Clinical trials: Bilateral Cerebral Palsy
Periventricular Leukomalacia
Telerehabilitation of Working Memory in Children With Periventricular Leukomalacia and Bilateral Cerebral Palsy
Periventricular Leukomalacia (PVL) is a white matter lesion surrounding the lateral ventricles of the brain occurring in the prenatal period, associated with a disorder of movement and posture, known as bilateral cerebral palsy.
- Trial name
- NCT02342990
- Testing
- Cluster B CogMed: an home-based and computer-based solution to improve working memory deficit, Cluster A No training. Delay start of CogMed
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Fondazione Stella Maris
Bilateral Cerebral Palsy
Horizontal Versus Vertical Upper Extremity Function in Bilateral Cerebral Palsy
The goal of this quasi-experimental study is to investigate and compare the effects of horizontal and vertical upper extremity performance on hand skills and trunk control in children with bilateral spastic cerebral palsy; could…
- Trial name
- NCT07367477
- Testing
- a designed occupational therapy program to improvement hand skills conducted on a vertical surface., a designed occupational therapy (OT) program to improvement hand skills conducted on a horizontal surface.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Raghda Gamal Ateya Abd-Elbary
Hemiplegic Cerebral Palsy
Use of Joystick-operated Ride-on-toys to Improve Affected Arm Use and Function in Children With Hemiplegic Cerebral Palsy
This research is being done to explore if modified, commercially available, joystick-operated, ride-on-cars can be used to promote bilateral arm function in children with hemiplegic Cerebral Palsy (CP).
- Trial name
- NCT05559320
- Testing
- Ride-on-toy navigation training, Upper extremity functional training
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Connecticut
Bilateral Cerebral Palsy
Effects of Physical Training Following Selective Dorsal Rhizotomy on Non-ambulant Children With Bilateral Spastic Cerebral Palsy
Children with spastic bilateral cerebral palsy are late developers. delayed gross and fine motor development require early intervention to improve the child performance and avoid secondary impairments.
- Trial name
- NCT05006144
- Testing
- physical therapy excercises, Standard Orthotic Management, selective dorsal rhizotomy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Unilateral and Bilateral Cerebral Palsy
Quality of Life in Children With Cerebral Palsy
Cerebral Palsy (CP) is an umbrella term that defines a group of permanent disorders of movement and posture, happening during the developing foetal or infant brain.
- Trial name
- NCT06288958
- Testing
- Quality of Life and social participation in Italian children with CP
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Fondazione Stella Maris
Cerebral Palsy
Unilateral Versus Bilateral Lower-Limb Plyometric Training in Children With Cerebral Palsy
This study was set out to compare the effect of paretic-limb-only plyometric training versus double-limb training on balance capability and gait symmetry in adolescents with unilateral cerebral palsy (U-CP).
- Trial name
- NCT05302102
- Testing
- Unilateral plyometric training, Bilateral plyometric training, Standard physical therapy
- Where
- Saudi Arabia
- Volunteers
- 69 people
- Sponsor
- Cairo University
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cerebrovascular Accident, Hemiplegia
Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments
The purpose of this study was to determine the effect of two amounts of treatment therapy on post stroke motor recovery in the arms.
- Trial name
- NCT00369668
- Testing
- Bilateral movements and neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Cerebral Palsy
Changes Induced by Early HABIT-ILE in Pre-school Children With Uni- and Bilateral Cerebral Palsy
Studying in two randomized controlled trials (RCT) the changes induced by early HABIT-ILE in functional, neuroplastic and biomechanical assessment in children with unilateral and bilateral CP.
- Trial name
- EarlyHABIT-ILE (NCT04020354)
- Testing
- HABIT-ILE, Usual Care
- Where
- 3 sites in Belgium, France and 1 more
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain
Complete or Incomplete Paraplegia/quadriplegia, Spinal Cord Injury
Research on Wireless Brain Implant System for General Control of External Devices
The clinical trial aims to evaluate the safety and efficacy of the minimally invasive, wireless brain-machine interface system (WRS) in enabling general brain control of external devices, such as a cursor and other assistive…
- Conditions
- Complete or Incomplete Paraplegia/quadriplegia, Spinal Cord Injury, Brainstem Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- RISE (NCT06829212)
- Testing
- WRS
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Shanghai StairMed Technology Co., Ltd.
Cerebral Palsy
Functional and Neuroplastic Effects of HABIT-ILE in Children With Bilateral Cerebral Palsy
This randomized controlled trial will compare the effects of neuroplastic and functional changes of Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) when presented in two periods (2HG; n=24) versus a…
- Trial name
- FuN HABIT-ILE (NCT06428032)
- Testing
- Hand-Arm Bimanual Intensive Therapy Including Lower Extremities
- Where
- Chile
- Volunteers
- 48 people
- Sponsor
- Universidad Nacional Andres Bello
Cerebral Palsy
Functional Effects and Impact on Motor Neuronal Activity of Early and Intensive Motrice (Hand and Arm Bimanual Intensive Therapy Including Lower Extremities: HABIT-ILE) Reeducation in Children With Pre-school Bilateral Cerebral Palsy
One of the urgent priorities in the field of pediatric neuro-rehabilitation is the development of efficient early motor interventions for children with cerebral palsy (CP).
- Trial name
- MOOV (NCT04362800)
- Testing
- MRI, Electro-Encephalography-High Density, 3D and EMG analysis
- Where
- 2 sites in France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Brest
Cerebral Palsy
Effect of Designed Physical Training After Selective Dorsal Rhizotomy on Motor Function of Ambulant Children With Spastic Diplegia
The management of cerebral palsy is complex and requires a multidisciplinary approach. Selective dorsal rhizotomy is a neurosurgical technique that aims to reduce spasticity in the lower limbs and improve motor function.
- Trial name
- NCT04997044
- Testing
- Concomitant physical rehabilitation, Standard Orthotic Management, selective dorsal rhizotomy
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Erector Spinae Plane Block, Opioid
Bilateral Erector Spinae Plane Block as an Opioid Sparing Technique for Selective Dorsal Rhizotomy in Pediatric Patients With Spastic Cerebral Palsy
This study aims to evaluate the efficacy of bilateral erector spinae plane block as an opioid-sparing technique for selective dorsal rhizotomy in pediatric patients with spastic cerebral palsy.
- Conditions
- Erector Spinae Plane Block, Opioid, Sparing, Selective Dorsal Rhizotomy
- Trial name
- NCT06600061
- Testing
- Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy
Effects of WALKBOT-G Robot-assisted Gait Training on Anticipatory Posture Adjustment Function and Balance With Cerebral Palsy
In children with cerebral palsy, the quality of walking decreases due to a decrease in the ability to control limbs, including walking, and coordination among various activities of daily living due to a decrease in functional…
- Conditions
- Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy, Bilateral Spastic Cerebral Palsy, Gait Disorders, Neurologic
- Trial name
- NCT04884386
- Testing
- robot-assisted gait training, conventional locomotion therapy
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Sahmyook University
Bilateral Spastic Cerebral Palsy
Kinesio Taping Versus Electrical Stimulation on Dysphagia in Bilateral Cerebral Palsy
The purpose of this study will be to compare the effect between kinesiotaping and neuromuscular electrical stimulation on dysphagia in children with bilateral spastic cerebral palsy.
- Trial name
- NCT07695350
- Testing
- Structured Oromotor Exercises, Kinesio Taping, Neuromuscular Electrical Stimulation
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Children, Cerebral Palsy
Reliability and Validity of Strength Measurements of the Lower Limbs in Children With Bilateral Spastic Cerebral Palsy.
Specific musculo-tendinous adaptations in children with cerebral palsy (CP) have an influence on muscle strength and consequently on functional behavior and participation.
- Conditions
- Children, Cerebral Palsy, Muscle Weakness
- Trial name
- NCT03818152
- Testing
- Functional strength assessment
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- University Ghent
Hemiplegia, Cerebral Palsy
Bimanual Training in Children With Hemiplegia
A randomized control trial of bimanual training in children with hemiplegia. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement…
- Conditions
- Hemiplegia, Cerebral Palsy, Children
- Trial name
- HABIT (NCT01413594)
- Testing
- HABIT
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Stroke, Cerebral Palsy
Usability Testing of a Bilateral Activities of Daily Exercise Robot for Stroke Therapy
In stroke rehabilitation, unilateral training of the impaired limb after stroke is often the frequent strategy used over bilateral ones.
- Trial name
- BiADLER (NCT02882646)
- Testing
- Bi-ADLER
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Orthopedic Complications in Cerebral Palsy
Cohort of Children With Severe Cerebral Palsy
" Cohort CP " is a multicentre cohort study, initiated by the Hospices Civils de Lyon in September 2009. Population targeted are children with bilateral cerebral palsy, level GMFCS IV or V, aged from 2 to 10 years at inclusion.
- Trial name
- CPCohort (NCT01840930)
- Where
- France
- Volunteers
- 385 people
- Sponsor
- Hospices Civils de Lyon