Clinical trials: Biological Clocks
Physiological Stress, Cognitive Dysfunction
DEEPTIME: Human Adaptation in Time Underground Isolation
The objectives of this scientific expedition are: a/ Evaluation of temporal cognitive perception and collective synchronization in a temporally anomalous universe (underground environment), b/ Influence of group living on the…
- Conditions
- Physiological Stress, Cognitive Dysfunction, Sleep
- Trial name
- DEEPTIME (NCT05603780)
- Testing
- exploratory protocol
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Human Immunodeficiency Virus (HIV), Metabolic Dysfunction Associated Steatotic Liver Disease
Tirzepatide's Effects on Epigenetic Aging and Metabolic Restoration in Virally Suppressed People With HIV
This study is a pilot, open-lable, two-arm study. The investigators will enroll virally suppressed people living with HIV and obesity to evaluate the effect of tirzepatide on epigenetic aging, assessed by DNA methylation-based…
- Conditions
- Human Immunodeficiency Virus (HIV), Metabolic Dysfunction Associated Steatotic Liver Disease, Dyslipidaemia, Diabetes Mellitus
- Trial name
- NCT07707778
- Testing
- Tirzepatide
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Clinical Trial Center
Aging
Systemic and Topical Geroprotective Rejuvenation Assessed by START/REST Aging Clocks
This study tests whether certain medicines and a skin treatment can slow down or partly reverse the body's aging process. As people age, the activity of their genes changes in predictable ways.
- Trial name
- NCT07888595
- Testing
- Topical anti-aging peptide serum
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Frontiers in Bioscience Research Institute and Aging
T1DM, Sleep Disorders, Circadian Rhythm
Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes
Type 1 diabetes mellitus (T1DM), makes its appearance during childhood and youth, but management implications last till late adulthood.
- Conditions
- T1DM, Sleep Disorders, Circadian Rhythm, ADHD, Memory Impairment
- Trial name
- NCT04054934
- Testing
- Reversed Circadian Rhythm, Normal Circadian Rhythm
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center