Clinical trials: Avascular Necrosis of Femur Head
Arthrosis, Traumatic Arthritis
The Medacta International SMS Post-Marketing Surveillance Study
This is a Post-Marketing Surveillance of SMS femoral stem prosthesis.
- Conditions
- Arthrosis, Traumatic Arthritis, Rheumatoid Polyarthritis, Congenital Hip Dysplasia
- Trial name
- NCT02748408
- Testing
- SMS femoral stem
- Where
- 4 sites in Austria, Italy and 2 more
- Volunteers
- 550 people
- Sponsor
- Medacta International SA
Osteolysis, Arthroplasty Complications
Plasmafit® Revision Structan® Hip Endoprosthesis Cup
The aim of this observational study is to collect clinical and radiological results of the new Plasmafit® Revision Structan® Hip Endoprosthesis Cup in a standard patient population and when used in routine clinical practice.
- Conditions
- Osteolysis, Arthroplasty Complications, Instability of Prosthetic Joint, Degenerative Osteoarthritis
- Trial name
- NCT04255966
- Testing
- Plasmafit® Revision Structan®
- Where
- 4 sites in Germany
- Volunteers
- 60 people
- Sponsor
- Aesculap AG
Avascular Necrosis of the Femoral Head
Core Decompression Versus Core Decompression With Platelet-Rich Plasma Instillation for Treatment of Early Stage Avascular Necrosis of Femoral Head
This study aims to compare core decompression, a classic technique used for the treatment of avascular necrosis of the femoral head, versus core decompression augmented with PRP instillation, and how it affects the outcome of the…
- Trial name
- NCT07922551
- Testing
- Core Decompression, Platelet rich plasma (PRP)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Osteonecrosis of the Femoral Head, Avascular Necrosis of the Femoral Head
Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis
Osteonecrosis of the femoral head (ONFH) is a debilitating musculoskeletal disease that is characterized by localized death of bone cells and associated cellular elements within the subchondral bone.
- Trial name
- BATON (NCT06123481)
- Testing
- Core Decompression, Core Decompression Procedure with Autologous Bone Marrow Aspirate Concentrate
- Where
- 10 sites in United States
- Volunteers
- 192 people
- Sponsor
- Johns Hopkins University
Osteoarthritis, Hip, Avascular Necrosis of the Femoral Head
Ceramic-on-Ceramic Versus Ceramic-on-HXLPE THA
Methods to reduce the revision rate of total hip arthroplasties (THAs) because of wear-related issues are important to examine, particularly because younger patients have a disproportionately high risk of revision.
- Conditions
- Osteoarthritis, Hip, Avascular Necrosis of the Femoral Head, Arthropathy of Hip, Hip Arthr
- Trial name
- NCT03639532
- Testing
- COC THA, COP THA
- Volunteers
- 148 people
- Sponsor
- Ewha Womans University
Primary Osteoarthritis, Cartilage Degeneration
DEXA Bone Density Analysis of the CoreHip® Prosthesis System
The goal of this interventional post-market follow-up study is to evaluate radiological changes in the diaphyseal bone density (Gruen Zones 3 and 4) within 24 months postoperative in patients treated with CoreHip® primary…
- Conditions
- Primary Osteoarthritis, Cartilage Degeneration, Osteoarthritis, Hip, Inflammatory Arthritis
- Trial name
- CODEX (NCT06632301)
- Testing
- Primary hip replacement with cementless stem
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Aesculap AG
Avascular Necrosis of Femur Head
Implantation of Bone Marrow Cells to Treat Avascular Necrosis of Femoral Head (ANFH)
The purpose of this study is to compare the efficacy of autologous enriched bone marrow cell implantation combined with core decompression to single core decompression for the treatment of avascular necrosis of femoral head.
- Trial name
- NCT01613612
- Testing
- core decompression, Enriched BMCs implantation combined with core decompression
- Volunteers
- 60 people
- Sponsor
- Guangdong Provincial People's Hospital
AVN
Hyperbaric Oxygen Therapy Versus Core Decompression Augmented With Bone Substitute in Pre Collapse of Avascular Necrosis of Femoral Head
Introduction: osteonecrosis of the femoral head is a potentially crippling disorder, which mainly affects the young adults. Core decompression has been used for the treatment of the osteonecrosis of the femur head since was…
- Trial name
- NCT04657653
- Testing
- core decompression
- Where
- Qatar
- Volunteers
- 19 people
- Sponsor
- Hamad Medical Corporation
Avascular Necrosis of Femur, Bone Marrow
Autologous Bone Marrow Concentration for Avascular Necrosis of Femoral Head
This study aims to evaluate the effect of bone marrow concentration on avascular necrosis of femur head by comparing clinical and imaging outcomes between patients receiving core decompression surgery with intraoperative bone…
- Trial name
- NCT03787329
- Testing
- Core decompression surgery with bone marrow concentration, Core decompression surgery
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Pei-Yuan Lee, MD
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
Ceramic-on-Ceramic (COC) 36mm Acetabular Bearing Insert Post Approval Study-New Subjects (COC36mmPAS)
This study is intended to gather short (Pre-operative to 4-years) and mid-term (5-years) information regarding the performance and safety of the commercially available 36mm CERAMAX® Ceramic on Ceramic Total Hip System from a…
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-Traumatic Osteoarthritis of Hip
- Trial name
- COC36mmPAS (NCT02096211)
- Testing
- COC 36mm
- Where
- 13 sites in United States, Canada
- Volunteers
- 172 people
- Sponsor
- DePuy Orthopaedics
Dysplasia of Hip Joint, Hip Osteoarthritis
Multicentre SMS Study - FR
Prospective, multicentre, non controled, non randomised, clinical study to assess the performance and the stability of SMS femoral stem
- Conditions
- Dysplasia of Hip Joint, Hip Osteoarthritis, Traumatic Arthritis of Hip, Avascular Necrosis of Femur Head
- Trial name
- NCT06640764
- Testing
- Total Hip Arthroplasty
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Medacta International SA
Osteoarthritis, Avascular Necrosis
Comparison of Hip Resurfacing to Large Femoral Head Total Hip Arthroplasty
This study evaluates femoral head resurfacing versus a large femoral head (Durom®) total hip system. This is a prospective randomized trial.
- Trial name
- NCT00175487
- Testing
- Hip replacement
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of British Columbia
Degenerative Hip Joint Disease, Post-traumatic Osteoarthritis
Safety and Performance Assessment of the SYMBOL Range of Medical Devices in Patients Underlying Total Hip Arthroplasty
The purpose of this post-market clinical follow up study is to assess the safety and effectiveness of the SYMBOL range of medical devices.
- Conditions
- Degenerative Hip Joint Disease, Post-traumatic Osteoarthritis, Hip Arthritis, Femoral Neck Fractures
- Trial name
- NCT05227924
- Testing
- Total hip arthroplasty (primary or revision)
- Where
- 9 sites in France
- Volunteers
- 747 people
- Sponsor
- Dedienne Sante S.A.S.
Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA)
Study to Evaluate the Safety and Efficacy of OR3O™ Dual Mobility System vs. Conventional Single Bearing Design Total Hip System
The purpose of this study is to compare OR3O™ Dual Mobility System to a conventional, single-bearing design Total Hip System in subjects who undergo Primary THA.
- Conditions
- Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA), Femoral Neck Fractures, Avascular Necrosis of Femoral Head
- Trial name
- OR3O (NCT04941729)
- Testing
- OR3O™ - Dual Mobility System, Conventional
- Where
- 4 sites in China
- Volunteers
- 24 people
- Sponsor
- Smith & Nephew Medical (Shanghai) Ltd
Avascular Necrosis of the Femoral Head
Evaluation of Mesenchymal Stem Cells to Treat Avascular Necrosis of the Hip
The purpose is to assess the safety and feasibility of cellular therapy derived from bone marrow, to help bone healing in patients with avascular necrosis of the hip.
- Trial name
- ORTHO-2 (NCT02065167)
- Testing
- Cultured autologous Mesenchymal Cells
- Where
- 6 sites in France, Germany and 2 more
- Volunteers
- 26 people
- Sponsor
- Universidad Autonoma de Madrid
Osteonecrosis, Avascular Necrosis
Effect of HBOT on Femoral Head Avascular Necrosis (AVN)
The primary objective of this study is to determine whether the Hyperbaric Oxygen Therapy (HBOT) conducted under the Marx Protocol improves pain outcomes when combined with core decompression with autologous bone marrow aspirate…
- Trial name
- NCT06931301
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Yale University
Avascular Necrosis of the Femoral Head
Bone Marrow Cells With Core Decompression for AVN Treatment
Avascular necrosis of the femoral head (AVN) is a progressive pathological process resulting from disruption of blood supply to the femoral head and elevation of intraosseous pressure.
- Trial name
- NCT05982054
- Testing
- core decompression with local bone marrow mononuclear cells injection
- Where
- Iraq
- Volunteers
- 10 people
- Sponsor
- Global Stem Cell Center, Baghdad
Avascular Necrosis, Osteonecrosis
The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head
The purpose of this study is to assess the clinical and x-ray results of patients who are treated with core decompression of the hip and the injection of a bone marrow concentrate and the use of the Bone Graft Substitute Genex®.
- Trial name
- Genex (NCT05706909)
- Testing
- Genex with ABMC
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Femoral Neck Fracture
Porous Tantalum Rods Improve the Hip Joint Function of Patients With Avascular Necrosis of the Femoral Head
To confirm 1) whether, compared with core decompression alone, core decompression with porous tantalum rod implantation improves the hip joint function of patients with avascular necrosis of the femoral head after femoral neck…
- Trial name
- NCT02877472
- Testing
- porous tantalum rod, core decompression
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qinghai University
Osteoarthritis, Rheumatoid Arthritis
Tritanium® Study in Japan
The purpose of this study is to evaluate early fixation and stability of the Tritanium cup. It is expected that the Tritanium® cup will be equal to or better than conventional cementless cups in early fixation/stability and meet…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis of the Femoral Head
- Trial name
- NCT02552069
- Testing
- Tritanium® cup
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Stryker Japan K.K.