Clinical trials: Bladder Neoplasm
Cardiovascular Diseases, Chronic Obstructive Pulmonary Diseases
The Efficacy and Safety of Electronic Cigarettes: a 5-year Follow-up Study
The main aim of this multicentric 5-year follow-up study is to evaluate for the first time the long-term efficacy and safety (in terms of smoking-related serious diseases requiring hospitalization) of e-cigarette smoking…
- Conditions
- Cardiovascular Diseases, Chronic Obstructive Pulmonary Diseases, Cancer of the Lung, Cancer of the Bladder
- Trial name
- NCT01785537
- Where
- Italy
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Bladder Cancer, Biomarkers
Urinary Biomarkers in the Detection of Urothelial Carcinoma of the Bladder
To assess the persistence of bladder cancer-specific biomarkers in urine collected pre-operatively, in resected cancer tissue, and in urine collected post-operatively.
- Trial name
- NCT02745301
- Testing
- Collection of urine and bladder tumor specimens
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Superficial Bladder Cancer
Sequential Whole Bladder Photodynamic Therapy (WBPDT) in the Management of Superficial Bladder Cancer
This protocol is evaluating efficacy and toxicity of three sequential whole bladder photodynamic treatment with Photofrin and red laser light (630 nm) in the management of superficial bladder cancer (non-muscle invasive) in those…
- Trial name
- NCT00322699
- Testing
- Whole bladder laser light treatment as an alternative to radical cystectomy, Photofrin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- North Florida/South Georgia Veterans Health System
Urinary Bladder Neoplasms
Narrow-band Imaging Diagnostic Classification System for Bladder Tumors
The goal of this observational study is to learn about the morphological characteristics of different bladder lesions under narrow-band imaging（NBI） techniques in All patients requiring cystoscopy and biopsy.
- Trial name
- NBI (NCT05611762)
- Where
- China
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University (Qingdao)
HER2-positive Breast Cancer, HER2 Low
ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer
This is an open-label, single-arm, multi-site phase I/Ib trial with SYD985, an antibody-drug conjugate (ADC) targeting HER2 on the cell membrane, combined with paclitaxel.
- Conditions
- HER2-positive Breast Cancer, HER2 Low, SYD-985, SYD985
- Trial name
- NCT04602117
- Testing
- Vic-trastuzumab duocarmazine (SYD985) + paclitaxel
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- QuantumLeap Healthcare Collaborative
Prostate Cancer, Bladder Cancer
Duke Urology Database and Specimen Bank
The proposed project is aimed to build a Duke University-specific longitudinal urologic surgery database. It will be used as the main resource to support future research within Urology and Duke University.
- Conditions
- Prostate Cancer, Bladder Cancer, Erectile Dysfunction, Incontinence
- Trial name
- NCT00978991
- Where
- United States
- Volunteers
- 87,820 people, healthy volunteers welcome
- Sponsor
- Duke University
Lung Cancer (NSCLC)
Snakehead Fish Extract and Curcumin Co-Supplementation in Advanced Lung Cancer on Inflammation, Nutritional Status, and Quality of Life
Background: Patients with advanced lung cancer receiving systemic therapy often experience nutritional decline, systemic inflammation, and impaired quality of life.
- Trial name
- BMI (NCT07906626)
- Testing
- Snakehead Fish Extract and Curcumin
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara
Hematuria, Urination Disorders
Rigid Versus Flexible Cystoscopy in Women
The study will help define the best tolerated approach to cystoscopy in women by randomly comparing flexible to rigid cystoscopy.
- Conditions
- Hematuria, Urination Disorders, Voiding Dysfunction, Recurrent Urinary Tract Infection
- Trial name
- NCT00214045
- Testing
- Flexible Cystoscopy, Rigid Cystoscopy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Urothelial Carcinoma, Bladder Cancer
Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for the Detection of Urothelial Carcinoma
Clinical trial to evaluate the performance characteristics(sensitivity and specificity) of AnchorDx's urine DNA methylation/somatic mutation profiling assay for detecting urothelial carcinoma compared to pathology in patients.
- Trial name
- NCT04314245
- Testing
- Active Comparator: Pathology, Active Comparator: Clinical Diagnosis, Genetic test: AnchorDx's urine DNA methylation/somatic mutation profiling assay
- Where
- China
- Volunteers
- 1,170 people, healthy volunteers welcome
- Sponsor
- AnchorDx Medical Co., Ltd.
Bladder Cancer
Paclitaxel-binding Albumin and Cisplatin as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer
This is a phase II study of Paclitaxel-binding albumin, Cisplatin as neoadjuvant chemotherapy in patients with muscle-invasive urothelial carcinoma of the bladder.
- Trial name
- NCT04060459
- Testing
- Paclitaxel-binding albumin
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Third Military Medical University
Prostate Cancer (Adenocarcinoma), Bladder Cancer
Enhancing Readability of Lay Abstracts and Summaries for Medical Knowledge Using Generative Artificial Intelligence (BRIDGE AI 3)
This trial tests if AI can help make medical info clear and readable. Many patients struggle to find medical informations that easy to read and understand from verified medical sources.
- Conditions
- Prostate Cancer (Adenocarcinoma), Bladder Cancer, Kidney Cancers, Testis Cancer
- Trial name
- NCT07568444
- Testing
- Pub2Post
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Addiction, Alcohol, Urinary Tract Disease
Does Homebrewing Beer Affect Urinary Tract Symptoms and Bladder Cancer
In this study, investigators aim to reveal the harmful effects of increasing consumption of homemade beer in recent years on the urinary tract.
- Trial name
- NCT05134675
- Testing
- Homemade beer
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Muscle-Invasive Bladder Carcinoma, Bladder Cancer Stage II
Addressing Barriers to Palliative Care Use in Bladder Cancer
Investigators plan to establish an in-depth understanding of knowledge and beliefs about palliative care in advanced Bladder Cancer patients and their caregivers, and to identify factors associated with positive and negative…
- Conditions
- Muscle-Invasive Bladder Carcinoma, Bladder Cancer Stage II, Bladder Cancer Stage III, Bladder Cancer Stage IV
- Trial name
- NCT04598724
- Testing
- Surveys
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Prostate Cancer, Kidney Cancer
Mind-Body Health in Uro-Oncology: Research Study
In this study, the researchers will examine the effects of post-mindfulness intervention email and text messages to promote maintenance of intervention effects over time in a uro-oncology sample (clinically localized prostate…
- Conditions
- Prostate Cancer, Kidney Cancer, Bladder Cancer
- Trial name
- NCT03852030
- Testing
- Text or email message
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Urinary Bladder Cancer
Role of Hypofractionated Radiotherapy With Concurrent Gemcitabine in Treatment of Urinary Bladder Carcinoma
Estimate the response to modified hypofractionated radiotherapy concurrent with Gemcitabine in urinary bladder cancer patients . Estimate local control, relapse free survival, overall survival and bladder preservation rate.
- Trial name
- NCT04812145
- Testing
- Chemoradiation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bladder Cancer, Urocystitis
A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose bladder cancer by comparing with clinical standard method…
- Conditions
- Bladder Cancer, Urocystitis, Urinary Bladder Stone, Urothelial Carcinoma
- Trial name
- NCT05337189
- Testing
- Urine DNA methylation analysis, medical imaging and/or cystoscopy and/or pathological examination
- Where
- China
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Bladder Cancer
Antiangiogenic Effects of BCG on Urinary Concentration of Angiogenic Factors
To determine if there is an association between basic fibroblast growth factor,vascular endothelial growth factor, and interleukin levels and a patients response to BCG treatment ( as standard treatment)in the urine of patients…
- Trial name
- NCT00216814
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Gall Bladder Carcinoma
Incidental Gallbladder Carcinoma :Incidence and Clinical Significance in Specimens From Routine Cholecystectomies in Sohag Locality
Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality
- Trial name
- NCT07885800
- Testing
- histopathology of gall bladder
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Diet, Healthy, Urinary Bladder Diseases
The COOKER-BLADDER Trial
The goal of this interventional study is to test the influence of food intake with characteristics of the urinary bladder. The main questions it aims to answer are: How does food intake modify the characteristics of urothelial…
- Conditions
- Diet, Healthy, Urinary Bladder Diseases, Oncogenesis
- Trial name
- NCT05643963
- Testing
- Dietary regimens
- Where
- 2 sites in Switzerland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Roland Seiler-Blarer
Bladder Cancer
Expression of MCM5 in Urine in Patients With Urothelial Cancers
In patients with non-muscle-invasive bladder cancer, the development and introduction to the clinical practice of an adequately accurate biomarker may allow to limit the indications for performing control cystoscopy.
- Trial name
- NCT03796299
- Testing
- Assessment of expression of MCM5 in the urine (ADX Bladder)
- Where
- Poland
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw