuscular blockade in general anaesthesia reduces complications and patient discomfort. However, monitoring is not applied consistently by Danish anaesthesia personnel.
- Trial name
- NCT02239965
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Herlev Hospital
Critical Illness
The Use of Sugammadex in the Critically Ill
Moderate and Deep neuromuscular blockade (rocuronium administered to a train of four count 0 and post-tetanic count of 1-2) in critically ill patients needing intubation or procedures can be reversed immediately and effectively…
- Trial name
- NCT03791801
- Testing
- Sugammadex, Neostigmine, Rocuronium
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Addiction
Progressive Muscle Relaxation and Cigarette Craving
Cigarette craving usually occurs with unpleasant feelings, including stress. Progressive Muscle Relaxation (PMR) may reduce level of cigarette craving and/or withdrawal symptoms.
- Trial name
- NCT02153775
- Testing
- Progressive Muscle Relaxation
- Where
- Thailand
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Neuromuscular Blockade, Smoking
Sugammadex and Smoker's Neuromuscular Block
We compared the durations of antagonizing and of the severity of effect of sugammadex used in antagonizing the rocuronium in smoker and non-smoker total 40 patients with using Train of Four(TOF) neuromuscular monitorization.
- Trial name
- NCT05313100
- Testing
- sugammadex
- Volunteers
- 40 people
- Sponsor
- Duzce University
Neuromuscular Blockade
Efficacy and Safety of Sugammadex Dosed According to Actual Body Weight (ABW) or Ideal Body Weight (IBW) in Reversal of Neuromuscular Blockade (NMB) in Morbidly Obese Participants (MK-8616-146)
The purpose of this trial is to evaluate the safety and efficacy of Sugammadex when administered according to actual body weight (ABW) as compared to ideal body weight (IBW) for the reversal of both moderate and deep…
- Trial name
- NCT03346070
- Testing
- Sugammadex 2 mg/kg ABW, Sugammadex 2 mg/kg IBW, Sugammadex 4 mg/kg ABW
- Where
- 24 sites in United States, Austria and 3 more
- Volunteers
- 207 people
- Sponsor
- Merck Sharp & Dohme LLC
Laryngoscopy, Anesthesic Aduction
Comparison Between the Neuromuscular Blockade Onset Monitoring and the Expectation of a Fixed Delay After Curarization on the Quality of Laryngoscopy During Intubation in Elective Surgery (MONITURARE)
During anesthetic induction, the relevance of neuromuscular blockade (NMB) onset monitoring cannot be asserted and its superiority over waiting for a fixed delay (corresponding to pharmacokinetic knowledge of the neuromuscular…
- Conditions
- Laryngoscopy, Anesthesic Aduction, Neuromuscular Blockade, Monitoring
- Trial name
- MONITURARE (NCT03981042)
- Testing
- Monitoring
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Poitiers University Hospital
Affective Disorders, Psychotic Disorder
The Effects of Progressive Muscle Relaxation Therapy in Patients With Schizophrenia
This study applied a randomized parallel case-controlled design. The study purpose was to evaluate the effects of progressive muscle relaxation on anxiety, psychiatric symptoms and quality of life among patients with chronic…
- Trial name
- NCT03667729
- Testing
- progressive muscle relaxation
- Volunteers
- 75 people
- Sponsor
- Taipei Medical University
Arthropathy of Hip
Does Deep Neuromuscular Blockade Improve Operating Conditions During Total Hip Replacements?
During many surgeries, increased muscle tension makes it harder for the surgeon to expose the site of surgery and work within the incision.
- Trial name
- NCT03219294
- Testing
- Vecuronium 0.1 mg/kg, Vecuronium 0.2mg/kg
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Craig Curry
Neuromuscular Blockade, Regional Anesthesia
Bilateral Transversus Abdominis Plane Block Versus Atracurium During Laparoscopic Gynecology Procedures.
A monocentric, prospective, randomized controlled trial, including patients proposed for a laparoscopic gynecologic surgery comparing the muscular relaxing effect of a bilateral ultrasound-guided Transversus Abdominis Plane block…
- Trial name
- NCT03701256
- Testing
- Bilateral ultrasound guided TAP bloc, Neuromuscular blockade agent: Atracurium 01mg/kg per bolus
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- University Tunis El Manar
Maintenance of Deep NM Block Without Overdosing
Fine Tuning of Neuro-muscular Blockade in Robot-assisted Prostatectomy
Assessing the routinely used protokoll for deep NM Block during robot-assisted prostatectomy in general anesthesia. The protocoll contains the repeated dosing of rocuronium according to the results of relaxometry performed with a…
- Trial name
- NMBUro (NCT04638907)
- Testing
- Assessment of NM block
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Peter Biro
Anesthesia Recovery
"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"
Prospective Randomized non inferiority Trial involving adult patients undergoing elective surgery under general anesthesia.56 Patients will be enrolled in 2 groups : full dose sugammadex vs half dose sugammadex for reversal of…
- Trial name
- NCT02375217
- Testing
- Sugammadex, Neostigmine, glycopyrrolate
- Where
- Lebanon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center