Clinical trials: Behavioral Difficulties, open to volunteers
Autism Spectrum Disorder
Dialectic Behaviour Therapy (DBT) for People With Autism: A Multiple Baseline Single Case Design
The goal of this experimental study is to test the effectiveness of Dialectic Behavioural Therapy in patients with Autism Spectrum Disorder. The aim questions are: 1.
- Trial name
- DGT-ASS (NCT07786883)
- Testing
- Dialectic Behavioural Therapy
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- GGZ Friesland
Language Delay, Language Development
Combined Oral Motor Stimulation and Language on Preterm Infant Feeding
This is a randomized controlled trial to study an oromotor stimulation in combination with a reading curriculum in the NICU among preterm infants using oral muscle exercises, Language Environment Analysis (LENA) recordings…
- Conditions
- Language Delay, Language Development, Feeding; Difficult, Newborn, Mother-Infant Interaction
- Trial name
- NCT05861531
- Testing
- Oromotor stimulation, Reading curriculum, LENA recording
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Anxiety, Depression
Emotion Focused Family Therapy for Parents of Children With Mental Health Difficulties
Emotion Focused Family Therapy (EFFT) is a promising intervention that aims to teach parents advanced skills to support their child's development of emotion skills and increase their adaptive behaviours, potentially leading to…
- Conditions
- Anxiety, Depression, Behavior Problem
- Trial name
- NCT05603000
- Testing
- Emotion Focused Family Therapy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Guelph
Depression - Major Depressive Disorder, Depression Bipolar
Mental Health Mission Mood Disorder Cohort Study
The current study aims to understand why some people with depression respond to treatment and others do not, using markers of clinical symptoms, both clinician reported outcome measures and patient reported outcome measures…
- Conditions
- Depression - Major Depressive Disorder, Depression Bipolar, Treatment Resistant Depression
- Trial name
- NCT07189689
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- University of Oxford
Vision and Hearing Loss, Vision Impairment
SENSE-Brain Health Pro for Older Adults With Sensory Loss
The goal of this study is to learn about the outcomes, usability, and accessibility of the online Brain Health Pro program for older adults with hearing difficulties, vision difficulties, or both.
- Conditions
- Vision and Hearing Loss, Vision Impairment, Hearing Impairment, Vision Difficulty
- Trial name
- SENSE-BHPro (NCT07856888)
- Testing
- Brain Health Pro
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Université de Montréal
ADHD - Combined Type, ADHD Predominantly Inattentive Type
NeuroTrainer Cognitive Training For Academic Focus
This clinical trial aims to evaluate the feasibility and efficacy of NeuroTrainer cognitive training in improving attentional and executive control functions in students with and without attention-related difficulties.
- Conditions
- ADHD - Combined Type, ADHD Predominantly Inattentive Type, ADHD, Predominantly Hyperactive - Impulsive
- Trial name
- NCT06512974
- Testing
- NeuroTrainer
- Where
- 3 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- NeuroTrainer
Peripheral Artery Disease, Exercise
Response to Exercise and Nitric Oxide in PAD
RESIST PAD is a randomized trial of 200 PAD patients to establish: 1) whether a 12-week exercise intervention significantly increases Δ nitrite at 12-week follow-up, compared to control; 2) whether exercise "responders" have…
- Conditions
- Peripheral Artery Disease, Exercise, Intermittent Claudication, Nitric Oxide
- Trial name
- RESIST (NCT06657976)
- Testing
- Supervised Treadmill Exercise, Attention Control, Nitrate-Rich Beetroot Juice + supervised exercise therapy
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Depressive Disorder, Emotional Dysregulation
Music Therapy for Adolescents with Emotional Difficulties
The goal of this clinical trial is to examine the effects of a music therapy program in adolescents aged 13-18 years old with emotional difficulties, primarily depression and possibly concurrent diagnoses of anxiety.
- Trial name
- NCT06733883
- Testing
- psychotherapy
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Listening Difficulties
Causes of Listening Difficulties in Children
Many children experience listening and processing difficulties (LiD), especially in background noise, despite normal hearing sensitivity. The prevalence of these problems is estimated at 0.5-1% in the general population.
- Trial name
- CLINIC (NCT06388343)
- Testing
- Evaluation of Children's Listening and Processing Skills, Multidisciplinary behavioral assessment
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Mental Health Help-Seeking, Mental Health Difficulties
YOUCA App for Parents of Children With Mental Health Issues: A Pilot Study of Usability and Efficacy
Parents play an important role in supporting their children's mental health but often feel unsure how to respond to emotional or mental health difficulties.
- Conditions
- Mental Health Help-Seeking, Mental Health Difficulties, Mental Health and General Well-being
- Trial name
- YOUCA (NCT07766746)
- Testing
- App YOUCA (prototype)
- Where
- Austria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hochschule Campus Wien (University of Applied Sciences Campus Vienna)
Preventive Intervention, Mental Health Difficulties
The STIME Project: Intersectoral Prevention of Severe Youth Mental Health Difficulties
This randomized controlled trial aims to evaluate the effectiveness of participation in five different STIME (Strengthened Cross-Sectoral Initiative for Children and Young People's Mental Health) interventions: 'Signs of…
- Trial name
- STIME (NCT07413887)
- Testing
- 'Signs of Disordered Eating', 'Signs of Self-Harm', 'Signs of Internalizing'
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Center for Clinical Research and Prevention
Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary
Physical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment
Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France.
- Conditions
- Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty
- Trial name
- CMT1A-HOME (NCT07591779)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Feeding Difficulties, Sucking Behavior
Premature Infant Oral Motor Intervention vs. Pacifier for Oral Feeding Transition in Preterm Infants
This study compares three approaches to help premature babies learn to feed by mouth: a special mouth exercise program (called PIOMI), using a pacifier, and standard care.
- Conditions
- Feeding Difficulties, Sucking Behavior, Premature
- Trial name
- PIOMI (NCT07460089)
- Testing
- Premature Infant Oral Motor Intervention (PIOMI), Pacifier Use (Non-Nutritive Sucking)
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- University of Baghdad
Mental Health, Oral Health Care
The Mouth Matters in Mental Health Trial -2
This clinical trial will evaluate the effectiveness and cost-effectiveness of a link work intervention for supporting people with severe mental health difficulties to attend a routine dental appointment.
- Conditions
- Mental Health, Oral Health Care, Psychosis
- Trial name
- NCT07470437
- Testing
- Link work intervention
- Where
- 5 sites in United Kingdom
- Volunteers
- 480 people
- Sponsor
- Lancashire and South Cumbria NHS Foundation Trust
Disruptive Behavior, Behavior Problems
A Randomized Controlled Trial on Brief Behavioral Parent Training
RATIONALE: The access to and uptake of evidence-based behavioral parent training for children with behavioral difficulties (i.e., oppositional, defiant, aggressive, hyperactive, impulsive, and inattentive behavior) are currently…
- Conditions
- Disruptive Behavior, Behavior Problems, Behavioral Problems, Problem Behaviors
- Trial name
- PAINT-GGZ (NCT05591820)
- Testing
- Brief behavioral parent training with optional booster sessions, Care as usual
- Where
- Netherlands
- Volunteers
- 93 people
- Sponsor
- Accare
Insomnia, Cognitive Dysfunction
Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)
This randomized controlled trial will evaluate the impact of an Internet-delivered cognitive behavioral therapy for insomnia (CBT-I) intervention on sleep and the extent to which it contributes to cognitive health in individuals…
- Conditions
- Insomnia, Cognitive Dysfunction, Mild Cognitive Impairment, Sleep Initiation and Maintenance Disorders
- Trial name
- NCT05565833
- Testing
- SHUTi OASIS, Patient Education
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Virginia
Breastfeeding
Nynnamm - Effects of Infant Directed Singing on Breastfeeding Difficulties
Breastfeeding is one of the most effective, health economical interventions to promote health and reduce illness in both mothers and children. However, breastfeeding in Sweden is under threat.
- Trial name
- Nynnamm (NCT06085989)
- Testing
- Infant directed singing, Standard care
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Dalarna University
Reintegration Difficulties, Suicidal Ideation and Behaviors
Expanding Veteran Sponsorship Initiative+ to Support High-Risk Transitioning Servicemembers and Veterans: A Precision Medicine Approach
Background Young Veterans in the U.S. face a heightened risk of suicide, particularly during the first year after leaving military service-a period often referred to as the "deadly gap." Suicide rates among Veterans aged 18 to 34…
- Conditions
- Reintegration Difficulties, Suicidal Ideation and Behaviors, Health, Connectedness
- Trial name
- NCT07356492
- Testing
- Onward Ops- receive peer sponsor and community support, VA stepped care services
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Feeding and Eating Disorders of Childhood, Appetite Disorders
Biolizin for Improving Functional Poor Appetite in Children Aged 6 to 36 Months (CTBE2502)
Functional poor appetite is common in young children and may be linked to suboptimal micronutrient intake and feeding behavior. This study evaluates whether a zinc-containing oral supplement (Biolizin syrup) can improve eating…
- Conditions
- Feeding and Eating Disorders of Childhood, Appetite Disorders, Functional Poor Appetite
- Trial name
- CTBE2502 (NCT07153549)
- Testing
- Biolizin, Standardized caregiver counseling on responsive feeding
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Depression, Cancer
Trajectories of Anxiety and Depression in Cancer Patients, Risk and Predictive Factors and Supportive Care; Prognostic Awareness and Shared Decision Making.
To examine the trajectories of anxiety and depression symptoms over the course of oncological disease, and to assess potential predictors-sociodemographic (age, sex, marital status, employment status), clinical (tumor location…
- Conditions
- Depression, Cancer, Anxiety
- Trial name
- NCT07168096
- Testing
- Psychosocial and clinical assessment
- Where
- 18 sites in Spain
- Volunteers
- 540 people
- Sponsor
- Fundación Sociedad Española de Oncologia Médica