Clinical trials: Awakening Early
Sleep Disorder
Interventions for Sleep Problems in Early Childhood
This study will inform the field about underlying mechanisms associated with infant sleep problems and will deepen the understanding of the intervention process.
- Trial name
- NCT01489215
- Testing
- "presence", "checking"
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Out of Hospital Cardiac Arrest, Brain Injury
Therapeutic Hypothermia and eArly Waking
Unconscious survivors of cardiac arrest who are treated with intravenous therapeutic hypothermia for 24 hours will be assessed after 12 hours for appropriateness to be woken early and extubated whilst continuing to receive…
- Trial name
- THAW (NCT03065946)
- Testing
- Early wakening
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Insomnia Disorder
Early Phase 2 Clinical Study of TS-142 in Patients with Insomnia Disorder
Multicenter, randomized, placebo-controlled, 4-arm, 4-period crossover double-blind comparative study.
- Trial name
- NCT04573725
- Testing
- TS-142
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Obstructive Sleep Apnea, Total Knee Arthroplasty
Is the STOP-BANG Predictive of Worsening OSA in the Early Postop Period in Patients Undergoing TJA?
The goal of this study is to determine if the investigators can use the STOP-BANG score to identify those patients at risk for worsening Obstructive Sleep Apnea (OSA) symptoms in the early postoperative period after major…
- Trial name
- NCT02123225
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- United States Naval Medical Center, San Diego
Post Traumatic Stress Disorder, Rape Sexual Assault
Early Psychological Intervention After Rape
Rape is a common cause of post-traumatic stress disorder (PTSD) among women, as around 30-50% will develop PTSD in the aftermath of rape.
- Conditions
- Post Traumatic Stress Disorder, Rape Sexual Assault, Sexual Dysfunctions, Psychological, Pelvic Floor Myalgia
- Trial name
- EIR (NCT05489133)
- Testing
- Modified prolonged exposure
- Where
- 4 sites in Norway
- Volunteers
- 166 people
- Sponsor
- St. Olavs Hospital
Covid19, Respiratory Failure
Proning Early in Awake COVID-19 Hypoxic Respiratory Failure (PREACHR) Study
The aim of this proposal is to study whether proning, a technique that has previously been shown to improve lung function in patients with acute respiratory distress syndrome (ARDS), can prevent those with mild to moderate…
- Trial name
- PREACHR (NCT05130541)
- Testing
- Proning, Supportive Care
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- New York Hospital Queens
COVID-19 Pneumonia
Early Awake Alterning Prone Positioning Combined With Non-invasive Oxygen Therapy in Patients With COVID-19.
Introduction: The disease caused by the new coronavirus (COVID-19) represents a pandemic with significant affectation in our country, generating critical illness in around 5% of the patients who present this disease at an…
- Trial name
- NCT06076109
- Testing
- Prone position, Standard treatment
- Where
- Mexico
- Volunteers
- 137 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Substance-Related Disorders, Substance Use Disorder
Sleep Architecture, Cognitive Function, and Quality of Life During Early Recovery From Substance Use Disorder
This prospective cohort study investigates how sleep disturbances affect cognitive recovery and quality of life during early recovery from substance use disorder (SUD).
- Conditions
- Substance-Related Disorders, Substance Use Disorder, Sleep Wake Disorders, Cognitive Dysfunction
- Trial name
- NCT07852052
- Volunteers
- 34 people
- Sponsor
- Assiut University
Lung Cancer, Sleep Disturbance
The Associations of Sleep Disturbance With Therapy Efficacy and Prognosis of Lung Cancer
This is the prospective, observational cohort study (Nezha) to explore the associations of sleep disturbance with progression, efficacy of immune checkpoint inhibitors (ICIs) and prognosis of Lung Cancer.
- Conditions
- Lung Cancer, Sleep Disturbance, Immune Checkpoint Inhibitors, Cancer, Treatment-Related
- Trial name
- Nezha (NCT06975384)
- Testing
- Exposure: sleep disturbance status
- Where
- China
- Volunteers
- 1,270 people
- Sponsor
- Second Xiangya Hospital of Central South University
AMCI - Amnestic Mild Cognitive Impairment, Sleep Disturbance
Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone
To investigate the effect of trazodone on sleep, hippocampal-dependent memory and hippocampal excitability. The investigators hypothesize that trazodone will improve total sleep time and proportion of time in Slow Wave Sleep…
- Trial name
- REST (NCT05282550)
- Testing
- Trazodone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
REM Sleep Behavior Disorder, Parkinson's Disease
Evolution of RBD in PD
About 60% of Parkinson's Disease (PD) patients have REM sleep Behavior Disorder (RBD), a parasomnia characterized by partial or complete loss of REM sleep muscle atonia and dream-enacting behaviors, usually associated to vivid…
- Trial name
- NCT03047408
- Testing
- Video polysomnography
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Subarachnoid Hemorrhage, Sleep Apnea
Effect of Sleep Apnea on Blood Pressure Control and Outcome Early After Subarachnoid Hemorrhage
In this observational study patients with subarachnoid hemorrhage (SAH) will be screened for sleep apnea (SA) to investigate if SA is associated with impaired blood pressure control and worse clinical outcome early after SAH.
- Trial name
- NCT02724215
- Testing
- Sleep Apnea Screening (Out of Center Polysomnography Device)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bonn
Acute Ischemic Stroke, Sleep Apnea, Obstructive
Ventilation Modalities and Acute Ischemic Stroke
Acute ischemic stroke is the second leading cause of death and disability, and it is also one of the main reasons for the high cost of health care.
- Trial name
- NCT05323266
- Testing
- Nasal Continuous Positive Airway Pressure (nCPAP), High-Flow Nasal Cannula (HFNC)
- Where
- China
- Volunteers
- 195 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized COPD Patients
The purpose of this study is to determine whether early diagnosis of OSA and initiation of and adherence to CPAP therapy in patients hospitalized for chronic obstructive pulmonary disease reduce 30-day hospital readmission rates.
- Trial name
- COPD Readmit (NCT03647462)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Endocrine Responsive Early Breast Cancer
Impact of Adjuvant Treatment With Aromatase Inhibitor on Sleep Disturbances in Postmenopausal Women With Endocrine Responsive Early Breast Cancer
Insomnia is common in Breast cancer patients during adjuvant therapy with aromatase inhibitor. However it is difficult to establish whether it is due to the knowledge of the disease or the treatment administred.
- Trial name
- NCT02166281
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Parkinson Disease, Prodromal Stage
Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands
The goal of this clinical trial is to investigate the feasibility if a remotely administered smartphone app can increase the volume and intensity of physical activity in daily life in patients with isolated Rapid Eye Movement…
- Conditions
- Parkinson Disease, Prodromal Stage, Neurodegenerative Diseases, Parkinsonian Disorders
- Trial name
- Slow-SPEED-NL (NCT06193252)
- Testing
- Increase of physical activity volume and intensity with the use of a motivational smartphone application
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Radboud University Medical Center
Patiens in Early Stage of Chemotherapy
Laughter Yoga- Integrated Virtual Reality Nature Exploration in Early Stage of Chemotherapy
After obtaining informed consent, pre-test applications will be performed on participants in the experimental and control groups following randomization, and information regarding treatment plans will be recorded.
- Trial name
- NCT07798661
- Testing
- laughter yoga-integrated virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Hand Surgery, Wrist Surgery
Early Rehabilitation After Hand or Wrist Ambulatory Surgery : How to Preserve Locomotion at Home Without Rebound Pain?
The purpose of this retrospective study is to compare the analgesic efficacy of Walant " Wide Awake Local Anesthesia No Tourniquet " with lidocaine and bupivacaine versus axillary brachial plexus block using mepivacaïne, both…
- Trial name
- WalantBAX (NCT04306666)
- Testing
- Regional anesthesia
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier