Clinical trials: Bipolar Disorder NOS
Mood Disorders, Bipolar Disorder
Mood Patient Powered Research Network (MoodNetwork)
The MoodNetwork, a patient-powered research network (PPRN), is one of 18 PPRNs participating in Patient-Centered Outcomes Research Institute's (PCORI) PCORnet network.
- Conditions
- Mood Disorders, Bipolar Disorder, Major Depressive Disorder, Depression
- Trial name
- NCT02453438
- Testing
- Patient Reported Outcomes
- Where
- United States
- Volunteers
- 5,716 people
- Sponsor
- Massachusetts General Hospital
Bipolar Disorder
Reproductive Function in Women With Bipolar Disorder
Many studies have shown that patients with bipolar disorder are prone to reproductive dysfunction, including polycystic ovary syndrome, hyperprolactinemia, and amenorrhea.
- Trial name
- NCT05307848
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Bipolar Disorder
Psychoeducation for Patients With Bipolar Disorder in Rwanda
Background: Mental health- and neurological disorders constitute 13% of the global burden of disease. Alarmingly this burden has risen by 41% in the last 20 years.
- Trial name
- NCT04671225
- Testing
- Groups Psychoeducation, Waiting-list
- Where
- 2 sites in Rwanda
- Volunteers
- 154 people
- Sponsor
- University of Aarhus
Bipolar Disorder
Observation of Clozapine Treatment Safety in Bipolar Disorder.
The purpose of the registry is to record incidence of adverse events during treatment with clozapine in patients suffering from bipolar disorder.
- Trial name
- CloGD (NCT06011460)
- Testing
- Clozapine
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Gdansk
Bipolar Disorder
Aripiprazole in the Treatment of Bipolar Depression
A systematic open-label prospective pilot study to assess aripirazole for acute bipolar depression, with a secondary assessment of longer-term mood stabilization.
- Trial name
- NCT00226317
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Depression, Bipolar Disorder
Insulin Resistance in Patients With Major Depression
The purpose of this study is to study the relationship between insulin and glucose action and neuropsychological functioning (memory, attention, general thinking abilities) in persons with depression.
- Conditions
- Depression, Bipolar Disorder, Mood Disorders, Insulin Resistance
- Trial name
- NCT01106313
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Stanford University
Bipolar Disorder, Major Depressive Disorder
The Gut Microbiota of Bipolar and Depression
Background: The gut microbiome is emerging as an important factor in regulating mental health yet it remains unclear what the target should be for psychiatric treatment.
- Trial name
- NCT03062332
- Testing
- Faecal genome
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Mental Illness Persistent, Cardiovascular Prevention
Cardiac Rehabilitation for Cardiovascular Risk Reduction in People With Severe and Persistent Mental Illness
The goal of this prospective, randomized trial is to explore the link between cardiovascular disease and mortality in individuals with severe and persistent mental illness (SPMI).
- Trial name
- NCT05659498
- Testing
- Cardiac Rehabilitation Program
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Borderline Personality Disorder, BPD
Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations
Social cognition impairment is critical to the pathology and morbidity of a number of psychiatric disorders, including the schizophrenia spectrum, the autism spectrum and the personality disorders, thus representing a dimension…
- Conditions
- Borderline Personality Disorder, BPD, Schizotypal Personality Disorder, SPD
- Trial name
- NCT02149823
- Testing
- Syntocinon 24 Intranasal Units (IU), Syntocinon 40 Intranasal Units (IU)
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Maria de las Mercedes Perez Rodriguez
Bipolar Disorder
Algorithm Guided Treatment Strategies for Bipolar Depression
The purpose of the AGTs-BD study is to compare the treatment outcome and safety profiles between different mood stabilizers combination treatments in the patients with bipolar disorders, currently suffered from depression episode.
- Trial name
- AGTs-BD (NCT01938859)
- Testing
- Lithium, Quetiapine, Shuganjieyu capsule
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Shanghai Mental Health Center
Bipolar Disorder
Occupational Stress and Bipolar Disorder
Bipolar disorder is a mental disorder characterized by alternance of depressive and manic phases, separated by intercritical phases (euthymia). The majority of patients report occupation and professional difficulties.
- Trial name
- NCT03162380
- Testing
- Date collection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Bipolar Disorder
Aripiprazole in Late Life Bipolar Disorder
The purpose of this research study is to analyze the effectiveness and tolerability of a new medication, aripiprazole (Abilify), in individuals age 50 years and older who have bipolar disorder (manic-depressive illness).
- Trial name
- NCT00194038
- Testing
- Aripiprazole
- Volunteers
- 20 people
- Sponsor
- University Hospitals Cleveland Medical Center
Bipolar Disorder
Naturalistic Study, Comparison of Divalproex Extended Release (ER) and Quetiapine for Adults With Acute Mania or Mixed Episodes
The primary objective of this study is to compare the efficacy and tolerability of quetiapine versus divalproex extended-release administered in a rapid oral loading fashion in the treatment of acute episodes of mania or mixed…
- Trial name
- NCT00397020
- Testing
- divalproex ER, quetiapine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Bipolar Disorder
Seroquel in Acute Mania: Study to Investigate if Valproate Add-On Therapy is Superior to Quetiapine Monotherapy in Acutely Manic Patients
The primary purpose is to investigate whether the addition of sodium valproate will be superior to treatment with quetiapine (Seroquel) given as monotherapy for an additional 14 days in non-responding patients after a 14 day…
- Trial name
- NCT00139074
- Testing
- Quetiapine fumarate, sodium valproate
- Where
- 7 sites in Denmark
- Volunteers
- 17 people
- Sponsor
- AstraZeneca
Bipolar Disorder, Suicidal Ideation
Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China
This study aims to use a retrospective cohort approach to explore the impact of lithium carbonate on suicide and self-harm related events among adolescents and young adults with bipolar disorder in China.The primary objective of…
- Conditions
- Bipolar Disorder, Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self Injury
- Trial name
- NCT06424613
- Testing
- Lithium Carbonate, Non-lithium medication
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University
Bipolar Disorder
Safety And Efficacy Of Ziprasidone In Children And Adolescents With Bipolar I Disorder (Manic Or Mixed) (Protocol A1281196)
The purpose of this study is to determine if flexibly-dosed ziprasidone is safe and effective for the treatment of children and adolescents (ages 10-17) with Bipolar l Disorder (Manic or Mixed).
- Trial name
- NCT01117220
- Testing
- Ziprasidone Oral Capsules
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Bipolar Disorder
Psychosocial Therapy Plus Maintenance Pharmacotherapy for Treating Bipolar Disorder
This study will evaluate the effectiveness of interpersonal and social rhythm therapy (IPSRT) versus clinical status and symptom response therapy (CSSRT) in reinforcing the treatment of bipolar disorder in individuals who are…
- Trial name
- NCT00227968
- Testing
- Interpersonal Social Rhythm Therapy (IPSRT), Clinical Status and Symptom Response Therapy (CSSRT)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of Pittsburgh
Bipolar Disorder
Efficacy and Safety of Quetiapine Compared With Valproate in the Treatment of Patients With Bipolar Disorder and Rapid Cycling
The purpose of the study is to evaluate the efficacy of quetiapine compared to valproate during a 12 month treatment period in subjects with Bipolar Disorder I or II with Rapid Cycling.
- Trial name
- NCT00254774
- Testing
- quetiapine fumarate or valproate
- Where
- 3 sites in Germany
- Volunteers
- 44 people
- Sponsor
- AstraZeneca
Treatment Resistant Depression, Major Depressive Episode
University of Iowa Interventional Psychiatry Service Patient Registry
The purpose of this study is to examine the effects of interventional/procedural therapies for treatment-resistant depression (TRD) and Obsessive-Compulsive Disorder (OCD).
- Conditions
- Treatment Resistant Depression, Major Depressive Episode, Major Depression, Major Depressive Disorder
- Trial name
- NCT04480918
- Testing
- Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Ketamine
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Mark Niciu
Bipolar Depression
Quetiapine Efficacy in Bipolar Depression Study
To reassure the clinical study data on Seroquel antidepressant efficacy in patients who are diagnosed as bipolar depression
- Trial name
- QUEEN (NCT00523601)
- Where
- 3 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- AstraZeneca