Clinical trials: Binge-Eating Disorder
Binge Eating Disorder
SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder
The primary objective of the study is to demonstrate the efficacy of SPD489 compared with placebo in adults (18 55 years of age inclusive) with moderate to severe Binge Eating Disorder at Visit 8 (Weeks 11 and 12) as measured by…
- Trial name
- NCT01718509
- Testing
- SPD489 (Lisdexamfetamine dimesylate)
- Where
- 48 sites in United States, Germany
- Volunteers
- 390 people
- Sponsor
- Shire
Binge-Eating Disorder
Uniting Couples in the Treatment of Binge-Eating Disorder
The purpose of this study is to test the feasibility, acceptability, and preliminary effectiveness of a novel couple-based intervention for binge-eating disorder (BED) relative to an established evidence-based individual…
- Trial name
- UNITE (NCT03784820)
- Testing
- UNITE, CBT-E
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of North Carolina, Chapel Hill
Bulimia Nervosa, Binge Eating
Binge Eating & Birth Control
This pilot study examines the effect of stabilizing ovarian hormones on eating behaviors and brain activation in women with binge eating (n=15) using functional magnetic resonance imaging (fMRI) and behavioral tests.
- Conditions
- Bulimia Nervosa, Binge Eating, Eating Disorders, Binge-Eating Disorder
- Trial name
- NCT04278755
- Testing
- Drospirenone-Ethinyl Estradiol Oral Tablet
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of North Carolina, Chapel Hill
Binge Eating Disorder
Open Label Extension in Adults With Binge Eating Disorder (BED)
To evaluate the safety and tolerability of SPD489 administered as a daily morning dose (50 or 70mg) in the treatment of moderate to severe binge eating disorder (BED) in adults
- Trial name
- NCT01657019
- Testing
- Lisdexamfetamine dimesylate
- Where
- 89 sites in United States, Germany and 1 more
- Volunteers
- 604 people
- Sponsor
- Shire
Binge-Eating Disorder
Binge Eating Liraglutide Intervention
The study is a 17-week, single-center, double-blind, parallel-group, randomized placebo controlled trial that will test the efficacy of liraglutide 3.0 mg/d as compared to placebo in reducing the number of binge episodes per…
- Trial name
- BELIEVE (NCT03279731)
- Testing
- Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kelly Allison
Obesity, Overweight
Mobile Attention Retraining in Overweight Female Adolescents
Background: People are constantly exposed to unhealthy foods. Some studies of adults show that training attention away from unhealthy foods might reduce overeating.
- Conditions
- Obesity, Overweight, Binge Eating, Healthy Volunteers
- Trial name
- NCT02977403
- Testing
- Attention Bias Retraining
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Eating Disorders, Binge Eating
Naltrexone Neuroimaging
The purpose of this open-label, pilot study is to evaluate fMRI as a biomarker of opioid antagonism in adolescents with ED. Modulation of brain activation will be examined in regions of interest by fMRI using a food-specific and…
- Conditions
- Eating Disorders, Binge Eating, Purging (Eating Disorders)
- Trial name
- EDIT-N2 (NCT04935931)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Children's Mercy Hospital Kansas City
Anorexia Nervosa/Bulimia, Anorexia in Adolescence
Oral Naltrexone In Pediatric Eating Disorders
The objective of this study is to evaluate the effectiveness of oral naltrexone tablets in pediatric and adolescent eating disorders, in particular anorexia nervosa and bulimia nervosa, as compared to placebo.
- Conditions
- Anorexia Nervosa/Bulimia, Anorexia in Adolescence, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- ONPED (NCT05073679)
- Testing
- Naltrexone Hydrochloride, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rosemary Claire Roden
Alcohol Drinking, Alcohol Use Disorder
Understanding Alcohol Reward in Social Context
In this study, the investigators examine whether emotional and social reward from alcohol varies depending on the social context of consumption.
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use
- Trial name
- NCT03449095
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Binge Eating, Type 2 Diabetes
FoodSteps for Binge Eating & Food Insecurity
The purpose of this study is to conduct a pilot trial of a mobile intervention that targets binge eating and weight-related behaviors, to determine the feasibility, acceptability, and preliminary efficacy of the intervention…
- Conditions
- Binge Eating, Type 2 Diabetes, Food Insecurity
- Trial name
- NCT06348251
- Testing
- FoodSteps
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Northwestern University
Binge Eating Disorder
A Study to Evaluate a Drug (Dasotraline) on the Safety, Effectiveness and How Well the Body Tolerates it, in Adults With Moderate to Severe Binge Eating Disorder
A study to evaluate a drug (dasotraline) on the safety, effectiveness and how well the body tolerates it, in adults with moderate to severe binge eating disorder
- Trial name
- NCT03107026
- Testing
- dasotraline 4mg, dasotraline 6mg
- Where
- 50 sites in United States
- Volunteers
- 491 people
- Sponsor
- Sumitomo Pharma America, Inc.
Binge-Eating Disorder
Acceptance-based Group Intervention for Binge Eating
This study proposes to compare a brief Acceptance and Commitment Therapy (ACT) group intervention to an active control group in a sample of 154 overweight or obese binge eating Veterans who have completed the VA's national…
- Trial name
- NCT01757847
- Testing
- Acceptance and Commitment Therapy (ACT), Brief MOVE-II control group intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Binge-Eating Disorder, Obesity
Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Maintenance Treatment
This study will test the effectiveness of lisdexamfetamine (LDX) medication as a maintenance therapy for the treatment of binge-eating disorder (BED) in patients with obesity.
- Trial name
- NCT03926052
- Testing
- Lisdexamfetamine Dimesylate
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Yale University
Binge-Eating Disorder
Multicenter Study to Evaluate the Efficacy and Safety of Oral ACT-539313 in the Treatment of Adults With Moderate to Severe Binge Eating Disorder
Placebo-controlled study to evaluate the efficacy and safety of oral ACT-539313 in the treatment of adults with moderate to severe binge eating disorder
- Trial name
- NCT04753164
- Testing
- ACT-539313
- Where
- 30 sites in United States
- Volunteers
- 136 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Alcohol; Use, Problem, Stress
A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use.
- Conditions
- Alcohol; Use, Problem, Stress, Binge Eating, Depression
- Trial name
- NCT04038190
- Testing
- behavioral activation
- Where
- United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Binge-eating Disorder, Obesity
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Acute Treatment
This study will test the effectiveness and relative efficacy of behavioral and pharmacologic treatments, alone and in combination, for the treatment of binge eating disorder (BED) in patients with obesity.
- Trial name
- NCT03045341
- Testing
- NB medication (Naltrexone Bupropion combination), Behavioral Weight Loss (BWL) counseling
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Yale University
Stress Disorders, Post-Traumatic, Bulimia Nervosa
Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD
This research is being done to find out how effective Prazosin is in the treatment of bulimic patients experiencing distressing nightmares using subjective and objective measures.
- Trial name
- NCT02382848
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Milton S. Hershey Medical Center
Binge Eating Disorder
Dasotraline Binge Eating Disorder Extension Study
Binge Eating Disorder Extension Study.
- Trial name
- NCT02684279
- Testing
- Dasotraline
- Where
- 57 sites in United States
- Volunteers
- 533 people
- Sponsor
- Sumitomo Pharma America, Inc.
Overweight, Eating Disorders
Adding Guided Self-Help Group Therapy to the Alli Weight Loss Program in Treating Binge Eating Disorder
This study will evaluate the effectiveness of adding guided self-help group therapy to a weight loss program in achieving weight loss and reducing binge eating in overweight binge eaters.
- Trial name
- NCT00601354
- Testing
- Emotion regulation group therapy, Orlistat/alli program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Stanford University
Eating Disorders
Leveraging Social Media to Identify and Connect Teens With Eating Disorders to a Mobile Guided Self-Help Mobile Intervention
Clinical or subclinical eating disorders (EDs) impact 10% of individuals in their lifetime and are marked by significant functional impairment, early mortality, chronicity, and emotional distress.
- Trial name
- NCT04636840
- Testing
- Space From Body and Eating Concerns- Teen
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- Washington University School of Medicine