Clinical trials: Back Pain, Low
Multi-Organ Disorder
Pulsed RF Neuromodulation and Leukocyte-Rich PRP for Refractory Low Back Pain
This clinical trial aims to check the safety and efficacy profile of pulsed radiofrequency (RF) neuromodulation combined with leukocyte-rich platelet-rich plasma (PRP) injections for the treatment of refractory low back pain due…
- Trial name
- Multifidus (NCT06524531)
- Testing
- Pulsed RF Neuromodulation, Leukocyte-Rich PRP Injection, Physiotherapy Alone
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Iffat Anwar Medical Complex
Low Back Pain
Randomised Controlled Trial for the selfBACK Project
The intervention consists of a digital decision support system delivering a weekly plan of suggested activities that the participant can use to self-manage their low back pain (LBP) via an smartphone app.
- Trial name
- selfBACK (NCT03798288)
- Testing
- selfBACK, Usual care
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 461 people
- Sponsor
- University of Southern Denmark
Low Back Pain, Recurrent
Evaluation of Performances and Safety of the Medical Device Blueback® Physio for Patients With Chronic Low Back Pain
The main objective of this clinical investigation is to show the superiority of a rehabilitation based on the use of Blueback® Physio compared to a rehabilitation without the use of Blueback® Physio in terms of reducing the time…
- Trial name
- ABC-TRACC (NCT04592094)
- Testing
- Blueback® Physio
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Blueback
Low Back Pain
Enhanced Implementation of Low Back Pain Guidelines in General Practice
The aim of this study is to evaluate whether an enhanced strategy of implementation of the new guideline will lower the number of patients getting referred to secondary care spine centres compared to a normal implementation…
- Trial name
- NCT01699256
- Testing
- Guideline implementation as usual, Enhanced guideline implementation strategy
- Where
- Denmark
- Volunteers
- 1,101 people
- Sponsor
- University of Aarhus
Chronic Pain, Low Back Pain
Cost-Effectiveness Analysis of a Virtual Reality-Assisted Hypnotherapy Program on Quality of Life in Patients with Chronic Low Back Pain: a Multicenter, Randomized, Prospective, Comparative, Open-Label, Parallel-Group Study
This randomized, prospective study aims to evaluate the effectiveness and cost-efficiency of a Virtual Reality (VR)-assisted hypnotherapy program on quality of life in patients with chronic low back pain.
- Conditions
- Chronic Pain, Low Back Pain, Chronic Low Back Pain (CLBP)
- Trial name
- NCT06698354
- Testing
- Virtual Reality-Assisted Hypnotherapy, Standard Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Beykent
Low Back Pain
Pilates Exercises on Pain, Fatigue, Endurance, and Muscle Strength in Non-Specific Low Back Pain
Pilates exercises administered under the supervision of a physiotherapist on pain, endurance, and muscle strength in individuals with non-specific low back pain, and to determine which program is more beneficial and reliable.
- Trial name
- NCT06943066
- Testing
- Reformer Pilates, Pilates control, online pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Low Back Pain
Manipulation Effects on Abdominal Muscles
The purpose of this study is to understand how different physical therapy interventions affect the use of certain abdominal muscles in patients with low back pain.
- Trial name
- NCT01745939
- Testing
- Lumbar Manipulation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Chronic Low Back Pain
Comparison of Senza to Commercial Spinal Cord Stimulation for the Treatment of Chronic Pain
The purpose of this investigational study is to establish the safety and effectiveness of electrical stimulation delivered to the spinal cord in subjects with chronic, intractable pain of the trunk and/or limbs and will be a…
- Trial name
- SENZA-RCT (NCT01609972)
- Testing
- Spinal Cord Stimulator
- Volunteers
- 356 people
- Sponsor
- Nevro Corp
Chronic Low Back Pain
Cognitive Interventions and Nutritional Supplementation for Patients With Long-lasting Back Pain
CINS is a large multicentre study which aims to test out the effect of 4 different interventions, namely a brief cognitive intervention (BI), a more extensive cognitive behavioural intervention (CBT), and 2 different nutritional…
- Trial name
- CINS (NCT00463970)
- Testing
- Brief Intervention, Cognitive Behavioural Therapy, Seal oil
- Where
- 2 sites in Norway
- Volunteers
- 414 people
- Sponsor
- NORCE Norwegian Research Centre AS
Low Back Pain
A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain
The primary objective is to assess the efficacy of oxycodone/naloxone controlled-release tablets (OXN) for the management of opioid-induced constipation (OIC) compared with oxycodone controlled-release tablets (OXY) in subjects…
- Trial name
- NCT01427283
- Testing
- Oxycodone/Naloxone controlled-release, Oxycodone HCl controlled-release
- Where
- 149 sites in United States
- Volunteers
- 450 people
- Sponsor
- Purdue Pharma LP
Motor Imagery
Telerehabilitation-based Motor Imagery in Nonspecific Low Back Pain
Low back pain is a common problem in society and causes loss of workforce. Its lifetime prevalence reaches 80% and annual hospital admission rates in the adult population reach 15%.Most studies on motor imagery suggested the…
- Trial name
- NCT05049772
- Testing
- Telerehabilitation-based motor imagery training, Stabilization exercises group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Low Back Pain
Special Lower Back Pillow Examination
Low back pain is a significant, serious and widespread problem in our world today, both in terms of social and economic burdens.
- Trial name
- LBP PILLOW (NCT05486845)
- Testing
- survey
- Where
- Hungary
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Szeged University
Chronic Low-back Pain, Lumbal Disc Herniation
The Effect of Mulligan Mobilization Technique on Balance, Pain and Functionality in Patients With Chronic Low Back Pain
This study was aimed to investigate the effectiveness of mulligan mobilization technique on balance, pain and functionality in patients with chronic low back pain and to compare it with exercise.37 patients aged between 18-65 who…
- Conditions
- Chronic Low-back Pain, Lumbal Disc Herniation, Imbalance
- Trial name
- NCT05334394
- Testing
- Mulligan Technique, Exercise Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Medipol University
Lower Back Pain, Pelvic Pain
Musculoskeletal and Obstetric Management Study
The investigators propose such a trial to compare a Musculoskeletal and Obstetric Management (MOM) program to standard obstetric care alone for lower back pain/pelvic pain (LBP/PP) during and after pregnancy.
- Conditions
- Lower Back Pain, Pelvic Pain, Musculoskeletal Pain
- Trial name
- MOMS (NCT00905112)
- Testing
- Manual Therapy, Standard OB Care
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- Logan College of Chiropractic
Chronic Low Back Pain, Sacroiliitis
Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint
This prospective study will be quantitatively analyzing the effectiveness of platelet-rich-plasma (PRP) injections into the sacroiliac (SI) joint in relieving sacroiliitis and low back pain originating from the SI joint.
- Conditions
- Chronic Low Back Pain, Sacroiliitis, Sacroiliac; Backache, Platelet Rich Plasma
- Trial name
- NCT03122119
- Testing
- Platelet Rich Plasma Joint Injection
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Star Spine and Sport
Chronic Low-back Pain (cLBP)
Acceptance and Commitment Therapy Plus Exercise for Older People With Chronic Low-back Pain: A Pragmatic Cluster Randomised Controlled Trial
Low back pain (LBP) is the fifth-most common disorder among older adults 60 years or older. The prevalence of LBP increases with age, with the highest prevalence occurring at 85 years old.
- Trial name
- NCT07211464
- Testing
- Acceptance and commitment therapy (ACT), back exercise, back care education
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
Degenerative Disc Disease, Discogenic Low Back Pain
A Comparative Study Between Mechanical and a Viscoelastic Disc Prosthesis in the Lumbar Spine
TDR implants for the lumbar spine are currently most 2- or 3-piece devices with a purely mechanical function that provide/restore mobility.
- Trial name
- NCT03716947
- Testing
- Device: ZACK, Device: ORBIT, Device: SASCA
- Where
- Sweden
- Volunteers
- 246 people
- Sponsor
- Karolinska Institutet
Intervertebral Disc Degeneration, Modic I Discopathy
Efficiency and Safety Study of Pamidronate in Inflammatory Back Pain Due to Degenerative Disk Disease
The purpose of this study is to determine whether pamidronate is effective and well-tolerated in the treatment of painful degenerative disk disease, also known as Modic type 1 changes
- Conditions
- Intervertebral Disc Degeneration, Modic I Discopathy, Back Pain, Low Back Pain
- Trial name
- NCT01799616
- Testing
- Pamidronate
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Clermont-Ferrand
Most Common Musculoskeletal Problems in Pregnancy
Musculoskeletal Problems During Pregnancy
Aim: This study was conducted to identify the most common musculoskeletal problems according to trimester, experienced by pregnant women.
- Trial name
- NCT04496206
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Eskisehir City Hospital
Non Specific Chronic Low Back Pain, Exercise Therapy
Effect of Video-based Stabilization Exercises on Pain, Function, Adherence, Kinesiophobia & QoL in NSCBP Patients
This randomized controlled study aims to evaluate the effectiveness of a 6-week home-based stabilization exercise program in individuals with non-specific chronic low back pain.
- Trial name
- NCT07005765
- Testing
- Video-Based Stabilization Exercise Program, Brochure-Based Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Serra Sürel