Clinical trials: Autistic Disorder
22q13 Deletion Syndrome, Phelan-McDermid Syndrome
Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)
The purpose of this study is to pilot the use of Insulin-Like Growth Factor-1 (IGF-1) treatment in 22q13 Deletion Syndrome (Phelan-McDermid Syndrome) caused by SHANK3 gene deficiency in order to evaluate safety, tolerability, and…
- Trial name
- NCT01525901
- Testing
- Insulin-Like Growth Factor-1 (IGF-1), Normal saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder
Measuring Brain Inflammation in Autism
Autism spectrum disorders (ASD) are highly disabling, persistent neurodevelopmental disorders. There are no available treatments for core symptoms of ASD or biologically-based clinical biomarkers.
- Trial name
- NCT03117530
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Improving Outcomes in Autism: Community Implementation of Stepped Transition in Education Program
The goal of this study is to conduct the first community-based implementation of the STEPS program and test feasibility and preliminary impact.
- Trial name
- NCT05581069
- Testing
- STEPS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama, Tuscaloosa
Autism Spectrum Disorder
INtranasal OXyTocin for the Treatment of Autism Spectrum Disorders
There is substantial evidence from animal model and healthy control data, that oxytocin is involved in the modulation of social cognition.
- Trial name
- INOXT (NCT01788072)
- Testing
- Intranasal Oxytocin
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder (ASD)
Modified and Context-Focused Sports Intervention in Adolescents With Autism: Study Protocol
Adolescents with Autism Spectrum Disorder (ASD) typically engage less in physical activities than their typically developing peers, influenced by intrinsic and extrinsic factors.
- Trial name
- ASD (NCT06916988)
- Testing
- Sports Stars Brazil, context-centered therapy
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Federal University of Minas Gerais
Autism
Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
The goal of this proposed trial will modify an existing toothbrushing app for teens with autism and compare toothbrushing outcomes with a control app.
- Trial name
- NCT06208722
- Testing
- Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Washington
Autism Spectrum Disorder
Randomized Double-blind Clinical Trial With L.Reuteri Supplementation in Children With Autism Spectrum Disorder
The aim of this study is to assess the effects of a 6-months probiotic supplementation on behavioral profiles, microbiota and metabolic profiles, inflammatory biomarkers, gastrointestinal disturbances, in children with Autism…
- Trial name
- NCT04293783
- Testing
- L.Reuteri
- Where
- 2 sites in Italy
- Volunteers
- 43 people
- Sponsor
- University of Rome Tor Vergata
Autism Spectrum Disorder, Anxiety Disorders
DINO RCT - Treating Anxiety in Children With Autism
Anxiety is prevalent in young children, under 7 years of age, with autism. Yet, few studies have examined anxiety interventions for this age range, and only one anxiety treatment study has included young children with cognitive…
- Trial name
- NCT06066983
- Testing
- DINOSAUR, Psychoeducation
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism
Android Mobile Devices to Assist Routine Anticipation for Autistic Children
The objective of this work is to develop an application to run on a mobile device Android tablet that features visual routines for autistic children.
- Trial name
- NCT02591459
- Testing
- Using the app to assist routine anticipation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Mogi das Cruzes
Child Autism
Effect of Modified Dental Visual Aids on Behavior Management During Dental Treatment in Children With Autism Spectrum Disorder
There is a need to find an approach that is appropriate for managing children with Autism Spectrum Disorder in the dental clinic, to manage their behaviour and decrease their anxiety in this research we will apply our modified…
- Trial name
- NCT04576559
- Testing
- Modified dental visual aids, Regular dental visual aids
- Where
- Saudi Arabia
- Volunteers
- 64 people
- Sponsor
- King Abdulaziz University
Autism Spectrum Disorder
Effect of a Motor Support Program in Children With Autism
This study examined a motor support program applied for 40 minutes, two days per week, over a period of 12 weeks in children aged 4-6 years diagnosed with autism spectrum disorder.
- Trial name
- NCT07321561
- Testing
- Motor Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Istanbul Aydın University
Autism Spectrum Disorder
Structured Function-Based Elopement Treatment Program
This study aims to extend the researchers' prior work on Function-Based Elopement Treatment (FBET) with a randomized controlled trial to evaluate the efficacy of FBET in 76 children with autism spectrum disorder (ASD) and…
- Trial name
- FBET (NCT03899831)
- Testing
- Function-Based Elopement Treatment (FBET), Parent Education Program (PEP)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Emory University
Maternal Depression
Feasibility of Implementing a Mental Health Care Program and Home-based Training for Mothers of Children With Autism Spectrum Disorder in an Urban Population in Bangladesh
Background (brief): The global burden of depression accounts for 2.5% of global DALYs, and in South Asia the estimate is 13.3 % of DALYs per 100,000 populations.
- Trial name
- NCT03025646
- Testing
- Mental Health care services & home based training
- Where
- Bangladesh
- Volunteers
- 78 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Angelman Syndrome
Study of the Prevalence of Autistic Traits in Angelman Syndrome
The goal of this observational cross-sectional study is to establish the prevalence of autism spectrum disorder in children and adolescents with Angelman syndrome.
- Trial name
- NCT06337383
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder, Autism
Multisensory Environment Room in Children With Autism Spectrum Disorder
To investigate the effect of multisensory environment room on behavior in children with autism spectrum disorder age 3-5 years old. The children will be randomized into 2 groups: the experimental and the control group.
- Trial name
- NCT05752994
- Testing
- Training in the multisensory room environment, Home program
- Where
- 2 sites in Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Eating Disorders
Eating Disorders and Autism Spectrum Disorders
This is an observational study where patients with eating disorders (ED) are compared with healthy controls without eating disorder (HC) regarding eating disorders features and autism spectrum features.
- Trial name
- NCT04564170
- Where
- Spain
- Volunteers
- 135 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Anxiety, Autism Spectrum Disorder
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
Anxiety is very common in autistic youth. Recently, an intervention has been created by the investigators to target these symptoms in autistic youth in a community setting.
- Conditions
- Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder
- Trial name
- NCT06046170
- Testing
- Cognitive Behavioral Therapy, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder, Parents
Clinicianless Training in Autism Treatment: An Adaptive Online Parent Education Program
This project will examine the feasibility, acceptability, and preliminary efficacy of using a smartphone app-based parent training program focused on early autism intervention strategies.
- Trial name
- NCT04992169
- Testing
- Smartphone-App Parent Training in Pivotal Response Treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of California, Santa Barbara
Autism Spectrum Disorder
A Prospective, Single-Center, Single-Arm, Investigator-Initiated Exploratory Clinical Trial to Assess the Safety of Repetitive Transcranial Magnetic Stimulation for Children and Adolescents With Autism Spectrum Disorder
This is a prospective, single-center, single-arm, investigator-initiated exploratory clinical trial aimed at evaluating the safety and exploring the efficacy of a medical electromagnetic stimulator delivering low-frequency…
- Trial name
- NCT06982586
- Testing
- Repetitive transcranial magentic stimulation
- Volunteers
- 18 people
- Sponsor
- Bundang CHA Hospital
Autistic Disorder
Aripiprazole Oral Solution in the Treatment of Children and Adolescents With Autistic Disorder
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, safety, tolerability and the steady-state plasma trough concentration of aripiprazole flexible-dosed in children…
- Trial name
- NCT03487770
- Testing
- Aripiprazole Oral Solution
- Where
- China
- Volunteers
- 111 people
- Sponsor
- Otsuka Beijing Research Institute