Clinical trials: Bifurcation
Popliteal Nerve Block, Foot Surgery
Continuous Popliteal Nerve Blocks: Effect of Perineural Catheter Tip Location Relative to the Sciatic Nerve Bifurcation on Postoperative Analgesia
Research study to determine the relationship between perineural catheter tip location relative to the sciatic nerve bifurcation and postoperative analgesia for continuous popliteal nerve blocks.
- Conditions
- Popliteal Nerve Block, Foot Surgery, Ankle Surgery, Popliteal Bifurcation
- Trial name
- NCT01229696
- Testing
- Catheter Placed At Bifurcation, Catheter Placed 5cm Above Bifurcation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Diego
Root Perforation at the Bifurcation Area, Strip Perforation
Evaluation for Healing of Iatrogenic Perforation After Non Surgical Repair
The goal of this retrospective study is to evaluate the outcome of nonsurgical root perforation repair treated by specialized endodontist .
- Conditions
- Root Perforation at the Bifurcation Area, Strip Perforation, Lateral Perforation
- Trial name
- NCT06991569
- Testing
- Non-surgical perforation repair
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Mohamed Salah Elwakeel
Ischemic Heart Disease
Comparison of Results Achieved by Different Ballooning Techniques in Bifurcation Stenting
Single-stent strategy with provisional approach represents the gold standard for percutaneous coronary intervention of bifurcation lesions, and, according to European Bifurcation Club, performing provisional approach presents two…
- Trial name
- CRABBIS (NCT05559424)
- Testing
- OCT
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Catholic University of the Sacred Heart
Coronary Bifurcations
CELTIC Bifurcation Study
This study will examine outcomes for patients treated by planned culotte stenting and compare outcomes with 2 different stent platforms, the next generation Synergy II and the Xience Xpedition DES platforms.
- Trial name
- NCT02232815
- Where
- 6 sites in Ireland, United Kingdom
- Volunteers
- 170 people
- Sponsor
- European Cardiovascular Research Center
Ischaemic Heart Disease, Ischemic Heart Disease
The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)
The purpose is to compare median two-year clinical outcome after OCT guided vs. standard guided revascularization of patients requiring complex bifurcation stent implantation
- Trial name
- OCTOBER (NCT03171311)
- Testing
- Angiographic guided PCI, OCT guided PCI
- Where
- 38 sites in Belgium, Denmark and 11 more
- Volunteers
- 1,201 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Arterial Disease (CAD)
Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for De Novo Coronary Bifurcation Lesions
Evaluating the Safety and Efficacy of Sirolimus-coated Coronary Balloon Dilatation Catheter vs Paclitaxel-coated balloon catheter for the Treatment of De Novo Coronary Bifurcation Lesions
- Trial name
- NCT06822712
- Testing
- Sirolimus-coated Balloon Dilatation Catheter, Paclitaxel-coated Balloon Dilatation Catheter
- Where
- China
- Volunteers
- 250 people
- Sponsor
- BrosMed Medical Co., Ltd
Angina Pectoris, Angina, Unstable
Intravascular Near Infrared Spectroscopy (NIRS) Bifurcation - Lipid Core Plaque Shift Study
This pilot study is going to examine the hypothesis that in coronary arteries, soft lesions that contain lipid cores, but are not calcified or fibrotic and are located in proximity to side branches, are associated with side…
- Conditions
- Angina Pectoris, Angina, Unstable, Atherosclerosis, Coronary Artery Disease
- Trial name
- NCT00905671
- Testing
- LipiScan Coronary Imaging Catheter
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Infraredx
Coronary Bifurcation Lesions, Death
Mini-Crush Or Controlled Balloon-Crush For True Coronary Bifurcation Lesions
The mini-crush technique is one of the leading 2-stent techniques frequently applied by interventional cardiologists to treat complex bifurcation lesions.
- Conditions
- Coronary Bifurcation Lesions, Death, Myocardial Infarction (MI), Stent Thrombosis
- Trial name
- NCT06880978
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Istanbul Mehmet Akif Ersoy Educational and Training Hospital
Coronary Artery Disease
Study Examining the PROMUS Element Everolimus-eluting Stent in Multi-center Coronary Intervention of Complex Arterial Lesion Subsets
Randomized trials have demonstrated an excellent safety and efficacy profile for the chromium everolimus-eluting stent. The platinum chromium everolimus-eluting sten (PtCr-EES) uses the identical antiproliferative agent and…
- Trial name
- SPECIALIST (NCT01670318)
- Testing
- platinum chromium everolimus-eluting stent (PROMUS Element by Boston Scientific, Massachusetts)
- Where
- 38 sites in Japan
- Volunteers
- 800 people
- Sponsor
- The PCI Guideline Research Society
Hypertension, Carotid Stenosis
Reconstruction of the Carotid Bifurcation in Patients With Arterial Hypertension of 2-3 Degrees
Carotid endarterectomy (CEA) is a well-established procedure for preventing ischemic brain damage. Stenosis of the precerebral vessels are often combined with arterial hypertension.
- Conditions
- Hypertension, Carotid Stenosis, Symptomatic Carotid Artery Stenosis
- Trial name
- NCT05931003
- Testing
- Carotid stenting, Carotid endarterectomy
- Where
- Russia
- Volunteers
- 90 people
- Sponsor
- Samara State Medical University
Coronary Ostium Stenosis, Myonecrosis
Side Branch Predilatation Strategy in Coronary Bifurcation Lesion Stenting (SBPS)
The role of Side Branch (SB) predilatation during coronary bifurcation lesion percutaneous coronary intervention (PCI) is still not established.
- Trial name
- SBPS (NCT01430377)
- Testing
- SB predilatation, No SB predilatation
- Where
- Bulgaria
- Volunteers
- 120 people
- Sponsor
- Medica Cor Heart Hospital
Periprocedural Myonecrosis
Intracoronary Electrocardiogram (ECG) and Myonecrosis After Bifurcation Stenting
The coronary bifurcation lesions pose a therapeutic problem with high rates of periprocedural complications, higher rates of in-stent restenosis and stent thrombosis.
- Trial name
- COSIBRIA&CO (NCT01268228)
- Where
- 3 sites in Bulgaria, Poland
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University National Heart Hospital
Coronary Bifurcation Lesions
Sirolimus DEB in Coronary Bifurcation Lesions
The purpose of this study is to evaluate the efficacy and safety of sirolimus drug-eluting coronary balloon catheter in treatment of coronary bifurcation lesions.
- Trial name
- NCT04896177
- Testing
- Sirolimus drug-eluting coronary balloon catheter, Paclitaxel drug-eluting coronary balloon catheter
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
Coronary Stenosis
POLish Bifurcation Optimal Treatment Strategy Study for Left Main Bifurcation Percutaneous Coronary Intervention (PCI)
The primary objective of this study is to study the safety and efficacy of the BiOSS LIM C with respect to Patient oriented Composite Endpoint (PoCE) at 12 months in a "real world" left-main bifurcation population and as compared…
- Trial name
- POLBOS-LM (NCT03508219)
- Testing
- BiOSS LIM C
- Where
- 15 sites in France, Italy and 1 more
- Volunteers
- 130 people
- Sponsor
- ECRI bv
Left Main Coronary Artery Disease
Mini Crush or Double Kissing Crush Stenting Techniques For Complex Left Main Bifurcation Lesions
The Crush technique has evolved significantly since its introduction to the literature by Colombo et al in 2003, with multiple iterations including mini-crush (MC) and double kissing-crush (DKC) stenting techniques.
- Trial name
- NCT06546748
- Where
- Turkey (Türkiye)
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Istanbul Mehmet Akif Ersoy Educational and Training Hospital
Coronary Artery Disease
Simple Crossover Versus Side Branch Opening in Patients With Non-Left Main Bifurcation Lesion
Hypothesis: Simple crossover strategy would be non-inferior to SB opening strategy in the risk of target lesion failure (TLF) in patients with angiographically compromised SB (visually SB stenosis ≥50%) after provisional MV…
- Trial name
- CROSS-COBIS (NCT05705362)
- Testing
- Simple Crossover, Side branch opening
- Volunteers
- 1,000 people
- Sponsor
- Keimyung University Dongsan Medical Center
Ischemia; Heart, Stents
Immediate and Short Term Outcomes for Using Drug Coated Balloons in Treating Coronary Bifurcation Lesions
● the investigators aims to study the impact of using drug coated balloon in coronary artery bifurcation lesions on the procedural success rate \& short-term MACE.
- Trial name
- DCB (NCT05872074)
- Testing
- Coronary angiography plus percutenous coronary intervention
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Atherosclerosis, Coronary
Fluid-dynamics in Bifurcation PCI
Investigator-initiated, international, multicentre, observational study with two cohorts. The two study cohorts will be: Cohort A: to understand if the local blood flow patterns (associated with low WSS), as evaluated by…
- Trial name
- FORECAST (NCT03174418)
- Testing
- Coronary angiography and optical coherence tomography
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Catholic University of the Sacred Heart
Coronary Heart Disease
The Study of Active Transfer of Plaque Technique for Non-Left Main Coronary Bifurcation Lesions
A Prospective Multi-center Randomized Trial Assessing the Efficacy and Safety of Active Transfer of Plaque vs. Provisional T Stenting for the Treatment of Non-Left-Main Coronary Bifurcation Lesions.
- Trial name
- NCT02768116
- Testing
- Sirolimus Drug-eluting Stent via Active Transfer of Plaque, Sirolimus Drug-eluting Stent implantation via Provisional T Stenting
- Volunteers
- 316 people
- Sponsor
- Beijing Anzhen Hospital
STEMI - ST Elevation Myocardial Infarction, Unstable Angina
Evaluation of Short Term Outcome of Different Bifurcation Stenting Techniques at Assuit University Cath. Lab
Primary aim: evaluation of the short term outcome of different techniques used in bifurcational coronary arteries intervention regarding major adverse cardiac event (MACE): cardiac death, myocardial infarction, target vessel…
- Trial name
- NCT03266289
- Volunteers
- 50 people
- Sponsor
- MA Abdelreheem