Clinical trials: Azithromycin
Child Development
Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso
The use of antibiotics has saved millions of human lives, however consumption of antibiotics can select for antibiotic resistant organisms and may lead to changes in commensal microbiome.
- Trial name
- ARMCA (NCT03187834)
- Testing
- Azithromycin, Amoxicillin, Cotrimoxazole
- Where
- 2 sites in United States, Burkina Faso
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Comparative Effects of Azithromycin, Telithromycin and Levofloxacin on Drug Metabolizing Enzymes
Studies have previously shown that a broad drug interaction screening can be performed using enzyme specific probes such as oral caffeine for CYP1A2, N-acetyltrasferase-2 (NAT-2), and xanthine oxidase (XO), warfarin plus vitamin…
- Trial name
- NCT00164112
- Testing
- Cooperstown 5+1 alone, Azithromycin plus Cooperstown 5+1, Telithromycin plus Cooperstown 5+1
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bassett Healthcare
COVID-19
Evaluate the Efficacy and Safety of Oral Hydroxychloroquine, Indomethacin and Zithromax in Subjects With Mild Symptoms of COVID-19
Currently there are no US Food and Drug Administration (FDA)-approved drugs specifically for the treatment of patients with COVID-19.
- Trial name
- COVID-19 (NCT04344457)
- Testing
- Hydroxychloroquine, Indomethacin, Zithromax Oral Product
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Perseverance Research Center, LLC
Chronic Rhinosinusitis, High-risk Patient
Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapy
Justification: Chronic rhinosinusitis (CRS) is one of the most common inflammatory diseases with an incidence and prevalence superior to 10%.
- Trial name
- AZI-CRS (NCT02307825)
- Testing
- Azithromycin
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Chlamydial Conjunctivitis
The Effect of Oral Azithromycin in the Treatment of Chlamydial Conjunctivitis
Chlamydia trachomatis is one of the major causes of sexually transmitted disease and also the leading infectious cause of blindness in the world.Treatment of C. trachomatis eye infection has involved for a long time.
- Trial name
- NCT01178762
- Testing
- Azithromycin
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- National Taiwan University Hospital
Meningococcal Infections
Azithromycin for Meningococcal Carriage
The purpose of this study is to determine the effectiveness of azithromycin in the eradication of nasopharyngeal carriage of N. meningitidis
- Trial name
- NCT06618534
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- Emory University
COVID-19
Azithromycin in Hospitalized COVID-19 Patients
The present study is a randomized, double-blind, controlled, clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Shahid Modarres Medical…
- Trial name
- AIC (NCT04359316)
- Testing
- Hydroxychloroquine, Azithromycin
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Yaws, Treponema Infection
Single-dose Azithromycin for the Treatment of Yaws
Yaws, an endemic treponematosis and as such a neglected tropical disease (NTD), is currently making a comeback in children in rural areas. Injectable long acting penicillin remains the drug of choice for the treatment of yaws.
- Conditions
- Yaws, Treponema Infection, Neglected Tropical Disease
- Trial name
- NCT01382004
- Testing
- Penicillin-G-benzathine, Azithromycin
- Where
- Papua New Guinea
- Volunteers
- 255 people
- Sponsor
- Lihir Medical Centre
Bronchopulmonary Dysplasia
TINN2: Treat Infection in NeoNates 2
The aim of the TINN2 study is to evaluate the efficacy of azithromycin in prevention of bronchopulmonary dysplasia in preterm neonates.
- Trial name
- TINN2 (NCT02282176)
- Testing
- Azithromycin
- Where
- 16 sites in Belgium, France and 7 more
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Lymphatic Filariasis, Yaws
PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs )
This is a Pharmacokinetic and Pharmacodynamic study evaluating the safety of co-administering Azithromycin alongside the new IDA (Ivermectin, Diethylcarbamazine, Albendazole) combination treatment for LF.
- Conditions
- Lymphatic Filariasis, Yaws, Trauma
- Trial name
- NCT03664063
- Testing
- Azithromycin, Albendazole, Ivermectin
- Where
- Papua New Guinea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lihir Medical Centre
Periodontitis
Efficacy of Azithromycin as an Adjunct to Non-Surgical Periodontal Treatment
This study evaluates the effect of the systemic administration of azithromycin as a therapy associated with non-surgical periodontal treatment, in the clinical and microbiological variables of patients with Severe Periodontitis…
- Trial name
- NCT03629288
- Testing
- Lactose tab, Azithromycin
- Where
- Chile
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Andres Bello
Pneumonia, Community-Acquired
A Trial Of Azithromycin SR For The Treatment Of Mild To Moderate Community Acquired Pneumonia In Japanese Adults
To evaluate the clinical efficacy and safety in patients with mild or moderate community-acquired pneumonia receiving a dose of 2 g of azithromycin in the SR formulation.
- Trial name
- NCT00360295
- Testing
- Azithromycin SR
- Where
- 54 sites in Japan
- Volunteers
- 153 people
- Sponsor
- Pfizer
COVID19, SARS-CoV-2 Infection
Study of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients: Sarilumab, Azithromycin, Hydroxychloroquine Trial - CORIMUNO-19 - VIRO
The overall objective of the study is to determine the therapeutic effect and tolerance of Sarilumab in combination with Azithromycin and Hydroxychloroquine, compared to Sarilumab only, patients with moderate, severe pneumonia…
- Trial name
- CORIMUNO-VIRO (NCT04341870)
- Testing
- Sarilumab, Azithromycin, Hydroxychloroquine
- Where
- 5 sites in France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Infection
Drug Use Investigation On Zithromac (Azithromycin) In HIV Patients
The investigation will be conducted for the purpose of determining the condition of occurrence of Adverse Events under the actual post-marketing use of Zithromac 600mg Tablet, verifying the therapeutic effects, detecting unknown…
- Trial name
- NCT01227395
- Testing
- Azithromycin
- Volunteers
- 476 people
- Sponsor
- Pfizer
Pregnancy, Infections, Plasmodia
A Safety, Tolerability, Pharmacokinetic and Efficacy Study of Azithromycin Plus Piperaquine as Presumptive Treatment in Pregnant PNG Women
Plasmodium falciparum parasitaemia in pregnancy is associated with maternal anaemia, low birth-weight and increased perinatal mortality.
- Conditions
- Pregnancy, Infections, Plasmodia, Drug Kinetics, Clinical Efficacy
- Trial name
- NCT02575755
- Testing
- Azithromycin plus piperaquine phosphate, Sulfadoxine-pyrimethamine
- Where
- Papua New Guinea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Papua New Guinea Institute of Medical Research
Bacterial Infections
Zithromax-SR 2g, Special Investigation (Regulatory Post Marketing Commitment Plan)
To collect the efficacy and safety information of Zithromax-SR related to their appropriate use in daily practice.
- Trial name
- NCT00998309
- Testing
- Azithromycin SR
- Volunteers
- 502 people
- Sponsor
- Pfizer
Child Mortality
Improving Care Through Azithromycin Research for Infants in Africa
Infectious diseases are among the most common causes of mortality in the over 2.5 million children under 5 years of age (U5) who died in 2018 in sub-Saharan Africa (SSA).
- Trial name
- ICARIA (NCT04235816)
- Testing
- Azithromycin
- Where
- Sierra Leone
- Volunteers
- 20,560 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
RSV Bronchiolitis
Azithromycin to Prevent Wheezing Following Severe Respiratory Syncytial Virus (RSV) Bronchiolitis
This trial is a proof-of-concept pilot study aim to investigate the biologic and clinical effects of early azithromycin treatment in children hospitalized with Respiratory Syncytial Virus (RSV) bronchiolitis.
- Trial name
- APW-RSV (NCT01486758)
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Sickle Cell Disease, Acute Chest Syndrome
A Pilot Study of Azithromycin Prophylaxis for Acute Chest Syndrome in Sickle Cell Disease
Acute chest syndrome (ACS), a lung complication in sickle cell disease (SCD), is the second most common cause of hospitalization and leading cause of death in SCD.
- Trial name
- NCT02630394
- Testing
- Azithromycin
- Where
- 2 sites in United States
- Sponsor
- University of Mississippi Medical Center
Bronchiolitis Obliterans, Bone Marrow Transplantation
Effectiveness of Azithromycin Therapy in Improvement of Symptoms and Lung Function in Patients With Bronchiolitis Obliterans After Bone Marrow Transplantation
Bronchiolitis obliterans syndrome (BOS), an obstructive airway disease as a result of chronic rejection, is one of the major causes of morbidity and mortality in long-term survivors of allogeneic bone marrow transplantation…
- Trial name
- NCT00563251
- Testing
- Azithromycin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Hospital Authority, Hong Kong