Clinical trials: Bacteremia Sepsis
Bacteremia, Catheter-Related Infections
Evaluation of Bacteremia Epidemiology During the COVID Period in One French University Hospital
The main objective of this retrospective cohort is to evaluate the impact of the first epidemic wave during lockdown on bacteremia epidemiology in one French University Hospital.
- Trial name
- NCT05640349
- Testing
- Positive blood culture
- Where
- France
- Volunteers
- 4,200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Staphylococcus Aureus Bacteremia
Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia
The purpose of this study was to compare the efficacy and safety of ceftobiprole medocaril versus a comparator in the treatment of patients with complicated Staphylococcus aureus bacteremia (SAB).
- Trial name
- NCT03138733
- Testing
- Ceftobiprole medocaril, Daptomycin
- Where
- 60 sites in United States, Argentina and 15 more
- Volunteers
- 390 people
- Sponsor
- Basilea Pharmaceutica
Healthy Volunteers
Vorapaxar in the Human Endotoxemia Model
Vorapaxar is a recently approved protease activated receptor - 1 (PAR-1) inhibitor. Platelet inhibition may also exert positive results on coagulation activation and may beneficially influence the inflammatory response.
- Trial name
- NCT02875028
- Testing
- Vorapaxar, LPS
- Where
- Austria
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Infection, Heart; Surgery, Heart, Functional Disturbance as Result
Device for Bacteremia Prevention in Post Cardiac Surgical Intensive Care Unit Patients
Intravenous catheters are often placed in large (central) veins in critically ill patients to provide special medications or frequent blood sampling.
- Conditions
- Infection, Heart; Surgery, Heart, Functional Disturbance as Result, Bacteremia
- Trial name
- CHG-Lock™ (NCT03309137)
- Testing
- Chlorhexidine flush
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Alison Fox-Robichaud
Bacteremia
A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures
The aim of this study is to evaluate the efficacy of prophylactic dosage with amoxicillin (AMX), amoxicillin-clavulanate (AMX-CLV), and a combination of amoxicillin-clavulanate and a chlorhexidine mouthwash (AMX-CLV-CHX) in the…
- Trial name
- NCT02115776
- Testing
- Amoxicillin-Potassium Clavulanate, Amoxicillin, Chlorhexidine
- Where
- 2 sites in Spain
- Volunteers
- 266 people
- Sponsor
- University of Santiago de Compostela
Bacteremia and Sepsis, Toll-Like-Receptors (TLRs)
Bacteremia in Intensive Care Unit (ICU)
The presence of bacteremia and sepsis in percent of critically ill patients and none at all, associated with different expression and faction of Toll-Like-Receptors (TLRs.
- Trial name
- NCT00932243
- Where
- Greece
- Volunteers
- 300 people
- Sponsor
- University of Thessaly
Skin Diseases, Infectious
Safety and Efficacy of BAY1192631 in Japanese Patients With Methicillin-resistant Staphylococcus Aureus (MRSA) Infections
The aim of this study is to see the efficacy and safety of BAY1192631 in Japanese patients with methicillin-resistant staphylococcus aureus (MRSA) (skin and soft tissue infections (SSTI) and SSTI-related bacteremia).
- Trial name
- NCT01967225
- Testing
- Tedizolid Phosphate (Sivextro, BAY1192631), Linezolid
- Where
- 46 sites in Japan
- Volunteers
- 125 people
- Sponsor
- Bayer
Staphylococcus Aureus, Bacteremia
Comparison of Nephrotoxicity and Hospital Costs in Patients With Methicillin-Resistant Staphylococcus Aureus Bacteremia Who Received Vancomycin Versus Teicoplanin Therapy
Staphylococcus aureus, the most virulent of the many staphylococcal species, has been recognized as one of the most important and lethal human bacterial pathogens.
- Trial name
- NCT01352936
- Where
- Taiwan
- Volunteers
- 190 people
- Sponsor
- Taipei Medical University WanFang Hospital
Bacteremia, Neoplasms
Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia
Children with cancer need a long term tunnelled central venous catheter (TCVC) for the entire duration of their treatment. TCVCs are locked with heparin when not in use.
- Trial name
- NCT00735813
- Testing
- Taurolock, Heparin
- Where
- Denmark
- Volunteers
- 129 people
- Sponsor
- Aarhus University Hospital
Endotoxemia
Ticagrelor in Human Endotoxemia Response to Human Endotoxemia
Rationale: In patients suffering a myocardial infarction the P2Y12 receptor antagonists prasugrel and ticagrelor improve outcome and prognosis compared to clopidogrel.
- Trial name
- NCT02612480
- Testing
- ticagrelor, Clopidogrel, Acetylsalicylic acid lysinate
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Dietary Habits, Endotoxemia
Effect of Monosaccharides on Intestinal Barrier Function
The aim of the present study is to determine the effect of monosaccharides on intestinal barrier function in healthy subjects.
- Trial name
- ENDO-META (NCT03482284)
- Testing
- Dietary Intervention
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Ina Bergheim
Bacteremia
Multicenter Blood Culture Quality Improvement
False positive blood culture results due to specimen contamination with bacteria inhabiting patients' skin is a common problem in emergency departments (EDs) in the United States.
- Trial name
- NCT01413555
- Testing
- Blood Culture QI Program
- Where
- 2 sites in United States
- Volunteers
- 14,889 people
- Sponsor
- Vanderbilt University
Endothelial Dysfunction
The Association Between Food Timing and Composition on Gastrointestinal Injury, Stress Hormone and Gastrointestinal Complains.
The study aimed to check the influence of timing and composition of diet on markers of gut injury, endotoxemia and stress.
- Trial name
- NCT06403241
- Testing
- 2000 meter ergometer test
- Where
- Poland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Catheter Related Infections
Safety and Bacteraemia Between Peripherally Inserted and Central Inserted Catheters.
Clinical, prospective, single-center, national trial. open and randomized at 1: 1 to compare the rate of bacteremia associated between non-tunneled Central venous catheter and peripheral inserted central catheter.
- Trial name
- PYCBAC (NCT02538159)
- Testing
- CVC, PICC
- Where
- Spain
- Volunteers
- 247 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Gram-negative Bacteremia, Microbial Colonization
Antimicrobial Resistant Organism Decolonization After Microbiome Perturbation
ARO-DECAMP is a multi-centre, placebo-controlled, pilot and feasibility randomized controlled trial for the microbial consortium Microbial Ecosystem Therapeutic-2.
- Conditions
- Gram-negative Bacteremia, Microbial Colonization, Antibiotic Resistant Infection
- Trial name
- ARO-DECAMP (NCT06214403)
- Testing
- MET-2
- Where
- 4 sites in Canada
- Sponsor
- University Health Network, Toronto
Pneumonia, Bacterial
Study Evaluating Streptococcus Pneumoniae Serotype Carriage Rate for Nasopharyngeal Carriage in Filipino Children
Evaluation of the carriage rate of Streptococcus pneumoniae in the nasopharynx of healthy children and the carriage rate and distribution of Streptococcus pneumoniae serotypes
- Trial name
- NCT00724828
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Hypoxia, Endotoxemia
Cerebral Blood Flow and Metabolism During Hypoxia and Endotoxemia
The objective of the present protocol is to study whether a low level of oxygen in the blood will affect the immune response to as well as cerebral blood flow and metabolism during an infection and, conversely, whether the acute…
- Conditions
- Hypoxia, Endotoxemia, Healthy
- Trial name
- NCT00332267
- Testing
- Endotoxin infusion, Normobaric hypoxia
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet