Clinical trials: Autobiographical Memory
Memory Impairment
Donepezil Memory Preservation Post ECT
This randomized, placebo-controlled trial will evaluate the use of donepezil compared to placebo to reduce the risk of memory impairment after electroconvulsive therapy (ECT).
- Trial name
- NCT02331771
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Porter Adventist Hospital
Healthy Older Adults
Transcranial Alternating Current Stimulation for the Improvement of Episodic Memory in Healthy Older Adults
Memory complaints are a common symptom among Subjective Cognitive Decline, Mild Cognitive Impairment and Alzheimer disease. Indeed, episodic memory and Alzheimer disease are highly sensitive to aging.
- Trial name
- NCT06284720
- Testing
- Gamma tACS (40 Hz) over the precuneus
- Where
- Portugal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidade Católica Portuguesa
Depression
Enhancing the Effectiveness of Electroconvulsive Therapy in Severe Depression
Electroconvulsive therapy (ECT) is the most powerful antidepressant treatment available and is often life-saving. There are concerns, however, that standard bitemporal ECT (the most commonly used form of ECT worldwide) causes…
- Trial name
- EFFECT-Dep (NCT01907217)
- Testing
- ECT Mecta 5000M, Methohexitone, Suxamethonium
- Where
- Ireland
- Volunteers
- 138 people
- Sponsor
- St Patrick's Hospital, Ireland
Amnestic Mild Cognitive Impairment, Traumatic Brain Injury
Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury
The study will examine the efficacy of high definition transcranial direct current stimulation (HD-tDCS) and its influence on episodic memory in patients with amnestic mild cognitive impairment and a history of Traumatic brain…
- Conditions
- Amnestic Mild Cognitive Impairment, Traumatic Brain Injury, Mild Traumatic Brain Injury
- Trial name
- NCT04504630
- Testing
- High Definition Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Texas Southwestern Medical Center
Psilocybin, Music Intervention
PRoMiSS: Psilocybin and the Role of Music in Set and Setting
The goal of this clinical trial is to understand how personally meaningful, autobiographically salient music compares to standardized playlists when combined with psilocybin in healthy adults ages 21 to 75.
- Trial name
- PRoMiSS (NCT07180108)
- Testing
- Psilocybin (high dose), Playlist 1, Playlist 2
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Substance Use Disorder (SUD)
How Avatar Can Enhance Autobiographical Memory of Patients With Substance Use Disorder
The goal of this study is to investigate whether the use of artificial intelligence platforms can promote the retrieval of specific positive autobiographical memories.
- Trial name
- NCT06806943
- Testing
- avatar-based interactions
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Le.L.A.T. Lega Lotta Aids E Tossicodipendenza
Panic Disorder
Imagery Rescripting for Traumatic Panic Attack Memories
The current project consists of two studies investigating the phenomenological characteristics, centrality levels, and traumatic symptoms of panic attack memories, while testing the effectiveness of the Imagery Rescripting (ImRs)…
- Trial name
- NCT07769996
- Testing
- Imagery Rescripting
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- İmge eylem yılmaz namlı
Depressive Disorder, Depression
The Danish Neuropsychological Study of the Adverse Effects of ECT
The main purpose of this study is to investigate the adverse cognitive side-effects of electroconvulsive therapy (ECT). The second aim is to investigate the mechanisms of effect of ECT.
- Conditions
- Depressive Disorder, Depression, Cognitive Dysfunction, Electroconvulsive Therapy
- Trial name
- DANSECT (NCT04160286)
- Testing
- Electroconvulsive therapy
- Where
- Denmark
- Volunteers
- 73 people
- Sponsor
- University of Copenhagen
Schizophrenia
Autobiographical Memory Organization in Schizophrenia
The aim of the study is to investigate the temporal organization of autobiographical memory in patients with schizophrenia. Patients and control participants will be invited separately to participate in a 1hour walk in the city…
- Trial name
- AMOrSchiz (NCT02570594)
- Testing
- questionary
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Borderline Personality Disorder
Assessment of Sense of Identity in Patients Diagnosed With Borderline Personality Disorder. A Pilot Study
One of the key features and long considered a fundamental element of Borderline Personality Disorder is the disruption of identity.
- Trial name
- MASB (NCT04948905)
- Testing
- Evaluation using the Self-Defining Memory Questionnaire
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Suicidal Ideation, Mental Health Disorder
An Autobiographical Memory-Based Intervention for Suicidality
The study involves a short therapy intervention for people who are experiencing thoughts of suicide. The intervention will focus upon different memories from the person's life.
- Trial name
- NCT06225531
- Testing
- Autobiographical Memory Based Intervention
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment
Effects of Combined Aerobic and Cognitive Training in a Simultaneous or Sequential Paradigm on Cognition and Brain Functional Activity in Patients with AMCI
Mild Cognitive Impairment (MCI) is a condition in which patients show an objective evidence of impairment in one or more cognitive domains but a spared independence in daily functional abilities.
- Conditions
- Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment, Neurodegenerative Dementia, Neurodegenerative Disease
- Trial name
- NCT06755164
- Testing
- Simultaneous aerobic and cognitive training (SIM), Sequential aerobic and cognitive training (SEQ)
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Episodic Memory Retrieval
rTMS Brain Stimulation and Cognition
This study will use repetitive transcranial magnetic stimulation (rTMS) (a way to use a powerful magnet to cause temporary impairment to the function of a brain region) to test whether certain parts of the brain are necessary to…
- Trial name
- NCT04244682
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stephan Hamann
Healthy
Influence of CBD on Episodic Memory in Healthy Subjects
Placebo controlled, randomized, double blind, cross-over design. Single vape of 0.25ml 5% CBD e-liquid (12.5mg CBD) and single vape of 0.25ml e-liquid, tastes like lemon and madeleine. 15min vape time each.
- Trial name
- CoIL-Basel (NCT03627117)
- Testing
- Verum
- Where
- Switzerland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Alzheimer Disease
Multiregional rtfMRI Neurofeedback for the Prevention of Alzheimer's Disease (NPAD)
This study aims to predict cognitive decline using a performance endophenotype of neuro-feedback based on functional magnetic resonance imaging in real time in a population at risk for Alzheimer's disease (AD).
- Trial name
- NPAD (NCT03173846)
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Dementia With Lewy Bodies, Alzheimer Disease
Self and Autobiographical Memory in Dementia With Lewy Bodies and Alzheimer Disease: a Behavioral and Multimodal Neuroimaging Study
The present project aims at exploring different components of Self-consciousness or 'the Self', such as autobiographical memory, self-concept and subjective sense of Self, in dementia with Lewy Bodies (DLB) compared to…
- Conditions
- Dementia With Lewy Bodies, Alzheimer Disease, Self, Autobiographical Memory
- Trial name
- SELF-MCL (NCT04616287)
- Testing
- Neuropsychological assessment and Multimodal brain MRI
- Where
- France
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Emotion Regulation, Mood Induction
Effectiveness of Personal Relevance of Visual Autobiographical Stimuli in Positive Emotions Induction
Background: The ability to retrieve specific memories is a cognitive and emotional protective factor. Among the most effective techniques to generate autobiographical memories is the use of audio-visual stimuli, particularly…
- Conditions
- Emotion Regulation, Mood Induction, Autobiographical Memory, Ageing
- Trial name
- NCT04251104
- Testing
- Images' personal relevance effectiveness in objective and subjective mood recovery
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Mild Cognitive Impairment
Improvement of Memory in Mild Cognitive Impairment
The Clinical Trial will systematically examine the feasibility of remote, caregiver-led tACS for older adults with memory deficits and evaluate whether repeated tACS leads to sustained improvement of neuronal activity and memory…
- Trial name
- NCT05708001
- Testing
- transcranial alternating current stimulation (tACS), high-density electroencephalography (hdEEG), Montreal Cognitive Assessment (MoCA)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lucie Bréchet
Mental Disorders
Effects of Emotion on Episodic Memory in Typically Developing Children and Children With Williams-Beuren Syndrome
It's well established in the literature that emotional events are more likely to be remembered than neutral events. Although this Emotional Enhancement of Memory (EEM) has been well demonstrated in the adult literature, little is…
- Trial name
- EEM-TAdev (NCT03688516)
- Testing
- Manipulation of valence and modality, Spatial and recognition memory, Source and content memory
- Where
- France
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Alzheimer Disease, Mild Cognitive Impairment
Memory Enhancement Using Transcranial Alternating Current Stimulation
The 32 million Alzheimer's disease (AD) and 69 million prodromal AD patients worldwide contribute to a large economic burden. Effective and safe therapies that slow or prevent the progression from mild cognitive impairment (MCI)…
- Trial name
- Memento (NCT06202872)
- Testing
- Gamma (40 Hz) tACS at the precuneus region
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Amsterdam UMC, location VUmc