Clinical trials: Benign Prostatic Hyperplasia (BPH)
Prostatic Hyperplasia, Prostate Enucleation
Bipolar Transurethral Enucleation Versus Resection in the Treatment of Benign Prostatic Hyperplasia: a Comparative Study
Benign prostatic hyperplasia (BPH) is a common chronic progressive disease resulting in the enlargement of the prostate gland and bladder outlet obstruction in aging men .
- Trial name
- NCT06294366
- Testing
- Bipolar Bowa device
- Where
- Egypt
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Benign Prostatic Hypertrophy With Outflow Obstruction, Overactive Detrusor
Prognostic Value of the Urinary Nerve Growth Factor in the Patients With Benign Prostatic Hyperplasia
Persistent detrusor overactivity (DO) after transurethral prostatectomy results in symptomatic failure in more than one third of the patients.
- Trial name
- NCT01781117
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Holmium laser enucleation system and morcellator
- Where
- South Korea
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- KYU-SUNG LEE
Bladder Outlet Obstruction
An Open Label Study to Measure Efficacy of Fesoterodine (Toviaz) Post Surgery for Benign Prostatic Hyperplasia
The subjects who have symptoms of overactive bladder (many trips to the bathroom, and urgency with or without the inability to hold your urine until you get to the toilet) are invited to participate in this research study.
- Trial name
- Toviaz (NCT00605319)
- Testing
- Toviaz (Fesoterodine)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Bladder Injury, Prostate Hyperplasia
Anatomic Endoscopic Prostate Enucleation and BICEP Classification
The Bladder Injury Classification System for Endoscopic Procedure (BICEP) is designed to provide a systematic framework for categorizing bladder injuries that occur during endoscopic procedures.
- Trial name
- BICEP (NCT06469125)
- Testing
- Endoscopic Prostate Interventions for Anatomic Enucleation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Prostatic Hyperplasia
The Effect of Using a Motivation Card on Pain and Number of Walking Steps After Prostate Surgery
The purpose of this clinical study is to evaluate the effect of using motivational cards on pain and step counts in patients who underwent open prostate surgery due to benign prostatic hyperplasia.The main hypotheses are: H1…
- Trial name
- NCT06699563
- Testing
- Mobilization Motivation Card
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trakya University
Prostatic Hyperplasia
Bioavailability of Two Combination Products of Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) in Asian Males.
This study aims to determine the relative bioavailability of tamsulosin hydrochloride in a fixed dose combination capsule of dutasteride and tamsulosin hydrochloride (0.5 mg/0.2 mg) relative to co-administration of dutasteride…
- Trial name
- ARI115707 (NCT01471678)
- Testing
- Dutasteride (0.5mg), FDC product of dutasteride (0.5mg) and tamsulosin HCl (0.2mg), Harnal D Tablets and Harnal Capsules (both comprising 0.2 mg tamsulosin HCl)
- Where
- Australia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Ejaculation Abnormal, BPH With Urinary Obstruction
Ejaculation Preserving Photoselective Vaporization Versus Plasma Kinetic Vaporization Versus Transurethral Resection Of The Prostate: A RCT
To Evaluate and compare the outcome and coast of ejaculation sparing management of BPH using 3 different techniques: PVP, PKVP and TURP. Ejaculation sparing TURP group is considered the standard control group.
- Conditions
- Ejaculation Abnormal, BPH With Urinary Obstruction, Prostatic Hyperplasia, Prostate Disease
- Trial name
- EPPROSTATECT (NCT03589196)
- Testing
- Ejaculation Preserving Photoselective Vaporization, Ejaculation Preserving Plasma Kinetic Vaporization, Ejaculation Preserving Transurethral Resection Of The Prostate
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Prostate Disease, Malignancy
Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain
Transrectal prostate biopsy is a commonly performed ambulatory procedure for diagnosing prostate cancer. Prostate biopsy are associated with pain or anxiety.
- Conditions
- Prostate Disease, Malignancy, Benign Prostatic Hyperplasia, Prostate Cancer
- Trial name
- NCT05803096
- Testing
- Self-Administered Nitrous Oxide, Oxygen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Benign Prostatic Hyperplasia (BPH)
PK Comparison of GL2701 With Finasteride and Tamsulosin in Combination
To compare the relative bioavailability and pharmacokinetic characteristics of a newly single pill combination of finasteride and tamsulosin with a conventional combination of finasteride and tamsulosin in healthy subjects with a…
- Trial name
- NCT01829893
- Testing
- In combination of 0.2mg finasteride and 5mg tamsulosin, GL2701 capsule
- Where
- South Korea
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Melatonin, Cognitive Dysfunction
Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia
This study aims to evaluate the possible effect of melatonin on prevention of cognitive dysfunction in the postoperative period of elderly patients undergoing transurethral resection of the prostate (TURP) under spinal anesthesia
- Conditions
- Melatonin, Cognitive Dysfunction, Postoperative Complications, Prostate Hyperplasia
- Trial name
- NCT03966950
- Testing
- melatonin
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
BPH, Prostate Hyperplasia
MRI Guided Transrectal Prostate Laser Ablation for Benign Prostatic Hypertrophy (BPH)
Over 100,000 BPH procedures are performed annually in the US. The purpose of this study is to evaluate the effectiveness of performing MRI guided transrectal laser ablation using a 980 nm laser (VisualaseTM by Medtronic, Inc., a…
- Conditions
- BPH, Prostate Hyperplasia, Urinary Frequency/Urgency
- Trial name
- NCT03131544
- Testing
- MRI Guided Transrectal Periuretheral Transitional Zone Ablation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Prostate Laser Center, PLLC
Benign Prostate Hypertrophy(BPH), Prostate Cancer (Adenocarcinoma)
Investigation of the Diagnostic Role of miRNAs in PCa and BPH
Prostate cancer(PCa) is the second most common cause of cancer-related death in men after lung cancer. Diagnostic methods such as measurement of serum Prostate-specific antigen (PSA) levels used in the clinic still cannot…
- Trial name
- NCT06726070
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Benign Prostate Hypertrophy(BPH)
A Clinical Trial to Compare and Evaluate Evaluate the Pharmacokinetics and Safety of CKD-846
A Clinical trial to compare and evaluate evaluate the pharmacokinetics and safety of CKD-846
- Trial name
- NCT06110923
- Testing
- CKD-846, D091
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Prostatic Hyperplasia
Bioequivalence - Duodart Against Avodart & Omnic
Open-label, randomized, single dose, two-treatment, two-way crossover study
- Trial name
- NCT01657851
- Testing
- dutasteride/tamsulosin, dutasteride, tamsulosin
- Where
- Russia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Benign Prostatic Hyperplasia
A Clinical Trial to Evaluate the Bioequivalence of AD-116A and AD-1161 Under Fed Conditions in Healthy Adult Male Volunteers
This study compares and evaluates the bioequivalence of AD-116A and AD-1161 in healthy adult male volunteers under fed conditions.
- Trial name
- NCT07722871
- Testing
- AD-116A, AD-1161
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
LUTS, Benign Prostatic Hyperplasia
Investigate the Effect of Food on the Pharmacokinetic of JLP-1207 in Healthy Male Volunteers
The purpose of this study is to investigate the pharmacokinetic drug interaction between Solifenacin and Tamsulosin in healthy male volunteers.
- Conditions
- LUTS, Benign Prostatic Hyperplasia, Overactive Bladder
- Trial name
- NCT02447367
- Testing
- JLP-1207(Fasted), JLP-1207(Fed)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Prostatic Hyperplasia
Prostatic Hyperplasia Treatment and Cancer Prevention
Treatment of patients with prostatic hyperplasia with topical papaverine.
- Trial name
- NCT03064282
- Testing
- papaverine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Manchanda Medical Clinic
Prostatic Hyperplasia
Bioavailability Study of Fixed Dose Combination (FDC) Dutasteride and Tamsulosin Hydrochloride (HCl) Relative to One Dutasteride and One Tamsulosin HCl Tablet in Healthy Male Subjects
The primary objective of this study is to determine the bioavailability of a FDC capsule formulation of dutasteride and tamsulosin hydrochloride (0.5 milligram [mg]/0.2 mg) relative to coadministration of one dutasteride 0.5 mg…
- Trial name
- NCT02509104
- Testing
- FDC capsule of dutasteride and tamsulosin, Dutasteride soft gelatine capsule and tamsulosin HCl oral disintegrating tablet
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Benign Prostatic Hyperplasia
Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer.
Many patients may face long-term urinary side effects following stereotactic body radiation therapy (SBRT), including increased urinary frequency, dysuria, and nocturia.
- Trial name
- NCT05148156
- Testing
- Urolift
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwell Health