Clinical trials: Back Pain, Low
Chronic Pain, Chronic Low-back Pain
Ultra Low Frequency Spinal Cord Stimulation for Chronic Low Back Pain
The Presidio Medical Ultra Low Frequency (ULF™) Spinal Cord Stimulation (SCS) System is intended to provide pain relief to participants who have been clinically diagnosed with chronic low back pain with or without leg pain.
- Trial name
- NCT05837234
- Testing
- ULF SCS
- Where
- 3 sites in Australia
- Volunteers
- 55 people
- Sponsor
- Presidio Medical, Inc
Back Pain
The Effectiveness of Manual Therapy and PNF Compared With Kinesiotherapy in the Treatment of Non-specific Low Back Pain
The aim of the study was to determine whether the use of combination therapy consisting of manual therapy and proprioceptive neuromuscular facilitation (PNF) is more effective than the use of the techniques of manual therapy, PNF…
- Trial name
- NCT03733964
- Testing
- Manual therapy, PNF, Manual therapy + PNF
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Lublin
Chronic Low Back Pain (Non-specific, Uncomplicated)
Evaluation of the Effectiveness and Safety of Mesotherapy in the Treatment of Chronic Low Back Pain Syndrome
The aim of this study is to evaluate the effectiveness of collagen mesotherapy in the treatment of chronic low back pain (CLBP) in the lumbosacral spine.
- Trial name
- NCT07675304
- Testing
- Tropocollagen type I, Lignocaine 1% concentration solution
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Chronic Low Back Pain, Self-Management
Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain
This pilot project will provide an understanding of the contextual variables responsible for chronic low back pain. These variables include, genetic variation, pain sensitivity, reactivity, pain catastrophizing, perceived stress…
- Trial name
- PROPEL (NCT03637998)
- Testing
- Problem-solving Pain to Enhance Living Well (PROPEL)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
Fibromyalgia (FM), Chronic Low Back Pain (CLBP)
Pain Neuroscience Education for Chronic Pain
Chronic pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, with a high prevalence in Spain (25.9%) and an average duration of 6.83 years, highlighting its significant health…
- Conditions
- Fibromyalgia (FM), Chronic Low Back Pain (CLBP), Chronic Pain
- Trial name
- PNE (NCT07693998)
- Testing
- Therapeutic Exercise and Education in Pain Neuroscience
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- University of Valencia
Chronic Pain, Low Back Pain
High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System
Study designed to compare the conventional stimulation programming versus the high frequency stimulation programming of the spinal cord stimulator for subjects who already have a spinal cord stimulator.
- Conditions
- Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
- Trial name
- HFSCS (NCT02265848)
- Testing
- High frequency stimulation, Low frequency stimulation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical Research, Winston-Salem, NC
Chronic Low-back Pain
The Effectiveness of Kinesio Taping in Patients With Chronic Low Back Pain
The objective of this study is to determine the effectiveness of Kinesio taping (KT) with Conventional Physical therapy (CPT) - Transcutaneous Electrical Nerve Stimulation (TENS) and Supervised Exercise therapy and CPT in the…
- Trial name
- NCT05173948
- Testing
- Kinesio taping, Conventional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- University of Tabuk
Gluteus Medius, Ultrasonography, NSCLBP
Gluteus Medius Strengthening n Non Specific Chronic Low Back Pain
To study the effect of adding selected G Med muscle strengthening exercises to the APTA-guided program on pain, disability level, and G Med macromorphology in patients with NSCLBP.
- Trial name
- NCT05521165
- Testing
- therapeutic exercises
- Volunteers
- 58 people
- Sponsor
- Cairo University
Low Back Pain, Manual Therapy
A Randomized Placebo Controlled Trial on the Efficacy of Sustained Natural Apophyseal Glide (SNAG) in Low Back Pain Patients
Objectives: Determine the efficacy of the SNAG technique (Mulligan) applied to a subgroup of people with non-specific low back pain (LBP) on two new kinematic-algorythms, on pain, functional disability and kinesiophobia.
- Conditions
- Low Back Pain, Manual Therapy, Sustained Natural Apophyseal Glide (SNAG)
- Trial name
- NCT02128607
- Testing
- SNAG
- Where
- Belgium
- Volunteers
- 32 people
- Sponsor
- Université Catholique de Louvain
Low Back Pain
Potential of Virtual Reality in Primary Chronic Low Back Pain
This is a single-case experimental design study enrolling individuals with chronic low back pain who will be receiving pain science education and virtual reality over 3 weeks.
- Trial name
- NCT07742111
- Testing
- Pain science education and virtual reality
- Where
- Portugal
- Volunteers
- 12 people
- Sponsor
- Aveiro University
Low Back Pain
The Effect of Exercise on Motion Perception and Fear in Low Back Pain
Nonspesific low back pain (NLBP), which negatively affects functionality, activity participation, and financial situation, is now one of the leading causes of disability in the world.
- Trial name
- NCT05433311
- Testing
- Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Chronic Low-back Pain (cLBP)
Virtual Reality Based High-intensity Interval Training in Chronic Low Back Pain
One of the most prevalent causes of pain on a global scale is chronic musculoskeletal pain. Low back pain is a prevalent manifestation of chronic musculoskeletal pain.
- Trial name
- NCT07388134
- Testing
- Virtual reality based high intensity interval training (VR-HIIT) group, High intensity interval training (HIIT) group
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Universidad de Granada
Chronic Low Back Pain, Opioid-induced Hyperalgesia
Opiate-Induced Tolerance & Hyperalgesia in Pain Patients
Opiates such as morphine are the cornerstone medications for the treatment of moderate to severe pain. Recent evidence suggests that pain patients on chronic opioid therapy become more sensitive to pain (hyperalgesia) over time.
- Trial name
- NCT00246532
- Testing
- Morphine
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Major Depressive Disorder, Back Pain
Duloxetine Treatment of Major Depression and Chronic Low Back Pain For Older Adults
The following primary hypotheses will be tested: 1. During Step 1: Major Depressive Disorder (MDD) or Chronic Low Back Pain (CLBP) in < 40% of the initial 60 subjects treated with duloxetine (DUL) + Clinical Management(CM) during…
- Conditions
- Major Depressive Disorder, Back Pain, Aged
- Trial name
- ACHIEVE2 (NCT00696293)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Peptic Ulcer
Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcers
The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
- Trial name
- NCT00450658
- Testing
- HZT-501, Ibuprofen
- Volunteers
- 627 people
- Sponsor
- Amgen
CRPS (Complex Regional Pain Syndromes), Radiculopathy
Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy
This study seeks to evaluate the use of intermittent dosing as an alternative paradigm for patients with DRG stimulation in place for at least 1 year and minimum 50% pain relief in the targeted area.
- Conditions
- CRPS (Complex Regional Pain Syndromes), Radiculopathy, Peripheral Neuropathy
- Trial name
- NCT04909138
- Testing
- DRG stimulation 20 Hz 30/90, DRG stimulation 5 Hz 30/90
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rush University Medical Center
Low Back Pain
Value of Manual Therapy Specificity Referred to Pain Intensity in Patients With Subacute and Unspecified Low Back Pain
This study proves the specificity of manual therapy in unspecified an subacute low back pain
- Trial name
- NCT04955314
- Testing
- PA vertebral mobilization
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- University of Jaén
Chronic Low Back Pain
Chronic Low Back Pain Graded - Exposure Psychoeducation Intervention
This study will examine the effectiveness of one of two psychoeducation treatments on chronic low back pain.
- Trial name
- VRGE (NCT03909048)
- Testing
- Interactive - Psychoeducation, Non-interactive Psychoeducation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Low Back Pain (LBP)
The Effect of Grinberg Method (GM) Intervention on Low-back Pain (LBP) and Improving the Quality of Life
The purpose of the research is to check the efficiency of practicing the tools of the Grinberg method (GM) in reducing Low-back Pain (LBP), reducing limitations in movement as a result of the pain, and improving the general…
- Trial name
- NCT01474447
- Testing
- Grinberg Method
- Where
- Israel
- Volunteers
- 140 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Low Back Pain
Effects of Hipopressive Exercises in Nonspecific Low Back Pain
Introduction Non-specific low back pain is very prevalent in our society. Different effective physiotherapy treatments have been performed in the reduction of pain and improvement of quality of life, however there are few studies…
- Trial name
- HPvsMT-LBP (NCT03565926)
- Testing
- Manual Therapy, Hypopressive exercises
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Valencia