Clinical trials: Behavior Problems
LGBTQ, Sexual Behavior
Developing Online Interventions to Reduce Stigma-Related Stress, Sexual Health, and HIV Risk Among Young Chinese MSM
This study is a 2-arm RCT that will assess the efficacy of a culturally adapted, 10-session SGM-affirmative, internet-based cognitive behavioral therapy (iCBT) among young men who have sex with men (YMSM) in Hunan province China.
- Conditions
- LGBTQ, Sexual Behavior, HIV Risk
- Trial name
- NCT04718194
- Testing
- ESTEEM iCBT, Self-monitoring control
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Drinking, Alcohol Abuse
Promoting Self-Change From Alcohol Problems: Mechanisms of Change in a Community-Based Intervention
Research has found that natural recovery (self-change) is a very common pathway to change for individuals with alcohol problems, accounting for nearly 75% of recoveries in several national surveys.
- Trial name
- PSC3 (NCT00732095)
- Testing
- Promoting Self-Change with Ads
- Where
- United States
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Mental Health
Nurse-led Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I) in University Students With Mild to Moderate Mental Health Problems
This study aims to evaluate the feasibility, acceptability, and potential effectiveness of a nurse-led digital cognitive behavioral therapy for insomnia (dCBT-I) via large language model based-chatbot among university students…
- Trial name
- NCT07711769
- Testing
- Brief sleep health advice, 2 weeks of chatbot-based daily sleep diary, 10 weeks chatbot-based IM support
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder, Earthquake
The Effect of Parent Mediated Intervention Program on Children With ASD Exposed to Earthquake in Turkey in February 2023
After devastating natural events such as earthquakes, individuals with special needs experience much more difficulties. There is a limited number of studies investigating the impact of disasters on individuals with autism.
- Conditions
- Autism Spectrum Disorder, Earthquake, Behavior Problem of Childhood and Adolescence
- Trial name
- NCT05998382
- Testing
- Online group-based parent-mediated intervention program
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sabri Hergüner
Unspecified Behavioral and Emotional Disorders With Onset Usually Occurring in Childhood and Adolescence, Mental Disorder First Evident in Infancy, Childhood, or Adolescence
Assessing Implementation of Delivering Community-based, Peer-led Interventions for Mental Health Problems Among Youth in Eldoret, Kenya
Introduction: Mental health disorders are a leading cause of disability among youth globally, and this has been worsened by the COVID-19 pandemic.
- Conditions
- Unspecified Behavioral and Emotional Disorders With Onset Usually Occurring in Childhood and Adolescence, Mental Disorder First Evident in Infancy, Childhood, or Adolescence, Mental Disorder of Infancy, Childhood, or Adolescence (Diagnosis)
- Trial name
- Husisha (NCT06132373)
- Testing
- Peer delivered problem solving therapy
- Where
- Kenya
- Volunteers
- 182 people
- Sponsor
- Indiana University
Disruptive Behavior
Empowering Youth With School Discipline Referrals as Peer Coaches
The study will examine the effects of Peer Coach Training (PCT), a strengths-based behavioral intervention for discipline-referred middle-school youth who might benefit when trained to act as change agents for their peers.
- Trial name
- NCT07515742
- Testing
- Peer Coach Training (PCT), Delayed control
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Southern California
Autism Spectrum Disorder
Effect of ESDM and PCIT-A in Autism Spectrum Disorder
Children with ASD often show disruptive behaviors. However, interventions that were specifically designed to improve these symptoms have not been sufficiently investigated, especially in children with level 1 to level 3 ASD.
- Trial name
- TAFF (NCT04722783)
- Testing
- Parent-Child-Interaction Therapy adapted for children with autism spectrum disorder (PCIT-A), Early Start Denver Model (ESDM) intervention, 1-hour ESDM
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Bruno Rhiner
Epilepsy, Cysticercosis
Randomized Study of Albendazole in Patients With Epilepsy Due to Neurocysticercosis
OBJECTIVES: I. Determine the effect of antiparasitic treatment with albendazole on the severity and duration of epilepsy due to neurocysticercosis. II.
- Trial name
- NCT00004403
- Testing
- albendazole, dexamethasone, phenytoin
- Volunteers
- 120 people
- Sponsor
- Johns Hopkins University
Chronic Illness
Structuring the Integration of Care Management Services For Medicaid Enrollees Recipients With Chronic Illness, Substance Abuse Problems and Possible Psychiatric Disorders
The study seeks to measure the effect of increased coordination of care on medical costs, treatment utilization and selected clinical indicators among a Medicaid population with chronic medical conditions and substance abuse…
- Trial name
- NCT00399373
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Johns Hopkins University
Refractory Epilepsy
Modulation of Emotion Perception in Humans Via Amygdala Stimulation
This study will enroll patients with epilepsy who are being evaluated for epilepsy surgery and have intracranial EEG electrodes.
- Trial name
- NCT05292183
- Testing
- Electrical Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Affective Symptoms, Empathy
Facial Affect Sensitivity Training for Young Children With Callous-unemotional Traits
The goal of this study is to test a novel intervention for children ages 6-11 with elevated callous-unemotional (CU) traits. Conduct problems are among the most prevalent and costly mental health conditions of childhood, and a…
- Trial name
- NCT04159168
- Testing
- Facial Affect Sensitivity Training (FAST), Implicit Gaze Training task (Active control condition)
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- University of Alabama, Tuscaloosa
Child Behavior, Child Development
A Pilot Study of Teacher-Child Interaction Training - Universal in Head Start
This pilot study aims to implement and evaluate Teacher-Child Interaction Training - Universal (TCIT-U), an empirically-supported classroom-based intervention aimed at improving child behavior and social-emotional skills through…
- Conditions
- Child Behavior, Child Development, Child Behavior Problem
- Trial name
- TCIT-U (NCT04075071)
- Testing
- Teacher-Child Interaction Training - Universal
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Antisocial, Aggressive
Effect of Omega-3 Supplementation on Child Behavior Problems
The primary purpose of this study was to assess the effectiveness of omega-3 supplementation on behavior problems in children.
- Conditions
- Antisocial, Aggressive, Externalizing Behavior Problems, Internalizing Behavior Problems
- Trial name
- NCT02016079
- Testing
- omega-3
- Where
- Mauritius
- Volunteers
- 200 people
- Sponsor
- Joint Child Health Project, Mauritius
Substance Abuse, Mental Health
Optimizing a Drug Abuse Prevention Program for Dissemination
This project is a hybrid efficacy/effectiveness trial of a streamlined version of the Bridges program, an evidence-based intervention (EBI) to prevent substance abuse and mental health disorders.
- Conditions
- Substance Abuse, Mental Health, Educational Problems
- Trial name
- Bridges (NCT03125291)
- Testing
- Bridges 4-week Program
- Where
- United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Autoimmune Diseases, Mental Disorders Diagnosed in Childhood
Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)
Recent research studies of early onset-obsessive compulsive disorder (OCD) and Tourette's syndrome have questioned whether autoimmunity could play a role in the development of these conditions.
- Conditions
- Autoimmune Diseases, Mental Disorders Diagnosed in Childhood, Schizophrenia
- Trial name
- NCT00001768
- Testing
- Intravenous immunoglobulin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Mental Health (NIMH)
Pediatric Disruptive Behaviour Disorder
Strongest Families (Formerly Family Help Program): Pediatric Disruptive Behaviour Disorder
The purpose of the Strongest Families (formerly Family Help Program)is to evaluate the effectiveness of the Strongest Families distance intervention compared to usual or standard care that is typically provided to children with…
- Trial name
- NCT00267579
- Testing
- Strongest Families (formerly Family Help Program): Behaviour Disorder Program
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Mental Health, Public Health
The Effects of Yoga on Student Mental Health
The investigators performed a randomised controlled trial with 202 healthy university students in the Oslo area, with 50:50 in a yoga intervention group and a waitlist control group.
- Conditions
- Mental Health, Public Health, Depression, Anxiety, Sleep Problem
- Trial name
- NCT04258540
- Testing
- Yoga group, yoga course
- Where
- Norway
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Behavior Problems, Neurodevelopmental Disorders
RCT of PR-ESSENCE - a Problem Solving Model for Youth With Challenging Behavior in Special (SiS) Treatment Homes
Randomized controlled trial of PR-ESSENCE treatment for youth with challenging behavior in two youth treatment homes, including 60-70 youth.
- Trial name
- NCT04505072
- Testing
- PR-ESSENCE, Treatment as usual
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Göteborg University
Homeless Persons, Wound and Injuries
The WARM Study is a Pilot Study That Aims to Investigate the Impact of Environmental Factors on Acute and Chronic Wounds, Mental Illness, and Social Factors Among People Experiencing Housing Emergencies in Augsburg.
Providing healthcare to homeless people is a key and challenging task, both for society as a whole and for medical and psychosocial professionals.
- Conditions
- Homeless Persons, Wound and Injuries, Chronic Wound Care, Homelessness
- Trial name
- WARM (NCT07640672)
- Testing
- Wound care at the University Hospital and in the Johanniter mobile wound care unit
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Augsburg
Post-Traumatic Stress Disorder (PTSD)
Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD
Leveraging veterans' intimate relationships during treatment for posttraumatic stress disorder (PTSD) has the potential to concurrently improve PTSD symptoms and relationship quality.
- Trial name
- CBCT-OT RCT (NCT06194851)
- Testing
- Oxytocin nasal spray, Saline nasal spray, Brief Cognitive-Behavioral Conjoint Therapy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development