Clinical trials: Autobiographical Memory
Episodic Memory
In-depth Investigation of Brain Network Interactions
Brain stimulation is a means to potentially remediate symptoms in a range of neurological and psychiatric diseases, however, precise targeting of stimulation is necessary to ensure efficacy.
- Trial name
- BNI (NCT04748146)
- Testing
- Brain stimulation
- Where
- United States
- Sponsor
- Northwestern University
Alcohol Drinking, Drinking Behavior
Neuroimaging Mechanisms by Which Memory and Glucocorticoids Promote Risky Drinking
The purpose of this study is to determine whether hydrocortisone biases formation of alcohol-related memories to potentiate drinking.
- Conditions
- Alcohol Drinking, Drinking Behavior, Episodic Memory, Long-term Memory
- Trial name
- NCT04896489
- Testing
- Hydrocortisone 20 MG
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia Cognition Autobiographical Memory Cognitive Remediation
Cognitive Remediation of Autobiographical Memory in Schizophrenia Using SenseCam®
The aim of the study is to assess the efficiency of SenseCam® in patients with schizophrenia by comparing two cognitive remediation methods of autobiographical memory.Patients and control participants will be invited to carry…
- Trial name
- RéMABSchiz (NCT02038465)
- Testing
- Questionary
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Normal Physiology
Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory
Background: Transcranial magnetic stimulation (TMS) of the brain has been used to change the activity and connections in the brain to improve memory.
- Trial name
- NCT04694131
- Testing
- TMS
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic
Acoustic Stimulation During Sleep: Effects on Memory and p-tau217 in MCI
The goal of this clinical trial is to determine whether acoustic stimulation during sleep can enhance slow-wave sleep (SWS), improve cognitive function, and reduce AD-related pathology in individuals with mild cognitive…
- Conditions
- Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic, Cognitively Unimpaired
- Trial name
- PAS-MCI (NCT07529015)
- Testing
- Plase-Locked Acoustic Stimulation during slow-wave sleep
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Memory Disorders
Development, Standardisation and Standardisation Project for a New Memory Assessment
Episodic memory (EM) is a neuropsychological marker of Alzheimer's disease (AD) (Thomas-Anterion, 2006). Current tests for its assessment do not take into account the identity and emotional aspects of memory (Van der Linden et…
- Trial name
- NEM (NCT06564779)
- Testing
- New memory assessment
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Tours
Behavior
Neural Mechanisms for Reducing Interference During Episodic Memory Formation
Healthy individuals from the University of Oregon and surrounding community will be recruited for participation in behavioral, fMRI and eye tracking experiments that investigate human memory.
- Trial name
- NCT05092100
- Testing
- Visual stimulus similarity, fMRI, Eye tracking
- Where
- United States
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Traumatic Brain Injury, Closed Traumatic Brain Injury
The Effects of Transcranial Direct Current Stimulation (tDCS) and Cognitive Training in Patients With TBI
Long-term sequelae in TBI is a well-recognized burn. We designed a proof of concept study, randomized, double-blind, placebo-controlled to evaluate 36 adult TBI patients.
- Conditions
- Traumatic Brain Injury, Closed Traumatic Brain Injury, Severe Brain Injury
- Trial name
- NCT04540783
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo General Hospital
Aging
Modulation of Episodic Memory Using Theta Burst Stimulation (TBS)
The goal of this study is to evaluate the effect of white matter guided theta burst stimulation on episodic memory task performance in healthy older adults.
- Trial name
- NCT03406195
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Child, Only, Narration
Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Background and study aims: The Eye Movement Desensitization and Reprocessing Group Protocol with Children (EMDR-GP/C) was first developed by Korkmazlar following the Marmara earthquake in Turkey in 1999 and can be adapted for…
- Conditions
- Child, Only, Narration, Memory Dysfunction, Distress, Emotional
- Trial name
- HTC (NCT05319002)
- Testing
- Group EMDR
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Test Anxiety
Influence of Chocolate With Plant Additives on Episodic Memory in Healthy Subjects Experiencing Test Anxiety
Randomized, blind parallel group design. Single intake of 55 g high Epicatechin /Melissa dark chocolate containing 160 mg Epicatechin per 55 g serving or single intake of 55 g low Epicatechin/ oat bran white chocolate containing…
- Trial name
- MaRS-Basel (NCT03382067)
- Testing
- High Epicatechin/ Melissa, Low Epicatechin/ Oat bran
- Where
- Switzerland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Multiple Sclerosis, Relapsing-Remitting, Healthy Controls
The Relationships Between Personal Identity, Autobiographical Memory and Future Thinking in People With Multiple Sclerosis
Personal identity is composed of multiple facets of the self that are constructed and nourished through memories of past experiences (i.e., autobiographical memory) and the imagination of events that may occur in the future…
- Trial name
- SELFSEP (NCT05648292)
- Testing
- Neuropsychological tests and psychological questionnaires
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Schizophrenia
rTMS as a Probe of Episodic Memory Neurocircuitry in Schizophrenia
This will be a single site pilot study. 30 subjects with Early Phase Psychosis (EPP), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past ten years, will be enrolled.
- Trial name
- rTMS-EM (NCT04182113)
- Testing
- 1 Hz rTMS Stimulation
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Huntington Disease, Autobiographical Memory
Autobiographical Memory, Future Thought, and Eye Movements in Huntington's Disease
Huntington's disease (HD) is a hereditary neurodegenerative disorder characterized by progressively worsening motor, cognitive, psychiatric, and behavioral deficits.
- Trial name
- MAMOC-MH (NCT07409597)
- Testing
- neuropsychological tests, Eye tracker use
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Psychosis
The Relationship Between Autobiographical Memory and Motivation
People with a diagnosis of psychosis often experience low motivation and pleasure when thinking about doing future activities. This leads, quite understandably, to doing fewer activities they used to enjoy and not taking up…
- Trial name
- NCT03677635
- Testing
- Guided Autobiographical Memory Recall
- Where
- 2 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- King's College London
Epilepsy Intractable
Memory Retrieval and Encoding Investigated by Neural Stimulation
The purpose of this research is to understand biomarkers of human memory through correlational analyses and to use focal electrical stimulation as a causal manipulation to understand how biomarkers of memory relate to other brain…
- Trial name
- MEMREINS (NCT04286776)
- Testing
- Direct electrical stimulation
- Where
- 11 sites in United States
- Volunteers
- 800 people
- Sponsor
- University of Pennsylvania
Epilepsy Intractable
Neuronal Mechanisms of Human Episodic Memory
The purpose the research is to better understand how the human brain accomplishes the basic cognitive tasks of learning new information, recalling stored information, and making decisions or choices about presented information.
- Trial name
- NCT04500119
- Testing
- Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system; Blackrock Cerestim stimulator
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Cedars-Sinai Medical Center
Down Syndrome, Intellectual Disability
Down Syndrome Memantine Follow-up Study
The purpose of this research study is to learn if the medication Memantine Hydrochloride (the study medication) can help adolescents and young adults with Down syndrome. Dr.
- Trial name
- NCT02304302
- Testing
- Memantine
- Where
- 2 sites in United States, Brazil
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Depression, Mindfulness-Based Stress Reduction
Effects of Mindfulness Training on Memories of Personal Past Events
The purpose of the study was to assess the effects of participation in an online Mindfulness-Based Stress Reduction (MBSR) program on everyday memories of personal past events in individuals with depression vulnerability.
- Trial name
- NCT05121116
- Testing
- Online Mindfulness-Based Stress Reduction (MBSR)
- Where
- United Kingdom
- Volunteers
- 63 people
- Sponsor
- Aleksandra Eriksen Isham
Training Group, Control Group
Efficacy of an Autobiographical Memory Specificity and Savoring Training for the Reduction of Depressive Symptomatology
The effect of autobiographical memory specificity and savoring training on memory specificity, positive affect regulation, well-being and depression symptomatology
- Trial name
- PESCAR (NCT05220618)
- Testing
- Autobiographical Memory Specificity and Savoring Training: PESCAR
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- University of Valencia