Clinical trials: BMI>40
Healthy
Interactions Between Fibre and Polyphenols on Colonic Phenolic Acid Production and Biomarkers of Health ( 6 Weeks)
The investigators have studied the acute interactions of polyphenols and NDC in a single meal in a human study containing tomatoes, lovage \& onions, with and without inulin.
- Trial name
- NCT03840746
- Testing
- Tomato, onion and lovage soup (TOL), TOL soup with inulin
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Obesity, Morbid, Labor Pain
LOTUS Trial: Lumbar Ultrasound in Obstetric Patients With BMI > 40
The goal of this clinical trial is to compare traditional palpation to pre-procedural lumbar ultrasound prior to epidural placement in obese (BMI >40) obstetric patient population.
- Trial name
- LOTUS (NCT06305260)
- Testing
- Lumbar Ultrasound
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Morbid Obesity
Follow-up of Adolescent Bariatric Surgery
Very little information is available about extremely obese (body mass index [BMI] > 40 kg/m2) adolescents. The purpose of the Follow up of Adolescent Bariatric Surgery (FABS) study is to collect information obtained during the…
- Trial name
- FABS (NCT00776776)
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Morbid Obesity
The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who…
- Trial name
- NCT05342922
- Testing
- Ultrasound group, Landmark group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Obesity, Wound Infection
Kerlix for Pregnant Women With Elevated BMI to Prevent Wound Infection by 6 Weeks Post Partum
Pregnant women with BMI>40 will be approached for participation in a study to reduce the rate of post-operative wound infection from C-section.
- Conditions
- Obesity, Wound Infection, Pregnancy
- Trial name
- NCT02882360
- Testing
- Kerlix-AMD
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obesity, Obesity, Morbid
Comparing Anti-XA Levels in Post-Cesarean Patients Undergoing Enoxaparin Thromboprophylaxis
Pregnant and recently postpartum women are at significantly higher risk of developing a blood clot in their arms or legs known as a deep venous thrombosis (DVT) and/or a blood clot in their lungs known as a pulmonary embolism…
- Conditions
- Obesity, Obesity, Morbid, Pregnancy, Complications; Cesarean Section
- Trial name
- NCT02070237
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
LMA Vs I Gel
Randomized Comparative Study Between Classic Laryngeal Mask Airway and I Gel Airway in Obese Patients Having BMI 35-40 During Elective Non Abdominal Surgery.
Invistigators study both supraglottic airway devices; the classic LMA and the I GEL mask are satisfactory devices providing high airway leaking pressures.
- Trial name
- NCT03843827
- Testing
- Laryngeal Mask Airway, I gel Airway
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Surgical Site Infections
Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery
The investigators aim to show that single use negative pressure dressings can decrease the rate of wound complications in obese women (BMI > 40 kg/m2) undergoing cesarean delivery at a tertiary medical center by randomizing women…
- Conditions
- Obesity, Surgical Site Infections, Wound Complications, Complications; Cesarean Section
- Trial name
- NCT02799667
- Testing
- Standard Dressing, Negative Pressure Wound Therapy Dressing
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Endometrial Cancer
A Randomized, Controlled, Comparative Study of a Levonorgestrel Intrauterine System for the Prevention of Endometrial Cancer in Patients Aged 40-50 With BMI Greater Than 35
Endometrial (uterine) cancer affects over 40,000 women each year in the United States. At this time there are no medications to prevent endometrial cancer. Women who are heavy are at increased risk of this cancer.
- Trial name
- NCT00161226
- Testing
- Levonorgestrel intrauterine system
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Dentistry of New Jersey
Cesarean Wound Disruption With Postnatal Complication
Comparative Analysis of Subcuticular Suture Materials in Cesarean Section
1.1. Background and Rationale Cesarean section is one of the most common surgical procedures performed worldwide. The choice of suture material for closing the skin incision is crucial, as it can influence wound healing, the risk…
- Trial name
- NCT06543329
- Testing
- polyglactin 910, poliglecaprone 25, polypropylene
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cairo University
Apnea, Obstructive Sleep, Obesity
Association of Body Fluid Distribution With Obstructive Sleep Apnea in Pregnant Women With Body Mass Index ≥ 40 kg/m2
Obstructive Sleep apnea (OSA) is a common and underdiagnosed condition in obese pregnant women with serious and life-threatening complications to the mother and baby.
- Trial name
- NCT04187612
- Testing
- Bioelectrical Impedance Analysis (BIA)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Overweight
Orlistat Induced Modulation on the Fatty Acid Composition in Obese Females
Orlistat is a popular drug approved for long-term use which produces weight loss by inhibiting triglycerides, main components of fats in the diet and reducing dietary fat absorption by up to 30%.
- Trial name
- NCT01414465
- Testing
- Orlistat
- Where
- Brazil
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
BMI>40
Evaluating Metabolic Health in Individuals With Extreme Obesity
This research will evaluate energy metabolism (expenditure and fat oxidation), metabolic flexibility (response to a high-fat test meal) in 10 individuals with a BMI ≥60 kgm2 using gold-standard assessments of energy metabolism…
- Trial name
- NCT07613255
- Testing
- High-fat test meal
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Healthy
A Study to Test How Different Doses of BI 456906 Are Tolerated in Japanese Men With a Body Mass Index (BMI) Between 23 and 40 kg/m2
Main objectives are to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of different dose escalation schemes of BI 456906 in healthy Japanese male subject with BMI 23-40 kg/m2 and to determine a dose…
- Trial name
- NCT04384081
- Testing
- BI 456906
- Where
- Japan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Obesity, Infection; Cesarean Section
Skin Incisions and Wound Complication Rates for C-sections in Obese Women
It is the purpose of this study to evaluate the relationship between a low transverse, vertical midline, and supra-panicular high transverse skin incisions and the rate of wound complications in women with a BMI of 40 or greater…
- Conditions
- Obesity, Infection; Cesarean Section, Surgical Wound
- Trial name
- NCT02685761
- Testing
- Midline Vertical, High Transverse
- Where
- 7 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Overweight or Obesity
Pylorus Distensibility Measurement
The present study aims at characterizing the pylorus functionality in overweight and obese patients (BMI 27-40) using a systematic measurement approach by using an impedance planimetry technology.
- Trial name
- NCT06908551
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- BariaTek Medical
Obesity
Study of Low Level Laser Therapy to Reduce Body Circumference in Obese Individuals
The purpose of this study is to determine whether low level laser light therapy is effective in reducing circumference of the waist, hips and upper abdomen in obese individuals.
- Trial name
- NCT01821352
- Testing
- Erchonia Obesity Laser
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation