Clinical trials: Bifurcation
Cardiovascular Diseases
Safety Study to Assess the Feasibility of Use in Humans of the TAXUS Petal Bifurcation Coronary Stent System
The purpose of this study is to determine the safety and feasibility of use in humans of the TAXUS Petal Paclitaxel-Eluting Bifurcation Coronary Stent System in the treatment of de novo lesions in native coronary arteries…
- Trial name
- NCT00497367
- Testing
- Percutaneous Coronary Intervention (PCI) TAXUS Petal
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 28 people
- Sponsor
- Boston Scientific Corporation
Coronary Artery Disease
Study Examining the PROMUS Element Everolimus-eluting Stent in Multi-center Coronary Intervention of Complex Arterial Lesion Subsets
Randomized trials have demonstrated an excellent safety and efficacy profile for the chromium everolimus-eluting stent. The platinum chromium everolimus-eluting sten (PtCr-EES) uses the identical antiproliferative agent and…
- Trial name
- SPECIALIST (NCT01670318)
- Testing
- platinum chromium everolimus-eluting stent (PROMUS Element by Boston Scientific, Massachusetts)
- Where
- 38 sites in Japan
- Volunteers
- 800 people
- Sponsor
- The PCI Guideline Research Society
Aortoiliac Occlusive Disease
Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used in Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) to Treat Aortoiliac Occlusive Disease
The study will assess the safety and effectiveness of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis ("VBX Device" or also referred to as "VBX Stent Graft") in a post approval setting and evaluate the quality of the use…
- Trial name
- NCT06872905
- Testing
- GORE VIABAHN® VBX Balloon Expandable Endoprosthesis (VBX)
- Where
- 26 sites in United States, Italy and 3 more
- Volunteers
- 158 people
- Sponsor
- W.L.Gore & Associates
Wide Neck Bifurcation Intracranial Aneurysms
Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device
A prospective, multicenter, single arm, interventional study. The target patient population for this study are adult subjects with WNBAs of the anterior and posterior intracranial circulation.
- Trial name
- WEB PAS (NCT04839705)
- Testing
- WEB
- Where
- 27 sites in United States
- Volunteers
- 195 people
- Sponsor
- Microvention-Terumo, Inc.
Coronary Bifurcation Lesion, Coronary Artery Disease (CAD)
Crossover vs Accurate Ostial PCI for Medina 0.0.1 and 0.1.0 Left Main Bifurcation Lesions
Coronary artery disease is a leading cause of mortality and morbidity globally. The left coronary artery system is critically important due to its supply of a large area of myocardium.
- Conditions
- Coronary Bifurcation Lesion, Coronary Artery Disease (CAD), Left Main Coronary Artery Stenosis
- Trial name
- NCT07596706
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Istanbul Mehmet Akif Ersoy Educational and Training Hospital
Coronary Artery Disease, Coronary Stenosis
Ultrathin DES in Complex PCI Scenarios: the ULTRA a Multicenter Study
ULTRA is a multicenter, observational, retrospective registry, enrolling consecutive patients treated with ultrathin coronary DES (coronary stent with strut thickness < 70 um) for coronary bifurcation lesions, left main disease…
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Stent Restenosis, Left Main Coronary Artery Disease
- Trial name
- ULTRA (NCT05205148)
- Testing
- Percutaneous coronary intervention with the following platforms: Orsiro; Mistent; BioMime; Supraflex Cruz
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Ankle/Foot Surgery
Ultrasound Guided Popliteal Fossa Block. Does Blockade Distal to Sciatic Nerve Bifurcation Speed Onset Time? A Prospective, Randomized Trial
Sciatic nerve block is used routinely in ankle and foot surgery. It is applied often by a posterior approach at the popliteal fossa, near where the nerve divides into the common peroneal and tibial nerves.
- Trial name
- NCT00803426
- Testing
- Sciatic nerve blockade for ankle/foot surgery
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University Health Network, Toronto
Coronary Artery Disease, Restenosis
Culotte Technique Versus TAP Stunting for the Treatment of de Novo Coronary Bifurcation Lesion With Drug-eluting Stents
BBK- 2 - study: STUDY-SUMMARY Background: The need for stenting of the main and side branch (double stenting) in the treatment of coronary bifurcation lesion primarily depends on the complexity of the bifurcation lesion.
- Trial name
- BBK2 (NCT01267838)
- Testing
- PCI
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Coronary Artery Disease
RESOLUTE ONYX Post-Approval Study (Bifurcation Cohort)
To observe the continued performance of the Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System in a real-world more-comer population.
- Trial name
- NCT03584464
- Testing
- Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
- Where
- 25 sites in United States, Belgium and 2 more
- Volunteers
- 205 people
- Sponsor
- Medtronic Vascular
Coronary Artery Disease
Bingo Drug-eluting Balloon Versus a Drug-eluting Stent for Coronary Bifurcation Lesions
Bingo drug-eluting balloon versus a drug-eluting stent for coronary bifurcation lesions: a prospective, multi-center, randomized, non-inferiority trial
- Trial name
- NCT06441539
- Testing
- Bingo® Paclitaxel coated balloon, Xience® Alpine Everolimus Eluting Coronary Stent System
- Volunteers
- 218 people
- Sponsor
- Yinyi(Liaoning) Biotech Co., Ltd.
Femoral Bifurcation Surgery
Development of a Predictive Score for Local Complications of Femoral Bifurcation Surgery
No prospective study has yet evaluated the factors influencing the complications of femoral bifurcation surgery in France. Daily practice of investigators suggests that conventional surgical treatment has had a higher rate of…
- Trial name
- PROFA (NCT03772821)
- Testing
- Data collection, Incision/scar measurement
- Where
- 7 sites in France
- Volunteers
- 163 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Intracranial Aneurysms
The Reverse Barrel™ VRD Intracranial Aneurysm Trial
The purpose of this clinical investigation is to evaluate the safety and effectiveness of the Barrel™ VRD when used to facilitate endovascular coiling of wide-neck bifurcating or branch intracranial aneurysms with any approved…
- Trial name
- Barrel (NCT02125097)
- Testing
- Barrel™ Vascular Reconstruction Device (VRD)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Complex Left Main Bifurcation Stenosis, Left Main Coronary Artery Stenosis
COMPETE-LM Trial: Drug-Coated Balloon-Enhanced Provisional Stenting in Complex Left Main Disease.
Prospective, physician-initiated, multicenter, randomized, single-blind, controlled trial. Participants will be randomized (1:1) to a DCB-enhanced strategy (study group) or a conventional strategy (control group).
- Conditions
- Complex Left Main Bifurcation Stenosis, Left Main Coronary Artery Stenosis, Coronary Bifurcation Stenosis
- Trial name
- COMPETE-LM (NCT07408674)
- Testing
- Angiolite Sirolimus-Eluting Stenting, Essential Pro Paclitaxel Drug-Eluting Balloon
- Volunteers
- 186 people
- Sponsor
- Rede Optimus Hospitalar SA
Coronary Artery Disease
DES Versus BiOSS LIM - POLBOS II Study
Coronary bifurcation lesions pose therapeutic problems during percutaneous coronary interventions (PCI) and are associated with higher rates of periprocedural complications as well as higher rates of in-stent restenosis and stent…
- Trial name
- POLBOS II (NCT02198300)
- Testing
- Coronary angioplasty with stent implantation, Dual antipletlet therapy (DAPT)
- Where
- Poland
- Volunteers
- 202 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Stent Restenosis, Stent Thrombosis
veRy Thin Stents for Patients With Left mAIn or bifurcatioN in Real Life: the RAIN a Multicenter Study
For permanent coronary stents, reduction of thickness of struts have become one of the most important innovation, being related to easier manipulation, reduced risk of stent thrombosis and low rate of revascularization.
- Conditions
- Stent Restenosis, Stent Thrombosis, Left Main Coronary Artery Disease, Coronary Bifurcations
- Trial name
- RAIN (NCT03544294)
- Testing
- Xience alpine, ultimaster, resolute onyx, synergy
- Where
- Italy
- Volunteers
- 2,800 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Angioplasty, Percutaneous Coronary Intervention
Palpitate-Eluting Balloon Angioplasty in the Treatment of Coronary Bifurcation Lesion Evaluated by OCT
The aim of the study is to use optical coherence tomography (OCT) to investigate the efficacy of Paclitaxel-eluting PTCA-balloon dilation (SeQuent Please) in SB and drug eluting stent (EXCEL stent) deployment in the main branch…
- Trial name
- PEBCBLO (NCT02276846)
- Testing
- Paclitaxel-Eluting Balloon
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Hospital of Jilin University
Coronary Arterial Disease (CAD)
Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for De Novo Coronary Bifurcation Lesions
Evaluating the Safety and Efficacy of Sirolimus-coated Coronary Balloon Dilatation Catheter vs Paclitaxel-coated balloon catheter for the Treatment of De Novo Coronary Bifurcation Lesions
- Trial name
- NCT06822712
- Testing
- Sirolimus-coated Balloon Dilatation Catheter, Paclitaxel-coated Balloon Dilatation Catheter
- Where
- China
- Volunteers
- 250 people
- Sponsor
- BrosMed Medical Co., Ltd
Coronary Disease
Safety and Efficacy Study of the Nile PAX Drug-Eluting Coronary Bifurcation Stent
The purpose of this trial is to assess the safety and efficacy of the Nile PAX® Drug Eluting Coronary Bifurcation Stent System for the treatment of single de novo bifurcation lesions in native coronary arteries with a main branch…
- Trial name
- BIPAX (NCT01308229)
- Testing
- Nile PAX® paclitaxel-eluting coronary stent
- Where
- 10 sites in Brazil, Bulgaria and 5 more
- Volunteers
- 102 people
- Sponsor
- MINVASYS
Coronary Bifurcation Lesion
LATAM Bif Registry
The LATAM Bif Registy is an international and prospective registry of percutaneous coronary interventions (PCI) in coronary bifurcation lesions.
- Trial name
- NCT04471883
- Testing
- Percutaneous coronary interventions
- Volunteers
- 5,000 people
- Sponsor
- LATAM Bifurcation Club
Coronary Artery Disease
Choice Of Optimal Strategy For Bifurcation Lesions With Normal Side Branch
Few data are available about the late patency of side branches in association with the currently used stent types and implantation techniques.
- Trial name
- CROSS (NCT00694005)
- Testing
- kissing balloon, without kissing balloon angioplasty "leave alone"
- Where
- 11 sites in South Korea
- Volunteers
- 504 people
- Sponsor
- Seung-Jung Park