Clinical trials: Bipolar Disorder II
Bipolar Disorders
A NIS Evaluating the Treatment Patterns of Atypical Antipsychotics in Patients Diagnosed With Bipolar I or II Disorder
The purpose of this NIS is to obtain data on how AAPs are used in DSM-IV-TR Bipolar I and II Disorder, in the course of a major depressive episode.
- Trial name
- HARMONY (NCT00888264)
- Where
- 45 sites in Belgium
- Volunteers
- 152 people
- Sponsor
- AstraZeneca
Depression, Bipolar
A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar Depression
This is an 8-week, multicenter, randomized, double blind, placebo controlled study to evaluate the efficacy and safety of aripiprazole as an adjunctive treatment with mood stabilizer for the treatment of patients (outpatients or…
- Trial name
- APOLLO (NCT03423680)
- Testing
- Abilify 2, 5, 10, 15mg (Tablet)
- Where
- South Korea
- Volunteers
- 390 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Bipolar II Disorder
add-on Low Dose Memantine in Middle-to-old Aged Bipolar II Disorder Patients
The investigators hypothesized that add-on memantine (MM) 5 mg/day may reduce chronic inflammation, and subsequently improve neuro-progression process and cognitive function in middle-to-old aged bipolar II disorder (BP-II)…
- Trial name
- NCT04035798
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Cheng-Kung University Hospital
Bipolar Disorder II
Efficacy and Mechanism of IPSRT for Bipolar II Disorder
This project is based on the biphasic instability model and social timing theory, utilizing IPSRT to help regulate social interactions and establish regular daily habits, alleviate emotional symptoms, and prevent.
- Trial name
- NCT07654348
- Testing
- Quetiapine (drug), Psychopharmacological treatment
- Where
- China
- Volunteers
- 216 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Bipolar Affective Disorder, Currently in Remission, Bipolar Disorder I
Effect of Behavioral Intervention on Cannabinoid Receptors in BAD
The objective of this study is to determine whether the practice of a non-drug related intervention technique (behavioral modification technique consisting of a combination of breathing exercises, cold exposure and meditation)…
- Conditions
- Bipolar Affective Disorder, Currently in Remission, Bipolar Disorder I, Bipolar Disorder II
- Trial name
- WHM_BAD (NCT04168697)
- Testing
- Wim Hof method
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Schizophrenia, Schizophreniform Disorder
Integrated Care in Psychotic Disorders With Severe Mental Illness
The study examine the effectiveness of an integrated care program including therapeutic assertive community treatment (ACT) for people with psychotic disorders fulfilling severe and persistent mental illness (SPMI, ACCESS-II…
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, Delusional Disorder
- Trial name
- ACCESS-II (NCT01888627)
- Testing
- Integrated care
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Bipolar II Disorder
Differential Responses to Drugs and Sweet Tastes
Young adults who exhibit "bipolar phenotype" (BPP), defined as occasional episodes of mood elevation and heightened activity, are at risk for several psychiatric disorders, including problem use of drugs and alcohol.
- Trial name
- HAP (NCT03810703)
- Testing
- d-amphetamine 10 mg oral capsule, d-amphetamine 20 mg oral capsule
- Where
- 2 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Bipolar Disorder
Mindfulness-Based Cognitive Behavior Therapy for Bipolar Disorder
The purpose of the study is to investigate the efficacy of mindfulness-based cognitive-behavior therapy (MBCT) for improvement of symptoms associated with bipolar disorder, by comparing MBCT to supportive psychotherapy.
- Trial name
- MBCT (NCT01126827)
- Testing
- Mindfulness-Based Cognitive Behavioral Therapy or Supportive Psychotherapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder, Bipolar Disorder II
Long-term Potentiation Disruption Underlying Cognitive Impairment in ECT
Cognitive problems, like memory loss, are common after brain injuries like trauma or stroke. These problems make daily life harder, and the investigators don't yet know the best ways to help the brain recover.
- Trial name
- LTP-DUCIECT (NCT06733558)
- Testing
- Electroconvulsive Therapy
- Where
- United States
- Sponsor
- University of New Mexico
Bipolar Disorder I or II
Tranylcypromine Treatment of Bipolar Depression
This study seeks to investigate whether tranylcypromine (Parnate®) might be an effective treatment of bipolar depression. New treatments are needed, as there is little evidence that standard antidepressants are effective in…
- Trial name
- NCT01430455
- Testing
- Tranylcypromine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- New York State Psychiatric Institute
Bipolar II Disorder
Seroquel in the Treatment of Dysphoric Hypomania in Bipolar II
1. The primary objective of this study is to examine the efficacy of quetiapine (Seroquel) in treatment of dysphoric hypomania in patients with Bipolar II disorder. 2.
- Trial name
- NCT00186043
- Testing
- Quetiapine/Seroquel
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Stanford University
Attention Deficit/Hyperactivity Disorder, Bipolar Disorder
To Evaluate the Safety and Metabolic Profile of Vyvanse for the Treatment of ADHD in Euthymic Adults With Bipolar I/II Disorder
ADHD in the adult population is associated with several measures of harmful dysfunction. For example, adult ADHD is associated with high rates of separation/divorce and never-married status, lower educational attainment and…
- Trial name
- NCT01263548
- Testing
- lisdexamfetamine dimesylate
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University Health Network, Toronto
Bipolar Disorder I, Bipolar Disorder II
A Study to Evaluate SAGE-217 in Participants With Bipolar I/II Disorder With a Current Major Depressive Episode
This is an open-label study evaluating the safety, tolerability, pharmacokinetics, and efficacy of SAGE-217 in the treatment of participants with bipolar I/II disorder with a current major depressive episode.
- Conditions
- Bipolar Disorder I, Bipolar Disorder II, Major Depressive Episode
- Trial name
- NCT03692910
- Testing
- SAGE-217
- Where
- 11 sites in United States
- Volunteers
- 35 people
- Sponsor
- Biogen
Bipolar Depression, Bipolar I Disorder
SYNCED - SYNChronized Eating in Bipolar Depression Study
Bipolar disorders (BD) are a group of complex disorders that impact mood, behaviour and cognition and are known to cause significant suffering and impairment.
- Conditions
- Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
- Trial name
- NCT06560957
- Testing
- Time restricted eating, Eating ad libitum with nutritional counselling
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Ottawa
Major Depressive Disorder, Bipolar I Disorder
Digital Phenotypes for Predicting Depression_Validation
This 12-month, single-site prospective observational study will prospectively monitor the recurrence of mood episodes while continuously collecting passive digital phenotypes in individuals with and without mood disorders.
- Conditions
- Major Depressive Disorder, Bipolar I Disorder, Bipolar II Disorder, Mood Disorders
- Trial name
- NCT07880015
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Bipolar Disorder, Depression
Antidepressant Therapy in Treating Bipolar Type II Major Depression
This study will compare the safety and effectiveness of antidepressant therapy versus mood stabilizing therapy in treating people with bipolar type II major depression.
- Trial name
- NCT00602537
- Testing
- Venlafaxine, Lithium Carbonate
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Pennsylvania
Bipolar I or II Disorder
Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder
Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population in the United States. The purpose of this study is to assess how safe and effective ABBV-932 is in treating participants with…
- Trial name
- NCT07220460
- Testing
- ABBV-932
- Where
- 49 sites in United States, Puerto Rico
- Volunteers
- 84 people
- Sponsor
- AbbVie
Bipolar Type II Disorder, Depression, Bipolar
Light-Therapy in the Treatment of the Acute Phase of the Bipolar Type II Depression
The purpose of this study is to evaluate the efficacy and safety of light therapy for the treatment of bipolar type II patients relapsing into a depressive phase during autumn or winter.
- Trial name
- BPII-DEP-LT (NCT00590265)
- Testing
- Northern Light Technology (SADelite lamp) bright light-therapy, Northern Light Technology (SADelite lamp) Dim light-therapy
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Douglas Mental Health University Institute
Bipolar II Disorder
Psilocybin Therapy for Depression in Bipolar II Disorder
The purpose of this study is to determine the safety, tolerability, and feasibility of psilocybin therapy in people with Bipolar II Disorder.
- Trial name
- BAP (NCT05065294)
- Testing
- Psilocybin therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Francisco
Schizophreniform Disorder, Bipolar I Disorder
Prevention of Weight Gain in Early Psychoses
The purpose of this study is to determine whether individuals with psychotic spectrum disorders ( Schizophrenia, Schizoaffective disorder,Schizophreniform Disorder, Bipolar Disorder (Type I),Bipolar Disorder (Type II),Major…
- Conditions
- Schizophreniform Disorder, Bipolar I Disorder, Bipolar II Disorder, Major Depressive Disorder
- Trial name
- NCT01075295
- Testing
- Behavioural Intervention for the Prevention of Weight Gain, TAU
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Centre for Addiction and Mental Health