Clinical trials: Bipolar
Bipolar Disorder, Depression
Disseminating Evidence-based Mood Disorder Chronic Care Models
This study will determine if a version of the chronic care model for individuals with mood disorders can improve patient health.
- Trial name
- NCT01615458
- Testing
- Chronic Care Model for Mood Disorders
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Severe Mental Illness, Depression / Major Depressive Disorder
Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN)
This randomized, rater-blind, multicenter clinical trial will evaluate whether a personalized pharmaco-lifestyle intervention improves mental functioning in adults with severe mental illness, including schizophrenia, bipolar…
- Conditions
- Severe Mental Illness, Depression / Major Depressive Disorder, Bipolar Disorder (BD), Schizophrenia
- Trial name
- LIFETRAIN (NCT07586150)
- Testing
- Semaglutide (SEMA), Exercise module, Anti-inflammatory diet module
- Where
- 5 sites in Austria, Germany and 1 more
- Volunteers
- 140 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Bipolar Disorder
Trial of Olanzapine in Patients With Manic or Mixed Episode of Bipolar I Disorder
The purpose of this study is to confirm the efficacy of olanzapine in the treatment of manic or mixed symptoms associated with bipolar I disorder.
- Trial name
- NCT00129220
- Testing
- olanzapine, haloperidol
- Where
- 16 sites in Japan
- Volunteers
- 224 people
- Sponsor
- Eli Lilly and Company
Anxiety Disorder, Mood Disorder
New Drugs in the Treatment of Mood Disorders
This clinical study compares the effectiveness of two anticonvulsants Lamotrigine (Lamictal) Monotherapy and Gabapentin (Neurontin) in patients with treatment resistant affective disorders.
- Conditions
- Anxiety Disorder, Mood Disorder, Psychotic Disorder
- Trial name
- NCT00001482
- Testing
- Lamotrigine (Lamictal® (Registered Trademark), Gabapentin (Neurontin® (Registered Trademark))
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Femoral Neck Fractures
Project JAY HAP Registration Study
This is a prospective, randomized, multicenter clinical study in elderly Chinese subjects to compare the safety and efficacy of the SS Bipolar Head and SL-TWIN Stem with Bipolar Head and SL-PLUS Stem in hemiarthroplasty of the hip
- Trial name
- NCT02347397
- Testing
- SS Bipolar Head + SL-TWIN Stem, Bipolar Head + SL-PLUS Stem
- Where
- 5 sites in China
- Volunteers
- 134 people
- Sponsor
- Smith & Nephew Orthopaedics (Beijing) Limited
Bipolar Disorder
Olanzapine Versus Lithium in the Treatment of Acute Depression in Patients With Bipolar II or Bipolar Not Otherwise Specified(OL Study)
Determine the efficacy and tolerability of olanzapine for treatment of acute depression in patients with bipolar II or bipolar disorder NOS compared with lithium.
- Trial name
- NCT02287259
- Testing
- olanzapine, lithium
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Tadashi Hasegawa
Bipolar Affective Disorder
rTMS in the Treatment of Bipolar Depression
Bipolar affective disorder (BPAD) is: A serious mental illness Estimated to be present in as high as 6.4% of the population in Western populations Associated with considerable disability and high morbidity.
- Trial name
- NCT00436020
- Testing
- TMS
- Where
- Australia
- Volunteers
- 51 people
- Sponsor
- Bayside Health
Depression, Bipolar
Olanzapine Treatment of Patients With Bipolar I Disorder
The purpose of this study is to assess whether olanzapine is superior to placebo in patients with bipolar depression.
- Trial name
- NCT00510146
- Testing
- Olanzapine
- Where
- 16 sites in China, Japan and 1 more
- Volunteers
- 514 people
- Sponsor
- Eli Lilly and Company
Schizophrenia, Schizoaffective
Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness
This is a hybrid1, effectiveness-implementation study of yoga-based exercises (YE) as an adjunctive tool for rehabilitation among persons with Severe Mental Illness (SMI).
- Conditions
- Schizophrenia, Schizoaffective, Bipolar Disorder 1
- Trial name
- ESHANTI (NCT05157620)
- Testing
- Yoga-based Exercise (YE), Wellness Lifestyle Program (WLP)
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- VA Office of Research and Development
Major Depressive Disorder, Bipolar I Disorder
Digital Phenotypes for Predicting Depression_Validation
This 12-month, single-site prospective observational study will prospectively monitor the recurrence of mood episodes while continuously collecting passive digital phenotypes in individuals with and without mood disorders.
- Conditions
- Major Depressive Disorder, Bipolar I Disorder, Bipolar II Disorder, Mood Disorders
- Trial name
- NCT07880015
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Schizophrenia, Bipolar Disorder
A Study to Evaluate the Safety and the Effects of Risperidone Compared With Other Atypical Antipsychotic Drugs on the Growth and Sexual Maturation in Children
The purpose of this study is to evaluate the effects of risperidone compared with other atypical antipsychotic drugs on the physical maturity, growth and development of children, and the risk of prolactin-related adverse events…
- Conditions
- Schizophrenia, Bipolar Disorder, Autistic Disorder, Conduct and Other Disruptive Behavior Disorders
- Trial name
- NCT01050582
- Testing
- Risperidone, Other atypical antipsychotic drugs
- Where
- 28 sites in United States, Belgium and 4 more
- Volunteers
- 244 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Bipolar Disorders, Schizophrenia
Injectable Versus Oral Naltrexone Treatment of Alcohol Dependence In Serious Mental Illness (SMI)
The primary aim of this study is to determine the feasibility of long-acting injectable naltrexone administration in a clinical trial in patients with SMI who also have a diagnosis of alcohol dependence.
- Conditions
- Bipolar Disorders, Schizophrenia, Schizoaffective Disorders, Alcohol Dependence
- Trial name
- vivitrol (NCT00453804)
- Testing
- injectable naltrexone, oral naltrexone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- State University of New York - Upstate Medical University
ADHD - Attention Deficit Disorder With Hyperactivity, Bipolar Affective Disorder; Remission in
Psychophysiological Responses to Six Single-Session Self-Regulation Interventions in a Female Adult With ADHD and Stabilized Bipolar Disorder
This study aims to explore how six short, 15-minute self-regulation techniques affect the body and brain in a female adult with ADHD and stabilized bipolar disorder.
- Trial name
- NCT07437833
- Testing
- Moderate-Intensity Aerobic Exercise on Cycloergometer, Cyclic Sighing, Aromatherapy
- Where
- Poland
- Volunteers
- 1 people
- Sponsor
- Poznan University of Physical Education
Bipolar Depression
Dopamine D3 Receptor Occupancy in Bipolar Depression
Bipolar disorder is a common condition that can cause significant disability and risk for suicide. Second generation antipsychotic medications can be used to treat depression in bipolar disorder, yet we do not know how they work.
- Trial name
- NCT05060549
- Testing
- Cariprazine
- Where
- United States
- Sponsor
- New York State Psychiatric Institute
Insomnia, Bipolar Disorder
Add-On Ramelteon in Bipolar I Disorder With Clinically Significant Sleep Disturbance
The purpose of this research study is to evaluate the safety and efficacy of ramelteon (Rozerem™) as an add-on treatment for sleep problems in patients with bipolar disorder.
- Trial name
- NCT00585208
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Lindner Center of HOPE
Humeral Shaft Fracture
Unipolar Versus Bipolar Interlocking in Humeral Shaft Fractures in Adults
Shaft fractures account for 20% of humeral fractures and 3% of all adult fractures in France, with an estimated incidence of 13 to 20/100,000 people.
- Trial name
- UNILOCH (NCT05877014)
- Testing
- questionnaires, scanner
- Where
- France
- Volunteers
- 390 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Bipolar Disorder
Mindfulness Based Cognitive Therapy for Bipolar Disorder
The current study will be a randomized controlled trial (RCT) investigating the clinical and cost-effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) as an adjunct to usual care, versus usual care alone, in reducing…
- Trial name
- MBCT-BD (NCT03507647)
- Testing
- Mindfulness Based Cognitive Therapy, Usual Care
- Where
- 4 sites in Netherlands
- Volunteers
- 144 people
- Sponsor
- Radboud University Medical Center
Bipolar Disorder (BD)
BAROMETRE : Study on the Prognosis and Course of Individuals With Bipolar Spectrum Disorder
Bipolar disorder (BD) is often diagnosed 5 to 10 years after first symptoms, worsening prognosis. "Bipolar At-Risk" (BAR) criteria have been developed to identify people who may be in an early, prodromal stage of BD, but their…
- Trial name
- BAROMETRE (NCT07872878)
- Testing
- Structured clinical follow-up and psychometric assessment
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Smoking, Bipolar Disorder
Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder
This purpose of the study is to develop and test a new website to help people who have bipolar disorder quit smoking.
- Trial name
- WebQuit Plus (NCT02750904)
- Testing
- Experimental plus Nicotine Replacement Therapy, Control plus Nicotine Replacement Therapy
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Fred Hutchinson Cancer Center
Bipolar Disorder
Circadian Rhythm Dysregulation in Offspring of Parents With Bipolar Disorder
This study aims to 1) investigate the differences and variances in circadian rhythms at several levels, including physical activity, dim light melatonin onset, diurnal patterns of cortisol, and body temperature between the…
- Trial name
- NCT03656302
- Where
- Hong Kong
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong