Clinical trials: Bioavailability
Carotenoid, Bioavailability
Effect of Meal Patterning on Carotenoid Absorption From Vegetables
The purpose of this research study is to determine how different meal patterns influence the absorption of beneficial plant pigments (carotenoids) from vegetables.
- Conditions
- Carotenoid, Bioavailability, Dietary Modification
- Trial name
- S26 (NCT01856816)
- Testing
- Meal Pattern Treatment A, Meal Pattern Treatment B, Meal Pattern Treatment C
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Purdue University
Bioavailability
Comparative Bioavailability of Two Forms of Vitamin C
The purpose of this study is to compare levels of vitamin C in the blood over the 24 hour period following a single 1000 mg dose of vitamin C from ascorbic acid, calcium ascorbate and placebo.
- Trial name
- NCT01852903
- Testing
- calcium ascorbate, ascorbic acid
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- NBTY, Inc.
Bioavailability
Fast & Fed Pharmacokinetic (PK) Study
The purpose of this study is to provide information on how well an extended release formulation (a medication that is released and absorbed over a longer period of time than a regular release formulation of the medication) of…
- Trial name
- Keifer (NCT00692016)
- Testing
- Naproxen sodium
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Bioavailability
Urinary Excretion of Anthocyanins During Long Term Blueberry Feeding
Essentially all of the published data on anthocyanin absorption in humans are from short term studies - a few days or less, most typically 24 h.
- Trial name
- NCT01789359
- Testing
- Blueberry Juice
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Atlantic Food and Horticulture Research Center
Bioavailability
Bioavailability of Chemopreventive and Nutritional Compounds in Broccoli
The aim of this study was to determine the absorption of isothiocyanates (ITC) after ingestion of kailan-hybrid broccoli through the analysis of the correspondent urinary biomarkers.
- Trial name
- NCT01743924
- Testing
- raw broccoli
- Where
- Spain
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universidad Politécnica de Cartagena
Bioequivalence, Bioavailability
Bio-equivalence Study
The primary objective of this study is to compare absorption of vitamin K2 (menaquinone-7) after intake of three different vitamin K2 supplements.
- Trial name
- NCT01638143
- Testing
- MenaQ7 M-1500 capsules, Gnosis P-1000 capsules, Gnosis M-1500 capsules
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Bioavailability of Ipragliflozin, Healthy Subjects
Absolute Bioavailability Study With Ipragliflozin
A study to assess the absolute bioavailability of ipragliflozin in healthy subjects.
- Trial name
- NCT01611428
- Testing
- Ipragliflozin
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Healthy Subjects, Bioavailability
A Study to Compare the Bioavailability of 300 mg Trazodone Hydrochloride Extended-release Caplets and 100 mg Trazodone Hydrochloride Immediate-release Tablets at Steady State
The purpose of this study was to compare the pharmacokinetic profiles at steady state of the test product, 300 mg trazodone hydrochloride (HCl) extended-release caplets (containing Contramid®), when administered once daily, and…
- Conditions
- Healthy Subjects, Bioavailability, Pharmacokinetics
- Trial name
- NCT01121926
- Testing
- Trazodone HCl
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Labopharm Inc.
Healthy Subjects, Pharmacokinetics
A Study to Compare the Bioavailability of Two Tramadol Hydrochloride Tablet Products (50 mg and 200 mg, Respectively) at Steady-state Under Fasting Conditions
The purpose of this study was to compare the pharmacokinetic profiles at steady-state of the test product, Tramadol HCl Once-A-Day (OAD) 200 mg tablets and the reference product, Tramadol HCl 50 mg (IR) tablets (Ortho-McNeil…
- Conditions
- Healthy Subjects, Pharmacokinetics, Bioavailability
- Trial name
- NCT00834288
- Testing
- Tramadol HCl
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Labopharm Inc.
Bioavailability
Comparative Bioavailability of Dronabinol Oral Solution Versus Branded Capsule 5 mg Under Fasting Conditions
This is a comparative study to assess bioavailability of a proposed alternate dosage form against the current FDA-approved branded product.
- Trial name
- NCT01448772
- Testing
- Dronabinol Capsules, 5 mg, Dronabinol Oral Solution
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- INSYS Therapeutics Inc
Bioavailability
Bioequivalence Study Between Two Oral Formulations of Famotidine Tablets Under Fasting Conditions
Compare the rate and extent of absorption of famotidine 40 mg tablets, administered as 1 x 40 mg tablet under fasting conditions.
- Trial name
- NCT00802828
- Testing
- Famotidine Tablets, 40 mg
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Perrigo Company
Bioavailability
Bioequivalence Study Between Two Oral Formulations of Famotidine Tablets Under Fed Conditions
Compare the rate and extent of absorption of famotidine 40 mg tablets, administered as 1 x 40 mg tablet under fed conditions.
- Trial name
- NCT00803192
- Testing
- Famotidine Tablets, 40 mg
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Perrigo Company
Bioavailability
Safety, Tolerability and Relative Bioavailability of Pegvisomant in Healthy Subjects
The hypothesis to be tested is that the bioavailability of the new 30-mg vial is similar to that of the current approved 15 -mg vials. In addition, the SC injection using the new 30-mg vial is safe and well-tolerated.
- Trial name
- NCT01181973
- Testing
- pegvisomant
- Where
- Singapore
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pfizer
Bioavailability of ASP015K, Pharmacokinetics of ASP015K
A Single Oral Dose Study of ASP015K in Healthy Volunteers Assessing the Relative Bioavailability Across Three Tablet Strengths From a New Formulation of ASP015K
The purpose of this study is to determine the relative bioavailability and pharmacokinetic profiles from three strengths of a new tablet formulation of ASP015K and to evaluate the safety and tolerability after a single dose of…
- Conditions
- Bioavailability of ASP015K, Pharmacokinetics of ASP015K, Healthy Subjects
- Trial name
- NCT01486017
- Testing
- ASP015K
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Pharmacokinetics of ASP015K, Bioavailability of ASP015K
A Single Oral Dose Study to Compare the Bioavailability Between Two Different Tablet Formulations and Assess if There is a Food Effect With the New Formulation
The purpose of this study is to determine the bioavailability and pharmacokinetics between two different formulations of ASP015K tablets and determine the food effect on the absorption of the new formulation.
- Conditions
- Pharmacokinetics of ASP015K, Bioavailability of ASP015K, Healthy Subjects
- Trial name
- NCT01484964
- Testing
- ASP015K
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Bioavailability
Assess the Influence of a High-fat Meal on the Relative Bioavailability Of Two Formulations of Risedronate
This is a randomized, open-label, multi-center, 4-treatment, 4-period crossover study. Approximately 72 healthy, surgically sterile or postmenopausal subjects will be enrolled and have urine collected over 72 hours following…
- Trial name
- NCT00755872
- Testing
- Risedronate
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Warner Chilcott
Comparative Bioavailability of Clopidogrel Tablets
Comparative Bioavailability Study of Two Oral Formulations of Clopidogrel
Background: Clopidogrel, a potent inhibitor of adenosine diphosphate-induced platelet activation, is widely used to prevent and reduce the risk of thrombotic events.
- Trial name
- NCT01447563
- Testing
- Clopidogrel bisulfate, Clopidogrel
- Where
- Mexico
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Bioavailability of Vitamin B12 From Chicken Eggs
Assessment of Vitamin B12 Bioavailability From Egg
The hypothesis of this study is that chicken eggs can be enriched in vivo with 14C-B12 and fed to healthy human subjects to determine B12 bioavailability from eggs.
- Trial name
- NCT01366937
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Pharmacokinetics, Bioavailability
TMC278-TiDP38-C145: A Bioavailability Study in Healthy Adult Volunteers to Evaluate 3 Pediatric Formulations of TMC278 (a Solution, a Suspension, and Granules) Compared to an Adult Tablet Formulation
The purpose of this study is to evaluate how much and how fast a single, oral, daily 25 mg dose of TMC278 is absorbed into the body when administered as a solution, suspension, granules, or a tablet.
- Conditions
- Pharmacokinetics, Bioavailability, HIV-1
- Trial name
- NCT00812292
- Testing
- TMC278
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Bioavailability
Arabic Gum-Absorption Study
Previous studies have indicated that menaquinone-7 (MK-7) is the most effective form of vitamin K. The Japanese soya product natto is one of the richest food sources of MK-7, but its taste is not appreciated by the Western…
- Trial name
- NCT00858767
- Testing
- menaquinone-7 from casein capsules, menaquinone-7 from arabic gum capsules, menaquinone-7 from linseed oil capsules
- Where
- Netherlands
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center