Clinical trials: Bipolar Disorder Depression
Depression, Alcoholism
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
The purpose of this study is to learn the environmental and psychological factors that impact suicidality in patients diagnosed with Bipolar Disorder.
- Conditions
- Depression, Alcoholism, Drug Abuse
- Trial name
- NCT02604277
- Testing
- Interpersonal and Social Rhythm Therapy (ISRT), Bipolar-Specific Cognitive Behavioral Therapy (CBT), Mindfulness-Based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Resistant Depression, Treatment, Bipolar Depression
Efficacy and Biomarkers of Response of TBS in Treatment Resistant Depression
Theta Burst Transcranial Magnetic Stimulation (TBS) in dorsolateral prefrontal cortex (DLPFC) has shown efficacy and safety as an adjuvant strategy for resistant to treatment depression (RTD) in daily sessions during 4-6 weeks…
- Trial name
- EMTtfNI (NCT04998773)
- Testing
- Theta Burst Transcranial Magnetic Bilateral Stimulation, Theta Burst Transcranial Magnetic Unilateral Stimulation
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Schizophrenia, Schizoaffective Disorder
Abilify Therapy for Reducing Comorbid Substance Abuse
It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: Reduction in the amount of alcohol and/or drugs used as measured by the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT00208169
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Psychosis, Major Depression
Peer Support for Severe Mental Disorders
The purpose of this study is to determine wether peer support is effective for the treatment of people with severe mental illness.
- Conditions
- Psychosis, Major Depression, Bipolar Disorder, Borderline Personality Disorder
- Trial name
- PEER (NCT02276469)
- Testing
- peer support
- Volunteers
- 200 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Depression, Schizophrenia
Comparison of Propofol Target-Controlled Infusion Anesthesia and Bolus Injection in Electroconvulsive Therapy
Electroconvulsive therapy (ECT) serves as an effective adjuvant or alternative modality for major depressive disorder, schizophrenia, or bipolar affective disorder refractory to or contraindicated to psychopharmacological…
- Conditions
- Depression, Schizophrenia, Bipolar Disorder, Cognitive Dysfunction
- Trial name
- NCT03863925
- Testing
- Target controlled infusion, Schnider model, Bolus injection of Propofol
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Bipolar Disorder
The Study of Effectiveness Repetitive Transcranial Magnetic Stimulation in Bipolar Depression
The aim of this study is to investigate the effect of repetitive TMS in reduction of depressive symptoms in patients with bipolar disorder.
- Trial name
- NCT01932749
- Testing
- Transcranial Magnetic stimulation
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- University of Tehran
Depression, Bipolar, Depression, Unipolar
Pramipexole to Target "Anhedonic Depression"
The heterogeneity of depression suggests that different neurocircuits and pathophysiological mechanisms are involved. Anhedonia - the inability to experience pleasure from, or the lack of motivation to carry out, usually…
- Conditions
- Depression, Bipolar, Depression, Unipolar, Dysthymia, Anhedonia
- Trial name
- PILOT-PRAXOL (NCT04121091)
- Testing
- Pramipexole Pill
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Region Skane
Bipolar Disorder (BD), Bipolar Disorder Depression
Time Restricted Eating (TRE) in Bipolar Disorder
This is a randomized controlled trial investigating the effects of an 8-TRE intervention compared to a wait list (control) on metabolic health and body composition in people diagnosed with BD and who are currently obese and at…
- Conditions
- Bipolar Disorder (BD), Bipolar Disorder Depression, Overweight (BMI > 30)
- Trial name
- TREBD (NCT07211217)
- Testing
- Time Restricted Eating
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Bipolar Disorder, Depression
Effect of Immersive Virtual Reality-based Cognitive Remediation in Patients With Mood - or Psychosis Spectrum Disorders
The goal of this clinical trial is to investigate the effect of a four-weeks, intensive virtual reality (VR)-based cognitive remediation (training) programme involving simulated daily-life challenges on cognition and functional…
- Conditions
- Bipolar Disorder, Depression, Psychotic Disorders, Cognitive Impairment
- Trial name
- NCT06038955
- Testing
- Virtual reality Based Cognitive Remediation, Virtual reality control training
- Where
- Denmark
- Volunteers
- 62 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Anxiety Disorders and Symptoms, Depression
Personalized Mobile Cognitive Behavioral Therapy Application
This study aims to compare the effectiveness of a standard mobile cognitive behavioral therapy program to a personalized mobile cognitive behavioral therapy program that introduces new skills over a shorter period of time.
- Conditions
- Anxiety Disorders and Symptoms, Depression, Bipolar Disorder, Symptoms
- Trial name
- NCT05699525
- Testing
- Personalized MAYA Mobile App, General MAYA Mobile App
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Weill Medical College of Cornell University
Postpartum Depression
Quetiapine in the Treatment of Postpartum Depression (PPD) in Bipolar Disorder (BD), Type II
This is a 9-week single-centre, open-label, dose-escalating study evaluating the efficacy and safety of Quetiapine XR given as monotherapy in the treatment of non-lactating, post-partum women diagnosed with Bipolar II Disorder.
- Trial name
- NCT01527448
- Testing
- Quetiapine XR (seroquel)
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- BC Women's Hospital & Health Centre
Bipolar Affective Disorder
Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II.
Initially, observational studies suggested a possible effect of Lacosamide on depressive and anxious symptoms in individuals with epilepsy, and later, an open-label study demonstrated the efficacy of lacosamide in improving…
- Trial name
- NCT07412132
- Testing
- Lacosamide
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Bipolar Disorder, Bipolar Depression
Braining- Aerobic Physical Activity as Add on Treatment in Bipolar Depression
Hypothesis: the hypothesis of the study is that aerobic physical exercise (PE) performed with the method Braining accelerates recovery from bipolar depression as well as improves psychiatric and somatic health in individuals with…
- Conditions
- Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder
- Trial name
- NCT05340686
- Testing
- Aerobic Physical Exercise, Relaxing Physical Exercise, Information about physical exercise
- Where
- Sweden
- Volunteers
- 54 people
- Sponsor
- Region Stockholm
Chronic Mental Illness, Major Depression
My Coach Connect: An Automated Telephone-based Reporting System for Patients With Mental Illness
This is a pilot study for a novel, automated telephone system called "My Coach Connect". The purpose of the study is to evaluate the feasibility and effectiveness of this telephone tool while engaging clients and providers in…
- Conditions
- Chronic Mental Illness, Major Depression, Schizophrenia, Bipolar Disorder
- Trial name
- MCC (NCT01749124)
- Testing
- My Coach Connect
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- RAND
Recent-Onset Psychosis, Schizophrenia
Multifamily Psychoeducation and Cognitive Remediation for Recent-Onset Psychosis
The goal of this study is to determine whether pairing multifamily group psychoeducation with cognitive remediation may facilitate improved outcomes among individuals with recent-onset psychosis.
- Conditions
- Recent-Onset Psychosis, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder With Psychotic Features
- Trial name
- NCT01196286
- Testing
- Multifamily Group Psychoeducation (MFG), Cognitive Remediation (CR)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arizona
Bipolar Disorder Type II, Mood Depressive Disorder
Exploration of Differences in Metabolite Concentrations by NMR Spectroscopy in the Ventral Striatum, Anterior Cingulate Cortex and Prefrontal Cortex in Euthymic Patients With Unipolar and Bipolar Type II Mood Disorders, as Well as in Healthy Subjects
The presented project is an open and controlled single-center prospective exploratory study, evaluating the metabolic concentrations in the ventral striatum (VS), the Anterior cingulate cortex (ACC) and the prefrontal cortex…
- Trial name
- RMN-UNIBI (NCT05650788)
- Testing
- NMR spectrometry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Schizophrenia, Bipolar 1 Disorder
A Trial to Measure the Difference in All-cause Hospitalizations for Participants Who Are Using Abilify MyCite Versus Virtual Matched Controls in Adults With Schizophrenia, Bipolar 1 Disorder, and Major Depressive Disorder
The primary objective of this pragmatic clinical trial (Main Study) was to assess the difference between all-cause hospitalizations in participants using Abilify MyCite versus virtual matched controls.
- Conditions
- Schizophrenia, Bipolar 1 Disorder, Major Depressive Disorder
- Trial name
- NCT03643159
- Testing
- Abilify MyCite - Digital Medicine System, Aripiprazole or other oral antipsychotics
- Where
- 5 sites in United States
- Volunteers
- 2 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Bipolar Disorder
FMRI Study of Brain Response Before and After Lithium Treatment in People With Bipolar Disorder
This study will assess the effects of bipolar disorder on brain activity and will determine if medication changes the brain activity in people with bipolar disorder.
- Trial name
- NCT00596622
- Testing
- Lithium
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Indiana University
Schizophrenia, Depression
Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses
This study will determine the effectiveness of a peer support system in increasing physical activity and effecting health behavior change in people with serious mental illnesses.
- Conditions
- Schizophrenia, Depression, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT00458094
- Testing
- Physical activity intervention with peer support (PA+PS), Physical activity intervention without peer support (PA)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Depressive Disorder, Major, Bipolar Disorder
In-person vs. Remote Wellness Support
The study team will use components of the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) framework to compare Cognitive Adaptation Training (CAT) to Remotely delivered Cognitive Adaptation Training (R-CAT)…
- Conditions
- Depressive Disorder, Major, Bipolar Disorder, Schizo Affective Disorder, Schizophrenia
- Trial name
- R-CAT (NCT04526067)
- Testing
- CAT, R-CAT
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- The University of Texas Health Science Center at San Antonio