Clinical trials: Binge-Eating Disorder
Eating Disorders, Binge Eating
Naltrexone Neuroimaging
The purpose of this open-label, pilot study is to evaluate fMRI as a biomarker of opioid antagonism in adolescents with ED. Modulation of brain activation will be examined in regions of interest by fMRI using a food-specific and…
- Conditions
- Eating Disorders, Binge Eating, Purging (Eating Disorders)
- Trial name
- EDIT-N2 (NCT04935931)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Children's Mercy Hospital Kansas City
Feeding and Eating Disorders
Web-based Guided Self-help CBT-E vs Online G-CBT-E for Binge Eating Behavior
Eating disorders with binge eating as the core feature include bulimia nervosa (BN) and binge eating disorder (BED). In recent years, the prevalence rate has increased rapidly, mostly among women, accompanied by emotional…
- Trial name
- NCT05873127
- Testing
- web-based guided self-help Enhanced Cognitive Behavioral therapy, online Enhanced Cognitive Behavioral therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Mental Health Center
Anorexia Nervosa/Bulimia, Anorexia in Adolescence
Oral Naltrexone In Pediatric Eating Disorders
The objective of this study is to evaluate the effectiveness of oral naltrexone tablets in pediatric and adolescent eating disorders, in particular anorexia nervosa and bulimia nervosa, as compared to placebo.
- Conditions
- Anorexia Nervosa/Bulimia, Anorexia in Adolescence, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- ONPED (NCT05073679)
- Testing
- Naltrexone Hydrochloride, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rosemary Claire Roden
Eating Disorders, Anorexia Nervosa
Preparing for Eating Disorders Treatment Through Compassionate Letter-Writing
Compassion-focused therapy (CFT) seeks to lower shame and help people develop compassion for personal distress and shortcomings.
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- NCT04174703
- Testing
- Self-compassionate letter-writing intervention
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Waterloo
Alcohol Drinking, Alcohol Use Disorder
Understanding Alcohol Reward in Social Context
In this study, the investigators examine whether emotional and social reward from alcohol varies depending on the social context of consumption.
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use
- Trial name
- NCT03449095
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Eating Disorders, Anorexia Nervosa
Eating Disorder Dynamic Intervention
The goal of this study is to develop and test a digital program to help people with eating disorders in their everyday lives. The program uses brief surveys and sensor data collected by smartphones to understand when someone may…
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder
- Trial name
- EDDI (NCT07600671)
- Testing
- Eating Disorder Dynamic Intervention
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Trustees of Dartmouth College
Anorexia Nervosa, Bulimia Nervosa
Inhibitory Control and Eating Disorders
Executive functions are part of the high-level cognitive processes essential to the proper functioning of human cognition. They consist mainly of flexibility, updating and inhibition.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Binge Eating
- Trial name
- InhibEating (NCT03850288)
- Testing
- Neuropsychological assessment : Stroop task, Neuropsychological assessment : Go No Go task
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Hospices Civils de Lyon
Binge Eating, Type 2 Diabetes
FoodSteps for Binge Eating & Food Insecurity
The purpose of this study is to conduct a pilot trial of a mobile intervention that targets binge eating and weight-related behaviors, to determine the feasibility, acceptability, and preliminary efficacy of the intervention…
- Conditions
- Binge Eating, Type 2 Diabetes, Food Insecurity
- Trial name
- NCT06348251
- Testing
- FoodSteps
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Northwestern University
Binge Eating Disorder
A Study to Evaluate a Drug (Dasotraline) on the Safety, Effectiveness and How Well the Body Tolerates it, in Adults With Moderate to Severe Binge Eating Disorder
A study to evaluate a drug (dasotraline) on the safety, effectiveness and how well the body tolerates it, in adults with moderate to severe binge eating disorder
- Trial name
- NCT03107026
- Testing
- dasotraline 4mg, dasotraline 6mg
- Where
- 50 sites in United States
- Volunteers
- 491 people
- Sponsor
- Sumitomo Pharma America, Inc.
Eating Disorders, Bulimia Nervosa
Effectiveness of Baclofen in the Treatment of People With Bulimia Nervosa or Binge Eating Disorder
This study will evaluate the effectiveness of the drug baclofen in reducing binge eating and associated food cravings in people with bulimia nervosa or binge eating disorder.
- Trial name
- NCT00320047
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York State Psychiatric Institute
Binge-Eating Disorder
Acceptance-based Group Intervention for Binge Eating
This study proposes to compare a brief Acceptance and Commitment Therapy (ACT) group intervention to an active control group in a sample of 154 overweight or obese binge eating Veterans who have completed the VA's national…
- Trial name
- NCT01757847
- Testing
- Acceptance and Commitment Therapy (ACT), Brief MOVE-II control group intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Eating Disorders, Psychiatric Comorbidities
Structural Brain Volumetry Changes in Eating Disorders.
The goal of this observational study is to investigate the relationship between structural brain changes and psychiatric comorbidities in individuals diagnosed with eating disorders (EDs).
- Trial name
- NCT07131852
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Eating Disorders, Anorexia Nervosa
Pilot Intervention for Social Biases in Eating Disorders
Both behavioral, psychological, and cognitive differences related to social cognitive function have been related to illness-state in eating disorders, but interventions that directly target these problems are limited.
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- SBPI (NCT04877158)
- Testing
- Self-Blame and Perspective-Taking Intervention
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Texas Southwestern Medical Center
Binge Eating, Purging (Eating Disorders)
Emotion Regulation in Binge Eating and Purging Among Adolescents
The study will examine the neural and behavioral correlates of emotion regulation in adolescents engaging in binge eating and/or purging and healthy adolescents.
- Trial name
- NCT03429114
- Testing
- Magnetic resonance imaging
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Stanford University
Type 2 Diabetes Mellitus, Binge-Eating Disorder
Preventing Type 2 Diabetes in Black Emergent Adult
Black Americans are disproportionately affected by diabetes, with nearly double the rates of type 2 diabetes mellitus (T2DM), compared to non-Hispanic White adults.
- Conditions
- Type 2 Diabetes Mellitus, Binge-Eating Disorder, Binge Eating, Obesity
- Trial name
- NCT06848244
- Testing
- Appetite Awareness Training (AAT), Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Binge-Eating Disorder, Emotion Regulation
Profiling the Dynamic of Binge Eating Disorder (PRODY-BED)
The goal of this observational study is to explore if different and specific profiles can be identified in adults with binge eating disorder (BED) depending on their additional eating pathology, emotion regulation and executive…
- Conditions
- Binge-Eating Disorder, Emotion Regulation, Executive Dysfunction, Eating Behavior
- Trial name
- PRODY-BED (NCT05726721)
- Testing
- Treatment as usual, Psychotherapy
- Where
- 3 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- Aarhus University Hospital
Binge Eating Behaviour, Binge Eating/Loss of Control Eating
Impact of the EXOMIND (BTL-699-2) on the Brain Reward Pathway
The goal of this clinical trial is to thoroughly explore and ascertain the mechanism of action of the therapy with the EXOMIND (BTL-699-2) device in the treatment of food cravings (serving as an important precipitant to binge…
- Conditions
- Binge Eating Behaviour, Binge Eating/Loss of Control Eating, Food Craving
- Trial name
- NCT07024550
- Testing
- Treatment with BTL-699-2 device, Treatment with BTL-699-2 device with intensity below therapeutic threshold
- Where
- Czechia
- Volunteers
- 8 people
- Sponsor
- BTL Industries Ltd.
Bulimia Nervosa, Binge Eating Disorder
Using Visual Feedback to Influence Rapid Response in the Treatment of Eating Disorders
This study has two aims: 1) to test the validity of an eating disorder symptom checklist against an established clinical interview; and 2) to examine whether providing eating disorder patients with visual graphs of their symptom…
- Trial name
- NCT02940613
- Testing
- Visual feedback of symptom frequency
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Binge Eating Disorder, Obesity
Meditation-Based Treatment for Binge Eating Disorder
The purpose of this study is to assess the relative effectiveness of a mindfulness meditation-based intervention for binge eating disorder in comparison to a psycho-educational intervention and a waiting-list control group.
- Trial name
- NCT00032760
- Testing
- Meditation
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Pregnancy Weight Gain, Eating Disorders
A Single Session Self-guided Acceptance-based Digital Intervention Targeting Food Cravings in Pregnancy
Pregnancy is a time of heightened risk for disordered eating behaviors, which have been linked to adverse health outcomes in gestation, delivery, and the postpartum.
- Conditions
- Pregnancy Weight Gain, Eating Disorders, Perinatal Problems, Binge Eating
- Trial name
- NCT06129461
- Testing
- Single-session acceptance-based online workshop targeting food cravings as predictors of loss of control and binge eating in pregnancy
- Volunteers
- 130 people
- Sponsor
- University at Albany