Clinical trials: Bifurcation
Coronary Disease
Safety and Efficacy Study of the Nile PAX Drug-Eluting Coronary Bifurcation Stent
The purpose of this trial is to assess the safety and efficacy of the Nile PAX® Drug Eluting Coronary Bifurcation Stent System for the treatment of single de novo bifurcation lesions in native coronary arteries with a main branch…
- Trial name
- BIPAX (NCT01308229)
- Testing
- Nile PAX® paclitaxel-eluting coronary stent
- Where
- 10 sites in Brazil, Bulgaria and 5 more
- Volunteers
- 102 people
- Sponsor
- MINVASYS
Coronary Atherosclerosis
Bifurcation Lesion Analysis and STenting / BLAST
The purpose of this research study is to determine if Intravascular Ultrasound (IVUS) grayscale and VH (Virtual Histology)-IVUS pre-stenting can assess more accurately the location, amount, and type of a blockage than angiogram…
- Trial name
- BLAST (NCT02316782)
- Testing
- Blinded IVUS assessment, Nonblinded IVUS
- Where
- 10 sites in United States, Denmark and 6 more
- Volunteers
- 195 people
- Sponsor
- Volcano Corporation
Coronary Arterial Disease (CAD)
Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for De Novo Coronary Bifurcation Lesions
Evaluating the Safety and Efficacy of Sirolimus-coated Coronary Balloon Dilatation Catheter vs Paclitaxel-coated balloon catheter for the Treatment of De Novo Coronary Bifurcation Lesions
- Trial name
- NCT06822712
- Testing
- Sirolimus-coated Balloon Dilatation Catheter, Paclitaxel-coated Balloon Dilatation Catheter
- Where
- China
- Volunteers
- 250 people
- Sponsor
- BrosMed Medical Co., Ltd
Angina Pectoris, Angina, Unstable
Intravascular Near Infrared Spectroscopy (NIRS) Bifurcation - Lipid Core Plaque Shift Study
This pilot study is going to examine the hypothesis that in coronary arteries, soft lesions that contain lipid cores, but are not calcified or fibrotic and are located in proximity to side branches, are associated with side…
- Conditions
- Angina Pectoris, Angina, Unstable, Atherosclerosis, Coronary Artery Disease
- Trial name
- NCT00905671
- Testing
- LipiScan Coronary Imaging Catheter
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Infraredx
Coronary Bifurcation Lesions
Sirolimus DEB in Coronary Bifurcation Lesions
The purpose of this study is to evaluate the efficacy and safety of sirolimus drug-eluting coronary balloon catheter in treatment of coronary bifurcation lesions.
- Trial name
- NCT04896177
- Testing
- Sirolimus drug-eluting coronary balloon catheter, Paclitaxel drug-eluting coronary balloon catheter
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
Coronary Stenosis
POLish Bifurcation Optimal Treatment Strategy Study for Left Main Bifurcation Percutaneous Coronary Intervention (PCI)
The primary objective of this study is to study the safety and efficacy of the BiOSS LIM C with respect to Patient oriented Composite Endpoint (PoCE) at 12 months in a "real world" left-main bifurcation population and as compared…
- Trial name
- POLBOS-LM (NCT03508219)
- Testing
- BiOSS LIM C
- Where
- 15 sites in France, Italy and 1 more
- Volunteers
- 130 people
- Sponsor
- ECRI bv
Coronary Artery Disease
A Study of the Cypher Sirolimus-Eluting Stent to Treat Bifurcation Lesions.
The objective of this study is to assess the feasibility and safety of the sirolimus-coated Bx VELOCITY Balloon-Expandable Stent in treating patients with true bifurcation lesions.
- Trial name
- BIFURCATION (NCT00234455)
- Testing
- drug eluting-stent, drug-eluting stent
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- Cordis US Corp.
Coronary Bifurcation Lesions
ACOART SCB BIF: Treatment of Coronary Bifurcation Lesion by Sirolimus Coated Balloon vs Paclitaxel Coated Balloon
The aim of this randomized controlled trial is to examine the treatment of coronary bifurcation lesion with a sirolimus coated balloon versus a paclitaxel coated balloon.
- Trial name
- NCT04899583
- Testing
- Sirolimus Coated Balloon Catheter, a Paclitaxel Coated Balloon Catheter
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Acotec Scientific Co., Ltd
Coronary Artery Disease
Frontier Registry II Bifurcation Stent System Registry
To assess the procedural success, performance, 30-day and 6 month clinical outcome of bifurcation stenting, and the six month incidence of clinically indicated target lesion revascularization with the use of the Abbott Vascular…
- Trial name
- NCT00286195
- Testing
- Multi-Link Frontier Coronary Stent System
- Sponsor
- Abbott Medical Devices
Coronary Atherosclerosis of Native Coronary Artery, Bifurcation Lesions: de Novo Lesions of the Main and Side Branch of Native Coronary Artery
Prospective, Single Blind, Rand Controlled Study to Evaluate the Safety & Effectness of Tryton Side Branch Stent Used With DES Treatmt of de Novo Bifurcation Lesions in MB & SB in Native Coronaries
The Tryton Side Branch Stent System has been designed to address the procedural difficulty surrounding treatment of bifurcation lesions and to ensure patency of the side branch with similar performance capabilities (e.g.…
- Trial name
- TRYTON (NCT01258972)
- Testing
- Tryton Side Branch Stent with main branch DES, POBA
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Tryton Medical, Inc.
Aneurysm, Intracranial
An EFS Assessing the Electrolytic eCLIPs System for Treatment of Intracranial Aneurysms
The purpose of this study is to investigate the feasibility and initial clinical safety of eCLIPs device use for the treatment of wide-necked bifurcation aneurysms.
- Trial name
- NCT04886505
- Testing
- Electrolytic eCLIPs Bifurcation System
- Sponsor
- Evasc Medical Systems Corp.
Aorto-iliac Aneurysms, Iliac Aneurysms
PRESERVE-Zenith® Iliac Branch System Clinical Study
The PRESERVE-Zenith® Iliac Branch System Clinical Study is a clinical trial to study the safety and effectiveness of the Zenith® Branch Endovascular Graft-Iliac Bifurcation in combination with the Zenith® Connection Endovascular…
- Trial name
- NCT01208415
- Testing
- Endovascular repair for aortoiliac or iliac aneurysms.
- Where
- 19 sites in United States
- Volunteers
- 40 people
- Sponsor
- Cook Group Incorporated
Coronary Bifurcation Lesion
Efficacy and Safety of Sirolimus-Coated Spiral Balloon for Coronary Bifurcation Lesions
This is a multicenter, prospective randomized controlled study to evaluate the safety and effectiveness of Sirolimus-coated spiral balloon (SuperFlow®) versus Paclitaxel-coated balloon (Bingo™) in the treatment of coronary…
- Trial name
- NCT06618248
- Testing
- Sirolimus coated balloon angioplasty, Paclitaxel coated balloon angioplasty
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Dongguan TT Medical
Saccular Aneurysm, Intracranial Aneurysm
European eCLIPS™ Safety, Feasibility and Efficacy Study
An open label, prospective, multicentre, single-arm, post marketing study evaluating the safety, technical feasibility, and efficacy of the eCLIPs™ Family of Products for the treatment of bifurcation intracranial aneurysms.
- Trial name
- EESIS (NCT02607501)
- Testing
- Implant eCLIPs
- Where
- 4 sites in Denmark, Germany and 1 more
- Volunteers
- 20 people
- Sponsor
- Evasc Medical Systems Corp.
Brain Aneurysm
Safety Study of the PulseRider® in Patients Undergoing Treatment for Bifurcation Intracranial Aneurysms
This is a prospective multi-center, single arm, non-randomized study. It is designed to evaluate the safety of the PulseRider® in patients undergoing treatment for bifurcation intracranial aneurysms.
- Trial name
- AWARD (NCT02435823)
- Testing
- PulseRider
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Pulsar Vascular
Cardiovascular Disease, Coronary Artery Occlusion
Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients
The NAGOMI COMPLEX PMCF (Post-Market Clinical Follow-up) study has been designed to expand the knowledge about outcomes with the Ultimaster Nagomi™ sirolimus eluting coronary stent system (Ultimaster Nagomi™) in complex PCI…
- Conditions
- Cardiovascular Disease, Coronary Artery Occlusion, Ischemic Heart Disease
- Trial name
- NAGOMI COMPLEX (NCT05705973)
- Testing
- Ultimaster Nagomi™
- Where
- 52 sites in Austria, Belgium and 11 more
- Volunteers
- 3,000 people
- Sponsor
- Terumo Europe N.V.
Coronary Artery Disease
RESOLUTE ONYX Post-Approval Study (Bifurcation Cohort)
To observe the continued performance of the Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System in a real-world more-comer population.
- Trial name
- NCT03584464
- Testing
- Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
- Where
- 25 sites in United States, Belgium and 2 more
- Volunteers
- 205 people
- Sponsor
- Medtronic Vascular
Aortoiliac Aneurysms, Iliac Aneurysms
PRESERVE-Zenith® Branch Endovascular Graft-Iliac Bifurcation Clinical Study
The purpose of this extended study is to evaluate the safety and effectiveness of the Zenith® Branch Endovascular Graft-Iliac Bifurcation in combination with the commercially available Atrium iCAST™ covered stent in patients in a…
- Trial name
- NCT02571907
- Testing
- Zenith® Branch Endovascular Graft-Iliac Bifurcation,, Atrium iCAST™, Zenith® Flex AAA Endovascular Graft
- Where
- 28 sites in United States
- Volunteers
- 40 people
- Sponsor
- Cook Research Incorporated
Intracranial Aneurysms
Canadian eCLIPs™ Safety and Feasibility Study Protocol
The purpose of this study is to evaluate the safety and feasibility of the eCLIPs™ Family of Products for the treatment of unruptured intracranial bifurcation aneurysms in conjunction with embolization coils.
- Trial name
- CESIS (NCT01957683)
- Testing
- eCLIPs™ Family of Products
- Where
- 5 sites in Canada
- Sponsor
- Evasc Medical Systems Corp.
Unruptured Wide-neck Intracranial Aneurysms
A Study Evaluating the Safety and Effectiveness of the PulseRider® Aneurysm Neck Reconstruction Device Used in Conjunction With Endovascular Coil Embolization in the Treatment of Wide-Neck Bifurcation Intracranial Aneurysm
This is a prospective, multi-center, non-randomized clinical evaluation utilizing the PulseRider® Aneurysm Neck Reconstruction Device.
- Trial name
- NAPA (NCT03383666)
- Testing
- PulseRider® Aneurysm Neck Reconstruction Device
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Pulsar Vascular