Clinical trials: Bed Rest
Bed Rest, Space Analogue
Impact of Energy Density on Energy Intake During Bed Rest
Brief summary: This study is conducted in the context of a 60 days strict bed-rest study with 6° head-down-tilt (HDT) body position.
- Trial name
- ED-REST (NCT06571877)
- Testing
- Dietary intervention with manipulation of the energy density
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
High-Risk Pregnancy
Effects of Two In-hospital Antepartum Interventions on Functional Ability and Quality of Life in Early Postpartum Women.
The current standard of care for pregnant women deemed to be high-risk often involves recommending varying levels of activity-restriction, up to and including hospitalization.
- Trial name
- NCT02239341
- Testing
- Music Intervention, Muscle Conditioning Intervention
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Western University, Canada
Healthy, Body Weight
IC-BASAROTs: New Practice Method for More Accurate Bed-side Assessment of Individual Energy Expenditure
Assessment of resting energy expenditure (REE) by indirect calorimetry (IC) in 1400 healthy individuals for arithmetical transformation into an bedside tool to estimate energy requirements in dietary practice (BASAROTs).
- Conditions
- Healthy, Body Weight, Overweight, Thinness
- Trial name
- NCT02682537
- Where
- 6 sites in Germany
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences Neubrandenburg
Healthy
Influence of Bedrest and Hypocaloric Nutrition on Endothelium-Dependent Vasoreactivity
Aim of the study is to assess the impact of the factors ´bed rest´ and ´hypocaloric nutrition´ on endothelium-dependent vasoreactivity in healthy volunteers.
- Trial name
- NCT00175968
- Testing
- bed rest, hypocaloric nutrition
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Cancer Patient Confined in the Bed
Osteopathy Treatment for Cancer Pain Related to the Confinement to Bed
Staying confined in the bed is frequent at the end of life. The cancer patients can also experiment this situation, and consequences are painful, with pain increasing with the time.
- Trial name
- OSTEO (NCT03440957)
- Testing
- Osteopathic treatment
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Hospices Civils de Lyon
Infectious; Spondylitis
Prolonged Bed Rest Versus Early Raising in Vertebral Osteomyelitis
Infectious vertebral osteomyelitis are infectious diseases of the vertebral bone, intervertebral disc and/ or adjacent tissue. Most of cases are due to hematogenous dissemination of pathogen but direct inoculation is an aetiology…
- Trial name
- SPONDYL'UP (NCT04735081)
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Vascular Access Complication, Comfort
Immediate Mobilization After Cardiac Catheterisation
The purpose of this study is to investigate the frequency of bleeding and haematomas in patients undergoing coronary angiography or percutaneous coronary intervention via femoral artery and mobilized immediately after the…
- Trial name
- SAMOVAR (NCT02069275)
- Testing
- Immediate mobilization, Two hours bedrest
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy
Evaluation of an Oral Nutritional Supplement on Lean Body Mass in Healthy Older Subjects.
The study will evaluate the effects of oral nutritional supplements (ONS) on attenuating the lean body mass (LBM) loss that occurs after bed rest.
- Trial name
- NCT02090387
- Testing
- ONS without AN777, ONS containing AN777
- Where
- 3 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Chronic Insomnia
Effects of Sleep Restriction and Stimulus Control in Chronic Insomnia Patients
The study aims to validate the effect of sleep restriction and stimulus control on improving chronic insomnia patients\' sleep habits and maladaptive sleep behaviors.
- Trial name
- NCT06658184
- Testing
- sleep restriction and stimulus control, sleep hygiene education
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xuanwu Hospital, Beijing
Type 2 Diabetes, Insulin Resistance
The Effects of Two Days of Bedrest on Insulin Resistance in Type 2 Diabetics
The hypothesis of this study is that bed rest in diabetic patients will result in a deterioration of metabolic control (primarily glucose). Specific aims: 1.
- Trial name
- NCT00508599
- Testing
- Study 2 (48 hours of complete bed rest)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Disuse Atrophy
Bed-rest, Muscle Mass and Insulin Sensitivity
In the present study, the effects of 7 days of bed rest on muscle mass, muscle fiber characteristics and insulin sensitivity will be determined.
- Trial name
- NCT02109380
- Testing
- Bed rest
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Infertility, Female
Immediate Ambulation Versus Short-time Bed Rest in Sub-fertile Women Undergoing Embryo Transfer
Bed rest after embryo transfer (ET) has been clinically advised without robust scientific evidence. In investigators' unit, post ET instructions are given immediately after ET to sub-fertile women while lying in bed.
- Trial name
- NCT05148624
- Testing
- embryo transfer
- Where
- United Arab Emirates
- Volunteers
- 156 people
- Sponsor
- Dubai Fertility Center
Weightlessness, Weightlessness; Adverse Effect
A New Nutritional Countermeasure to Prevent the Deconditioning Induced by 60 Days of Antiorthostatic Bed Rest
The objective of this study is to investigate whether the cocktail of natural antioxidants XXS-2A-BR2 comprising vitamin E and coupled with omega-3 helps to prevent and / or reduce the deleterious effects induced by long term…
- Trial name
- LTBRCocktail (NCT03594799)
- Testing
- Bed Rest Control Group, Cocktail intervention
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre National d'Etudes Spatiales
Countermeasure Evaluation
Medium-term Bedrest Whey Protein (MEP)
The human being has shown that he can live and work in the space environment, but due to the lack of essential mechanical load on muscle and bone, the fluid-shift as well as alterations in the acid-base balance (mainly on account…
- Trial name
- MEP (NCT01655979)
- Testing
- Whey Protein + Potassium bicarbonate, Control
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Skull Base
Bed Rest Duration and Outcomes in Endoscopic Skull Base Reconstruction
This study is a randomized controlled trial conducted across multiple centers. Due to the anatomical and pathological complexity of endoscopic endonasal skull base surgery, the study scope was restricted to the midline anterior…
- Trial name
- BRO (NCT07465861)
- Testing
- non-bed-rest, 2-day bed-rest, 1-day bed-rest
- Volunteers
- 316 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Critical Illness, Muscle Weakness
Progressive Mobility Program and Technology to Improve the Level of Physical Activity and Functionality of ICU Patients
The purpose of this study is to verify if a protocol of early and progressive mobility which includes the use of technology is able to increase the level of physical activity and improve functionality and respiratory and muscular…
- Trial name
- NCT02889146
- Testing
- Conventional Physical Therapy, Early and progressive mobilization program, Respiratory therapy
- Where
- Brazil
- Volunteers
- 98 people
- Sponsor
- University of Sao Paulo General Hospital
Bed Rest, Pregnancy
Physical Activity in Bed Rest Hospitalized High-Risk Pregnant Women
This pilot study aims to evaluate the impact of a specifically designed exercise program for hospitalized high-risk pregnant individuals on bed rest.
- Conditions
- Bed Rest, Pregnancy, Pregnancy Complications
- Trial name
- BedRest (NCT06713083)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Montse Palacio
Healthy, Overweight
The Effect of Blood Volume Changes on the Glucose Tolerance
In this study the investigators would like to elaborate on the mechanisms that lead to a higher insulin sensitivity after exercise training and a lower insulin sensitivity after bedrest.
- Trial name
- BV-GT (NCT02612597)
- Testing
- Bedrest, Exercise Training
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carsten Lundby
Bedrest
Effect of Bedrest With and Without Exercise on the Heart
The purpose of this research sub-study is to determine the changes in heart function during the bedrest period using ultrasound and MRI. This topic is important for medical care of astronauts in space.
- Trial name
- NCT00598494
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Muscle Protein Synthesis, Muscle Atrophy
Exogenous Ketosis During Bed Rest in Older Adults
The goal of this randomized, double-blind, parallel group interventional study is to evaluate the effect of ketone bodies on healthy older adults (65-85 y) during 5 days of bed rest.
- Conditions
- Muscle Protein Synthesis, Muscle Atrophy, Insulin Sensitivity, Mitochondrial Function
- Trial name
- KBR (NCT05679596)
- Testing
- ketone monoester (R)-3-hydroxybutyl (R)-3- hydroxybutyrate
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University