Clinical trials: Bed Rest
Chronic Insomnia
Effects of Sleep Restriction and Stimulus Control in Chronic Insomnia Patients
The study aims to validate the effect of sleep restriction and stimulus control on improving chronic insomnia patients\' sleep habits and maladaptive sleep behaviors.
- Trial name
- NCT06658184
- Testing
- sleep restriction and stimulus control, sleep hygiene education
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xuanwu Hospital, Beijing
Glucose Intolerance
A Low Glycemic Index Diet for Prevention of Glucose Intolerance During Bed Rest
Recovery from surgery, injury or illness might require periods of bed rest in-hospital or at home. Bed rest may be needed for recovery but also has negative consequences.
- Trial name
- NCT03595943
- Testing
- Low glycemic index, pulse-based diet, Moderate glycemic index hospital diet
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Bone Diseases, Metabolic, Acid-Base Imbalance
The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation
Mainly due to the absence of gravitational forces in weightlessness, astronauts suffer from an increased bone loss- negatively affecting health and vitality during a mission.
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- NUC (NCT01509456)
- Testing
- Potassium Bicarbonate
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Bone Diseases, Metabolic, Acid-Base Imbalance
Short Term Bed Rest Study: Evaluation of the Use of Artificial Gravity, Induced by Short-arm Centrifugation
Randomized cross-over design with 10 male subjects and 3 campaigns to test whether the negative effects of bed rest (6º head-down tilt) on the various systems of the body and the consequences to health of simulated weightlessness…
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- SAG (NCT01820702)
- Testing
- Defined Training Programme
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Metabolic Syndrome, Type 2 Diabetes
Bed Rest, Alternate Daily Fasting and Incretin Effect
Bed rest produces insulin resistance in healthy volunteers. In this study the investigators aim to investigate the effect of 8 days bed rest on the incretin effect and how alternate daily fasting affects cognitive function and…
- Conditions
- Metabolic Syndrome, Type 2 Diabetes, Critical Illness
- Trial name
- NCT02134860
- Testing
- Bed rest, OGTT, IVGTT
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Bed Rest
Preserving Muscle Mass and Function in Bedridden Older Adults
The investigators propose that low-intensity exercise and supplementing daily meals with leucine or whey will independently and synergistically reduce the deleterious effects of inactivity on skeletal muscle and facilitate…
- Trial name
- EBR (NCT01846130)
- Testing
- Leucine, Exercise, Whey protein
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Bed Rest, Space Analogue
Impact of Energy Density on Energy Intake During Bed Rest
Brief summary: This study is conducted in the context of a 60 days strict bed-rest study with 6° head-down-tilt (HDT) body position.
- Trial name
- ED-REST (NCT06571877)
- Testing
- Dietary intervention with manipulation of the energy density
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Vascular Access Complication, Comfort
Immediate Mobilization After Cardiac Catheterisation
The purpose of this study is to investigate the frequency of bleeding and haematomas in patients undergoing coronary angiography or percutaneous coronary intervention via femoral artery and mobilized immediately after the…
- Trial name
- SAMOVAR (NCT02069275)
- Testing
- Immediate mobilization, Two hours bedrest
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Infectious; Spondylitis
Prolonged Bed Rest Versus Early Raising in Vertebral Osteomyelitis
Infectious vertebral osteomyelitis are infectious diseases of the vertebral bone, intervertebral disc and/ or adjacent tissue. Most of cases are due to hematogenous dissemination of pathogen but direct inoculation is an aetiology…
- Trial name
- SPONDYL'UP (NCT04735081)
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Muscle Atrophy, Insulin Sensitivity
Metabolic and Muscular Adaptations During Inactivity in 3 Days of Bed-rest
Space flight is associated with detrimental changes to the human body, including bone and muscle loss, fluid changes and deconditioning of muscles in the heart and blood vessels.
- Trial name
- NCT03495128
- Testing
- Bed Rest, Reconditioning
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Coronary Artery Disease With Myocardial Infarction
Clinical Trial to Assess the Safety of Reducing the Time of Bed Rest After Cardiac Catheterization
Reducing the rest time after diagnostic cardiac catheterization for three hours does not increase the complications concerning to the procedure, compared to the rest of five hours.
- Trial name
- Three-Cath (NCT01740856)
- Testing
- Rest three hours, Rest five hours
- Where
- Brazil
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Spinal Cord Injury
Mechanisms of Orthostatic Intolerance in Spinal Cord Injured Individuals and Following Bed Rest
The primary purpose of this study is to investigate the relationship between the extent of neurologic (nerve) impairment in patients with spinal cord injuries and how well the nerves passing down the spine to the heart and blood…
- Trial name
- NCT00175773
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Muscle Protein Synthesis, Muscle Atrophy
Exogenous Ketosis During Bed Rest in Older Adults
The goal of this randomized, double-blind, parallel group interventional study is to evaluate the effect of ketone bodies on healthy older adults (65-85 y) during 5 days of bed rest.
- Conditions
- Muscle Protein Synthesis, Muscle Atrophy, Insulin Sensitivity, Mitochondrial Function
- Trial name
- KBR (NCT05679596)
- Testing
- ketone monoester (R)-3-hydroxybutyl (R)-3- hydroxybutyrate
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University
Motility Disorder, Catabolic State
Gastro-intestinal and Hormonal Responses to Systemic Inflammatory Disease
The aim of this study is to describe hormonal responses and changes of the gastrointestinal (GI) tract during healthy and catabolic inflammatory conditions.
- Conditions
- Motility Disorder, Catabolic State, Endotoxemia
- Trial name
- NCT04056286
- Testing
- Whey, 3-OHB/whey
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Ankle Injuries, Fracture
Rest Easy: Is Bed Rest Really Necessary After Surgical Repair of an Ankle Fracture?
After a patient has fractured an ankle that then requires surgery, the recommendation is to remain in bed, with the operated leg elevated on pillows for 48 hours.
- Trial name
- NCT00690651
- Testing
- Early mobilization, Standard mobilization
- Where
- Australia
- Volunteers
- 104 people
- Sponsor
- The Alfred
Cervical Shortening
Routine Activity and Preterm Delivery Risk in Women With a Short Cervix
The goal of this clinical trial is to evaluate the effect of routine activity versus rest on the risk of preterm delivery in pregnant women with a short cervix diagnosed between 24 and 34 weeks of gestation.
- Trial name
- NCT06884761
- Testing
- Maximal Rest
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Wolfson Medical Center
Type 2 Diabetes, Muscle Atrophy
The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults
The goal of this study is to determine the impact of pre-diabetes and type 2 diabetes on muscle atrophy during a period of bed rest and recovery of muscle mass, strength, and physical function following bed rest.
- Conditions
- Type 2 Diabetes, Muscle Atrophy, Aging, Sedentary Behavior
- Trial name
- REST (NCT03761446)
- Testing
- Bed rest
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Rest, Healthy
The Effect of Short-term Bed Rest on Cardiac Function Measured by Cardiac Magnetic Resonance Imaging
The primary objective of this study is to investigate the effect of short-term bed rest (4 hours) on heart function, measured by cardiac magnetic resonance (CMR), in healthy participants.
- Trial name
- MRtime (NCT06644872)
- Testing
- Bedrest
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
High-Risk Pregnancy
Effects of Two In-hospital Antepartum Interventions on Functional Ability and Quality of Life in Early Postpartum Women.
The current standard of care for pregnant women deemed to be high-risk often involves recommending varying levels of activity-restriction, up to and including hospitalization.
- Trial name
- NCT02239341
- Testing
- Music Intervention, Muscle Conditioning Intervention
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Western University, Canada
Muscle Loss, Disuse Atrophy
Preventing Bed-rest Induced Muscle Loss in the Elderly
Episodes of inactivity due to hospitalisation, as short as 5 days, are associated with rapid muscle and strength loss in the elderly.
- Conditions
- Muscle Loss, Disuse Atrophy, Protein Metabolism, Prehabilitation
- Trial name
- NCT04422665
- Testing
- Resistance exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Birmingham