Clinical trials: Automated Drug Delivery
Diabete Mellitus, Peripheral (Sensorimotor) Diabetic Polyneuropathy
Neurophysiological, Autonomic, and Sonographic Assessment of Diabetic Peripheral Neuropathy
Diabetic peripheral neuropathy causes pain, sensory loss, and foot risk; multimodal assessment enables earlier diagnosis and improved patient management.
- Trial name
- NCT07306884
- Testing
- Nerve conduction study, Nerve ultrasound, Autonomic assessment
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 1 Diabetes, Type 1 Diabetes Mellitus
Evaluating Glucose Control Using a Next-Generation AID Algorithm in Individuals With T1D
Feasibility study to evaluate the safety and feasibility of Omnipod automated insulin delivery algorithms in individuals with type 1 diabetes.
- Conditions
- Type 1 Diabetes, Type 1 Diabetes Mellitus, Diabetes (DM)
- Trial name
- EVOLUTIONT1D (NCT07593625)
- Testing
- Omnipod M System, Omnipod S
- Where
- New Zealand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Insulet Corporation
Peritoneal Dialysis Associated Peritonitis, Peritoneal Dialysis (PD)
Pharmacokinetics of Meropenem and Aztreonam After Intraperitoneal Administration Via Cycler-therapy in APD Patients Without Peritonitis
Peritoneal dialysis-associated peritonitis (PDAP) remains one of the most serious complications in patients undergoing peritoneal dialysis (PD), contributing significantly to hospitalization, technique failure, and mortality.
- Conditions
- Peritoneal Dialysis Associated Peritonitis, Peritoneal Dialysis (PD), Peritoneal Dialysis, Peritoneal Dialysis, Continuous Ambulatory
- Trial name
- NCT07113574
- Testing
- Meropenem 1000 mg, Aztreonam 2000 mg, automated peritoneal dialysis with following long time dwell
- Where
- Austria
- Volunteers
- 12 people
- Sponsor
- Karl Landsteiner Insitute for Nephrology and Haemato-Oncology
HIV Infections
Viral Load Triggered ART Care in Lesotho
This cluster randomized clinical trial at 18 nurse-led rural health centers in Lesotho will test an automated differentiated service delivery model using viral load results, other clinical characteristics and participants'…
- Trial name
- VITAL (NCT04527874)
- Testing
- VITAL model
- Where
- 18 sites in Lesotho
- Volunteers
- 5,809 people
- Sponsor
- Swiss Tropical & Public Health Institute
Diabetes Mellitus Type 2, Adult-onset Diabetes
Automated SMS-Based Appointment Validation Tool
Medic Mobile conceptualized and proposed the creation of an SMS-based appointment validation tool to automate appointment confirmation and rescheduling.
- Trial name
- NCT01671189
- Testing
- SMS Reminder Software Tool
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Medic Mobile
Liver Diseases, Liver Cancer
Accuracy of the LiverVision® Semi-automated Liver Volumetry Software
The LiverVision® software was designed to provide three-dimensional (3D) visualisation of the liver using Computed Tomography (CT) scans. It provides semi-automated volumetry measurements, vascular structure and territory tools.
- Trial name
- LiverVision (NCT03766633)
- Testing
- Liver volumetry of the graft on CT
- Where
- 3 sites in Germany, Turkey (Türkiye) and 1 more
- Volunteers
- 108 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Obesity Hypoventilation Syndrome (OHS), Chronic Obstructive Lung Disease
Telemedical Assistance in Automatic Titration of Oxygen for Intensive Care Patients
The goal of this clinical trial is to clinically validate a system for the monitoring of patients' respiratory function and automated oxygen treatment proposal using non-invasive ventilation devices in the treatment of intensive…
- Conditions
- Obesity Hypoventilation Syndrome (OHS), Chronic Obstructive Lung Disease, Interstitial Lung Disease, Pneumonia
- Trial name
- Smartassistant (NCT06090149)
- Testing
- PHASE 1 Lowenstein medical BiLevel Prisma 25ST device: withount oxygen support., PHASE 2. Continous/Bilevel positive airway presure with additional oxygen support by Devilbiss 525 KS oxygen concentrator
- Where
- Latvia
- Volunteers
- 30 people
- Sponsor
- Pauls Stradins Clinical University Hospital
Type 1 Diabetes Mellitus
VV-14300 for the Treatment of Type 1 Diabetes
This study is testing VV-14300 in adults with long-standing type 1 diabetes (T1D) whose blood sugar is not well controlled despite using an automated insulin delivery (AID) system.
- Trial name
- RELIEVE (NCT07831798)
- Testing
- VV-14300
- Where
- 2 sites in Canada, New Zealand
- Volunteers
- 29 people
- Sponsor
- Kriya Therapeutics, Inc.
Diabetes Mellitus, Type 1
Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics
The goal of this clinical trial is to determine if transitioning to automated insulin delivery (AID) systems, can improve objectively measured sleep quality and quantity and alleviate cardiovascular risk factors in both children…
- Trial name
- AID-BEYOND (NCT06469593)
- Testing
- Automated insuling delivery system
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetes type1
T1D Closed-loop and Physical Activity
"Physical activity is recognized as beneficial for patients living with type 1 diabetes (T1DM), with a demonstrated effect not only on HbA1c control [1] but also on reducing the incidence of diabetes-related complications [2,3].
- Trial name
- NCT06460558
- Testing
- Type 1 diabetes with insulin infusion system
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Stroke, Cerebral Palsy
Gondola Mechanism of Action
This study will investigate the clinical, functional and neurophysiological effects of automated mechanical peripheral stimulation (AMPS) via the Gondola device administered to patients with chronic stroke, cerebral palsy and…
- Conditions
- Chronic Stroke, Cerebral Palsy, Parkinson's Disease
- Trial name
- NCT05146648
- Testing
- Gondola AMPS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Escalation of Care, Cardiopulmonary Arrest
Early Warning System for Clinical Deterioration on General Hospital Wards
The goal is to develop a two-tiered monitoring system to improve the care of patients at risk for clinical deterioration on general hospital wards (GHWs) at Barnes-Jewish Hospital (BJH).
- Conditions
- Escalation of Care, Cardiopulmonary Arrest, Respiratory Arrest, Severe Sepsis
- Trial name
- NCT01280942
- Testing
- EWS Nursing Alerts, Wireless Remote Sensor
- Where
- United States
- Volunteers
- 20,031 people
- Sponsor
- Washington University School of Medicine
Type 1 Diabetes (T1D)
Utilizing Community Health Workers as Diabetes Technology Coaches for Children With Type 1 Diabetes Using Automated Insulin Delivery
This study uses community health workers (CHW) as diabetes technology coaches for African American children using automated insulin delivery systems but have an HbA1c of 8% or higher.
- Trial name
- CHWs AID Youth (NCT07154251)
- Testing
- Community Health Worker
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University Hospitals Cleveland Medical Center
Sleep Quality
Infant Swing and Sleep-Wake Cycles
This study was planned to determine the effects of automatic baby swing application on the sleep-wake cycle, comfort behaviors and physiological parameters of babies in the neonatal intensive care unit.
- Trial name
- AISS (NCT07284303)
- Testing
- Care: Automatic Baby Swing
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Diabetic Retinopathy, Diabetic Eye Problems
Validation Study of RETINA-AI Galaxy™, an Automated Diabetic Retinopathy Screening Device
Diabetes affects approximately 35 million Americans, each of whom needs at least one retinal exam per year. However, majority do not get their eye exam due to multiple prohibitive factors such as cost, transportation, difficulty…
- Conditions
- Diabetic Retinopathy, Diabetic Eye Problems, Diabetic Macular Edema
- Trial name
- NCT04774822
- Testing
- Color Fundus Photography, Mydriatics Agent, Optical Coherence Tomography (OCT)
- Where
- 3 sites in United States
- Volunteers
- 397 people
- Sponsor
- RETINA-AI Health, Inc.
Dry Eye, Dry Eye Disease (DED)
Telemedicine for Evaluating Dry Eye Disease (DED) Using a Mobile Phone-Attached Portable Automatic Ocular Surface Imaging Device (PAOSID): A Patient-Operated Diagnostic and Continuous Ocular Surface Monitoring (COSM) System
Dry eye disease (DED) is a common eye condition that is becoming more widespread. Detecting it early, keeping track of its progression, and following up regularly can help protect vision and prevent serious complications.
- Trial name
- NCT07341724
- Testing
- Dr Eye
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Diabetes Mellitus, Type 1
An Outpatient Study of Automated Blood Glucose Control With an Insulin-Only Bionic Pancreas
This is an open-label, non-randomized, pilot study to determine the safety and feasibility of the insulin-only bionic pancreas.
- Trial name
- NCT02536950
- Testing
- Fixed set point, Variable set point
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Bruce A. Buckingham
Esophagogastroduodenoscopy
Quality Control of Esophagogastroduodenoscopy Using Real-time EGD Auxiliary System
The aim of our study was to develop an automatic quality-control system and assess the performance of this system in quality control of esophagogastroduodenoscopy.
- Trial name
- NCT03883035
- Testing
- automatic quality-control system
- Where
- China
- Volunteers
- 1,060 people
- Sponsor
- Yanqing Li
Medical Education, Clinical Competence
Intelligent Simulated Patient System for Gastroenterology Education
This randomized controlled trial evaluated a large language model-based Intelligent Simulated Patient System (ISPS) for gastroenterology history-taking education.
- Conditions
- Medical Education, Clinical Competence, History Taking
- Trial name
- NCT07714655
- Testing
- Intelligent Simulated Patient System (ISPS), Conventional Clinical Teaching
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Arrhythmias, Cardiac
CANadian Clinical Evaluation of SpiderFlash Arrhythmia DETECTion in SpiderFlash™ Device
This clinical investigation is a prospective, non-randomized, multi-center pivotal trial. This trial aims to validate the automatic detection features provided by the external long-duration SpiderFlash-t™ Event recorder coupled…
- Trial name
- CAN-DETECT (NCT01218763)
- Where
- 5 sites in Canada
- Volunteers
- 101 people
- Sponsor
- Sorin Group Canada