Clinical trials: Behavior
Caregiver Burden, Financial Stress
CONFIDENCE Financial Education for Caregivers
The purpose of this study is to determine how feasible it is to deliver an online course to reduce out-of-pocket costs of caregiving and reduce financial stress among Latino family caregivers to a family member living with…
- Conditions
- Caregiver Burden, Financial Stress, Dementia, Alzheimer Disease
- Trial name
- CONFIDENCE (NCT05292248)
- Testing
- Confidently Navigating Financial Decisions and Enhancing Financial Wellbeing in Dementia Caregiving
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Cardiac Failure, Heart Failure
Insomnia Self-Management in Heart Failure
Chronic insomnia may contribute to the development and exacerbation of heart failure (HF), incident mortality and contributes to common and disabling symptoms (fatigue, dyspnea, anxiety, depression, excessive daytime sleepiness…
- Conditions
- Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive
- Trial name
- HSS (NCT02660385)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Yale University
Infant, Extremely Low Birth Weight, Feeding Behavior
Somatosensory Modulation of Salivary Gene Expression and Oral Feeding in Preterm Infants
Two innovative approaches, pulsatile orocutaneous entrainment of non-nutritive suck via orosensory entrainment (NTrainer) device technology and serial salivary gene expression analyses, will be merged to examine the relation…
- Trial name
- NCT02696343
- Testing
- NTrainer
- Where
- 4 sites in United States
- Volunteers
- 121 people
- Sponsor
- University of Nebraska Lincoln
Cannabis, Cannabis Use
Marijuana Effects on Simulated Driving Performance
This study will examine the effects of various strains of marijuana on simulated driving performance; the effects of alcohol administration will also be examined to further understand how marijuana-induced driving changes compare…
- Conditions
- Cannabis, Cannabis Use, Marijuana, Marijuana Usage
- Trial name
- NCT03699540
- Testing
- Marijuana, Alcohol, Inactive marijuana
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Shanna Babalonis, PhD
Quality of Life, Brain Diseases
Long Term Survivors of High-grade Glioma and Their Caregivers
This study builds on the limited body of existing literature combined with the results from the investigators' previous research conducted with 30 newly diagnosed patients with high-grade glioma (HGG) and 33 of their caregivers.
- Conditions
- Quality of Life, Brain Diseases, Depression, Physical Impairment
- Trial name
- NCT02965144
- Testing
- no treatment
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Urticaria
Pilot Phase III Clinical Trial of JDP-205 IV Injection for Treatment of Acute Urticaria
This is a multicenter, parallel group, randomized, double-blind pilot Phase III clinical study of JDP-205 (cetirizine) injection, versus diphenhydramine injection, 50 mg/mL (Benadryl or generic equivalent), in approximately 36…
- Trial name
- NCT02023164
- Testing
- JDP-205 Injection, Diphenhydramine
- Where
- 6 sites in United States, Canada
- Volunteers
- 36 people
- Sponsor
- JDP Therapeutics, Inc.
Childhood Obesity
Translational Investigation of Growth and Everyday Routines in Kids
The purpose of this study is to determine the effect of severe obesity on physical activity, sedentary behavior and cardiometabolic risk factors during childhood and adolescence and whether these associations are modified by…
- Trial name
- TIGER Kids (NCT02784509)
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Attenuated Psychosis Syndrome
Exercise and Markers of Medial Temporal Health in Youth At-risk for Psychosis
The goal of this proposal is to test the feasibility and effectiveness of cardiovascular exercise in promoting brain health and improving related symptoms (e.g., hearing sounds that are not there, feeling emotionally detached…
- Trial name
- NCT02155699
- Testing
- Exercise 1, Exercise 2
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Premenstrual Syndrome, PMS
Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives
This study will determine whether uninterrupted treatment with birth control pills over several menstrual cycles prevents severe premenstrual syndrome (PMDD).
- Conditions
- Premenstrual Syndrome, PMS, Premenstrual Dysphoric Disorder, PMDD
- Trial name
- NCT00089414
- Testing
- Ethinyl Estradiol/Drospirenone, CDB 2914
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Mental Health (NIMH)
Lymphedema
Effect of Exercise on Indocyanine Green (ICG) Lymphography Imaging
Indocyanine Green (ICG) lymphography is a relatively new imaging technique that allows for quick visualization of superficial lymph flow in real-time, without radiation exposure.
- Trial name
- NCT03584633
- Testing
- Indocyanine Green
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Iowa
Alcohol Use Disorder
Zonisamide Treatment of Alcohol Use Disorder: an Evaluation of Efficacy and Mechanism of Action
This is a randomized, placebo-controlled, double-blind, 16 week trial of the medication zonisamide for the treatment of heavy drinking alcoholic civilians.
- Trial name
- Z-Comp (NCT02900352)
- Testing
- Zonisamide
- Where
- 4 sites in United States
- Volunteers
- 156 people
- Sponsor
- Virginia Commonwealth University
Cancer, Pediatric Cancer
Education Tools to Support Pediatric Survivor Care
This study aims to evaluate the impact of electronic educational materials on adolescent and young adult (AYA) survivors' knowledge about late effects, perceived benefits, self-efficacy, and intentions to engage in lifelong…
- Trial name
- NCT04257058
- Testing
- Electronic educational material
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Emory University
Smoking
Cessation in Non-Daily Smokers
The purpose of this study is to examine the effect of as-needed oral Nicotine Replacement Therapy (NRT) - 2 mg nicotine gum - for smoking cessation in non-daily, or intermittent, smokers, and to study the process of relapse in…
- Trial name
- QUITS (NCT02168855)
- Testing
- active nicotine gum, Standard behavioral therapy
- Where
- United States
- Volunteers
- 505 people
- Sponsor
- Brian Primack
Cardiovascular Risk Factor, Stress
Stress-reduction Wellness Program for Midlife Black Women (B-SWELL)
This research study examines the unique cultural and gender-based factors that influence how midlife Black women experience stress and incorporate healthy lifestyle behaviors into daily life.
- Conditions
- Cardiovascular Risk Factor, Stress, Self Efficacy, Depressive Symptoms
- Trial name
- B-SWELL (NCT04404478)
- Testing
- B-SWELL: Midlife Black Women's Stress Reduction Wellness Program, WE: Wellness program for Midlife Black Women
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Diabetes Mellitus, Physical Activity
Community-Clinic Partnership to Promote Physical Activity in South Asian Women
The goal of this study is to pilot-test a culturally-salient physical activity intervention, using a randomized design, among under served, overweight/obese South Asian women at high risk for developing Diabetes.
- Trial name
- NCT02342535
- Testing
- Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- Northwestern University
Chronic Low Back Pain, Negative Affectivity
Treating Negative Affect in Low Back Pain Patients
This study will examine how the use of antidepressant, physical therapy, and combination of both affects pain, function, and depression outcomes in chronic low back pain patients.
- Trial name
- TNA-LBP (NCT04747314)
- Testing
- Antidepressant, Enhanced Fear Avoidance Rehabilitation
- Where
- 3 sites in United States
- Volunteers
- 308 people
- Sponsor
- Ajay Wasan, MD, Msc
Sedentary Behavior, Exercise
Multiphase Optimization Trial of Incentives for Veterans to Encourage Walking
Regular physical activity (PA) is essential to healthy aging. Unfortunately, only 5% of US adults meet guideline of 150 minutes of moderate exercise; Veterans and non-Veterans have similar levels of PA.
- Conditions
- Sedentary Behavior, Exercise, Walking, Motivation
- Trial name
- NCT04518943
- Testing
- Walking
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- VA Office of Research and Development
Cerebral Palsy, Hemiplegia
Intensive Unimanual (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegia
A randomized control trial examining the relationship between changes in hand function and brain plasticity following intensive therapy.
- Conditions
- Cerebral Palsy, Hemiplegia, Children
- Trial name
- NCT02918890
- Testing
- Constraint-induced Movement Therapy, Hand-arm Bimanual Intensive Therapy
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Teachers College, Columbia University
LGBTQ
Assessing Mental Health Providers' Clinical Knowledge and Skills Via an Online Training on LGBTQ-affirmative Cognitive-behavioral Therapy
The purpose of the proposed study is to train mental health providers (MHPs) at lesbian, gay, bisexual, transgender, and queer (LGBTQ) community centers across the United States in evidence-based, LGBTQ-affirmative…
- Trial name
- NCT04559698
- Testing
- LGBTQ-affirmative CBT training
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity
Dopamine and Insulin Resistance
Obese individuals have fewer striatal dopamine type 2 receptors (DRD2) than normal weight individuals. Lower DRD2 levels are associated with addiction and a decreased sense of pleasure.Obesity is also associated with insulin…
- Trial name
- NCT00802204
- Testing
- PET scan, Oral glucose tolerance test, MRI
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University